Steven Rodems

Affiliations

Retrophin, Inc., San Diego, CA, USA.

Publications (14)

Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene.

Stem cell research

Avec: Rong Li , Manisha Pradhan , Miao Xu , Amanda Baskfield , Atena Farkhondeh , Yu-Shan Cheng , Jeanette Beers , Jizhong Zou , Chengyu Liu , Matthew Might , Steven Rodems , Wei Zheng

An induced pluripotent stem cell line (TRNDi010-C) from a patient carrying a homozygous p.R401X mutation in the NGLY1 gene.

Stem cell research

Avec: Shu Yang , Yu-Shan Cheng , Rong Li , Manisha Pradhan , Junjie Hong , Jeanette Beers , Jizhong Zou , Chengyu Liu , Matt Might , Steven Rodems , Wei Zheng

An induced pluripotent stem cell line (NCATS-CL9075) from a patient carrying compound heterozygote mutations, p.R390P and p.L318P, in the NGLY1 gene.

Stem cell research

Avec: Manisha Pradhan , Atena Farkhondeh , Yu-Shan Cheng , Miao Xu , Jeanette Beers , Jizhong Zou , Chengyu Liu , Matthew Might , Steven Rodems , Karsten Baumgärtel , Wei Zheng

Generation of an Alagille Syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi036-A) carrying a heterozygous mutation (p.Cys693*) in the JAG1 gene.

Stem cell research

Avec: Omer Hatim , Miao Xu , Ivan Pavlinov , Kaari Linask , Jeanette Beers , Jizhong Zou , Chengyu Liu , Steven Rodems , Karsten Baumgärtel , Melissa A Gilbert , Nancy B Spinner , Catherine Chen , Wei Zheng

Induced pluripotent stem cells for neural drug discovery.

Drug discovery today

Avec: Atena Farkhondeh , Rong Li , Kirill Gorshkov , Kevin G Chen , Matthew Might , Steven Rodems , Donald C Lo , Wei Zheng

Generation of Alagille syndrome derived induced pluripotent stem cell line carrying heterozygous mutation in the JAGGED-1 gene at splicing site (Chr20: 10,629,709C>A) before exon 11.

Stem cell research

Avec: Wei Zhu , Yu-Shan Cheng , Miao Xu , Atena Farkhondeh , Jeanette Beers , Jizhong Zou , Chengyu Liu , Karsten Baumgaertel , Steven Rodems , Wei Zheng

Generation of two gene corrected human isogenic iPSC lines (NCATS-CL6104 and NCATS-CL6105) from a patient line (NCATS-CL6103) carrying a homozygous p.R401X mutation in the NGLY1 gene using CRISPR/Cas9.

Stem cell research

Avec: Ivan Pavlinov , Atena Farkhondeh , Shu Yang , Miao Xu , Yu-Shan Cheng , Jeanette Beers , Jizhong Zou , Chengyu Liu , Matthew Might , Steven Rodems , Karsten Baumgärtel , Wei Zheng

Therapeutics Development for Alagille Syndrome.

Frontiers in pharmacology

Avec: Phillip Sanchez , Atena Farkhondeh , Ivan Pavlinov , Karsten Baumgaertel , Steven Rodems , Wei Zheng

Mechanism of action and impact of thiol homeostasis on efficacy of an enzyme replacement therapy for classical homocystinuria.

Redox biology

Avec: Thilo Magnus Philipp , Teodoro Bottiglieri , Wilmelenne Clapper , Kai Liu , Steve Rodems , Csaba Szabo , Tomas Majtan

Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936 T > A) mutation in JAGGED-1.

Stem cell research

Avec: Brianna M Brooks , Manisha Pradhan , Yu-Shan Cheng , Kirill Gorshkov , Atena Farkhondeh , Catherine Z Chen , Jeanette Beers , Chengyu Liu , Karsten Baumgaertel , Steven Rodems , Wei Zheng

High-throughput protein modification quantitation analysis using intact protein MRM and its application on hENGase inhibitor screening.

Talanta

Avec: Dingyin Tao , Miao Xu , Atena Farkhondeh , Andrew P Burns , Steven Rodems , Matthew Might , Wei Zheng , Christopher A LeClair

An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation.

Advanced therapeutics

Avec: Trevor Sasserath , Ashley L Robertson , Roxana Mendez , Tristan T Hays , Ethan Smith , Helena Cooper , Nesar Akanda , John W Rumsey , Xiufang Guo , Atena Farkhondeh , Manisha Pradhan , Karsten Baumgaertel , Matthew Might , Steven Rodems , Wei Zheng , James J Hickman

Allelic prevalence and geographic distribution of cerebrotendinous xanthomatosis.

Orphanet journal of rare diseases

Avec: Tiziano Pramparo , Robert D Steiner , Steve Rodems , Celia Jenkinson

Generation and characterization of NGLY1 patient-derived midbrain organoids.

Frontiers in cell and developmental biology

Avec: Joshua Abbott , Mitali Tambe , Ivan Pavlinov , Atena Farkhondeh , Ha Nam Nguyen , Miao Xu , Manisha Pradhan , Tate York , Matthew Might , Karsten Baumgärtel , Steven Rodems , Wei Zheng

Réseau de co-auteurs

Wei Zheng 12 collaborations

Atena Farkhondeh 10 collaborations

Miao Xu 7 collaborations

Jeanette Beers 7 collaborations

Chengyu Liu 7 collaborations

Matthew Might 7 collaborations

Manisha Pradhan 6 collaborations

Yu-Shan Cheng 6 collaborations

Jizhong Zou 6 collaborations

Karsten Baumgärtel 4 collaborations

Ivan Pavlinov 4 collaborations

Karsten Baumgaertel 4 collaborations

Rong Li 3 collaborations

Shu Yang 2 collaborations

Kirill Gorshkov 2 collaborations

Steve Rodems 2 collaborations

Amanda Baskfield 1 collaboration

Junjie Hong 1 collaboration

Matt Might 1 collaboration

Omer Hatim 1 collaboration

Kaari Linask 1 collaboration

Melissa A Gilbert 1 collaboration

Nancy B Spinner 1 collaboration

Catherine Chen 1 collaboration

Kevin G Chen 1 collaboration

Donald C Lo 1 collaboration

Wei Zhu 1 collaboration

Phillip Sanchez 1 collaboration

Thilo Magnus Philipp 1 collaboration

Teodoro Bottiglieri 1 collaboration

Wilmelenne Clapper 1 collaboration

Kai Liu 1 collaboration

Csaba Szabo 1 collaboration

Tomas Majtan 1 collaboration

Brianna M Brooks 1 collaboration

Catherine Z Chen 1 collaboration

Dingyin Tao 1 collaboration

Andrew P Burns 1 collaboration

Christopher A LeClair 1 collaboration

Trevor Sasserath 1 collaboration

Ashley L Robertson 1 collaboration

Roxana Mendez 1 collaboration

Tristan T Hays 1 collaboration

Ethan Smith 1 collaboration

Helena Cooper 1 collaboration

Nesar Akanda 1 collaboration

John W Rumsey 1 collaboration

Xiufang Guo 1 collaboration

James J Hickman 1 collaboration

Tiziano Pramparo 1 collaboration

Robert D Steiner 1 collaboration

Celia Jenkinson 1 collaboration

Joshua Abbott 1 collaboration

Mitali Tambe 1 collaboration

Ha Nam Nguyen 1 collaboration

Tate York 1 collaboration