Sumiko Ohnami

Affiliations

Cancer Diagnostics Research Division, Shizuoka Cancer Center Research Institute, Sunto-gun, Shizuoka, 411-8777, Japan.

Publications (29)

Whole exome sequencing and deep sequencing of esophageal squamous cell carcinoma and adenocarcinoma in Japanese patients using the Japanese version of the Genome Atlas, JCGA.

Esophagus : official journal of the Japan Esophageal Society

Avec: Eisuke Booka , Yasuhiro Tsubosa , Tomoya Yokota , Shuhei Mayanagi , Kenjiro Ishii , Kenichi Urakami , Keiichi Ohshima , Shumpei Ohnami , Takeshi Nagashima , Ken Yamaguchi

Mutational concordance analysis provides supportive information for double cancer diagnosis.

BMC cancer

Avec: Keiichi Hatakeyama , Takeshi Nagashima , Akifumi Notsu , Keiichi Ohshima , Sumiko Ohnami , Shumpei Ohnami , Yuji Shimoda , Akane Naruoka , Koji Maruyama , Akira Iizuka , Tadashi Ashizawa , Hirotsugu Kenmotsu , Tohru Mochizuki , Kenichi Urakami , Yasuto Akiyama , Ken Yamaguchi

Molecular genetic positioning of small intestine and papilla of Vater carcinomas including clinicopathological classification.

Cancer medicine

Avec: Masanori Nakamura , Yukiyasu Okamura , Keiichi Ohshima , Teiichi Sugiura , Ryo Ashida , Katsuhisa Ohgi , Etsuro Bando , Keiichi Fujiya , Akio Shiomi , Hiroyasu Kagawa , Taisuke Imamura , Goro Nakayama , Yasuhiro Kodera , Katsuhiko Uesaka , Nobuyuki Ohike , Tomoko Norose , Keiko Sasaki , Takashi Sugino , Sumiko Ohnami , Takeshi Nagashima , Kenichi Urakami , Yasuto Akiyama , Ken Yamaguchi

Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse gastric cancer with low tumor content.

Scientific reports

Avec: Keiichi Hatakeyama , Koji Muramatsu , Takeshi Nagashima , Hiroyuki Ichida , Yuichi Kawanishi , Ryutaro Fukumura , Keiichi Ohshima , Yuji Shimoda , Sumiko Ohnami , Shumpei Ohnami , Koji Maruyama , Akane Naruoka , Hirotsugu Kenmotsu , Kenichi Urakami , Yasuto Akiyama , Takashi Sugino , Ken Yamaguchi

Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors.

Cancer science

Avec: Keiichi Ohshima , Keiichi Fujiya , Takeshi Nagashima , Sumiko Ohnami , Keiichi Hatakeyama , Kenichi Urakami , Akane Naruoka , Yuko Watanabe , Sachi Moromizato , Yuji Shimoda , Shumpei Ohnami , Masakuni Serizawa , Yasuto Akiyama , Masatoshi Kusuhara , Tohru Mochizuki , Takashi Sugino , Akio Shiomi , Yasuhiro Tsubosa , Katsuhiko Uesaka , Masanori Terashima , Ken Yamaguchi

Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy.

Cancer science

Avec: Keiichi Hatakeyama , Takeshi Nagashima , Keiichi Ohshima , Sumiko Ohnami , Shumpei Ohnami , Yuji Shimoda , Masakuni Serizawa , Koji Maruyama , Akane Naruoka , Yasuto Akiyama , Kenichi Urakami , Masatoshi Kusuhara , Tohru Mochizuki , Ken Yamaguchi

Genomic profiling of multiple tissues in two patients with multiple endocrine neoplasia type 1.

Biomedical research (Tokyo, Japan)

Avec: Akane Naruoka , Sumiko Ohnami , Takeshi Nagashima , Masakuni Serizawa , Keiichi Hatakeyama , Keiichi Ohshima , Shumpei Ohnami , Kenichi Urakami , Yasue Horiuchi , Yoshimi Kiyozumi , Hiroyuki Matsubayashi , Masato Abe , Takuma Ohishi , Toru Kameya , Takashi Sugino , Tetsuro Onitsuka , Mitsuhiro Isaka , Yasuhisa Ohde , Teiichi Sugiura , Takaaki Ito , Katsuhiko Uesaka , Yasuto Akiyama , Masatoshi Kusuhara , Ken Yamaguchi

Development of two 410-cancer-gene panel tests for solid tumors and liquid biopsy based on genome data of 5,143 Japanese cancer patients.

Biomedical research (Tokyo, Japan)

Avec: Yuji Shimoda , Takeshi Nagashima , Kenichi Urakami , Fukumi Kamada , Sou Nakatani , Maki Mizuguchi , Masakuni Serizawa , Keiichi Hatakeyama , Keiichi Ohshima , Tohru Mochizuki , Sumiko Ohnami , Shumpei Ohnami , Takeshi Kawakami , Kentaro Yamazaki , Haruyasu Murakami , Hirotsugu Kenmotsu , Akio Shiomi , Yasuto Akiyama , Ken Yamaguchi

Japanese version of The Cancer Genome Atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients.

Cancer science

Avec: Takeshi Nagashima , Ken Yamaguchi , Kenichi Urakami , Yuji Shimoda , Sumiko Ohnami , Keiichi Ohshima , Tomoe Tanabe , Akane Naruoka , Fukumi Kamada , Masakuni Serizawa , Keiichi Hatakeyama , Kenya Matsumura , Shumpei Ohnami , Koji Maruyama , Tohru Mochizuki , Masatoshi Kusuhara , Akio Shiomi , Yasuhisa Ohde , Masanori Terashima , Katsuhiko Uesaka , Tetsuro Onitsuka , Seiichiro Nishimura , Yasuyuki Hirashima , Nakamasa Hayashi , Yoshio Kiyohara , Yasuhiro Tsubosa , Hirohisa Katagiri , Masashi Niwakawa , Kaoru Takahashi , Hiroya Kashiwagi , Masahiro Nakagawa , Yuji Ishida , Takashi Sugino , Mitsuru Takahashi , Yasuto Akiyama

Metachronous ovarian endometrioid carcinomas in a patient with a PTEN variant: case report of incidentally detected Cowden syndrome.

BMC cancer

Avec: Hiroyuki Matsubayashi , Satomi Higashigawa , Yoshimi Kiyozumi , Yasue Horiuchi , Yasuyuki Hirashima , Nobuhiro Kado , Masato Abe , Takuma Ohishi , Sumiko Ohnami , Kenichi Urakami , Ken Yamaguchi

JCGA: the Japanese version of the Cancer Genome Atlas and its contribution to the interpretation of gene alterations detected in clinical cancer genome sequencing.

Human genome variation

Avec: Masakuni Serizawa , Maki Mizuguchi , Kenichi Urakami , Takeshi Nagashima , Keiichi Ohshima , Keiichi Hatakeyama , Sumiko Ohnami , Shumpei Ohnami , Koji Maruyama , Tadashi Ashizawa , Akira Iizuka , Yasue Horiuchi , Akane Naruoka , Hirotsugu Kenmotsu , Yasuto Akiyama , Ken Yamaguchi

Sharing genetic test results of germline pathogenic variants of hereditary cancer with relatives: A single-center cross-sectional study.

Japanese journal of clinical oncology

Avec: Naomi Fukuzaki , Yoshimi Kiyozumi , Satomi Higashigawa , Yasue Horiuchi , Maki Mizuguchi , Hiroyuki Matsubayashi , Seiichiro Nishimura , Keita Mori , Akifumi Notsu , Izumi Suishu , Sumiko Ohnami , Masatoshi Kusuhara , Ken Yamaguchi , Ardith Z Doorenbos , Yuko Takeda

Hepatocellular carcinoma after a sustained virological response by direct-acting antivirals harbors TP53 inactivation.

Cancer medicine

Avec: Taisuke Imamura , Yukiyasu Okamura , Keiichi Ohshima , Katsuhiko Uesaka , Teiichi Sugiura , Takaaki Ito , Yusuke Yamamoto , Ryo Ashida , Katsuhisa Ohgi , Shimpei Otsuka , Sumiko Ohnami , Takeshi Nagashima , Keiichi Hatakeyama , Yuko Kakuda , Takashi Sugino , Kenichi Urakami , Yasuto Akiyama , Ken Yamaguchi

Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes.

Scientific reports

Avec: Sumiko Ohnami , Akane Naruoka , Mitsuhiro Isaka , Maki Mizuguchi , Sou Nakatani , Fukumi Kamada , Yuji Shimoda , Ai Sakai , Keiichi Ohshima , Keiichi Hatakeyama , Kouji Maruyama , Yasuhisa Ohde , Hirotsugu Kenmotsu , Toshiaki Takahashi , Yasuto Akiyama , Takeshi Nagashima , Kenichi Urakami , Shumpei Ohnami , Ken Yamaguchi

Disclosure of secondary findings in exome sequencing of 2480 Japanese cancer patients.

Human genetics

Avec: Yasue Horiuchi , Hiroyuki Matsubayashi , Yoshimi Kiyozumi , Seiichiro Nishimura , Satomi Higashigawa , Nobuhiro Kado , Takeshi Nagashima , Maki Mizuguchi , Sumiko Ohnami , Makoto Arai , Kenichi Urakami , Masatoshi Kusuhara , Ken Yamaguchi

Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients.

Cancer science

Avec: Keiichi Hatakeyama , Takeshi Nagashima , Keiichi Ohshima , Sumiko Ohnami , Shumpei Ohnami , Yuji Shimoda , Akane Naruoka , Koji Maruyama , Akira Iizuka , Tadashi Ashizawa , Tohru Mochizuki , Kenichi Urakami , Yasuto Akiyama , Ken Yamaguchi

Germline mismatch repair gene variants analyzed by universal sequencing in Japanese cancer patients.

Cancer medicine

Avec: Yoshimi Kiyozumi , Hiroyuki Matsubayashi , Yasue Horiuchi , Satomi Higashigawa , Takuma Oishi , Masato Abe , Sumiko Ohnami , Kenichi Urakami , Takeshi Nagashima , Masatoshi Kusuhara , Hidehiko Miyake , Ken Yamaguchi

Role of Tumor Mutation Burden Analysis in Detecting Lynch Syndrome in Precision Medicine: Analysis of 2,501 Japanese Cancer Patients.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Avec: Yoshimi Kiyozumi , Hiroyuki Matsubayashi , Satomi Higashigawa , Yasue Horiuchi , Nobuhiro Kado , Yasuyuki Hirashima , Akio Shiomi , Takuma Oishi , Sumiko Ohnami , Keiichi Ohshima , Kenichi Urakami , Takeshi Nagashima , Ken Yamaguchi

BMP4 and PHLDA1 are plausible drug-targetable candidate genes for KRAS G12A-, G12D-, and G12V-driven colorectal cancer.

Molecular and cellular biochemistry

Avec: Shumpei Ohnami , Kouji Maruyama , Kai Chen , Yu Takahashi , Keiichi Hatakeyama , Keiichi Ohshima , Yuji Shimoda , Ai Sakai , Fukumi Kamada , Sou Nakatani , Akane Naruoka , Sumiko Ohnami , Masatoshi Kusuhara , Yasuto Akiyama , Hiroyasu Kagawa , Akio Shiomi , Takeshi Nagashima , Kenichi Urakami , Ken Yamaguchi

A Cross-sectional Study of Regret in Cancer Patients After Sharing Test Results for Pathogenic Germline Variants of Hereditary Cancers With Relatives.

Cancer nursing

Avec: Naomi Fukuzaki , Yoshimi Kiyozumi , Satomi Higashigawa , Yasue Horiuchi , Hiroyuki Matsubayashi , Seiichiro Nishimura , Keita Mori , Akifumi Notsu , Izumi Suishu , Sumiko Ohnami , Masatoshi Kusuhara , Ken Yamaguchi , Ardith Z Doorenbos , Yuko Takeda

Genomic landscape of pancreatic cancer in the Japanese version of the Cancer Genome Atlas.

Annals of gastroenterological surgery

Avec: Taisuke Imamura , Ryo Ashida , Keiichi Ohshima , Katsuhiko Uesaka , Teiichi Sugiura , Yukiyasu Okamura , Katsuhisa Ohgi , Sumiko Ohnami , Takeshi Nagashima , Ken Yamaguchi

Evaluation of whole genome sequencing utility in identifying driver alterations in cancer genome.

Scientific reports

Avec: Takeshi Nagashima , Ken Yamaguchi , Kenichi Urakami , Yuji Shimoda , Sumiko Ohnami , Keiichi Ohshima , Tomoe Tanabe , Akane Naruoka , Fukumi Kamada , Masakuni Serizawa , Keiichi Hatakeyama , Shumpei Ohnami , Koji Maruyama , Tohru Mochizuki , Maki Mizuguchi , Akio Shiomi , Yasuhisa Ohde , Etsuro Bando , Teiichi Sugiura , Takashi Mukaigawa , Seiichiro Nishimura , Yasuyuki Hirashima , Koichi Mitsuya , Shusuke Yoshikawa , Yoshio Kiyohara , Yasuhiro Tsubosa , Hirohisa Katagiri , Masashi Niwakawa , Kaoru Takahashi , Hiroya Kashiwagi , Yoshichika Yasunaga , Yuji Ishida , Takashi Sugino , Hirotsugu Kenmotsu , Masanori Terashima , Mitsuru Takahashi , Katsuhiko Uesaka , Yasuto Akiyama

Identification of a neoantigen epitope in a melanoma patient with good response to anti-PD-1 antibody therapy.

Immunology letters

Avec: Chizu Nonomura , Masaki Otsuka , Ryota Kondou , Akira Iizuka , Haruo Miyata , Tadashi Ashizawa , Naoki Sakura , Shusuke Yoshikawa , Yoshio Kiyohara , Keiichi Ohshima , Kenichi Urakami , Takeshi Nagashima , Sumiko Ohnami , Masatoshi Kusuhara , Koichi Mitsuya , Nakamasa Hayashi , Yoko Nakasu , Tohru Mochizuki , Ken Yamaguchi , Yasuto Akiyama

Influence of genetic variants of opioid-related genes on opioid-induced adverse effects in patients with lung cancer: A STROBE-compliant observational study.

Medicine

Avec: Rei Tanaka , Junya Sato , Hiroshi Ishikawa , Tetsu Sato , Michihiro Shino , Yasuhisa Ohde , Tetsumi Sato , Keita Mori , Akifumi Notsu , Sumiko Ohnami , Maki Mizuguchi , Takeshi Nagashima , Ken Yamaguchi

Genomic alterations in two patients with esophageal carcinosarcoma identified by whole genome sequencing: a case report.

Surgical case reports

Avec: Masazumi Inoue , Yasuhiro Tsubosa , Sumiko Ohnami , Kazunori Tokizawa , Shuhei Mayanagi , Keiichi Ohshima , Kenichi Urakami , Shumpei Ohnami , Takeshi Nagashima , Ken Yamaguchi

Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma.

BMC cancer

Avec: Taisuke Imamura , Yukiyasu Okamura , Keiichi Ohshima , Katsuhiko Uesaka , Teiichi Sugiura , Takaaki Ito , Yusuke Yamamoto , Ryo Ashida , Katsuhisa Ohgi , Shimpei Otsuka , Sumiko Ohnami , Takeshi Nagashima , Keiichi Hatakeyama , Takashi Sugino , Kenichi Urakami , Yasuto Akiyama , Ken Yamaguchi

Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring

Cancer research communications

Avec: Keiichi Ohshima , Takeshi Nagashima , Keiichi Fujiya , Keiichi Hatakeyama , Yuko Watanabe , Kimiko Morimoto , Fukumi Kamada , Yuji Shimoda , Sumiko Ohnami , Akane Naruoka , Masakuni Serizawa , Shumpei Ohnami , Hirotsugu Kenmotsu , Akio Shiomi , Yasuhiro Tsubosa , Etsuro Bando , Teiichi Sugiura , Takashi Sugino , Masanori Terashima , Katsuhiko Uesaka , Kenichi Urakami , Yasuto Akiyama , Ken Yamaguchi

Comparative analysis of tumor content estimation methods based on simu- lated tumor samples identified their impact on somatic variant detection in cancer whole genome sequencing.

Biomedical research (Tokyo, Japan)

Avec: Takeshi Nagashima , Kenichi Urakami , Yuji Shimoda , Keiichi Ohshima , Masakuni Serizawa , Keiichi Hatakeyama , Sumiko Ohnami , Shumpei Ohnami , Akane Naruoka , Yasue Horiuchi , Akira Iizuka , Koji Maruyama , Yasuto Akiyama , Ken Yamaguchi

Impact of somatic mutations and transcriptomic alterations on cancer aneuploidy.

Biomedical research (Tokyo, Japan)

Avec: Keiichi Hatakeyama , Takeshi Nagashima , Keiichi Ohshima , Sumiko Ohnami , Shumpei Ohnami , Yuji Shimoda , Akane Naruoka , Koji Maruyama , Akira Iizuka , Tadashi Ashizawa , Hirotsugu Kenmotsu , Tohru Mochizuki , Kenichi Urakami , Yasuto Akiyama , Ken Yamaguchi

Réseau de co-auteurs

Ken Yamaguchi 29 collaborations

Takeshi Nagashima 26 collaborations

Kenichi Urakami 25 collaborations

Keiichi Ohshima 23 collaborations

Yasuto Akiyama 19 collaborations

Shumpei Ohnami 17 collaborations

Keiichi Hatakeyama 17 collaborations

Akane Naruoka 14 collaborations

Yuji Shimoda 13 collaborations

Masatoshi Kusuhara 10 collaborations

Koji Maruyama 9 collaborations

Tohru Mochizuki 9 collaborations

Katsuhiko Uesaka 9 collaborations

Takashi Sugino 9 collaborations

Masakuni Serizawa 9 collaborations

Yasue Horiuchi 9 collaborations

Hirotsugu Kenmotsu 8 collaborations

Akio Shiomi 8 collaborations

Teiichi Sugiura 7 collaborations

Yoshimi Kiyozumi 7 collaborations

Hiroyuki Matsubayashi 7 collaborations

Maki Mizuguchi 7 collaborations

Yasuhiro Tsubosa 6 collaborations

Akira Iizuka 6 collaborations

Fukumi Kamada 6 collaborations

Satomi Higashigawa 6 collaborations

Tadashi Ashizawa 5 collaborations

Yasuhisa Ohde 5 collaborations

Seiichiro Nishimura 5 collaborations

Akifumi Notsu 4 collaborations

Yukiyasu Okamura 4 collaborations

Ryo Ashida 4 collaborations

Katsuhisa Ohgi 4 collaborations

Taisuke Imamura 4 collaborations

Masanori Terashima 4 collaborations

Yasuyuki Hirashima 4 collaborations

Etsuro Bando 3 collaborations

Keiichi Fujiya 3 collaborations

Masato Abe 3 collaborations

Takaaki Ito 3 collaborations

Sou Nakatani 3 collaborations

Yoshio Kiyohara 3 collaborations

Nobuhiro Kado 3 collaborations

Keita Mori 3 collaborations

Shuhei Mayanagi 2 collaborations

Hiroyasu Kagawa 2 collaborations

Yuko Watanabe 2 collaborations

Takuma Ohishi 2 collaborations

Tetsuro Onitsuka 2 collaborations

Mitsuhiro Isaka 2 collaborations

Tomoe Tanabe 2 collaborations

Nakamasa Hayashi 2 collaborations

Hirohisa Katagiri 2 collaborations

Masashi Niwakawa 2 collaborations

Kaoru Takahashi 2 collaborations

Hiroya Kashiwagi 2 collaborations

Yuji Ishida 2 collaborations

Mitsuru Takahashi 2 collaborations

Naomi Fukuzaki 2 collaborations

Izumi Suishu 2 collaborations

Ardith Z Doorenbos 2 collaborations

Yuko Takeda 2 collaborations

Yusuke Yamamoto 2 collaborations

Shimpei Otsuka 2 collaborations

Ai Sakai 2 collaborations

Kouji Maruyama 2 collaborations

Takuma Oishi 2 collaborations

Koichi Mitsuya 2 collaborations

Shusuke Yoshikawa 2 collaborations

Eisuke Booka 1 collaboration

Tomoya Yokota 1 collaboration

Kenjiro Ishii 1 collaboration

Masanori Nakamura 1 collaboration

Goro Nakayama 1 collaboration

Yasuhiro Kodera 1 collaboration

Nobuyuki Ohike 1 collaboration

Tomoko Norose 1 collaboration

Keiko Sasaki 1 collaboration

Koji Muramatsu 1 collaboration

Hiroyuki Ichida 1 collaboration

Yuichi Kawanishi 1 collaboration

Ryutaro Fukumura 1 collaboration

Sachi Moromizato 1 collaboration

Toru Kameya 1 collaboration

Takeshi Kawakami 1 collaboration

Kentaro Yamazaki 1 collaboration

Haruyasu Murakami 1 collaboration

Kenya Matsumura 1 collaboration

Masahiro Nakagawa 1 collaboration

Yuko Kakuda 1 collaboration

Toshiaki Takahashi 1 collaboration

Makoto Arai 1 collaboration

Hidehiko Miyake 1 collaboration

Kai Chen 1 collaboration

Yu Takahashi 1 collaboration

Takashi Mukaigawa 1 collaboration

Yoshichika Yasunaga 1 collaboration

Chizu Nonomura 1 collaboration

Masaki Otsuka 1 collaboration

Ryota Kondou 1 collaboration

Haruo Miyata 1 collaboration

Naoki Sakura 1 collaboration

Yoko Nakasu 1 collaboration

Rei Tanaka 1 collaboration

Junya Sato 1 collaboration

Hiroshi Ishikawa 1 collaboration

Tetsu Sato 1 collaboration

Michihiro Shino 1 collaboration

Tetsumi Sato 1 collaboration

Masazumi Inoue 1 collaboration

Kazunori Tokizawa 1 collaboration

Kimiko Morimoto 1 collaboration