Swapnil C Devarkar

Affiliations

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.

Publications (12)

Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses.

Cell reports

Avec: Swapnil C Devarkar , Michael Vetick , Shravani Balaji , Ivan B Lomakin , Luojia Yang , Danni Jin , Wendy V Gilbert , Sidi Chen , Yong Xiong

Nodal modulator (NOMO) is required to sustain endoplasmic reticulum morphology.

The Journal of biological chemistry

Avec: Catherine Amaya , Christopher J F Cameron , Swapnil C Devarkar , Sebastian J H Seager , Mark B Gerstein , Yong Xiong , Christian Schlieker

RIG-I recognizes metabolite-capped RNAs as signaling ligands.

Nucleic acids research

Avec: Brandon D Schweibenz , Mihai Solotchi , Pranita Hanpude , Swapnil C Devarkar , Smita S Patel

APOBEC3A Loop 1 Is a Determinant for Single-Stranded DNA Binding and Deamination.

Biochemistry

Avec: Samantha J Ziegler , Yingxia Hu , Swapnil C Devarkar , Yong Xiong

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Qi Shen , Sushila Kumari , Chaoyi Xu , Sooin Jang , Jiong Shi , Ryan C Burdick , Lev Levintov , Qiancheng Xiong , Chunxiang Wu , Swapnil C Devarkar , Taoran Tian , Therese N Tripler , Yingxia Hu , Shuai Yuan , Joshua Temple , Qingzhou Feng , C Patrick Lusk , Christopher Aiken , Alan N Engelman , Juan R Perilla , Vinay K Pathak , Chenxiang Lin , Yong Xiong

Visualizing the translation landscape in human cells at high resolution.

bioRxiv : the preprint server for biology

Avec: Wei Zheng , Yuekang Zhang , Jimin Wang , Shuhui Wang , Pengxin Chai , Elizabeth J Bailey , Wangbiao Guo , Swapnil C Devarkar , Shenping Wu , Jianfeng Lin , Kai Zhang , Jun Liu , Ivan B Lomakin , Yong Xiong

Mechanistic basis for the translation inhibition of Cutibacterium acnes by Clindamycin.

The Journal of investigative dermatology

Avec: Ivan B Lomakin , Swapnil C Devarkar , Ayman Grada , Christopher G Bunick

Structures of a mobile intron retroelement poised to attack its structured DNA target.

Science (New York, N.Y.)

Avec: Kevin Chung , Ling Xu , Pengxin Chai , Junhui Peng , Swapnil C Devarkar , Anna Marie Pyle

Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.

Nucleic acids research

Avec: Ivan B Lomakin , Swapnil C Devarkar , Shivali Patel , Ayman Grada , Christopher G Bunick

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.

Molecular cell

Avec: Shuai Yuan , Lei Peng , Jonathan J Park , Yingxia Hu , Swapnil C Devarkar , Matthew B Dong , Qi Shen , Shenping Wu , Sidi Chen , Ivan B Lomakin , Yong Xiong

The intrinsically disordered CARDs-Helicase linker in RIG-I is a molecular gate for RNA proofreading.

The EMBO journal

Avec: Brandon D Schweibenz , Swapnil C Devarkar , Mihai Solotchi , Candice Craig , Jie Zheng , Bruce D Pascal , Samantha Gokhale , Ping Xie , Patrick R Griffin , Smita S Patel

Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution

bioRxiv : the preprint server for biology

Avec: Chunxiang Wu , Megan E Meuser , Juan S Rey , Hamed Meshkin , Rachel Yang , Swapnil Chandrakant Devarkar , Christian Freniere , Jiong Shi , Christopher Aiken , Juan R Perilla , Yong Xiong

Réseau de co-auteurs

Yong Xiong 7 collaborations

Ivan B Lomakin 5 collaborations

Yingxia Hu 3 collaborations

Sidi Chen 2 collaborations

Brandon D Schweibenz 2 collaborations

Mihai Solotchi 2 collaborations

Smita S Patel 2 collaborations

Qi Shen 2 collaborations

Jiong Shi 2 collaborations

Chunxiang Wu 2 collaborations

Shuai Yuan 2 collaborations

Christopher Aiken 2 collaborations

Juan R Perilla 2 collaborations

Pengxin Chai 2 collaborations

Shenping Wu 2 collaborations

Ayman Grada 2 collaborations

Christopher G Bunick 2 collaborations

Michael Vetick 1 collaboration

Shravani Balaji 1 collaboration

Luojia Yang 1 collaboration

Danni Jin 1 collaboration

Wendy V Gilbert 1 collaboration

Catherine Amaya 1 collaboration

Christopher J F Cameron 1 collaboration

Sebastian J H Seager 1 collaboration

Mark B Gerstein 1 collaboration

Christian Schlieker 1 collaboration

Pranita Hanpude 1 collaboration

Samantha J Ziegler 1 collaboration

Sushila Kumari 1 collaboration

Chaoyi Xu 1 collaboration

Sooin Jang 1 collaboration

Ryan C Burdick 1 collaboration

Lev Levintov 1 collaboration

Qiancheng Xiong 1 collaboration

Taoran Tian 1 collaboration

Therese N Tripler 1 collaboration

Joshua Temple 1 collaboration

Qingzhou Feng 1 collaboration

C Patrick Lusk 1 collaboration

Alan N Engelman 1 collaboration

Vinay K Pathak 1 collaboration

Chenxiang Lin 1 collaboration

Wei Zheng 1 collaboration

Yuekang Zhang 1 collaboration

Jimin Wang 1 collaboration

Shuhui Wang 1 collaboration

Elizabeth J Bailey 1 collaboration

Wangbiao Guo 1 collaboration

Jianfeng Lin 1 collaboration

Kai Zhang 1 collaboration

Jun Liu 1 collaboration

Kevin Chung 1 collaboration

Ling Xu 1 collaboration

Junhui Peng 1 collaboration

Anna Marie Pyle 1 collaboration

Shivali Patel 1 collaboration

Lei Peng 1 collaboration

Jonathan J Park 1 collaboration

Matthew B Dong 1 collaboration

Candice Craig 1 collaboration

Jie Zheng 1 collaboration

Bruce D Pascal 1 collaboration

Samantha Gokhale 1 collaboration

Ping Xie 1 collaboration

Patrick R Griffin 1 collaboration

Megan E Meuser 1 collaboration

Juan S Rey 1 collaboration

Hamed Meshkin 1 collaboration

Rachel Yang 1 collaboration

Swapnil Chandrakant Devarkar 1 collaboration

Christian Freniere 1 collaboration