Tim Brend

Affiliations

Leeds Institute of Medical Research at St James's, University of Leeds, Leeds LS9 7TF, UK.

ORCID: 0000-0001-9703-7042

Publications (7)

GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models.

Cancers

Avec: Anke Brüning-Richardson , Gary C Shaw , Daniel Tams , Tim Brend , Hitesh Sanganee , Simon T Barry , Gregory Hamm , Richard J A Goodwin , John G Swales , Henry King , Lynette Steele , Ruth Morton , Anastasia Widyadari , Thomas A Ward , Filomena Esteves , Marjorie Boissinot , Georgia Mavria , Alastair Droop , Sean E Lawler , Susan C Short

HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme.

BMC cancer

Avec: Einthavy Arunachalam , William Rogers , Guy R Simpson , Carla Möller-Levet , Gemma Bolton , Mohammed Ismael , Christopher Smith , Karl Keegen , Izhar Bagwan , Tim Brend , Susan C Short , Bangxing Hong , Yoshihiro Otani , Balveen Kaur , Nicola Annels , Richard Morgan , Hardev Pandha

Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol.

BMJ open

Avec: Mark A Hull , Pei Loo Ow , Sharon Ruddock , Tim Brend , Alexandra F Smith , Helen Marshall , Mingyang Song , Andrew T Chan , Wendy S Garrett , Omer Yilmaz , David A Drew , Fiona Collinson , Andrew J Cockbain , Robert Jones , Paul M Loadman , Peter S Hall , Catherine Moriarty , David A Cairns , Giles J Toogood

EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma.

Oncogene

Avec: Nina Struve , Zev A Binder , Lucy F Stead , Tim Brend , Stephen J Bagley , Claire Faulkner , Leonie Ott , Justus Müller-Goebel , Anna-Sophie Weik , Konstantin Hoffer , Leonie Krug , Thorsten Rieckmann , Lara Bußmann , Marvin Henze , Jennifer J D Morrissette , Kathreena M Kurian , Ulrich Schüller , Cordula Petersen , Kai Rothkamm , Donald M O Rourke , Susan C Short , Malte Kriegs

shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.

The Journal of pathology

Avec: Harry R Haynes , Helen L Scott , Clare L Killick-Cole , Gary Shaw , Tim Brend , Kelly M Hares , Juliana Redondo , Kevin C Kemp , Lorena S Ballesteros , Andrew Herman , Oscar Cordero-Llana , William G Singleton , Francesca Mills , Tom Batstone , Harry Bulstrode , Risto A Kauppinen , Heiko Wurdak , James B Uney , Susan C Short , Alastair Wilkins , Kathreena M Kurian

Cancer cell killing by target antigen engagement with engineered complementary intracellular antibody single domains fused to pro-caspase3.

Scientific reports

Avec: Jennifer S Chambers , Tim Brend , Terence H Rabbitts

Correction: Brüning-Richardson et al. GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models.

Cancers

Avec: Anke Brüning-Richardson , Gary C Shaw , Daniel Tams , Tim Brend , Hitesh Sanganee , Simon T Barry , Gregory Hamm , Richard J A Goodwin , John G Swales , Henry King , Lynette Steele , Ruth Morton , Anastasia Widyadari , Thomas A Ward , Filomena Esteves , Marjorie Boissinot , Georgia Mavria , Alastair Droop , Sean E Lawler , Susan C Short

Réseau de co-auteurs

Susan C Short 5 collaborations

Anke Brüning-Richardson 2 collaborations

Gary C Shaw 2 collaborations

Daniel Tams 2 collaborations

Hitesh Sanganee 2 collaborations

Simon T Barry 2 collaborations

Gregory Hamm 2 collaborations

Richard J A Goodwin 2 collaborations

John G Swales 2 collaborations

Henry King 2 collaborations

Lynette Steele 2 collaborations

Ruth Morton 2 collaborations

Anastasia Widyadari 2 collaborations

Thomas A Ward 2 collaborations

Filomena Esteves 2 collaborations

Marjorie Boissinot 2 collaborations

Georgia Mavria 2 collaborations

Alastair Droop 2 collaborations

Sean E Lawler 2 collaborations

Kathreena M Kurian 2 collaborations

Einthavy Arunachalam 1 collaboration

William Rogers 1 collaboration

Guy R Simpson 1 collaboration

Carla Möller-Levet 1 collaboration

Gemma Bolton 1 collaboration

Mohammed Ismael 1 collaboration

Christopher Smith 1 collaboration

Karl Keegen 1 collaboration

Izhar Bagwan 1 collaboration

Bangxing Hong 1 collaboration

Yoshihiro Otani 1 collaboration

Balveen Kaur 1 collaboration

Nicola Annels 1 collaboration

Richard Morgan 1 collaboration

Hardev Pandha 1 collaboration

Mark A Hull 1 collaboration

Pei Loo Ow 1 collaboration

Sharon Ruddock 1 collaboration

Alexandra F Smith 1 collaboration

Helen Marshall 1 collaboration

Mingyang Song 1 collaboration

Andrew T Chan 1 collaboration

Wendy S Garrett 1 collaboration

Omer Yilmaz 1 collaboration

David A Drew 1 collaboration

Fiona Collinson 1 collaboration

Andrew J Cockbain 1 collaboration

Robert Jones 1 collaboration

Paul M Loadman 1 collaboration

Peter S Hall 1 collaboration

Catherine Moriarty 1 collaboration

David A Cairns 1 collaboration

Giles J Toogood 1 collaboration

Nina Struve 1 collaboration

Zev A Binder 1 collaboration

Lucy F Stead 1 collaboration

Stephen J Bagley 1 collaboration

Claire Faulkner 1 collaboration

Leonie Ott 1 collaboration

Justus Müller-Goebel 1 collaboration

Anna-Sophie Weik 1 collaboration

Konstantin Hoffer 1 collaboration

Leonie Krug 1 collaboration

Thorsten Rieckmann 1 collaboration

Lara Bußmann 1 collaboration

Marvin Henze 1 collaboration

Jennifer J D Morrissette 1 collaboration

Ulrich Schüller 1 collaboration

Cordula Petersen 1 collaboration

Kai Rothkamm 1 collaboration

Donald M O Rourke 1 collaboration

Malte Kriegs 1 collaboration

Harry R Haynes 1 collaboration

Helen L Scott 1 collaboration

Clare L Killick-Cole 1 collaboration

Gary Shaw 1 collaboration

Kelly M Hares 1 collaboration

Juliana Redondo 1 collaboration

Kevin C Kemp 1 collaboration

Lorena S Ballesteros 1 collaboration

Andrew Herman 1 collaboration

Oscar Cordero-Llana 1 collaboration

William G Singleton 1 collaboration

Francesca Mills 1 collaboration

Tom Batstone 1 collaboration

Harry Bulstrode 1 collaboration

Risto A Kauppinen 1 collaboration

Heiko Wurdak 1 collaboration

James B Uney 1 collaboration

Alastair Wilkins 1 collaboration

Jennifer S Chambers 1 collaboration

Terence H Rabbitts 1 collaboration