Tim Clackson

Affiliations

ARIAD Pharmaceuticals, Inc., Cambridge, Massachusetts, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited.

Publications (3)

Mobocertinib (TAK-788): A Targeted Inhibitor of

Cancer discovery

Avec: Francois Gonzalvez , Sylvie Vincent , Theresa E Baker , Alexandra E Gould , Shuai Li , Scott D Wardwell , Sara Nadworny , Yaoyu Ning , Sen Zhang , Wei-Sheng Huang , Yongbo Hu , Feng Li , Matthew T Greenfield , Stephan G Zech , Biplab Das , Narayana I Narasimhan , Tim Clackson , David Dalgarno , William C Shakespeare , Michael Fitzgerald , Johara Chouitar , Robert J Griffin , Shengwu Liu , Kwok-Kin Wong , Xiaotian Zhu , Victor M Rivera

XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.

Journal for immunotherapy of cancer

Avec: Kurt A Jenkins , Miso Park , Magali Pederzoli-Ribeil , Ugur Eskiocak , Parker Johnson , Wilson Guzman , Megan McLaughlin , Deborah Moore-Lai , Caitlin O'Toole , Zhen Liu , Benjamin Nicholson , Veronica Flesch , Huawei Qiu , Tim Clackson , Ronan C O'Hagan , Ulrich Rodeck , Margaret Karow , Jennifer O'Neil , John C Williams

Discovery of mobocertinib, a potent, oral inhibitor of EGFR exon 20 insertion mutations in non-small cell lung cancer.

Bioorganic & medicinal chemistry letters

Avec: Wei-Sheng Huang , Feng Li , Yongjin Gong , Yun Zhang , Willmen Youngsaye , Yongjin Xu , Xiaotian Zhu , Matthew T Greenfield , Anna Kohlmann , Paul M Taslimi , Angela Toms , Stephan G Zech , Tianjun Zhou , Biplab Das , Hyun G Jang , Meera Tugnait , Yihua E Ye , Francois Gonzalvez , Theresa E Baker , Sara Nadworny , Yaoyu Ning , Scott D Wardwell , Sen Zhang , Alexandra E Gould , Yongbo Hu , Weston Lane , Robert J Skene , Hua Zou , Tim Clackson , Narayana I Narasimhan , Victor M Rivera , David C Dalgarno , William C Shakespeare

Réseau de co-auteurs

Francois Gonzalvez 2 collaborations

Theresa E Baker 2 collaborations

Alexandra E Gould 2 collaborations

Scott D Wardwell 2 collaborations

Sara Nadworny 2 collaborations

Yaoyu Ning 2 collaborations

Sen Zhang 2 collaborations

Wei-Sheng Huang 2 collaborations

Yongbo Hu 2 collaborations

Feng Li 2 collaborations

Matthew T Greenfield 2 collaborations

Stephan G Zech 2 collaborations

Biplab Das 2 collaborations

Narayana I Narasimhan 2 collaborations

William C Shakespeare 2 collaborations

Xiaotian Zhu 2 collaborations

Victor M Rivera 2 collaborations

Sylvie Vincent 1 collaboration

Shuai Li 1 collaboration

David Dalgarno 1 collaboration

Michael Fitzgerald 1 collaboration

Johara Chouitar 1 collaboration

Robert J Griffin 1 collaboration

Shengwu Liu 1 collaboration

Kwok-Kin Wong 1 collaboration

Kurt A Jenkins 1 collaboration

Miso Park 1 collaboration

Magali Pederzoli-Ribeil 1 collaboration

Ugur Eskiocak 1 collaboration

Parker Johnson 1 collaboration

Wilson Guzman 1 collaboration

Megan McLaughlin 1 collaboration

Deborah Moore-Lai 1 collaboration

Caitlin O'Toole 1 collaboration

Zhen Liu 1 collaboration

Benjamin Nicholson 1 collaboration

Veronica Flesch 1 collaboration

Huawei Qiu 1 collaboration

Ronan C O'Hagan 1 collaboration

Ulrich Rodeck 1 collaboration

Margaret Karow 1 collaboration

Jennifer O'Neil 1 collaboration

John C Williams 1 collaboration

Yongjin Gong 1 collaboration

Yun Zhang 1 collaboration

Willmen Youngsaye 1 collaboration

Yongjin Xu 1 collaboration

Anna Kohlmann 1 collaboration

Paul M Taslimi 1 collaboration

Angela Toms 1 collaboration

Tianjun Zhou 1 collaboration

Hyun G Jang 1 collaboration

Meera Tugnait 1 collaboration

Yihua E Ye 1 collaboration

Weston Lane 1 collaboration

Robert J Skene 1 collaboration

Hua Zou 1 collaboration

David C Dalgarno 1 collaboration