Tom Hofste

Affiliations

Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.

Publications (10)

Presence of Genetic Variants Among Young Men With Severe COVID-19.

JAMA

Avec: Caspar I van der Made , Annet Simons , Janneke Schuurs-Hoeijmakers , Guus van den Heuvel , Tuomo Mantere , Simone Kersten , Rosanne C van Deuren , Marloes Steehouwer , Simon V van Reijmersdal , Martin Jaeger , Tom Hofste , Galuh Astuti , Jordi Corominas Galbany , Vyne van der Schoot , Hans van der Hoeven , Wanda Hagmolen Of Ten Have , Eva Klijn , Catrien van den Meer , Jeroen Fiddelaers , Quirijn de Mast , Chantal P Bleeker-Rovers , Leo A B Joosten , Helger G Yntema , Christian Gilissen , Marcel Nelen , Jos W M van der Meer , Han G Brunner , Mihai G Netea , Frank L van de Veerdonk , Alexander Hoischen

All-in-one whole exome sequencing strategy with simultaneous copy number variant, single nucleotide variant and absence-of-heterozygosity analysis in fetuses with structural ultrasound anomalies: A 1-year experience.

Prenatal diagnosis

Avec: Brigitte H W Faas , Dineke Westra , Sonja A de Munnik , Maartje van Rij , Carlo Marcelis , Sara Joosten , Ingrid Krapels , Vivian Vernimmen , Malou Heijligers , Marjolein H Willemsen , Nicole de Leeuw , Tuula Rinne , Rolph Pfundt , Sanne P Smeekens , Sander P A Stegmann , Merryn Macville , Esther Sikkel , Audrey Coumans , Lia Wijnberger , Irma Derks , Josefa van Lent-Albrechts , Tom Hofste , Raoul Timmermans , Janneke van den End , Servi J C Stevens , Ilse Feenstra

Early On-treatment Circulating Tumor DNA Measurements and Response to Immune Checkpoint Inhibitors in Advanced Urothelial Cancer.

European urology oncology

Avec: Sofie H Tolmeijer , Sandra van Wilpe , Maartje J Geerlings , Daniel von Rhein , Tineke J Smilde , Iris S H Kloots , Harm Westdorp , Mustafa Coskuntürk , Irma M Oving , Jolique A van Ipenburg , Antoine G van der Heijden , Tom Hofste , Marjan M Weiss , Jack A Schalken , Winald R Gerritsen , Marjolijn J L Ligtenberg , Niven Mehra

Reanalysis of exome negative patients with rare disease: a pragmatic workflow for diagnostic applications.

Genome medicine

Avec: Gaby Schobers , Jolanda H Schieving , Helger G Yntema , Maartje Pennings , Rolph Pfundt , Ronny Derks , Tom Hofste , Ilse de Wijs , Nienke Wieskamp , Simone van den Heuvel , Jordi Corominas Galbany , Christian Gilissen , Marcel Nelen , Han G Brunner , Tjitske Kleefstra , Erik-Jan Kamsteeg , Michèl A A P Willemsen , Lisenka E L M Vissers

Genomic instability in non-breast/ovarian malignancies of individuals with germline pathogenic variants in BRCA1/2.

Journal of the National Cancer Institute

Avec: Lisa Elze , Rachel S van der Post , Janet R Vos , Arjen R Mensenkamp , Samhita Pamidimarri Naga , Juliet E Hampstead , Emma Vermeulen , Michiel Oorsprong , Tom Hofste , Michiel Simons , Iris D Nagtegaal , Nicoline Hoogerbrugge , Richarda M de Voer , Marjolijn J L Ligtenberg

Genome sequencing as a generic diagnostic strategy for rare disease.

Genome medicine

Avec: Gaby Schobers , Ronny Derks , Amber den Ouden , Hilde Swinkels , Jeroen van Reeuwijk , Ermanno Bosgoed , Dorien Lugtenberg , Su Ming Sun , Jordi Corominas Galbany , Marjan Weiss , Marinus J Blok , Richelle A C M Olde Keizer , Tom Hofste , Debby Hellebrekers , Nicole de Leeuw , Alexander Stegmann , Erik-Jan Kamsteeg , Aimee D C Paulussen , Marjolijn J L Ligtenberg , Xiangqun Zheng Bradley , John Peden , Alejandra Gutierrez , Adam Pullen , Tom Payne , Christian Gilissen , Arthur van den Wijngaard , Han G Brunner , Marcel Nelen , Helger G Yntema , Lisenka E L M Vissers

Circulating Tumor DNA-Based Disease Monitoring of Patients with Locally Advanced Esophageal Cancer.

Cancers

Avec: Lisa S M Hofste , Maartje J Geerlings , Daniel von Rhein , Sofie H Tolmeijer , Marjan M Weiss , Christian Gilissen , Tom Hofste , Linda M Garms , Marcel J R Janssen , Heidi Rütten , Camiel Rosman , Rachel S van der Post , Bastiaan R Klarenbeek , Marjolijn J L Ligtenberg

Twist exome capture allows for lower average sequence coverage in clinical exome sequencing.

Human genomics

Avec: Burcu Yaldiz , Erdi Kucuk , Juliet Hampstead , Tom Hofste , Rolph Pfundt , Jordi Corominas Galbany , Tuula Rinne , Helger G Yntema , Alexander Hoischen , Marcel Nelen , Christian Gilissen , Auteur inconnu

Circulating tumor DNA detection after neoadjuvant treatment and surgery predicts recurrence in patients with early-stage and locally advanced rectal cancer.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Avec: Lisa S M Hofste , Maartje J Geerlings , Daniel von Rhein , Heidi Rütten , A Helen Westenberg , Marjan M Weiss , Christian Gilissen , Tom Hofste , Rachel S van der Post , Bastiaan R Klarenbeek , Johannes H W de Wilt , Marjolijn J L Ligtenberg , Auteur inconnu

Innovative all-in-one exome sequencing strategy for diagnostic genetic testing in male infertility: Validation and 10-month experience.

Andrology

Avec: Manon S Oud , Nicole de Leeuw , Dominique F C M Smeets , Liliana Ramos , Godfried W van der Heijden , Raoul G J Timmermans , Maartje van de Vorst , Tom Hofste , Marlies J E Kempers , Marijn F Stokman , Kathleen W M D'Hauwers , Brigitte H W Faas , Dineke Westra

Réseau de co-auteurs

Christian Gilissen 6 collaborations

Marjolijn J L Ligtenberg 5 collaborations

Jordi Corominas Galbany 4 collaborations

Helger G Yntema 4 collaborations

Marcel Nelen 4 collaborations

Han G Brunner 3 collaborations

Nicole de Leeuw 3 collaborations

Rolph Pfundt 3 collaborations

Maartje J Geerlings 3 collaborations

Daniel von Rhein 3 collaborations

Marjan M Weiss 3 collaborations

Rachel S van der Post 3 collaborations

Alexander Hoischen 2 collaborations

Brigitte H W Faas 2 collaborations

Dineke Westra 2 collaborations

Tuula Rinne 2 collaborations

Sofie H Tolmeijer 2 collaborations

Gaby Schobers 2 collaborations

Ronny Derks 2 collaborations

Erik-Jan Kamsteeg 2 collaborations

Lisenka E L M Vissers 2 collaborations

Lisa S M Hofste 2 collaborations

Heidi Rütten 2 collaborations

Bastiaan R Klarenbeek 2 collaborations

None None 2 collaborations

Caspar I van der Made 1 collaboration

Annet Simons 1 collaboration

Janneke Schuurs-Hoeijmakers 1 collaboration

Guus van den Heuvel 1 collaboration

Tuomo Mantere 1 collaboration

Simone Kersten 1 collaboration

Rosanne C van Deuren 1 collaboration

Marloes Steehouwer 1 collaboration

Simon V van Reijmersdal 1 collaboration

Martin Jaeger 1 collaboration

Galuh Astuti 1 collaboration

Vyne van der Schoot 1 collaboration

Hans van der Hoeven 1 collaboration

Wanda Hagmolen Of Ten Have 1 collaboration

Eva Klijn 1 collaboration

Catrien van den Meer 1 collaboration

Jeroen Fiddelaers 1 collaboration

Quirijn de Mast 1 collaboration

Chantal P Bleeker-Rovers 1 collaboration

Leo A B Joosten 1 collaboration

Jos W M van der Meer 1 collaboration

Mihai G Netea 1 collaboration

Frank L van de Veerdonk 1 collaboration

Sonja A de Munnik 1 collaboration

Maartje van Rij 1 collaboration

Carlo Marcelis 1 collaboration

Sara Joosten 1 collaboration

Ingrid Krapels 1 collaboration

Vivian Vernimmen 1 collaboration

Malou Heijligers 1 collaboration

Marjolein H Willemsen 1 collaboration

Sanne P Smeekens 1 collaboration

Sander P A Stegmann 1 collaboration

Merryn Macville 1 collaboration

Esther Sikkel 1 collaboration

Audrey Coumans 1 collaboration

Lia Wijnberger 1 collaboration

Irma Derks 1 collaboration

Josefa van Lent-Albrechts 1 collaboration

Raoul Timmermans 1 collaboration

Janneke van den End 1 collaboration

Servi J C Stevens 1 collaboration

Ilse Feenstra 1 collaboration

Sandra van Wilpe 1 collaboration

Tineke J Smilde 1 collaboration

Iris S H Kloots 1 collaboration

Harm Westdorp 1 collaboration

Mustafa Coskuntürk 1 collaboration

Irma M Oving 1 collaboration

Jolique A van Ipenburg 1 collaboration

Antoine G van der Heijden 1 collaboration

Jack A Schalken 1 collaboration

Winald R Gerritsen 1 collaboration

Niven Mehra 1 collaboration

Jolanda H Schieving 1 collaboration

Maartje Pennings 1 collaboration

Ilse de Wijs 1 collaboration

Nienke Wieskamp 1 collaboration

Simone van den Heuvel 1 collaboration

Tjitske Kleefstra 1 collaboration

Michèl A A P Willemsen 1 collaboration

Lisa Elze 1 collaboration

Janet R Vos 1 collaboration

Arjen R Mensenkamp 1 collaboration

Samhita Pamidimarri Naga 1 collaboration

Juliet E Hampstead 1 collaboration

Emma Vermeulen 1 collaboration

Michiel Oorsprong 1 collaboration

Michiel Simons 1 collaboration

Iris D Nagtegaal 1 collaboration

Nicoline Hoogerbrugge 1 collaboration

Richarda M de Voer 1 collaboration

Amber den Ouden 1 collaboration

Hilde Swinkels 1 collaboration

Jeroen van Reeuwijk 1 collaboration

Ermanno Bosgoed 1 collaboration

Dorien Lugtenberg 1 collaboration

Su Ming Sun 1 collaboration

Marjan Weiss 1 collaboration

Marinus J Blok 1 collaboration

Richelle A C M Olde Keizer 1 collaboration

Debby Hellebrekers 1 collaboration

Alexander Stegmann 1 collaboration

Aimee D C Paulussen 1 collaboration

Xiangqun Zheng Bradley 1 collaboration

John Peden 1 collaboration

Alejandra Gutierrez 1 collaboration

Adam Pullen 1 collaboration

Tom Payne 1 collaboration

Arthur van den Wijngaard 1 collaboration

Linda M Garms 1 collaboration

Marcel J R Janssen 1 collaboration

Camiel Rosman 1 collaboration

Burcu Yaldiz 1 collaboration

Erdi Kucuk 1 collaboration

Juliet Hampstead 1 collaboration

A Helen Westenberg 1 collaboration

Johannes H W de Wilt 1 collaboration

Manon S Oud 1 collaboration

Dominique F C M Smeets 1 collaboration

Liliana Ramos 1 collaboration

Godfried W van der Heijden 1 collaboration

Raoul G J Timmermans 1 collaboration

Maartje van de Vorst 1 collaboration

Marlies J E Kempers 1 collaboration

Marijn F Stokman 1 collaboration

Kathleen W M D'Hauwers 1 collaboration