Wim Mandemakers

Affiliations

Erasmus MC, University Medical Center Rotterdam, Department of Clinical Genetics, P.O. Box 2040, 3000 CA Rotterdam, Netherlands.

ORCID: 0000-0003-2673-5972

Publications (11)

deCLUTTER2+ - a pipeline to analyze calcium traces in a stem cell model for ventral midbrain patterned astrocytes.

Disease models & mechanisms

Avec: Martyna M Grochowska , Federico Ferraro , Ana Carreras Mascaro , Domenico Natale , Amber Winkelaar , Valerie Boumeester , Guido J Breedveld , Vincenzo Bonifati , Wim Mandemakers

WARS2 mutations cause dopa-responsive early-onset parkinsonism and progressive myoclonus ataxia.

Parkinsonism & related disorders

Avec: Matej Skorvanek , Irena Rektorova , Wim Mandemakers , Matias Wagner , Robert Steinfeld , Laura Orec , Vladimir Han , Petra Pavelekova , Alexandra Lackova , Kristina Kulcsarova , Miriam Ostrozovicova , Zuzana Gdovinova , Barbara Plecko , Theresa Brunet , Riccardo Berutti , Demy J S Kuipers , Valerie Boumeester , Petra Havrankova , M A J Tijssen , Rauan Kaiyrzhanov , Mie Rizig , Henry Houlden , Juliane Winkelmann , Vincenzo Bonifati , Michael Zech , Robert Jech

Generation of isogenic control DJ-1-delP GC13 for the genetic Parkinson's disease-patient derived iPSC line DJ-1-delP (LCSBi008-A-1).

Stem cell research

Avec: Pauline Mencke , Zoé Hanss , Javier Jarazo , François Massart , Arkadiusz Rybicki , Elizabet Petkovski , Enrico Glaab , Ibrahim Boussaad , Vincenzo Bonifati , Jens Christian Schwamborn , Wim Mandemakers , Rejko Krüger

LRP10 and α-synuclein transmission in Lewy body diseases.

Cellular and molecular life sciences : CMLS

Avec: Ana Carreras Mascaro , Martyna M Grochowska , Valerie Boumeester , Natasja F J Dits , Ece Naz Bilgiҫ , Guido J Breedveld , Leonie Vergouw , Frank Jan de Jong , Martin E van Royen , Vincenzo Bonifati , Wim Mandemakers

CRISPR/Cas9-mediated LRP10 Knockout in HuTu-80 and HEK 293T Cell Lines.

Bio-protocol

Avec: Martyna M Grochowska , Vincenzo Bonifati , Wim Mandemakers

Parkinson's disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth.

Cell death & disease

Avec: Rongmin Chen , Han-A Park , Nelli Mnatsakanyan , Yulong Niu , Pawel Licznerski , Jing Wu , Paige Miranda , Morven Graham , Jack Tang , Agnita J W Boon , Giovanni Cossu , Wim Mandemakers , Vincenzo Bonifati , Peter J S Smith , Kambiz N Alavian , Elizabeth A Jonas

EIF2AK2 Missense Variants Associated with Early Onset Generalized Dystonia.

Annals of neurology

Avec: Demy J S Kuipers , Wim Mandemakers , Chin-Song Lu , Simone Olgiati , Guido J Breedveld , Christina Fevga , Vera Tadic , Miryam Carecchio , Bradley Osterman , Lena Sagi-Dain , Yah-Huei Wu-Chou , Chiung C Chen , Hsiu-Chen Chang , Shey-Lin Wu , Tu-Hsueh Yeh , Yi-Hsin Weng , Antonio E Elia , Celeste Panteghini , Nicolas Marotta , Martje G Pauly , Andrea A Kühn , Jens Volkmann , Baiba Lace , Inge A Meijer , Krishna Kandaswamy , Marialuisa Quadri , Barbara Garavaglia , Katja Lohmann , Peter Bauer , Niccolò E Mencacci , Steven J Lubbe , Christine Klein , Aida M Bertoli-Avella , Vincenzo Bonifati

LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson's disease and dementia with Lewy bodies.

Acta neuropathologica

Avec: Martyna M Grochowska , Ana Carreras Mascaro , Valerie Boumeester , Domenico Natale , Guido J Breedveld , Hanneke Geut , Wiggert A van Cappellen , Agnita J W Boon , Anneke J A Kievit , Esther Sammler , Auteur inconnu , Piero Parchi , Pietro Cortelli , Dario R Alessi , Wilma D J van de Berg , Vincenzo Bonifati , Wim Mandemakers

Correcting Differential Gene Expression Analysis for Cyto-Architectural Alterations in Substantia Nigra of Parkinson's Disease Patients Reveals Known and Potential Novel Disease-Associated Genes and Pathways.

Cells

Avec: Federico Ferraro , Christina Fevga , Vincenzo Bonifati , Wim Mandemakers , Ahmed Mahfouz , Marcel Reinders

Generation and characterization of a genetic Parkinson's disease-patient derived iPSC line DJ-1-delP (LCSBi008-A).

Stem cell research

Avec: Pauline Mencke , Ibrahim Boussaad , Gizem Önal , Anneke J A Kievit , Agnita J W Boon , Wim Mandemakers , Vincenzo Bonifati , Rejko Krüger

PTPA variants and impaired PP2A activity in early-onset parkinsonism with intellectual disability.

Brain : a journal of neurology

Avec: Christina Fevga , Christelle Tesson , Ana Carreras Mascaro , Thomas Courtin , Riaan van Coller , Salma Sakka , Federico Ferraro , Nouha Farhat , Soraya Bardien , Mariem Damak , Jonathan Carr , Mélanie Ferrien , Valerie Boumeester , Jasmijn Hundscheid , Nicola Grillenzoni , Irini A Kessissoglou , Demy J S Kuipers , Marialuisa Quadri , Auteur inconnu , Auteur inconnu , Jean-Christophe Corvol , Chokri Mhiri , Bassem A Hassan , Guido J Breedveld , Suzanne Lesage , Wim Mandemakers , Alexis Brice , Vincenzo Bonifati

Réseau de co-auteurs

Vincenzo Bonifati 11 collaborations

Valerie Boumeester 5 collaborations

Guido J Breedveld 5 collaborations

Martyna M Grochowska 4 collaborations

Ana Carreras Mascaro 4 collaborations

Federico Ferraro 3 collaborations

Demy J S Kuipers 3 collaborations

Agnita J W Boon 3 collaborations

Christina Fevga 3 collaborations

None None 3 collaborations

Domenico Natale 2 collaborations

Pauline Mencke 2 collaborations

Ibrahim Boussaad 2 collaborations

Rejko Krüger 2 collaborations

Marialuisa Quadri 2 collaborations

Anneke J A Kievit 2 collaborations

Amber Winkelaar 1 collaboration

Matej Skorvanek 1 collaboration

Irena Rektorova 1 collaboration

Matias Wagner 1 collaboration

Robert Steinfeld 1 collaboration

Laura Orec 1 collaboration

Vladimir Han 1 collaboration

Petra Pavelekova 1 collaboration

Alexandra Lackova 1 collaboration

Kristina Kulcsarova 1 collaboration

Miriam Ostrozovicova 1 collaboration

Zuzana Gdovinova 1 collaboration

Barbara Plecko 1 collaboration

Theresa Brunet 1 collaboration

Riccardo Berutti 1 collaboration

Petra Havrankova 1 collaboration

M A J Tijssen 1 collaboration

Rauan Kaiyrzhanov 1 collaboration

Mie Rizig 1 collaboration

Henry Houlden 1 collaboration

Juliane Winkelmann 1 collaboration

Michael Zech 1 collaboration

Robert Jech 1 collaboration

Zoé Hanss 1 collaboration

Javier Jarazo 1 collaboration

François Massart 1 collaboration

Arkadiusz Rybicki 1 collaboration

Elizabet Petkovski 1 collaboration

Enrico Glaab 1 collaboration

Jens Christian Schwamborn 1 collaboration

Natasja F J Dits 1 collaboration

Ece Naz Bilgiҫ 1 collaboration

Leonie Vergouw 1 collaboration

Frank Jan de Jong 1 collaboration

Martin E van Royen 1 collaboration

Rongmin Chen 1 collaboration

Han-A Park 1 collaboration

Nelli Mnatsakanyan 1 collaboration

Yulong Niu 1 collaboration

Pawel Licznerski 1 collaboration

Jing Wu 1 collaboration

Paige Miranda 1 collaboration

Morven Graham 1 collaboration

Jack Tang 1 collaboration

Giovanni Cossu 1 collaboration

Peter J S Smith 1 collaboration

Kambiz N Alavian 1 collaboration

Elizabeth A Jonas 1 collaboration

Chin-Song Lu 1 collaboration

Simone Olgiati 1 collaboration

Vera Tadic 1 collaboration

Miryam Carecchio 1 collaboration

Bradley Osterman 1 collaboration

Lena Sagi-Dain 1 collaboration

Yah-Huei Wu-Chou 1 collaboration

Chiung C Chen 1 collaboration

Hsiu-Chen Chang 1 collaboration

Shey-Lin Wu 1 collaboration

Tu-Hsueh Yeh 1 collaboration

Yi-Hsin Weng 1 collaboration

Antonio E Elia 1 collaboration

Celeste Panteghini 1 collaboration

Nicolas Marotta 1 collaboration

Martje G Pauly 1 collaboration

Andrea A Kühn 1 collaboration

Jens Volkmann 1 collaboration

Baiba Lace 1 collaboration

Inge A Meijer 1 collaboration

Krishna Kandaswamy 1 collaboration

Barbara Garavaglia 1 collaboration

Katja Lohmann 1 collaboration

Peter Bauer 1 collaboration

Niccolò E Mencacci 1 collaboration

Steven J Lubbe 1 collaboration

Christine Klein 1 collaboration

Aida M Bertoli-Avella 1 collaboration

Hanneke Geut 1 collaboration

Wiggert A van Cappellen 1 collaboration

Esther Sammler 1 collaboration

Piero Parchi 1 collaboration

Pietro Cortelli 1 collaboration

Dario R Alessi 1 collaboration

Wilma D J van de Berg 1 collaboration

Ahmed Mahfouz 1 collaboration

Marcel Reinders 1 collaboration

Gizem Önal 1 collaboration

Christelle Tesson 1 collaboration

Thomas Courtin 1 collaboration

Riaan van Coller 1 collaboration

Salma Sakka 1 collaboration

Nouha Farhat 1 collaboration

Soraya Bardien 1 collaboration

Mariem Damak 1 collaboration

Jonathan Carr 1 collaboration

Mélanie Ferrien 1 collaboration

Jasmijn Hundscheid 1 collaboration

Nicola Grillenzoni 1 collaboration

Irini A Kessissoglou 1 collaboration

Jean-Christophe Corvol 1 collaboration

Chokri Mhiri 1 collaboration

Bassem A Hassan 1 collaboration

Suzanne Lesage 1 collaboration

Alexis Brice 1 collaboration