Youcef Mehellou

Affiliations
  • School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.
ORCID: 0000-0001-5720-8513

Publications (13)

Generation of Stable Isopentenyl Monophosphate Aryloxy Triester Phosphoramidates as Activators of Vγ9Vδ2 T Cells.

ChemMedChem
Avec: Qin Xu , Taher E Taher , Elizabeth Ashby , Maria Sharif , Benjamin E Willcox , Youcef Mehellou

Aryloxy Triester Phosphoramidates as Phosphoserine Prodrugs: A Proof of Concept Study.

ChemMedChem
Avec: Ageo Miccoli , Binar A Dhiani , Peter J Thornton , Olivia A Lambourne , Edward James , Hachemi Kadri , Youcef Mehellou

SPAK and OSR1 kinases bind and phosphorylate the β

Biochemical and biophysical research communications
Avec: Abdulrahman Elzwawi , Gillian Grafton , Nicholas M Barnes , Youcef Mehellou

Sequence specific assignment and determination of OSR1 C-terminal domain structure by NMR.

Biochemical and biophysical research communications
Avec: Mubarak A AlAmri , Mark Jeeves , Youcef Mehellou

PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage.

Journal of medicinal chemistry
Avec: Olivia A Lambourne , Shane Bell , Léa P Wilhelm , Erika B Yarbrough , Gabriel G Holly , Oliver M Russell , Arwa M Alghamdi , Azeza M Fdel , Carmine Varricchio , Emma L Lane , Ian G Ganley , Arwyn T Jones , Matthew S Goldberg , Youcef Mehellou

The ProTide Prodrug Technology: Where Next?

ACS medicinal chemistry letters
Avec: Ashwag S Alanazi , Edward James , Youcef Mehellou

Parkinson's Disease: Are PINK1 Activators Inching Closer to the Clinic?

ACS medicinal chemistry letters
Avec: Youcef Mehellou

Phosphonodiamidate prodrugs of phosphoantigens (ProPAgens) exhibit potent Vγ9/Vδ2 T cell activation and eradication of cancer cells.

RSC medicinal chemistry
Avec: Qin Xu , Maria Sharif , Edward James , Jack O Dismorr , James H R Tucker , Benjamin E Willcox , Youcef Mehellou

Phosphotyrosine prodrugs: design, synthesis and anti-STAT3 activity of ISS-610 aryloxy triester phosphoramidate prodrugs.

MedChemComm
Avec: Ageo Miccoli , Binar A Dhiani , Youcef Mehellou

The Cul4-DDB1-WDR3/WDR6 Complex Binds SPAK and OSR1 Kinases in a Phosphorylation-Dependent Manner.

Chembiochem : a European journal of chemical biology
Avec: Binar A Dhiani , Youcef Mehellou

Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses.

Journal of medicinal chemistry
Avec: Hachemi Kadri , Taher E Taher , Qin Xu , Maria Sharif , Elizabeth Ashby , Richard T Bryan , Benjamin E Willcox , Youcef Mehellou

Aryloxy Pivaloyloxymethyl Prodrugs as Nucleoside Monophosphate Prodrugs.

Journal of medicinal chemistry
Avec: Ashwag S Alanazi , Ageo Miccoli , Youcef Mehellou

Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains.

Chembiochem : a European journal of chemical biology
Avec: Karen T Elvers , Magdalena Lipka-Lloyd , Rebecca C Trueman , Benjamin D Bax , Youcef Mehellou

Réseau de co-auteurs

Qin Xu 3 collaborations
Maria Sharif 3 collaborations
Benjamin E Willcox 3 collaborations
Ageo Miccoli 3 collaborations
Binar A Dhiani 3 collaborations
Edward James 3 collaborations
Taher E Taher 2 collaborations
Elizabeth Ashby 2 collaborations
Olivia A Lambourne 2 collaborations
Hachemi Kadri 2 collaborations
Ashwag S Alanazi 2 collaborations
Peter J Thornton 1 collaboration
Abdulrahman Elzwawi 1 collaboration
Gillian Grafton 1 collaboration
Nicholas M Barnes 1 collaboration
Mubarak A AlAmri 1 collaboration
Mark Jeeves 1 collaboration
Shane Bell 1 collaboration
Léa P Wilhelm 1 collaboration
Erika B Yarbrough 1 collaboration
Gabriel G Holly 1 collaboration
Oliver M Russell 1 collaboration
Arwa M Alghamdi 1 collaboration
Azeza M Fdel 1 collaboration
Carmine Varricchio 1 collaboration
Emma L Lane 1 collaboration
Ian G Ganley 1 collaboration
Arwyn T Jones 1 collaboration
Matthew S Goldberg 1 collaboration
Jack O Dismorr 1 collaboration
James H R Tucker 1 collaboration
Richard T Bryan 1 collaboration
Karen T Elvers 1 collaboration
Magdalena Lipka-Lloyd 1 collaboration
Rebecca C Trueman 1 collaboration
Benjamin D Bax 1 collaboration