Titre : Protéogénomique

Protéogénomique : Questions médicales fréquentes

Termes MeSH sélectionnés :

Correlation of Data
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Protéogénomique : Questions médicales les plus fréquentes", "headline": "Protéogénomique : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Protéogénomique : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-01", "dateModified": "2025-03-28", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Protéogénomique" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Protéomique", "url": "https://questionsmedicales.fr/mesh/D040901", "about": { "@type": "MedicalCondition", "name": "Protéomique", "code": { "@type": "MedicalCode", "code": "D040901", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "H01.181.122.738" } } }, "about": { "@type": "MedicalCondition", "name": "Protéogénomique", "alternateName": "Proteogenomics", "code": { "@type": "MedicalCode", "code": "D000071696", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Bing Zhang", "url": "https://questionsmedicales.fr/author/Bing%20Zhang", "affiliation": { "@type": "Organization", "name": "Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: bing.zhang@bcm.edu." } }, { "@type": "Person", "name": "Pei Wang", "url": "https://questionsmedicales.fr/author/Pei%20Wang", "affiliation": { "@type": "Organization", "name": "Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA." } }, { "@type": "Person", "name": "Li Ding", "url": "https://questionsmedicales.fr/author/Li%20Ding", "affiliation": { "@type": "Organization", "name": "Department of Medicine and Genetics, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63108, USA. Electronic address: lding@wustl.edu." } }, { "@type": "Person", "name": "Bo Wen", "url": "https://questionsmedicales.fr/author/Bo%20Wen", "affiliation": { "@type": "Organization", "name": "Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA." } }, { "@type": "Person", "name": "Ana I Robles", "url": "https://questionsmedicales.fr/author/Ana%20I%20Robles", "affiliation": { "@type": "Organization", "name": "Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD 20892, USA." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Correlation Study Between Bone Cement Distribution and Adjacent Vertebral Fractures After Percutaneous Vertebroplasty.", "datePublished": "2023-08-09", "url": "https://questionsmedicales.fr/article/37562680", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.wneu.2023.08.008" } }, { "@type": "ScholarlyArticle", "name": "Critical thinking among institutional academic advisors and sociodemographic, professional and academic variables: A multicenter correlation study.", "datePublished": "2023-07-11", "url": "https://questionsmedicales.fr/article/37478586", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.nepr.2023.103713" } }, { "@type": "ScholarlyArticle", "name": "Curvilinear relationship between burnout and work engagement among staff in community services for the elderly: A correlation study.", "datePublished": "2022-07-22", "url": "https://questionsmedicales.fr/article/35937238", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3389/fpubh.2022.939649" } }, { "@type": "ScholarlyArticle", "name": "Correlation study of malignant lymphoma and breast Cancer in different gender European populations: mendelian randomization analysis.", "datePublished": "2023-10-09", "url": "https://questionsmedicales.fr/article/37814219", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1186/s12863-023-01162-1" } }, { "@type": "ScholarlyArticle", "name": "Work alienation influences nurses' readiness for professional development and willingness to learn: A cross-sectional correlation study.", "datePublished": "2023-05-09", "url": "https://questionsmedicales.fr/article/37159456", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1371/journal.pone.0284963" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Disciplines des sciences naturelles", "item": "https://questionsmedicales.fr/mesh/D010811" }, { "@type": "ListItem", "position": 3, "name": "Chimie", "item": "https://questionsmedicales.fr/mesh/D002621" }, { "@type": "ListItem", "position": 4, "name": "Biochimie", "item": "https://questionsmedicales.fr/mesh/D001671" }, { "@type": "ListItem", "position": 5, "name": "Protéomique", "item": "https://questionsmedicales.fr/mesh/D040901" }, { "@type": "ListItem", "position": 6, "name": "Protéogénomique", "item": "https://questionsmedicales.fr/mesh/D000071696" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Protéogénomique - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Protéogénomique", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-14", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Protéogénomique", "description": "Comment la protéogénomique aide-t-elle au diagnostic des maladies ?\nQuels tests sont utilisés en protéogénomique ?\nLa protéogénomique peut-elle détecter des cancers ?\nQuels échantillons sont analysés en protéogénomique ?\nLa protéogénomique est-elle utilisée en médecine personnalisée ?", "url": "https://questionsmedicales.fr/mesh/D000071696?mesh_terms=Correlation+of+Data&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Protéogénomique", "description": "Quels symptômes peuvent être liés à des anomalies protéiques ?\nLes maladies auto-immunes sont-elles étudiées en protéogénomique ?\nComment les protéines affectent-elles les symptômes ?\nLes symptômes de maladies métaboliques sont-ils liés à la protéogénomique ?\nPeut-on prédire des symptômes grâce à la protéogénomique ?", "url": "https://questionsmedicales.fr/mesh/D000071696?mesh_terms=Correlation+of+Data&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Protéogénomique", "description": "La protéogénomique peut-elle aider à la prévention des maladies ?\nQuels facteurs de risque sont identifiés par la protéogénomique ?\nComment la protéogénomique influence-t-elle les programmes de dépistage ?\nPeut-on prévenir des maladies grâce à des interventions protéogénomiques ?\nLa nutrition peut-elle être influencée par la protéogénomique ?", "url": "https://questionsmedicales.fr/mesh/D000071696?mesh_terms=Correlation+of+Data&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Protéogénomique", "description": "La protéogénomique influence-t-elle les traitements ?\nQuels types de traitements sont développés grâce à la protéogénomique ?\nLa protéogénomique aide-t-elle à la résistance aux médicaments ?\nLes traitements peuvent-ils être personnalisés grâce à la protéogénomique ?\nQuels médicaments sont influencés par la protéogénomique ?", "url": "https://questionsmedicales.fr/mesh/D000071696?mesh_terms=Correlation+of+Data&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Protéogénomique", "description": "Quelles complications peuvent survenir en cas d'anomalies protéiques ?\nLes maladies cardiovasculaires sont-elles liées à la protéogénomique ?\nComment la protéogénomique aide-t-elle à comprendre les complications ?\nLes complications liées à la protéogénomique sont-elles évitables ?\nPeut-on prédire des complications grâce à la protéogénomique ?", "url": "https://questionsmedicales.fr/mesh/D000071696?mesh_terms=Correlation+of+Data&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Protéogénomique", "description": "Quels sont les principaux facteurs de risque identifiés par la protéogénomique ?\nLa protéogénomique peut-elle identifier des risques environnementaux ?\nLes habitudes de vie influencent-elles les facteurs de risque protéogénomiques ?\nComment la génétique influence-t-elle les facteurs de risque ?\nPeut-on modifier les facteurs de risque grâce à la protéogénomique ?", "url": "https://questionsmedicales.fr/mesh/D000071696?mesh_terms=Correlation+of+Data&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment la protéogénomique aide-t-elle au diagnostic des maladies ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet d'identifier des biomarqueurs protéiques spécifiques pour un diagnostic plus précis." } }, { "@type": "Question", "name": "Quels tests sont utilisés en protéogénomique ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des techniques comme la spectrométrie de masse et l'électrophorèse sont couramment utilisées." } }, { "@type": "Question", "name": "La protéogénomique peut-elle détecter des cancers ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle aide à identifier des protéines spécifiques associées à différents types de cancers." } }, { "@type": "Question", "name": "Quels échantillons sont analysés en protéogénomique ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des échantillons de tissus, de sang ou de fluides biologiques sont souvent analysés." } }, { "@type": "Question", "name": "La protéogénomique est-elle utilisée en médecine personnalisée ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle permet d'adapter les traitements en fonction du profil protéique du patient." } }, { "@type": "Question", "name": "Quels symptômes peuvent être liés à des anomalies protéiques ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes variés comme la fatigue, la douleur ou des troubles neurologiques peuvent survenir." } }, { "@type": "Question", "name": "Les maladies auto-immunes sont-elles étudiées en protéogénomique ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la protéogénomique aide à comprendre les mécanismes sous-jacents des maladies auto-immunes." } }, { "@type": "Question", "name": "Comment les protéines affectent-elles les symptômes ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Les protéines peuvent influencer des voies biologiques, entraînant divers symptômes cliniques." } }, { "@type": "Question", "name": "Les symptômes de maladies métaboliques sont-ils liés à la protéogénomique ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des déséquilibres protéiques peuvent contribuer à des symptômes de maladies métaboliques." } }, { "@type": "Question", "name": "Peut-on prédire des symptômes grâce à la protéogénomique ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des modèles prédictifs basés sur des profils protéiques peuvent anticiper certains symptômes." } }, { "@type": "Question", "name": "La protéogénomique peut-elle aider à la prévention des maladies ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle permet d'identifier des facteurs de risque protéiques pour des interventions précoces." } }, { "@type": "Question", "name": "Quels facteurs de risque sont identifiés par la protéogénomique ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs comme des niveaux anormaux de certaines protéines peuvent indiquer un risque accru." } }, { "@type": "Question", "name": "Comment la protéogénomique influence-t-elle les programmes de dépistage ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet de cibler des populations à risque pour des dépistages plus efficaces." } }, { "@type": "Question", "name": "Peut-on prévenir des maladies grâce à des interventions protéogénomiques ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des interventions basées sur des profils protéiques peuvent réduire le risque de maladies." } }, { "@type": "Question", "name": "La nutrition peut-elle être influencée par la protéogénomique ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle aide à adapter les régimes alimentaires en fonction des besoins protéiques individuels." } }, { "@type": "Question", "name": "La protéogénomique influence-t-elle les traitements ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle permet de développer des thérapies ciblées basées sur le profil protéique des patients." } }, { "@type": "Question", "name": "Quels types de traitements sont développés grâce à la protéogénomique ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Des traitements biologiques, comme les anticorps monoclonaux, sont souvent développés." } }, { "@type": "Question", "name": "La protéogénomique aide-t-elle à la résistance aux médicaments ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle identifie des mécanismes de résistance, permettant d'ajuster les traitements." } }, { "@type": "Question", "name": "Les traitements peuvent-ils être personnalisés grâce à la protéogénomique ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les traitements peuvent être adaptés en fonction des profils protéiques individuels." } }, { "@type": "Question", "name": "Quels médicaments sont influencés par la protéogénomique ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des médicaments anticancéreux et des immunothérapies sont souvent influencés par cette approche." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir en cas d'anomalies protéiques ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications comme des troubles métaboliques ou des maladies dégénératives peuvent survenir." } }, { "@type": "Question", "name": "Les maladies cardiovasculaires sont-elles liées à la protéogénomique ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des profils protéiques spécifiques peuvent être associés à un risque accru de maladies cardiovasculaires." } }, { "@type": "Question", "name": "Comment la protéogénomique aide-t-elle à comprendre les complications ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet d'analyser les interactions entre gènes et protéines, révélant des mécanismes de complications." } }, { "@type": "Question", "name": "Les complications liées à la protéogénomique sont-elles évitables ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être évitées par des interventions précoces basées sur des analyses protéiques." } }, { "@type": "Question", "name": "Peut-on prédire des complications grâce à la protéogénomique ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des modèles prédictifs basés sur des données protéomiques peuvent anticiper des complications." } }, { "@type": "Question", "name": "Quels sont les principaux facteurs de risque identifiés par la protéogénomique ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs comme l'âge, l'hérédité et des niveaux protéiques anormaux sont souvent identifiés." } }, { "@type": "Question", "name": "La protéogénomique peut-elle identifier des risques environnementaux ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut révéler comment des facteurs environnementaux influencent les profils protéiques." } }, { "@type": "Question", "name": "Les habitudes de vie influencent-elles les facteurs de risque protéogénomiques ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes comme l'alimentation et l'exercice peuvent modifier les niveaux protéiques." } }, { "@type": "Question", "name": "Comment la génétique influence-t-elle les facteurs de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "La génétique détermine la production de certaines protéines, influençant ainsi le risque de maladies." } }, { "@type": "Question", "name": "Peut-on modifier les facteurs de risque grâce à la protéogénomique ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des interventions ciblées peuvent aider à modifier les niveaux protéiques et réduire les risques." } } ] } ] }

Sources (10000 au total)

Correlation Study Between Bone Cement Distribution and Adjacent Vertebral Fractures After Percutaneous Vertebroplasty.

We investigated the correlation between bone cement distribution and adjacent vertebral fractures (AVFs) after percutaneous vertebroplasty (PVP).... We retrospectively analyzed patients who underwent single-segment PVP for osteoporotic compression fractures in our hospital from January 2016 to January 2021 and divided the patients into 2 groups, A... A total of 570 patients were included in this study: 511 patients in group A and 59 patients in group B. There were no statistical differences in the general data such as age, gender, and fracture sit... The 3 evaluation methods reliably predict AVF after PVP, with the LAT method, PA and LAT method being more predictive than the PA method, but the LAT method is simpler, with bone cement being widely d...

Critical thinking among institutional academic advisors and sociodemographic, professional and academic variables: A multicenter correlation study.

In nursing education, essential skills include Critical Thinking (CT). There is scant evidence on how nurse educators could promote CT in students in a clinical context.... To analyse the level of CT and correlated variables in healthcare nurses overseeing the clinicals of nursing undergraduates.... The study population were all nurse educators for clinicals at hospitals with nursing undergraduates. To evaluate the CT skills of nurses the Nursing Critical Thinking in Clinical Practice Questionnai... The total number of participants was 639. The highest mean CT level was seen in clinical nurses involved in undergraduate nursing instruction and with experience of up to 10 years (mean CT score = 372... CT levels are high in teaching healthcare professionals in the clinical environment....

Curvilinear relationship between burnout and work engagement among staff in community services for the elderly: A correlation study.

To investigate whether there is a curvilinear relationship between burnout and work engagement among staff in Chinese community services for the elderly.... A stratified whole-group random sampling method was used to survey 244 staff members from eight communities in two cities. Data were collected using the Maslach Burnout Inventory scale (MBI) and the U... Two hundred forty-four staff members completed the survey. Burnout, depersonalization (DP), and personal accomplishment (PA) were found to be related to work engagement in a cubic function (... There was a cubic function relationship between burnout and work engagement, where "personal accomplishment" was related to work engagement in a U-shaped curve. Therefore, the government and related s...

Correlation study of malignant lymphoma and breast Cancer in different gender European populations: mendelian randomization analysis.

Previous research has already indicated an elevated risk of breast cancer (BC) among survivors of malignant lymphoma, but the underlying reasons remain unknown. Our objective is to elucidate the causa... The analysis results from the FinnGen consortium indicate that there is no causal relationship between HL and NHL with BC. HL (OR = 1.01, 95% CI = 0.98-1.04, p = 0.29), NHL (OR = 1.01, 95% CI = 0.96-1... The two-sample MR analysis indicates that there is no significant causal relationship between malignant lymphoma (HL and NHL) and BC. The association between malignant lymphoma and breast cancer requi...

Towards better indications for kidney biopsy in adult IgA vasculitis: a clinical-laboratory and pathology correlation study.

Indications for kidney biopsy in adult IgA vasculitis (IgAV) remain debated and there are very few studies on this subject. The aim of this study was to establish a correlation between renal histologi... A retrospective multicenter study was conducted using three databases from French hospitals, gathered between 1977 and 2020. The study included 294 adult patients with IgAV who had undergone kidney bi... The patients were primarily men (64%), with a mean age of 52 years. The main organs and tissues involved were: dermatological 100%, digestive 48% and rheumatological 61%. All had features of kidney in... Our study suggests that there is no strict baseline correlation between renal pathology and clinical-laboratory data. Given the current knowledge, it seems relevant to recommend a kidney biopsy in the...

Correlation study on serum miR-222-3p and glucose and lipid metabolism in patients with polycystic ovary syndrome.

microRNAs (miRNAs) play pivotal roles in polycystic ovary syndrome (PCOS), an endocrine and metabolic disorder that commonly occurs in women of childbearing age. This paper aimed to measure miR-222-3p... Totally 111 PCOS patients and 94 healthy people were recruited and assigned to the overweight (ow) group and non-overweight (non-ow) group, followed by determination of serum miR-222-3p expression. Th... miR-222-3p was highly-expressed in PCOS patients (p < 0.001), in especially PCOS ow patients. The area under the curve (AUC) of miR-222-3p diagnosing PCOS non-ow patients was 0.9474 and cut-off value ... High expression of miR-222-3p assisted PCOS diagnosis and predicted increased risks of diabetic and cardiovascular complications. miR-222-3p targeted PGC-1α and was negatively-correlated with PGC-1α....

Childhood adiposity and novel subtypes of adult-onset diabetes: a Mendelian randomisation and genome-wide genetic correlation study.

We investigated whether the impacts of childhood adiposity on adult-onset diabetes differ across proposed diabetes subtypes using a Mendelian randomisation (MR) design.... We performed MR analysis using data from European genome-wide association studies of childhood adiposity, latent autoimmune diabetes in adults (LADA, proxy for severe autoimmune diabetes), severe insu... Higher levels of childhood adiposity had positive genetically predicted effects on LADA (OR 1.62, 95% CI 1.05, 2.52), SIDD (OR 2.11, 95% CI 1.18, 3.80), SIRD (OR 2.76, 95% CI 1.60, 4.75) and MOD (OR 7... Childhood adiposity is a risk factor not only for adult-onset diabetes primarily characterised by obesity or insulin resistance, but also for subtypes primarily characterised by insulin deficiency or ...

The causal relationship between air pollution, obesity, and COVID-19 risk: a large-scale genetic correlation study.

Observational evidence reported that air pollution is a significant risk element for numerous health problems, such as obesity and coronavirus disease 2019 (COVID-19), but their causal relationship is... We obtained instrumental variables strongly correlated to air pollutants [PM2.5, nitrogen dioxide (NO... PM2.5 genetically correlated with 5 obesity-related traits, which obesity class 1 was most affected (beta = 0.38, 95% CI = 0.11 - 0.65,... Our study suggested that exposure to heavy air pollutants causally increased risks for obesity. Besides, obesity causally increased the risks for COVID-19 phenotypes. Attention needs to be paid to wei...