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Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Molécules d'interaction stromale
Molécules d'interaction stromale : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Biopsie
Immunohistochimie
Marqueurs tumoraux
Tumeurs
Imagerie par résonance magnétique
Interactions cellulaires
Biopsie
Analyse histologique
Symptômes
5
Croissance tumorale
Symptômes
Tumeurs
Environnement tumoral
Symptômes précoces
Symptômes tardifs
Traitement
Réversibilité des symptômes
Prévention
5
Prévention
Facteurs de risque
Mode de vie sain
Prévention des tumeurs
Dépistage
Détection précoce
Éducation sur le cancer
Sensibilisation
Vaccins
Prévention du cancer
Traitements
5
Thérapies ciblées
Immunothérapie
Efficacité des traitements
Tumeurs
Effets secondaires
Réactions immunitaires
Médecine personnalisée
Profil moléculaire
Thérapies combinées
Efficacité des traitements
Complications
5
Progression tumorale
Complications
Gestion des complications
Suivi médical
Prévisibilité
Interactions tumorales
Qualité de vie
Complications
Facteurs de risque
5
Facteurs de risque
Inflammation chronique
Alimentation
Antioxydants
Antécédents familiaux
Prédisposition génétique
Toxines
Exposition environnementale
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"@type": "Question",
"name": "Quels tests sont utilisés pour les molécules stromales ?",
"position": 2,
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"name": "Les marqueurs stromaux sont-ils spécifiques ?",
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"@type": "Question",
"name": "Les interactions stromales causent-elles des symptômes ?",
"position": 7,
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"@type": "Question",
"name": "Comment les symptômes varient-ils selon les tumeurs ?",
"position": 8,
"acceptedAnswer": {
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"text": "Les symptômes dépendent du type de tumeur et de l'environnement stromal spécifique."
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{
"@type": "Question",
"name": "Les symptômes sont-ils précoces ou tardifs ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent être précoces ou tardifs, selon la nature de l'interaction stromale."
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{
"@type": "Question",
"name": "Les symptômes sont-ils réversibles ?",
"position": 10,
"acceptedAnswer": {
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"text": "Certains symptômes peuvent s'améliorer avec un traitement ciblant les interactions stromales."
}
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{
"@type": "Question",
"name": "Peut-on prévenir les interactions stromales ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par la réduction des facteurs de risque liés aux tumeurs et à l'inflammation."
}
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{
"@type": "Question",
"name": "Quels modes de vie aident à prévenir les tumeurs ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, peut réduire les risques."
}
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"@type": "Question",
"name": "Les dépistages réguliers sont-ils utiles ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les dépistages peuvent aider à détecter les tumeurs précocement, limitant les interactions stromales."
}
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{
"@type": "Question",
"name": "L'éducation sur le cancer est-elle importante ?",
"position": 14,
"acceptedAnswer": {
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"text": "Oui, l'éducation aide à sensibiliser aux facteurs de risque et aux signes précoces de cancer."
}
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{
"@type": "Question",
"name": "Les vaccins peuvent-ils prévenir les tumeurs ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains vaccins, comme ceux contre le HPV, peuvent réduire le risque de cancers associés."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les molécules stromales ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées et des immunothérapies sont en développement pour cibler ces molécules."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité varie selon le type de tumeur et la nature des interactions stromales."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires des traitements ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent entraîner des effets secondaires, notamment des réactions immunitaires."
}
},
{
"@type": "Question",
"name": "Comment les traitements sont-ils personnalisés ?",
"position": 19,
"acceptedAnswer": {
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"text": "Les traitements sont adaptés en fonction du profil moléculaire de la tumeur et de l'environnement stromal."
}
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{
"@type": "Question",
"name": "Les traitements sont-ils combinés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des combinaisons de traitements sont souvent utilisées pour améliorer l'efficacité."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la progression tumorale, la résistance au traitement et la métastase."
}
},
{
"@type": "Question",
"name": "Les interactions stromales aggravent-elles les complications ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent favoriser la progression tumorale et compliquer le traitement."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion implique des traitements ciblés et un suivi régulier pour adapter les thérapies."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles prévisibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être anticipées en fonction du type de tumeur et des interactions."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent significativement impacter la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque des interactions stromales ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'inflammation chronique, le tabagisme et des prédispositions génétiques."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle les risques ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en antioxydants peut réduire les risques d'interactions stromales."
}
},
{
"@type": "Question",
"name": "Le stress est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut influencer l'inflammation et augmenter le risque de complications."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de cancer peuvent augmenter le risque d'interactions stromales."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines est-elle un risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des substances toxiques peut favoriser les interactions stromales et le cancer."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 02/04/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, London, ON, N6A 5C1, Canada. Electronic address: pstatho@uwo.ca.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN.
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Institute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Richard L. Roudebush Veterans' Administration Medical Center, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN.
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Richard L. Roudebush Veterans' Administration Medical Center, Indianapolis, IN.
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2M9, Canada. Electronic address: mikura@uhnresearch.ca.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A5C1, Canada.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Xiamen University, College of Chemistry and Chemical Engineering & Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), CHINA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Xiamen University, College of Chemistry and Chemical Engineering, Siming south road 422, 3012, Xiamen, CHINA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physics, Indiana University Indianapolis, Indianpolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physics and Astronomy, Purdue University, West Lafayette, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
1 publication dans cette catégorie
Affiliations :
Universiti Sains Malaysia, Advanced Medical and Dental Institute, Department of Biomedical Science, Pulau Pinang, Malaysia
Hadhramout University, Faculty of Medicine and Health Sciences, Department of Basic Medical Sciences, Hadhramout, Yemen
Publications dans "Molécules d'interaction stromale" :
1 publication dans cette catégorie
Affiliations :
Universiti Sains Malaysia, Advanced Medical and Dental Institute, Department of Biomedical Science, Pulau Pinang, Malaysia
Publications dans "Molécules d'interaction stromale" :
Acromegaly is a systemic disease caused by excessive inappropriate secretion of GH and IGF-I levels, resulting in many systemic complications, including cardiovascular, respiratory, metabolic diseases...
Colonoscopy is a useful as a cancer screening test. However, in countries with limited medical resources, there are restrictions on the widespread use of endoscopy. Non-invasive screening methods to d...
We used data from physical exams and blood analyses to determine the incidence of colorectal polyp. However, these features exhibit highly overlapping classes. The use of a kernel density estimator (K...
Along with an adequate polyp size threshold, the optimal machine learning (ML) models' performance provided 0.37 and 0.39 Matthews correlation coefficient (MCC) for the datasets of men and women, resp...
The ML model can be chosen according to the desired polyp size discrimination threshold, may suggest further colorectal screening, and possible adenoma size. The KDE feature transformation could serve...
Both the clinical manifestation and molecular characteristics of colorectal cancer (CRC) vary according to the anatomical site. We explored the risk factors for four groups of colorectal neoplasms (CR...
We extracted data from the database of Tianjin Colorectal Cancer Screening Program from 2010 to 2020. According to the CRN anatomical sites, patients were divided into four groups: the proximal colon ...
The numbers of patients with CRN in the proximal colon, distal colon, rectum, and multiple colorectal sites were 4023, 6920, 3657, and 7938, respectively. Male sex was associated with a higher risk fr...
We observed differences in advanced age, obesity, smoking, alcohol consumption, and family history of colorectal cancer at different anatomical sites of colorectal neoplasms. These factors vary by gen...
National consensus recommendations have recently been developed to standardize colorectal tumour localization and documentation during colonoscopy. In this qualitative semi-structured interview study,...
Phytochemicals have long been effective partners in the fight against several diseases, including cancer. Among these, flavonoids are valuable allies for both cancer prevention and therapy since they ...
Colonoscopy is the standard of care for diagnosis and evaluation of colorectal cancers before surgery. However, varied practices and heterogenous documentation affects communication between endoscopis...
This study aimed to develop recommendations for the use of standardized localization and reporting practices for colorectal lesions identified during lower GI endoscopy....
A systematic review of existing endoscopy guidelines and thorough narrative review of the overall endoscopy literature were performed to identify existing practices recommended globally....
An online Delphi process was used to establish consensus recommendations based on a literature review....
Colorectal surgeons and gastroenterologists from across Canada who had previously demonstrated leadership in endoscopy, managed large endoscopy programs, produced high-impact publications in the field...
The primary outcomes measured were colorectal lesion localization and documentation practice recommendations important to planning surgical or advanced endoscopic excisions....
A total of 129 of 197 statements achieved consensus after 3 rounds of voting by 23 experts from across Canada. There was more than 90% participation in each round. Recommendations varied according to ...
Because of a paucity of evidence, recommendations are based primarily on expert opinion. There may be bias, as all representatives were based in Canada....
Best practices to optimize endoscopic lesion localization and communication are not addressed in previous guidelines. This consensus involving national experts in colorectal surgery and gastroenterolo...
ANTECEDENTES:La colonoscopia es el estándar de atención para el diagnóstico y la evaluación de los cánceres colorrectales antes de la cirugía. Sin embargo, las prácticas variadas y la documentación he...
The Asia-Pacific Colorectal Screening (APCS) scoring system was developed to stratify the risk of colorectal advanced neoplasm (AN). We aimed to evaluate the performance of the APCS score combined wit...
A total of 2842 subjects who visited outpatient clinics or cancer screening centers were enrolled. Age, sex, smoking status, and family history were recorded and APCS scores were calculated in 2439 pa...
Based on the APCS score, 38.8% (946 of 2439) of the subjects were categorized as high risk, and they had a 1.8-fold increase in risk for AN (95% CI, 1.4-2.3) compared with low and moderate risk. The A...
The APCS score combined with a stool DNA test significantly improved the detection of colorectal ANs, while limiting colonoscopy resource utilization (Chictr.org.cn, ChiCTR-DDD-17011169)....
Screening recommendations for colorectal cancer (CRC) are mainly based on family history rather than lifestyle risk factors. We aimed to assess and compare risk factors for colorectal neoplasm (CRN) a...
This study was based on 89,535 first-recorded colonoscopies in Tianjin CRC screening program, 2012-2020. Of these, 45,380 individuals with complete family history and lifestyle factors were included f...
The overall detection rate of nonadvanced adenomas, advanced adenomas and CRC was 39.3%, 5.9% and 1.5%, respectively. The PAFs of current smoking, alcohol consumption, physical activity, higher BMI an...
Modifiable lifestyle factors, including smoking, alcohol consumption, physical activity and BMI, have a larger contribution to CRN than family history of CRC. Our findings will provide references for ...
Colonoscopy is the gold standard for diagnosing colorectal neoplasms. However, colonoscopy is often repeated preoperatively due to non-standard documentation and inconsistent practices by index endosc...
We performed a retrospective review of patients who underwent elective surgery for colorectal neoplasms at a single institution in Winnipeg between 2007-2020. We compared endoscopy report quality to t...
One hundred ninety-four patients were included (97 rural, 97 urban). The mean overall compliance with the recommendations for urban endoscopies was marginally better compared to rural endoscopies (50%...
Endoscopists frequently omit recommended practices for optimal colorectal lesion localization. Rural reports miss more recommended information compared to urban reports. Future research is needed to f...
A positive resection margin after colorectal endoscopic submucosal dissection (ESD) is associated with an increased risk of recurrence. We aimed to identify the clinical significance of positive resec...