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Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Molécules d'interaction stromale
Molécules d'interaction stromale : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Biopsie
Immunohistochimie
Marqueurs tumoraux
Tumeurs
Imagerie par résonance magnétique
Interactions cellulaires
Biopsie
Analyse histologique
Symptômes
5
Croissance tumorale
Symptômes
Tumeurs
Environnement tumoral
Symptômes précoces
Symptômes tardifs
Traitement
Réversibilité des symptômes
Prévention
5
Prévention
Facteurs de risque
Mode de vie sain
Prévention des tumeurs
Dépistage
Détection précoce
Éducation sur le cancer
Sensibilisation
Vaccins
Prévention du cancer
Traitements
5
Thérapies ciblées
Immunothérapie
Efficacité des traitements
Tumeurs
Effets secondaires
Réactions immunitaires
Médecine personnalisée
Profil moléculaire
Thérapies combinées
Efficacité des traitements
Complications
5
Progression tumorale
Complications
Gestion des complications
Suivi médical
Prévisibilité
Interactions tumorales
Qualité de vie
Complications
Facteurs de risque
5
Facteurs de risque
Inflammation chronique
Alimentation
Antioxydants
Antécédents familiaux
Prédisposition génétique
Toxines
Exposition environnementale
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour les molécules stromales ?",
"position": 2,
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"@type": "Question",
"name": "Les marqueurs stromaux sont-ils spécifiques ?",
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"@type": "Question",
"name": "Les interactions stromales causent-elles des symptômes ?",
"position": 7,
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"text": "Oui, elles peuvent influencer la croissance tumorale et provoquer des symptômes associés."
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"@type": "Question",
"name": "Comment les symptômes varient-ils selon les tumeurs ?",
"position": 8,
"acceptedAnswer": {
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"text": "Les symptômes dépendent du type de tumeur et de l'environnement stromal spécifique."
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{
"@type": "Question",
"name": "Les symptômes sont-ils précoces ou tardifs ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent être précoces ou tardifs, selon la nature de l'interaction stromale."
}
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{
"@type": "Question",
"name": "Les symptômes sont-ils réversibles ?",
"position": 10,
"acceptedAnswer": {
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"text": "Certains symptômes peuvent s'améliorer avec un traitement ciblant les interactions stromales."
}
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{
"@type": "Question",
"name": "Peut-on prévenir les interactions stromales ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par la réduction des facteurs de risque liés aux tumeurs et à l'inflammation."
}
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{
"@type": "Question",
"name": "Quels modes de vie aident à prévenir les tumeurs ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, peut réduire les risques."
}
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"@type": "Question",
"name": "Les dépistages réguliers sont-ils utiles ?",
"position": 13,
"acceptedAnswer": {
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"text": "Oui, les dépistages peuvent aider à détecter les tumeurs précocement, limitant les interactions stromales."
}
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{
"@type": "Question",
"name": "L'éducation sur le cancer est-elle importante ?",
"position": 14,
"acceptedAnswer": {
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"text": "Oui, l'éducation aide à sensibiliser aux facteurs de risque et aux signes précoces de cancer."
}
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"@type": "Question",
"name": "Les vaccins peuvent-ils prévenir les tumeurs ?",
"position": 15,
"acceptedAnswer": {
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"text": "Certains vaccins, comme ceux contre le HPV, peuvent réduire le risque de cancers associés."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les molécules stromales ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées et des immunothérapies sont en développement pour cibler ces molécules."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité varie selon le type de tumeur et la nature des interactions stromales."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires des traitements ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
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}
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{
"@type": "Question",
"name": "Comment les traitements sont-ils personnalisés ?",
"position": 19,
"acceptedAnswer": {
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"text": "Les traitements sont adaptés en fonction du profil moléculaire de la tumeur et de l'environnement stromal."
}
},
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"@type": "Question",
"name": "Les traitements sont-ils combinés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des combinaisons de traitements sont souvent utilisées pour améliorer l'efficacité."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la progression tumorale, la résistance au traitement et la métastase."
}
},
{
"@type": "Question",
"name": "Les interactions stromales aggravent-elles les complications ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent favoriser la progression tumorale et compliquer le traitement."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion implique des traitements ciblés et un suivi régulier pour adapter les thérapies."
}
},
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"@type": "Question",
"name": "Les complications sont-elles prévisibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être anticipées en fonction du type de tumeur et des interactions."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent significativement impacter la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque des interactions stromales ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'inflammation chronique, le tabagisme et des prédispositions génétiques."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle les risques ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en antioxydants peut réduire les risques d'interactions stromales."
}
},
{
"@type": "Question",
"name": "Le stress est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut influencer l'inflammation et augmenter le risque de complications."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de cancer peuvent augmenter le risque d'interactions stromales."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines est-elle un risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des substances toxiques peut favoriser les interactions stromales et le cancer."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 02/04/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, London, ON, N6A 5C1, Canada. Electronic address: pstatho@uwo.ca.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN.
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Institute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Richard L. Roudebush Veterans' Administration Medical Center, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
3 publications dans cette catégorie
Affiliations :
Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN.
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
Richard L. Roudebush Veterans' Administration Medical Center, Indianapolis, IN.
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2M9, Canada. Electronic address: mikura@uhnresearch.ca.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A5C1, Canada.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Xiamen University, College of Chemistry and Chemical Engineering & Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), CHINA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Xiamen University, College of Chemistry and Chemical Engineering, Siming south road 422, 3012, Xiamen, CHINA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physics, Indiana University Indianapolis, Indianpolis, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
2 publications dans cette catégorie
Affiliations :
Department of Physics and Astronomy, Purdue University, West Lafayette, Indiana, USA.
Publications dans "Molécules d'interaction stromale" :
1 publication dans cette catégorie
Affiliations :
Universiti Sains Malaysia, Advanced Medical and Dental Institute, Department of Biomedical Science, Pulau Pinang, Malaysia
Hadhramout University, Faculty of Medicine and Health Sciences, Department of Basic Medical Sciences, Hadhramout, Yemen
Publications dans "Molécules d'interaction stromale" :
1 publication dans cette catégorie
Affiliations :
Universiti Sains Malaysia, Advanced Medical and Dental Institute, Department of Biomedical Science, Pulau Pinang, Malaysia
Publications dans "Molécules d'interaction stromale" :
To investigate the determinants of hand strength in patients with hand osteoarthritis (OA)....
Pinch and cylinder grip strength were measured in 527 patients with hand OA diagnosed by their treating rheumatologist from the Hand OSTeoArthritis in Secondary care (HOSTAS) study. Radiographs of han...
Hand strength was negatively associated with female sex, age, and pain. Reduced hand strength was associated with reduced quality of life, although less after adjusting for pain. Radiographic features...
Subluxation of CMC1 is associated with reduced grip strength, whereas associations with other radiographic features seem to be confounded by age. In the relationship between age and hand strength, rad...
Hand grip strength (HGS) is a widely used functional test for the assessment of strength and functional status in patients with cancer, in particular with cancer cachexia. The aim was to prospectively...
In this prospective study, 333 patients with cancer (85% stage III/IV) and 65 healthy controls of similar age and sex were enrolled. None of the study participants had significant cardiovascular disea...
The mean age was 60 ± 14 years; 163 (51%) were female, and 148 (44%) had cachexia at baseline. Patients with cancer showed 18% lower HGS than healthy controls (31.2 ± 11.9 vs. 37.9 ± 11.6 kg, P < 0.00...
Reduced maximal HGS was associated with higher all-cause mortality, reduced overall functional status and decreased physical performance in patients with mostly advanced cancer. Similar results were f...
To explore the associations between hand grip strength (HGS) and ocular parameters and diseases....
Population-based cohort study....
Participants of the Ural Eye and Medical Study, including 5899 (80.5%) out of 7328 eligible individuals aged 40+ years, underwent systemic and ophthalmological examinations including dynamometric HGS ...
The study included 5381 (90.4%) individuals (age: 58.6±10.6 years; range: 40-94 years) with HGS measurements. Higher HGS (mean: 30.6±11.7 dekaNewton) correlated (multivariable analysis) with better vi...
In addition to parameters such as lower physical activity, higher depression score and worse general health status, a reduced HGS is associated with visual impairment, shorter axial length, lower intr...
Skeletal muscle index (SMI), the gold standard for sarcopenia, cannot measure muscle strength and requires specialized software and training. Hand-grip strength (HGS) measurement is cheap, requires mi...
Consecutive male DC patients (n=155) were enrolled. Baseline liver functions, etiologic work-up and anthropometric measurements were done. SMI was determined from computed tomography (CT) images at L3...
Mean HGS and SMI were 25.73 ± 5.94 kg and 47.72 ± 8.71 cm...
Prevalence of sarcopenia in Indian male patients with DC is 26.5%. HGS is an independent predictor of sarcopenia and can be used as a screening tool to stratify the need for confirmatory CT-based asse...
The aim of this study is to examine the age-related changes in the toe grip strength and its differences from hand grip strength and knee extension strength using cross-sectional data....
Of participants aged 65 years over who underwent health checkups for lifestyle-related diseases in 2018, 307 men and women met the criteria. Toe grip strength, hand grip strength, and knee extension s...
In men, there were interaction effects between the factors of age and muscle, but in women there were not. Toe grip strength was significantly lower in Group 70, 75, 80, and 85 in men, lower in Group ...
The decline in toe grip strength may occur earlier and in a different pattern from hand grip strength and knee extension strength in men....
Sarcopenia is mainly results from aging; however, it is more prevalent in chronic airway disease such as obstructive pulmonary disease (COPD). Hand grip strength (HGS) can be used as an indicator to e...
We conducted a cross-sectional study using data from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2014 to 2018. Subjects aged ≥40 years who underwent both spirometry and H...
Among 15,950 subjects, 2277 (14.3%) had AFL with mean FEV...
Lower HGS is significantly associated with moderate-to-very severe AFL in age-, sex-, and BMI-matched comparisons....
Grip strength is commonly used to assess hand function among older adults. While shown to be associated with disability, the degree to which grip strength specifically predicts hand limitations is unk...
The primary aim of this study was to evaluate grip strength as a predictor of hand limitations....
Using the 2011-14 National Health and Nutrition Examination Survey (NHANES), we classified older adults reporting one or more hand limitations versus those with no limitations. Odds ratios were used t...
We identified 2064 older adults (age ≥ 65), 31% of whom reported a hand-related limitation. Older adults with very low grip strength (weakest quartile) were more likely to report at least one limitati...
While self-reported hand limitations were associated with lower grip strength; overall, it is a relatively poor predictor of hand impairments among older adults....
Better assessments are needed to adequately evaluate upper extremity impairments to help older adults maintain functional independence....
Prevention of musculoskeletal occupational hazards is an important topic in extractive industries. This study quantifies the impact of three styles of industrial metacarpal gloves on dexterity, grippi...
Hand grip strength (HGS) is a widely used indicator of overall muscle strength and general health. We computed a polygenic risk score (PRS) for HGS and examined whether it predicted muscle strength, f...
Genomewide association study summary statistics for HGS from the Pan-UK Biobank was used. PRS were calculated in the Finnish Twin Study on Aging ( N = 429 women, 63-76 yr). Strength tests included HGS...
The measured HGS increased linearly over increasing PRS ( β = 4.8, SE = 0.93, P < 0.001). PRS HGS independently accounted for 6.1% of the variation in the measured HGS ( β = 14.2, SE = 3.1, P < 0.001)...
Older women with genetic risk for low muscle strength were significantly weaker than those with genetic susceptibility for high muscle strength. PRS HGS was also systematically associated with overall...
Modulating force between the thumb and another digit, or isometric pinch individuation, is critical for daily tasks and can be impaired due to central or peripheral nervous system injury. Because surg...