Titre : Déméthylation

Déméthylation : Questions médicales fréquentes

Termes MeSH sélectionnés :

Text Messaging
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"https://questionsmedicales.fr/mesh/D000073398?mesh_terms=Text+Messaging&page=5#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une déméthylation anormale ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques et des analyses de l'ADN peuvent révéler des modifications de méthylation." } }, { "@type": "Question", "name": "Quels marqueurs sont utilisés pour la déméthylation ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les marqueurs épigénétiques comme 5-méthylcytosine sont souvent analysés." } }, { "@type": "Question", "name": "Quels tests sanguins peuvent indiquer une déméthylation ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de métabolites et d'ADN circulant peuvent fournir des indices." } }, { "@type": "Question", "name": "La biopsie est-elle nécessaire pour diagnostiquer la déméthylation ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Une biopsie peut être nécessaire pour des analyses plus précises des tissus." } }, { "@type": "Question", "name": "Quels symptômes peuvent alerter sur une déméthylation ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes variés comme des troubles neurologiques ou des cancers peuvent survenir." } }, { "@type": "Question", "name": "Quels symptômes sont associés à la déméthylation ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes peuvent inclure des troubles cognitifs, des anomalies de croissance et des cancers." } }, { "@type": "Question", "name": "La déméthylation peut-elle causer des maladies ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle est liée à des maladies comme le cancer et des troubles génétiques." } }, { "@type": "Question", "name": "Y a-t-il des signes cliniques de déméthylation ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Des signes cliniques peuvent inclure des changements de comportement et des anomalies physiques." } }, { "@type": "Question", "name": "Les symptômes varient-ils selon l'âge ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes peuvent se manifester différemment selon l'âge et le développement." } }, { "@type": "Question", "name": "La déméthylation affecte-t-elle le système immunitaire ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Elle peut altérer la réponse immunitaire, augmentant le risque d'infections." } }, { "@type": "Question", "name": "Comment prévenir la déméthylation ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir la déméthylation." } }, { "@type": "Question", "name": "Les suppléments peuvent-ils aider ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Des suppléments comme l'acide folique peuvent soutenir la méthylation." } }, { "@type": "Question", "name": "Le stress influence-t-il la déméthylation ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut affecter les mécanismes de méthylation." } }, { "@type": "Question", "name": "L'exercice physique a-t-il un impact ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "L'exercice régulier peut améliorer la santé épigénétique et la méthylation." } }, { "@type": "Question", "name": "Les toxines environnementales jouent-elles un rôle ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à certaines toxines peut perturber les mécanismes de méthylation." } }, { "@type": "Question", "name": "Quels traitements existent pour la déméthylation ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des thérapies géniques et des médicaments ciblés." } }, { "@type": "Question", "name": "La nutrition peut-elle influencer la déméthylation ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains nutriments comme l'acide folique peuvent moduler la méthylation." } }, { "@type": "Question", "name": "Les thérapies épigénétiques sont-elles efficaces ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Elles montrent un potentiel prometteur dans le traitement de certains cancers." } }, { "@type": "Question", "name": "Peut-on prévenir la déméthylation par des médicaments ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Des inhibiteurs spécifiques peuvent être utilisés pour prévenir la déméthylation." } }, { "@type": "Question", "name": "Les traitements sont-ils personnalisés ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les traitements peuvent être adaptés en fonction du profil génétique du patient." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent des cancers, des troubles neurologiques et des maladies auto-immunes." } }, { "@type": "Question", "name": "La déméthylation est-elle réversible ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Certaines modifications peuvent être réversibles, mais pas toutes." } }, { "@type": "Question", "name": "Quels risques sont associés à la déméthylation ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les risques incluent des maladies chroniques et des troubles de développement." } }, { "@type": "Question", "name": "La déméthylation peut-elle affecter la fertilité ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut influencer la fertilité en altérant la fonction reproductive." } }, { "@type": "Question", "name": "Y a-t-il des effets à long terme ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Des effets à long terme peuvent inclure des prédispositions à diverses maladies." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque de déméthylation ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'alimentation, le stress, et l'exposition à des toxines." } }, { "@type": "Question", "name": "L'hérédité joue-t-elle un rôle ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs génétiques peuvent influencer la déméthylation." } }, { "@type": "Question", "name": "Les maladies chroniques augmentent-elles le risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Certaines maladies chroniques peuvent augmenter le risque de déméthylation." } }, { "@type": "Question", "name": "Le mode de vie influence-t-il la déméthylation ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie malsain peut favoriser la déméthylation." } }, { "@type": "Question", "name": "Les infections peuvent-elles affecter la déméthylation ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections peuvent perturber les mécanismes de méthylation." } } ] } ] }

Sources (3405 au total)

Analyzing text message linguistic features: Do people with depression communicate differently with their close and non-close contacts?

Relatively little is known about how communication changes as a function of depression severity and interpersonal closeness. We examined the linguistic features of outgoing text messages among individ... 419 participants were included in this 16-week-long observational study. Participants regularly completed the PHQ-8 and rated subjective closeness to their contacts. Text messages were processed to co... Regardless of closeness, people with higher PHQ-8 scores tended to use more differentiation words. When texting with close contacts, individuals with higher PHQ-8 scores used more first-person singula... Word classes used in text messages, when combined with symptom severity and subjective social closeness data, may be indicative of underlying interpersonal processes. These data may hold promise as po...

Effectiveness of a Text Message Intervention Promoting Seat Belt Use Among Young Adults: A Randomized Clinical Trial.

Approximately 1 in 10 adults do not always wear a seat belt, with the lowest use rates reported among young adults.... To determine the efficacy of a 6-week automated behavioral text message program promoting seat belt use compared with an attention control.... This parallel, 2-group, single-blind, individually randomized clinical trial included a convenience sample of patients recruited from 4 emergency departments in 2 cities in Pennsylvania from December ... The intervention group received Safe Vehicle Engagement (SAVE), a 6-week automated interactive text message program, including weekly seat belt use queries with feedback and goal support to promote co... The primary outcome was the proportion of young adults reporting always wearing a seat belt over the past 2 weeks, collected at 6 weeks (after a 2-week run-in) via web-based self-assessments and analy... A total of 218 participants (mean [SD] age, 21.5 [2.1] years; 139 [63.8%] women) were randomized, with 110 randomized to SAVE and 108 randomized to the control group. A total of 158 individuals (72.4%... In this randomized clinical trial, an interactive text message intervention was more effective at promoting seat belt use among targeted young adults than an attention control at 6 weeks. There was no... ClinicalTrials.gov Identifier: NCT03833713....

Randomized comparison of the effects of tailored text messaging versus pillbox organizers on medication adherence of heart failure patients.

Heart failure (HF) is a major public health issue worldwide, affecting approximately 64.3 million people in 2017. Non-adherence to medication is a common and serious issue in the management of HF. How... A randomized controlled trial was conducted, involving 189 eligible patients with HF who were randomly assigned to either the TTM, pillbox organizer, or control group. Medication adherence was evaluat... The results indicate that both the TTM and pillbox organizers groups had significantly higher medication adherence compared to the control group, as measured by pill counting (MD = 0.05, 95%CI = 0.03-... Both the TTM and pillbox organizers were shown to be effective in enhancing medication adherence among patients with HF. Therefore, healthcare providers should take into account the patient's conditio...

Desire to get drunk partially mediates effects of a combined text message-based alcohol intervention for young adults.

This study aimed to test the causal effect of different text message interventions on reducing alcohol consumption indirectly by altering desire to get drunk.... Participants were young adults randomized to interventions with different behavior change techniques: self-monitoring alone (TRACK); pre-drinking plan feedback (PLAN); post-drinking alcohol consumptio... At the between-person level, controlling for race and baseline AUDIT-C and within-person associations, 35.9 % of the effects of USE and 34.4 % of the effects of COMBO on reducing binge drinking were m... Findings support the hypothesized mediation model where desire to get drunk partially mediates the effects of a text message intervention using a combination of behavior change techniques on reducing ...

Systematic Literature Review of Text Messaging Interventions to Promote Medication Adherence Among People With Serious Mental Illness.

Mobile health tools are feasible options to encourage behavior change among patients with serious mental illness. Mobile health tools vary widely, both in platforms used and content delivered. This li... A systematic literature review using PRISMA guidelines examined short message service (SMS) text messaging interventions promoting medication adherence to people with a serious mental illness diagnosi... Of 114 full-text articles screened, 10 articles were selected from nine unique interventions (N=937 people with serious mental illness). Study durations ranged from 30 days to 18 months, with frequenc... Evidence to date indicates that text messaging interventions are feasible and appear to improve medication adherence and clinical outcomes among patients with serious mental illness. Future research s...

Opioid Consumption After Urogynecologic Surgery: A Prospective Multicenter Observational Study Using a Text-Messaging Survey Tool.

Understanding postoperative opioid consumption is key to reducing opioid misuse.... The aim of the study was to quantify the amount of outpatient opioids consumed after urogynecologic surgery.... This is a prospective multicenter cohort study sponsored by the American Urogynecologic Society Fellow's Pelvic Research Network. Women undergoing pelvic organ prolapse or urinary incontinence surgery... Two hundred sixty-one patients were included from 9 academic centers. The median (interquartile range) morphine milligram equivalents (MME) consumed were 28 (0-65) and prescribed were 75 (50-113). The... Urogynecology patients consume a median of 28 MME (3-4 oxycodone 5-mg tablets) after surgery, and surgeons prescribe 3 times this amount (75 MME, 10 oxycodone tablets). In addition, there are several ...

Evaluation of an Automated Text Message-Based Program to Reduce Use of Acute Health Care Resources After Hospital Discharge.

Posthospital contact with a primary care team is an established pillar of safe transitions. The prevailing model of telephone outreach is usually limited in scope and operationally burdensome.... To determine whether a 30-day automated texting program to support primary care patients after hospital discharge is associated with reductions in the use of acute care resources.... This cohort study used a difference-in-differences approach at 2 academic primary care practices in Philadelphia from January 27 through August 27, 2021. Established patients of the study practices wh... Patients received automated check-in text messages from their primary care practice on a tapering schedule during the 30 days after discharge. Any needs identified by the automated messaging platform ... The primary study outcome was any emergency department (ED) visit or readmission within 30 days of discharge. Secondary outcomes included any ED visit or any readmission within 30 days, analyzed separ... A total of 1885 patients (mean [SD] age, 63.2 [17.3] years; 1101 women [58.4%]) representing 2617 discharges (447 before and 604 after the intervention at the intervention practice; 613 before and 953... The findings of this cohort study suggest that an automated texting program to support primary care patients after hospital discharge was associated with significant reductions in use of acute care re...

Testing Mechanisms of Change for Text Message-Delivered Cognitive Behavioral Therapy: Randomized Clinical Trial for Young Adult Depression.

Current psychiatric epidemiological evidence estimates that 17% of young adults (aged 18-25 years) experienced a major depressive episode in 2020, relative to 8.4% of all adults aged ≥26 years. Young ... We conducted a randomized clinical trial following our initial 4-week SMS text message-delivered cognitive behavioral therapy (CBT-txt) for depression in young adults. We sought to test mechanisms of ... Based on participant feedback, outcome data, and the empirical literature, we increased the treatment dosage from 4-8 weeks and tested 3 mechanisms of change with 103 young adults in the United States... Across all 3 months of the study, participants in the CBT-txt group showed significantly larger decreases in depressive symptoms than those in the control group (P<.001 at each follow-up), producing a... Results provide evidence for the efficacy of CBT-txt to reduce young adult depressive symptoms through hypothesized mechanisms. To the best of our knowledge, CBT-txt is unique in its SMS text message-... ClinicalTrials.gov NCT05551702; https://clinicaltrials.gov/study/NCT05551702....

Randomized pilot trial of praise text messages to improve medication adherence among adolescents and young adults with liver transplants.

AYA who have undergone liver transplantations often struggle to adhere to their post-transplant immunosuppressant medications, which can lead to serious health complications. The objective of this pil... Thirty-five AYAs (13-21 years old) were randomized to either (1) receive praise text messages whenever laboratory results indicated immunosuppressant medications within the expected range or (2) usual... Multilevel, multivariate models showed significant associations between group assignment and some self-reported motivation and adherence outcomes but not MLVI. Specifically, AYA receiving the praise t... The results suggest texting patients about positive health indicators was acceptable and, with refinement, might promote AYA illness self-management....

Effectiveness and Acceptability of Targeted Text Message Reminders in Colorectal Cancer Screening: Randomized Controlled Trial (M-TICS Study).

Mobile phone-based SMS text message reminders have the potential to improve colorectal cancer screening participation rates.... This study assessed the effectiveness and acceptability of adding targeted SMS text message reminders to the standard procedure for those who picked up but did not return their screening kit at the ph... We performed a randomized control trial among individuals who picked up a fecal immunochemical test (FIT) kit for colorectal cancer screening at the pharmacy but did not return it within 14 days. The ... The intervention group had higher FIT completion rates than the control group at 30 (64.2% vs 53.7%; P<.001), 60 (78.6% vs 72.0%; P<.001), and 126 (82.6% vs 77.7%; P<.001) days. Participation rates we... Adding an SMS text message reminder to the standard procedure significantly increased FIT kit return rates and was a cost-effective strategy. SMS text messages also proved to be an acceptable and appr... ClinicalTrials.gov NCT04343950; https://www.clinicaltrials.gov/study/NCT04343950.... RR2-10.1371/journal.pone.0245806....