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"name": "Diagnostic",
"headline": "Diagnostic sur Membrane basilaire",
"description": "Comment évaluer la fonction de la membrane basilaire ?\nQuels examens sont utilisés pour diagnostiquer des troubles auditifs ?\nQuels signes indiquent un dysfonctionnement de la membrane basilaire ?\nComment les tests de réflexe acoustique aident-ils au diagnostic ?\nQuel rôle joue l'oto-rhino-laryngologiste dans le diagnostic ?",
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"headline": "Symptômes sur Membrane basilaire",
"description": "Quels symptômes sont associés à des problèmes de membrane basilaire ?\nComment les acouphènes se manifestent-ils ?\nLes vertiges sont-ils un signe de dysfonction de la membrane basilaire ?\nPeut-on ressentir une pression dans l'oreille ?\nLes changements de l'audition sont-ils fréquents ?",
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"headline": "Prévention sur Membrane basilaire",
"description": "Comment prévenir les troubles de la membrane basilaire ?\nLes examens auditifs réguliers sont-ils importants ?\nL'hygiène auditive joue-t-elle un rôle ?\nLes vaccinations peuvent-elles aider à prévenir des infections ?\nFaut-il éviter certains médicaments ?",
"url": "https://questionsmedicales.fr/mesh/D001489?mesh_terms=REM+Sleep+Behavior+Disorder&page=2#section-prévention"
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"headline": "Traitements sur Membrane basilaire",
"description": "Quels traitements existent pour les troubles de la membrane basilaire ?\nLes corticostéroïdes sont-ils efficaces pour traiter ces troubles ?\nQuand la chirurgie est-elle envisagée ?\nLes thérapies sonores peuvent-elles aider ?\nComment les appareils auditifs améliorent-ils l'audition ?",
"url": "https://questionsmedicales.fr/mesh/D001489?mesh_terms=REM+Sleep+Behavior+Disorder&page=2#section-traitements"
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"name": "Complications",
"headline": "Complications sur Membrane basilaire",
"description": "Quelles complications peuvent survenir avec des troubles de la membrane basilaire ?\nLes infections de l'oreille peuvent-elles causer des complications ?\nComment les troubles de l'équilibre sont-ils liés à la membrane basilaire ?\nLes acouphènes peuvent-ils devenir chroniques ?\nLes troubles auditifs peuvent-ils affecter la santé mentale ?",
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"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Membrane basilaire",
"description": "Quels sont les facteurs de risque pour les troubles de la membrane basilaire ?\nL'âge est-il un facteur de risque ?\nLes antécédents médicaux influencent-ils le risque ?\nLe mode de vie peut-il affecter la santé auditive ?\nLes maladies systémiques sont-elles un facteur de risque ?",
"url": "https://questionsmedicales.fr/mesh/D001489?mesh_terms=REM+Sleep+Behavior+Disorder&page=2#section-facteurs de risque"
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"@type": "Question",
"name": "Comment évaluer la fonction de la membrane basilaire ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests auditifs comme l'audiométrie peuvent évaluer la fonction de la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Quels examens sont utilisés pour diagnostiquer des troubles auditifs ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IRM et la tomodensitométrie peuvent aider à diagnostiquer des anomalies de la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent un dysfonctionnement de la membrane basilaire ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes incluent des pertes auditives, des acouphènes ou des vertiges."
}
},
{
"@type": "Question",
"name": "Comment les tests de réflexe acoustique aident-ils au diagnostic ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils mesurent la réponse de la membrane basilaire aux sons, indiquant des dysfonctionnements."
}
},
{
"@type": "Question",
"name": "Quel rôle joue l'oto-rhino-laryngologiste dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'oto-rhino-laryngologiste évalue les troubles auditifs et examine la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés à des problèmes de membrane basilaire ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des pertes auditives, des vertiges et des acouphènes."
}
},
{
"@type": "Question",
"name": "Comment les acouphènes se manifestent-ils ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les acouphènes se manifestent par des bruits perçus sans source externe, souvent liés à des troubles de la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Les vertiges sont-ils un signe de dysfonction de la membrane basilaire ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les vertiges peuvent indiquer une dysfonction de la membrane basilaire ou des structures associées."
}
},
{
"@type": "Question",
"name": "Peut-on ressentir une pression dans l'oreille ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une pression dans l'oreille peut être liée à des problèmes de membrane basilaire."
}
},
{
"@type": "Question",
"name": "Les changements de l'audition sont-ils fréquents ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des changements d'audition peuvent survenir avec des troubles de la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Comment prévenir les troubles de la membrane basilaire ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter l'exposition à des bruits forts et protéger les oreilles peut aider à prévenir ces troubles."
}
},
{
"@type": "Question",
"name": "Les examens auditifs réguliers sont-ils importants ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des examens réguliers peuvent détecter précocement des problèmes liés à la membrane basilaire."
}
},
{
"@type": "Question",
"name": "L'hygiène auditive joue-t-elle un rôle ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, maintenir une bonne hygiène auditive peut prévenir les infections et les troubles associés."
}
},
{
"@type": "Question",
"name": "Les vaccinations peuvent-elles aider à prévenir des infections ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines vaccinations peuvent prévenir des infections qui affectent l'oreille interne."
}
},
{
"@type": "Question",
"name": "Faut-il éviter certains médicaments ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments ototoxiques doivent être évités pour protéger la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour les troubles de la membrane basilaire ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des appareils auditifs, des médicaments et parfois la chirurgie."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces pour traiter ces troubles ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les corticostéroïdes peuvent réduire l'inflammation et améliorer l'audition dans certains cas."
}
},
{
"@type": "Question",
"name": "Quand la chirurgie est-elle envisagée ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chirurgie est envisagée en cas de malformations ou de lésions graves de la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Les thérapies sonores peuvent-elles aider ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les thérapies sonores peuvent aider à gérer les symptômes d'acouphènes liés à la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Comment les appareils auditifs améliorent-ils l'audition ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les appareils auditifs amplifient les sons, aidant à compenser la perte auditive due à des problèmes de membrane basilaire."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des troubles de la membrane basilaire ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des pertes auditives permanentes et des troubles d'équilibre."
}
},
{
"@type": "Question",
"name": "Les infections de l'oreille peuvent-elles causer des complications ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections non traitées peuvent entraîner des complications graves affectant la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Comment les troubles de l'équilibre sont-ils liés à la membrane basilaire ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les troubles de l'équilibre peuvent résulter de dysfonctionnements dans la membrane basilaire et les structures associées."
}
},
{
"@type": "Question",
"name": "Les acouphènes peuvent-ils devenir chroniques ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les acouphènes peuvent devenir chroniques et affecter la qualité de vie si non traités."
}
},
{
"@type": "Question",
"name": "Les troubles auditifs peuvent-ils affecter la santé mentale ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les troubles auditifs peuvent entraîner de l'anxiété et de la dépression chez certains patients."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les troubles de la membrane basilaire ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'exposition au bruit, l'âge avancé et des antécédents familiaux."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement est un facteur de risque majeur pour les troubles auditifs liés à la membrane basilaire."
}
},
{
"@type": "Question",
"name": "Les antécédents médicaux influencent-ils le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents de maladies de l'oreille ou d'infections augmentent le risque de troubles."
}
},
{
"@type": "Question",
"name": "Le mode de vie peut-il affecter la santé auditive ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie avec exposition fréquente à des bruits forts augmente le risque de troubles auditifs."
}
},
{
"@type": "Question",
"name": "Les maladies systémiques sont-elles un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies comme le diabète peuvent augmenter le risque de troubles auditifs."
}
}
]
}
]
}
Isolated REM sleep behavior disorder (iRBD) is strongly associated with synucleinopathies. Previous iRBD cohort studies have primarily focused on older (>50 years), male-predominant cohorts. Risk of p...
One hundred eighty-six women and 186 men with iRBD were matched by polysomnography month. Baseline clinical variables and subsequent neurodegenerative outcomes were abstracted by chart review. Kaplan-...
Age at iRBD diagnosis was younger in women compared with men (54.9 vs 62.5 years,...
Age at diagnosis was independently associated with phenoconversion risk in women and men with iRBD....
Degeneration of the nucleus basalis of Meynert (NBM) has been implicated in cognitive impairments in Parkinson's disease. The role of the NBM volumes in the cognitive function in isolated rapid eye mo...
We investigated changes in NBM volumes and their associations with cognitive deficits in iRBD. Baseline NBM volumes were compared between 29 iRBD patients and 29 healthy controls by using structural M...
Compared with controls, NBM volumes were significantly reduced in iRBD patients. In patients with iRBD, higher NBM volumes were significantly associated with greater performance in global cognition fu...
This study provides important in vivo evidence for an association between the NBM degeneration and cognitive impairments in iRBD....
It is reported that a diet that lowers oxidative stress reduces the prodromal Parkinson's disease (pPD) probability as well as the risk of Parkinson's disease (PD). In this study, we evaluated whether...
Polysomnography (PSG)-confirmed iRBD patients from the Neurology Department at Seoul National University Hospital were enrolled. We calculated the pPD probability using the "Web-based Medical Calculat...
We enrolled 101 patients with iRBD. The mean RFS score of patients with iRBD was 28.23 ± 9.29, which did not differ from the general population. Among patients with iRBD, the probability of pPD did no...
Diet quality assessed by RFS did not differ between the general population and patients with iRBD in Korea. Further studies are needed to confirm these protective effects of legume consumption on iRBD...
Mild cognitive impairment (MCI) is frequently diagnosed in patients with isolated rapid eye movement (REM) sleep behavior disorder (iRBD), although the extent of MCI-associated neuropathology has not ...
Sixty-one patients with iRBD were included in the study: 30 patients were included in the MCI subgroup (RBD-MCI) and 31 in the normal cognition subgroup (RBD-NC). Both groups underwent neuropsychiatri...
Neuropsychological measures generally confirmed overall cognitive decline in patients with iRBD-MCI. Immediate long-term verbal memory and visuospatial functions, as well as attentional-executive impa...
This study confirmed that iRBD patients with MCI had a more impaired cognitive status that those with NC. Moreover, the MCI subgroup presented reduced cerebral glucose consumption in brain areas criti...
Severe obstructive sleep apnea (OSA) in patients with rapid eye movement (REM) sleep behavior disorder (RBD) may result in frequent fragmentation of REM sleep and consequently lead to a false negative...
Patients with clinically diagnosed idiopathic RBD were included. RBD was confirmed if a video-PSG demonstrated complex motor behavior during REM sleep or REM sleep without atonia (RWA). Motor behavior...
Of a total 254 patients included, a diagnosis of RBD was confirmed by a video-PSG in 221 patients (87.0%). RWA, vocalization, and axial or proximal muscle movements in REM sleep were noted in 86.6%, 5...
OSA that requires CPAP may reduce a diagnostic accuracy for RBD by a video-PSG. False negative results were probably due to frequent electromyographic artifacts and/or severe sleep disruption from apn...
Previous studies revealed that sleep disorders are potential risk factors for cardiovascular diseases, such as obstructive sleep apnea and rapid eye movement (REM) sleep behavior disorder (RBD). Howev...
We used the latest and largest summary-level genome-wide association studies of RBD, stroke and its subtypes, coronary artery disease (CAD), myocardial infarction (MI), and heart failure (HF) to selec...
After multiple comparisons, genetically predicted RBD was significantly associated with the risk of HF [odds ratio (OR) = 1.033, 95% CI 1.013-1.052, p = 0.001]. Leave-one-out analysis further supporte...
Our study highlighted the potential associations between RBD and cardiovascular diseases at genetic level, including HF and MI. More studies were required to clarify the biological mechanisms involved...
Constipation, rapid eye movement sleep behavior disorder (RBD) and hyposmia are common prodromal symptoms of Parkinson's disease (PD), and they may represent two distinct types of disease origin, from...
A total of 111 de novo, drug-naïve Chinese PD patients were consecutively enrolled from Jan 2017 to Sept 2021. Patients were classified into PD with and without constipation based on item 5 of the Sca...
In total, 44.1% (n = 49) of de novo PD patients had constipation. PD patients with constipation were older (p = 0.028), had higher proportions of Hoehn and Yahr (H-Y) stage [Formula: see text] 2 (p = ...
RBD is closely associated with constipation in de novo Chinese PD patients. Our results support the theory that prodromal symptoms that represent the same pathological origin are closely related to ea...
Rapid eye movement (REM) sleep behavior disorder (RBD) could develop preceding or come after motor symptoms during Parkinson's disease (PD). It remains unknown that whether PD with different timing of...
We recruited 157 PD, 16 isolated RBD (iRBD), and 78 healthy controls. PD patients were identified as (1) PD with RBD preceding motor symptoms (PD-preRBD, n = 50), (2) PD with RBD posterior to motor sy...
The model predicted that SN occupied the highest likelihood in the maximum likelihood sequence of disease progression in the all PD subgroups, while LC was specifically positioned earlier to SN in iRB...
The spatiotemporal sequence of neurodegeneration between PD-pre and PD-post were similar but distinct from PD-nonRBD. The presence of RBD may be the essential factor for differentiating the degenerati...
Most patients with idiopathic REM sleep behavior disorder (iRBD) will develop an overt α-synucleinopathy over time, with a rate of phenoconversion of 73.5% after 12 years from diagnosis. Several marke...
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration. BDNF enhances the survival of dopaminergic neurons and improves dopaminergic neurotransmission and motor perfor...
We employed the Rapid Eye Movement Sleep Behavior Disorder Questionnaire-Hong Kong version (RBDQ-HK) and the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ) for RBD diagnosi...
Our findings indicate that serum BDNF levels were significantly lower in PD patients compared to healthy controls (p < 0.001). PD-RBD patients exhibited higher motor symptom scores (UPDRS III) than PD...
This study illustrates that decreased serum BDNF levels may be linked to the development of RBD in PD patients, highlighting the potential utility of BDNF as a biomarker in clinical practice....
