Titre : Benzodiazépines

Benzodiazépines : Questions médicales fréquentes

Nom anglais: Benzodiazepines

Descriptor UI: D001569

Tree Number: D03.633.100.079.080

Termes MeSH sélectionnés :

Analgesics, Opioid

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Comment diagnostiquer une dépendance aux benzodiazépines ?

Le diagnostic repose sur l'évaluation des symptômes et l'historique d'utilisation des médicaments.
Dépendance aux médicaments Benzodiazépines
#2

Quels tests sont utilisés pour évaluer l'usage des benzodiazépines ?

Des tests de dépistage de drogues et des évaluations psychologiques peuvent être utilisés.
Tests de dépistage Benzodiazépines
#3

Quels critères DSM sont utilisés pour le diagnostic ?

Les critères DSM-5 incluent l'usage excessif et les symptômes de sevrage.
Troubles liés à l'usage de substances Benzodiazépines
#4

Comment évaluer l'efficacité d'un traitement par benzodiazépines ?

L'efficacité est évaluée par la réduction des symptômes d'anxiété ou d'insomnie.
Évaluation clinique Benzodiazépines
#5

Quels signes indiquent une surdose de benzodiazépines ?

Les signes incluent confusion, somnolence excessive et difficultés respiratoires.
Syndrome de sevrage Benzodiazépines

Symptômes 5

#1

Quels sont les effets secondaires courants des benzodiazépines ?

Les effets secondaires incluent somnolence, vertiges et troubles de la mémoire.
Effets indésirables Benzodiazépines
#2

Comment reconnaître une réaction allergique aux benzodiazépines ?

Les réactions allergiques peuvent se manifester par éruptions cutanées et démangeaisons.
Réactions allergiques Benzodiazépines
#3

Quels symptômes indiquent un sevrage des benzodiazépines ?

Les symptômes de sevrage incluent anxiété, insomnie et tremblements.
Syndrome de sevrage Benzodiazépines
#4

Les benzodiazépines provoquent-elles des troubles cognitifs ?

Oui, elles peuvent entraîner des troubles de la mémoire et de la concentration.
Troubles cognitifs Benzodiazépines
#5

Quels symptômes peuvent nécessiter une consultation médicale urgente ?

Des symptômes comme confusion sévère ou difficultés respiratoires nécessitent une urgence.
Urgences médicales Benzodiazépines

Prévention 5

#1

Comment prévenir la dépendance aux benzodiazépines ?

La prévention inclut une prescription prudente et une éducation sur les risques.
Prévention de la dépendance Benzodiazépines
#2

Quels conseils donner aux patients sur l'utilisation des benzodiazépines ?

Les patients doivent être informés des risques et de l'importance de suivre les prescriptions.
Éducation des patients Benzodiazépines
#3

Comment surveiller l'utilisation des benzodiazépines ?

Les médecins doivent effectuer des suivis réguliers pour évaluer l'usage et les effets.
Suivi médical Benzodiazépines
#4

Quelles stratégies non médicamenteuses peuvent aider ?

Des techniques comme la méditation et l'exercice physique peuvent réduire l'anxiété.
Thérapies alternatives Benzodiazépines
#5

Comment sensibiliser sur les risques des benzodiazépines ?

Des campagnes d'information et des ateliers peuvent sensibiliser le public aux risques.
Sensibilisation Benzodiazépines

Traitements 5

#1

Comment traiter une dépendance aux benzodiazépines ?

Le traitement inclut une désintoxication supervisée et une thérapie comportementale.
Dépendance aux médicaments Benzodiazépines
#2

Quelles alternatives existent aux benzodiazépines pour l'anxiété ?

Les alternatives incluent les antidépresseurs et les thérapies cognitivo-comportementales.
Antidépresseurs Benzodiazépines
#3

Comment réduire progressivement l'utilisation des benzodiazépines ?

La réduction doit être progressive, sous supervision médicale pour éviter le sevrage.
Sevrage Benzodiazépines
#4

Quels médicaments peuvent aider à gérer le sevrage ?

Des médicaments comme le diazépam peuvent être utilisés pour atténuer les symptômes de sevrage.
Sevrage Benzodiazépines
#5

Quelle est la durée recommandée pour l'utilisation des benzodiazépines ?

L'utilisation est généralement recommandée pour une courte durée, souvent moins de 4 semaines.
Durée du traitement Benzodiazépines

Complications 5

#1

Quelles complications peuvent survenir avec l'usage prolongé ?

L'usage prolongé peut entraîner des troubles cognitifs et une dépendance sévère.
Complications Benzodiazépines
#2

Comment les benzodiazépines affectent-elles la santé mentale ?

Elles peuvent aggraver des troubles mentaux comme la dépression et l'anxiété.
Santé mentale Benzodiazépines
#3

Quels risques sont associés à l'association avec d'autres médicaments ?

L'association avec des opioïdes ou l'alcool augmente le risque de dépression respiratoire.
Interactions médicamenteuses Benzodiazépines
#4

Les benzodiazépines peuvent-elles provoquer des chutes chez les personnes âgées ?

Oui, elles augmentent le risque de chutes et de fractures chez les personnes âgées.
Chutes Benzodiazépines
#5

Quels effets à long terme sur la mémoire sont observés ?

L'usage prolongé peut entraîner des troubles de la mémoire et des difficultés d'apprentissage.
Troubles de la mémoire Benzodiazépines

Facteurs de risque 5

#1

Quels facteurs augmentent le risque de dépendance ?

Les antécédents de troubles mentaux et l'usage prolongé augmentent le risque de dépendance.
Facteurs de risque Benzodiazépines
#2

Comment l'âge influence-t-il l'usage des benzodiazépines ?

Les personnes âgées sont plus susceptibles de subir des effets secondaires et des complications.
Âge Benzodiazépines
#3

Quel rôle joue l'environnement social dans l'usage ?

Un environnement stressant ou un manque de soutien social peut augmenter l'usage des benzodiazépines.
Environnement social Benzodiazépines
#4

Les antécédents familiaux influencent-ils l'usage ?

Oui, des antécédents familiaux de dépendance peuvent augmenter le risque d'usage problématique.
Antécédents familiaux Benzodiazépines
#5

Comment les troubles de santé mentale affectent-ils l'usage ?

Les personnes avec des troubles de santé mentale sont plus susceptibles d'utiliser des benzodiazépines.
Troubles mentaux Benzodiazépines
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benzodiazépines ?\nQuels conseils donner aux patients sur l'utilisation des benzodiazépines ?\nComment surveiller l'utilisation des benzodiazépines ?\nQuelles stratégies non médicamenteuses peuvent aider ?\nComment sensibiliser sur les risques des benzodiazépines ?", "url": "https://questionsmedicales.fr/mesh/D001569?mesh_terms=Analgesics,+Opioid#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Benzodiazépines", "description": "Comment traiter une dépendance aux benzodiazépines ?\nQuelles alternatives existent aux benzodiazépines pour l'anxiété ?\nComment réduire progressivement l'utilisation des benzodiazépines ?\nQuels médicaments peuvent aider à gérer le sevrage ?\nQuelle est la durée recommandée pour l'utilisation des benzodiazépines ?", "url": "https://questionsmedicales.fr/mesh/D001569?mesh_terms=Analgesics,+Opioid#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Benzodiazépines", "description": "Quelles complications peuvent survenir avec l'usage prolongé ?\nComment les benzodiazépines affectent-elles la santé mentale ?\nQuels risques sont associés à l'association avec d'autres médicaments ?\nLes benzodiazépines peuvent-elles provoquer des chutes chez les personnes âgées ?\nQuels effets à long terme sur la mémoire sont observés ?", "url": "https://questionsmedicales.fr/mesh/D001569?mesh_terms=Analgesics,+Opioid#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Benzodiazépines", "description": "Quels facteurs augmentent le risque de dépendance ?\nComment l'âge influence-t-il l'usage des benzodiazépines ?\nQuel rôle joue l'environnement social dans l'usage ?\nLes antécédents familiaux influencent-ils l'usage ?\nComment les troubles de santé mentale affectent-ils l'usage ?", "url": "https://questionsmedicales.fr/mesh/D001569?mesh_terms=Analgesics,+Opioid#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dépendance aux benzodiazépines ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur l'évaluation des symptômes et l'historique d'utilisation des médicaments." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour évaluer l'usage des benzodiazépines ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de dépistage de drogues et des évaluations psychologiques peuvent être utilisés." } }, { "@type": "Question", "name": "Quels critères DSM sont utilisés pour le diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Les critères DSM-5 incluent l'usage excessif et les symptômes de sevrage." } }, { "@type": "Question", "name": "Comment évaluer l'efficacité d'un traitement par benzodiazépines ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "L'efficacité est évaluée par la réduction des symptômes d'anxiété ou d'insomnie." } }, { "@type": "Question", "name": "Quels signes indiquent une surdose de benzodiazépines ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Les signes incluent confusion, somnolence excessive et difficultés respiratoires." } }, { "@type": "Question", "name": "Quels sont les effets secondaires courants des benzodiazépines ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les effets secondaires incluent somnolence, vertiges et troubles de la mémoire." } }, { "@type": "Question", "name": "Comment reconnaître une réaction allergique aux benzodiazépines ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Les réactions allergiques peuvent se manifester par éruptions cutanées et démangeaisons." } }, { "@type": "Question", "name": "Quels symptômes indiquent un sevrage des benzodiazépines ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes de sevrage incluent anxiété, insomnie et tremblements." } }, { "@type": "Question", "name": "Les benzodiazépines provoquent-elles des troubles cognitifs ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles peuvent entraîner des troubles de la mémoire et de la concentration." } }, { "@type": "Question", "name": "Quels symptômes peuvent nécessiter une consultation médicale urgente ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes comme confusion sévère ou difficultés respiratoires nécessitent une urgence." } }, { "@type": "Question", "name": "Comment prévenir la dépendance aux benzodiazépines ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention inclut une prescription prudente et une éducation sur les risques." } }, { "@type": "Question", "name": "Quels conseils donner aux patients sur l'utilisation des benzodiazépines ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Les patients doivent être informés des risques et de l'importance de suivre les prescriptions." } }, { "@type": "Question", "name": "Comment surveiller l'utilisation des benzodiazépines ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Les médecins doivent effectuer des suivis réguliers pour évaluer l'usage et les effets." } }, { "@type": "Question", "name": "Quelles stratégies non médicamenteuses peuvent aider ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Des techniques comme la méditation et l'exercice physique peuvent réduire l'anxiété." } }, { "@type": "Question", "name": "Comment sensibiliser sur les risques des benzodiazépines ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Des campagnes d'information et des ateliers peuvent sensibiliser le public aux risques." } }, { "@type": "Question", "name": "Comment traiter une dépendance aux benzodiazépines ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement inclut une désintoxication supervisée et une thérapie comportementale." } }, { "@type": "Question", "name": "Quelles alternatives existent aux benzodiazépines pour l'anxiété ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Les alternatives incluent les antidépresseurs et les thérapies cognitivo-comportementales." } }, { "@type": "Question", "name": "Comment réduire progressivement l'utilisation des benzodiazépines ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "La réduction doit être progressive, sous supervision médicale pour éviter le sevrage." } }, { "@type": "Question", "name": "Quels médicaments peuvent aider à gérer le sevrage ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Des médicaments comme le diazépam peuvent être utilisés pour atténuer les symptômes de sevrage." } }, { "@type": "Question", "name": "Quelle est la durée recommandée pour l'utilisation des benzodiazépines ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "L'utilisation est généralement recommandée pour une courte durée, souvent moins de 4 semaines." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec l'usage prolongé ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "L'usage prolongé peut entraîner des troubles cognitifs et une dépendance sévère." } }, { "@type": "Question", "name": "Comment les benzodiazépines affectent-elles la santé mentale ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent aggraver des troubles mentaux comme la dépression et l'anxiété." } }, { "@type": "Question", "name": "Quels risques sont associés à l'association avec d'autres médicaments ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "L'association avec des opioïdes ou l'alcool augmente le risque de dépression respiratoire." } }, { "@type": "Question", "name": "Les benzodiazépines peuvent-elles provoquer des chutes chez les personnes âgées ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles augmentent le risque de chutes et de fractures chez les personnes âgées." } }, { "@type": "Question", "name": "Quels effets à long terme sur la mémoire sont observés ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "L'usage prolongé peut entraîner des troubles de la mémoire et des difficultés d'apprentissage." } }, { "@type": "Question", "name": "Quels facteurs augmentent le risque de dépendance ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les antécédents de troubles mentaux et l'usage prolongé augmentent le risque de dépendance." } }, { "@type": "Question", "name": "Comment l'âge influence-t-il l'usage des benzodiazépines ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Les personnes âgées sont plus susceptibles de subir des effets secondaires et des complications." } }, { "@type": "Question", "name": "Quel rôle joue l'environnement social dans l'usage ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Un environnement stressant ou un manque de soutien social peut augmenter l'usage des benzodiazépines." } }, { "@type": "Question", "name": "Les antécédents familiaux influencent-ils l'usage ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents familiaux de dépendance peuvent augmenter le risque d'usage problématique." } }, { "@type": "Question", "name": "Comment les troubles de santé mentale affectent-ils l'usage ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Les personnes avec des troubles de santé mentale sont plus susceptibles d'utiliser des benzodiazépines." } } ] } ] }
Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale

Validation scientifique effectuée le 29/04/2025

Contenu vérifié selon les dernières recommandations médicales

En savoir plus sur Dr Menir

Sous-catégories

24 au total
└─

Alprazolam

Alprazolam D000525 - D03.633.100.079.080.030
└─

Benzodiazépinones

Benzodiazepinones D001570 - D03.633.100.079.080.070
└─

Chlordiazépoxyde

Chlordiazepoxide D002707 - D03.633.100.079.080.150
└─

Clobazam

Clobazam D000078306 - D03.633.100.079.080.165
└─

Clorazépate dipotassique

Clorazepate Dipotassium D003009 - D03.633.100.079.080.180
└─

Estazolam

Estazolam D004949 - D03.633.100.079.080.250
└─

Médazépam

Medazepam D008472 - D03.633.100.079.080.550
└─

Midazolam

Midazolam D008874 - D03.633.100.079.080.575
└─

Olanzapine

Olanzapine D000077152 - D03.633.100.079.080.738
└─

Triazolam

Triazolam D014229 - D03.633.100.079.080.900
└─└─

Bromazépam

Bromazepam D001960 - D03.633.100.079.080.070.110
└─└─

Clonazépam

Clonazepam D002998 - D03.633.100.079.080.070.150
└─└─

Dévazépide

Devazepide D020109 - D03.633.100.079.080.070.200
└─└─

Diazépam

Diazepam D003975 - D03.633.100.079.080.070.216
└─└─

Flumazénil

Flumazenil D005442 - D03.633.100.079.080.070.305
└─└─

Flunitrazépam

Flunitrazepam D005445 - D03.633.100.079.080.070.320
└─└─

Flurazépam

Flurazepam D005479 - D03.633.100.079.080.070.348
└─└─

Lorazépam

Lorazepam D008140 - D03.633.100.079.080.070.450
└─└─

Nitrazépam

Nitrazepam D009567 - D03.633.100.079.080.070.565
└─└─

Oxazépam

Oxazepam D010076 - D03.633.100.079.080.070.663
└─└─

Pirenzépine

Pirenzepine D010890 - D03.633.100.079.080.070.750
└─└─

Prazépam

Prazepam D011222 - D03.633.100.079.080.070.784
└─└─

Témazépam

Temazepam D013693 - D03.633.100.079.080.070.880
└─└─└─

Nordazépam

Nordazepam D003708 - D03.633.100.079.080.070.216.500

Auteurs principaux

Babette Bais

2 publications dans cette catégorie

Affiliations :
  • Department of Psychiatry, Erasmus University Medical Centre Rotterdam, Rotterdam, Netherlands.
Publications dans "Benzodiazépines" :

Steven Wright

2 publications dans cette catégorie

Affiliations :
  • Former medical director of the Alliance for Benzodiazepine Best Practices, Portland, OR, a nonprofit resource for physicians and patients.
Publications dans "Benzodiazépines" :

Christine Champion

2 publications dans cette catégorie

Affiliations :
  • Université Lyon 1, Lyon, France, Hôpital des Charpennes, Hospices Civils de Lyon, Lyon, France.
Publications dans "Benzodiazépines" :

Teddy Novais

2 publications dans cette catégorie

Affiliations :
  • Université Lyon 1, Lyon, France, Service pharmaceutique, Hôpital des Charpennes, Hospices Civils de Lyon, Lyon, France, Université Claude-Bernard Lyon 1, Research on Healthcare Performance (RESHAPE), Inserm U1290, Lyon, France.
Publications dans "Benzodiazépines" :

Jean-Michel Dorey

2 publications dans cette catégorie

Affiliations :
  • Université Lyon 1, Lyon, France, Centre Hospitalier Le Vinatier, Bron, France.
Publications dans "Benzodiazépines" :

Pierre Krolak-Salmon

2 publications dans cette catégorie

Affiliations :
  • Université Lyon 1, Lyon, France, Inserm U1028, CNRS UMR5292, Centre de recherche en neurosciences de Lyon, Lyon, France, Hôpital des Charpennes, Hospices Civils de Lyon, Lyon, France, Centre Mémoire Ressource et Recherche de Lyon (CMRR), Hôpital des Charpennes, Hospices Civils de Lyon, Lyon, France.
Publications dans "Benzodiazépines" :

Alexis Lepetit

2 publications dans cette catégorie

Affiliations :
  • Hôpital des Charpennes, Hospices Civils de Lyon, Lyon, France, CNRS UMR 5229, Institut des Sciences Cognitives Marc-Jeannerod, Team "Neuroplasticity in Parkinson's disease".
Publications dans "Benzodiazépines" :

Richard Balon

2 publications dans cette catégorie

Affiliations :
  • Department of Psychiatry and Behavioral Neurosciences and Anesthesiology, Wayne State University, Detroit, MI, USA. rbalon@wayne.edu.
Publications dans "Benzodiazépines" :

Vladan Starcevic

2 publications dans cette catégorie

Affiliations :
  • Discipline of Psychiatry, Nepean Clinical School, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Publications dans "Benzodiazépines" :

Md Yeunus Mian

2 publications dans cette catégorie

Affiliations :
  • Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
  • Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Dishary Sharmin

2 publications dans cette catégorie

Affiliations :
  • Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
  • Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Prithu Mondal

2 publications dans cette catégorie

Affiliations :
  • Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
  • Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Jawad Bin Belayet

2 publications dans cette catégorie

Affiliations :
  • Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
  • Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Publications dans "Benzodiazépines" :

M Mahmun Hossain

2 publications dans cette catégorie

Affiliations :
  • Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
  • Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Paul McCusker

2 publications dans cette catégorie

Affiliations :
  • Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Kaetlyn T Ryan

2 publications dans cette catégorie

Affiliations :
  • Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Alexander Y Fedorov

2 publications dans cette catégorie

Affiliations :
  • UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Heather A Green

2 publications dans cette catégorie

Affiliations :
  • UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Spencer S Ericksen

2 publications dans cette catégorie

Affiliations :
  • UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Mostafa Zamanian

2 publications dans cette catégorie

Affiliations :
  • Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Publications dans "Benzodiazépines" :

Sources (8589 au total)

Trends in opioid analgesic utilisation among people with a history of opioid dependence.

01 09 2022
DOI: 10.1016/j.drugalcdep.2022.109548 PMID: 35841733

We aimed to characterise opioid analgesic utilisation over a 16-year period among a cohort of people with a history of opioid dependence, comparing rates of use in and out of opioid agonist treatment ... Retrospective cohort study in New South Wales, Australia, including 28,891 people with documented opioid dependence initiating opioid analgesics between July 2003 and December 2018. Linked administrat... At initiation, 43.7% of the cohort were enrolled in OAT. The most commonly initiated opioid was codeine (including combinations with paracetamol; 67.8%), and 49.6% of the cohort were dispensed a psych... People with opioid dependence had high rates of recent psychotropic medicine utilisation and current OAT enrolment at the time of opioid analgesic initiation. OAT was associated with a significant red...

Analgesics, Opioid Codeine Drug Prescriptions Humans Morphine +2 autres

State prescribing cap laws' association with opioid analgesic prescribing and opioid overdose.

01 11 2022
DOI: 10.1016/j.drugalcdep.2022.109626 PMID: 36115221

In response to the role of opioid prescribing in the U.S. opioid crisis, states have enacted laws intended to curb high risk opioid prescribing practices. This study assessed the effects of state pres... We identified 1,414,908 adults from a large U.S. administrative insurance claims database. Treatment states included 32 states that implemented a prescribing cap law between 2017 and 2019. Comparison ... State opioid prescribing cap laws were not associated with changes in the proportion of people receiving opioid analgesic prescriptions, the dose or duration of opioid prescriptions, or opioid overdos... State opioid prescribing cap laws did not appear to impact outcomes related to opioid analgesic prescribing or opioid overdose. These findings are potentially due to the limited scope of these laws, w...

Adult Humans United States Analgesics, Opioid Opiate Overdose +4 autres

Survey of Opioid Risk Tool Among Cancer Patients Receiving Opioid Analgesics.

13 Jun 2022
DOI: 10.3346/jkms.2022.37.e185 PMID: 35698838

The risk of opioid-related aberrant behavior (OAB) in Korean cancer patients has not been previously evaluated. The purpose of this study is to investigate the Opioid Risk Tool (ORT) in Korean cancer ... Data were obtained from a multicenter, cross-sectional, nationwide observational study regarding breakthrough cancer pain. The study was conducted in 33 South Korean institutions from March 2016 to De... We analyzed ORT results of 946 patients. Only one patient in each sex (0.2%) was classified as high risk for OAB. Moderate risk was observed in 18 males (3.3%) and in three females (0.7%). Scores abov... The score of ORT was very low in cancer patients receiving strong opioids for analgesia. Higher pain intensity may associate with positive response to one or more ORT item....

Alcoholism Analgesics, Opioid Cross-Sectional Studies Female Humans +3 autres

A Comparison of Prehospital Pediatric Analgesic Use of Ketamine and Opioids.

2023
DOI: 10.1080/10903127.2023.2183295 PMID: 36857195

Ketamine is an opioid-alternative used for analgesia in the prehospital setting. There are knowledge gaps regarding its use during emergency medical services (EMS) encounters for pediatric patients. O... This was a retrospective review of 9-1-1 EMS records of injured pediatric patients (≤17 years of age) who received ketamine or opioids for analgesia using the ESO Data Collaborative (calendar years 20... Overall, 9,223 patients were included, 190 (2.1%) received ketamine and 9,033 (97.9%) received opioids. Mean age in years was 12.8 [SD 4.0] for ketamine and 12.7 [SD 4.0] for opioids. Patients in both... We identified similar high rates of pain reduction and rare adverse events among pediatric patients who received ketamine or opioids. A greater pain reduction was noted among patients administered ket...

Humans Child Ketamine Analgesics, Opioid Emergency Medical Services +3 autres

Opioid and non-opioid analgesic prescribing practices for pediatric adenotonsillectomy in a tertiary care center.

Dec 2022
DOI: 10.1016/j.ijporl.2022.111337 PMID: 36302324

The U.S. is in an opioid epidemic with greater than 40,000 deaths annually. Pediatric adenotonsillectomy is one of the most common and painful otolaryngology surgeries performed, often associated with... To understand postoperative prescribing practices of adenotonsillectomy in a tertiary care institution and associated postoperative emergency department (ED) visits.... Descriptive analysis of retrospective cohort data.... Tertiary academic healthcare institution.... Pediatric patients <18yo undergoing adenotonsillectomy between 2013 and 2016.... Postoperative analgesic regimens assessed including opioid and non-opioid analgesic prescriptions upon discharge from tonsillectomy surgery.... Main outcomes included ED presentation within 30-days of surgery and reoperation. Secondary outcomes included reason for ED presentation and relation to prescribed analgesics. Data was analyzed betwee... 200 patients were included in the study with 69% prescribed opioids, and 51% prescribed non-opioid analgesics. Number of opioid doses ranged widely with a median of 37 (Q1, Q3: 0, 62). There were no d...

Child Humans Analgesics, Opioid Analgesics, Non-Narcotic Tonsillectomy +6 autres

Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns.

01 08 2022
DOI: 10.1001/jamanetworkopen.2022.28588 PMID: 36001312

Prescription opioids are often used during pregnancy even though they are associated with neonatal opioid withdrawal syndrome (NOWS). Most studies of adverse outcomes of opioid use for pain have asses... To compare the risk of NOWS across common types of opioids when prescribed as monotherapy during the last 3 months of pregnancy.... This cohort study analyzed administrative claims data of Medicaid-insured mothers and newborns in 46 states and Washington DC from January 1, 2000, through December 31, 2014. Participants were mothers... Different types of opioid medications were compared by agonist strength (strong vs weak) and half-life (medium vs short and long vs short) of the opioid active ingredient.... The primary outcome was NOWS, which was identified using an International Classification of Diseases, Ninth Revision, Clinical Modification diagnostic code in the 30 days after delivery. Relative risk... The cohort comprised 48 202 opioid-exposed pregnancies with live newborns. A total of 1069 neonates (2.2%) had NOWS and 559 (1.2%) had severe NOWS. Opioid exposure during pregnancy included 16 202 pre... Results of this study show higher risk of NOWS and severe NOWS among neonates with in utero exposure to strong agonists and long half-life prescription opioids. Information on the opioid-specific risk...

Adult Analgesics, Opioid Codeine Cohort Studies Female +15 autres