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"description": "Comment diagnostiquer une carence en biotine ?\nQuels sont les signes cliniques d'une carence ?\nLes tests génétiques sont-ils utiles ?\nQuelle est la méthode de dépistage recommandée ?\nPeut-on diagnostiquer par des symptômes seuls ?",
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"name": "Comment diagnostiquer une carence en biotine ?",
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"text": "Le diagnostic se fait par des tests sanguins mesurant les niveaux de biotine."
}
},
{
"@type": "Question",
"name": "Quels sont les signes cliniques d'une carence ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes incluent fatigue, dépression, éruptions cutanées et perte de cheveux."
}
},
{
"@type": "Question",
"name": "Les tests génétiques sont-ils utiles ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent identifier des troubles métaboliques liés à la biotine."
}
},
{
"@type": "Question",
"name": "Quelle est la méthode de dépistage recommandée ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un dosage de la biotine dans le sérum est la méthode standard de dépistage."
}
},
{
"@type": "Question",
"name": "Peut-on diagnostiquer par des symptômes seuls ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les symptômes doivent être confirmés par des tests de laboratoire."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une carence en biotine ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent fatigue, dépression, éruptions cutanées et troubles neurologiques."
}
},
{
"@type": "Question",
"name": "La perte de cheveux est-elle un symptôme ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la perte de cheveux est un symptôme courant d'une carence en biotine."
}
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{
"@type": "Question",
"name": "Y a-t-il des symptômes digestifs ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des symptômes comme des nausées et des douleurs abdominales peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les troubles de l'humeur sont-ils liés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la dépression et l'irritabilité peuvent être des symptômes de carence."
}
},
{
"@type": "Question",
"name": "Les éruptions cutanées sont-elles fréquentes ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des éruptions cutanées, souvent rouges et squameuses, sont fréquentes."
}
},
{
"@type": "Question",
"name": "Comment prévenir une carence en biotine ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée incluant des aliments riches en biotine aide à prévenir la carence."
}
},
{
"@type": "Question",
"name": "Les personnes à risque doivent-elles se supplémenter ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes à risque, comme les femmes enceintes, devraient envisager des suppléments."
}
},
{
"@type": "Question",
"name": "Les régimes restrictifs augmentent-ils le risque ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les régimes très restrictifs peuvent augmenter le risque de carence en biotine."
}
},
{
"@type": "Question",
"name": "Les antibiotiques affectent-ils la biotine ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains antibiotiques peuvent perturber l'absorption de la biotine."
}
},
{
"@type": "Question",
"name": "Les aliments transformés sont-ils un risque ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les aliments transformés peuvent être pauvres en biotine et augmenter le risque."
}
},
{
"@type": "Question",
"name": "Comment traiter une carence en biotine ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement consiste en des suppléments de biotine et des modifications alimentaires."
}
},
{
"@type": "Question",
"name": "Quels aliments sont riches en biotine ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les œufs, les noix, le soja et les légumes à feuilles vertes sont riches en biotine."
}
},
{
"@type": "Question",
"name": "Les suppléments sont-ils nécessaires ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, dans les cas de carence, des suppléments peuvent être nécessaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires aux suppléments ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires sont rares, mais peuvent inclure des troubles gastro-intestinaux."
}
},
{
"@type": "Question",
"name": "Combien de temps dure le traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut durer plusieurs semaines, selon la gravité de la carence."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles neurologiques et des problèmes cutanés graves."
}
},
{
"@type": "Question",
"name": "La carence peut-elle affecter le développement ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, chez les enfants, une carence peut affecter le développement physique et mental."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une carence prolongée peut entraîner des problèmes de santé chroniques."
}
},
{
"@type": "Question",
"name": "Les troubles mentaux sont-ils possibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles mentaux comme la dépression peuvent être exacerbés par une carence."
}
},
{
"@type": "Question",
"name": "Les complications cutanées sont-elles fréquentes ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications cutanées comme des infections peuvent survenir en cas de carence."
}
},
{
"@type": "Question",
"name": "Qui est à risque de carence en biotine ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes ayant une alimentation déséquilibrée ou des troubles digestifs sont à risque."
}
},
{
"@type": "Question",
"name": "Les femmes enceintes sont-elles plus à risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes enceintes ont des besoins accrus en biotine et peuvent être à risque."
}
},
{
"@type": "Question",
"name": "Les personnes âgées sont-elles vulnérables ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées peuvent avoir des carences en raison d'une absorption réduite."
}
},
{
"@type": "Question",
"name": "Les végétariens sont-ils à risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les végétariens peuvent être à risque s'ils ne consomment pas d'aliments riches en biotine."
}
},
{
"@type": "Question",
"name": "Les personnes avec des troubles métaboliques sont-elles à risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains troubles métaboliques peuvent affecter l'absorption de la biotine."
}
}
]
}
]
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Emerging evidence indicated that depression is currently one of the most burdensome diseases worldwide, and it can lead to a variety of functional physical impairments. However, the studies estimated ...
A cross-sectional analysis was performed using the data from the National Health and Nutrition Examination Survey conducted from 2007 to 2012. In the 12,502 adults aged 20-80 years, weighted linear re...
The final results were reached after adjusting for various confounding factors. In the stratification analysis of subgroups divided by age, depression was significantly negatively correlated with FT4,...
This study confirmed a significant correlation between depressive and thyroid function and it varied among different genders or age. In the future, more prospective studies are needed to reveal these ...
Thyroid disorders have been reported in hypercortisolism patients. Endogenous Cushing's syndrome (CS) potentially complicates its metabolic sequelae. We investigated thyroid function in CS patients to...
In this cross-sectional study, we screened CS patients from 2016 to 2019 at our hospital. Patient demographic, medical history, and laboratory data were collected. Additionally, we performed a meta-an...
Among 129 CS patients, 48.6% had triiodothyronine (TT3), 27.9% had thyroxine (TT4), 24.6% had free T3 (FT3), 27.7% had free T4 (FT4), and 6.2% had thyroid-stimulating hormone (TSH) levels below the re...
Thyroid hormone levels are significantly correlated with cortisol levels and are impaired in patients with CS. However, the physiological adaptation and pathological conditions need further study....
This study aims to analyze the relationship between papillary thyroid carcinoma (PTC) and various factors....
The study involved two groups-PTC patients and non-PTC controls. We utilized binary logistic regression and Least Absolute Shrinkage and Selection Operator (Lasso) regression for variable selection an...
PTC patients exhibited higher body mass index (BMI) (23.71 vs. 22.66, p<0.05) and TSH levels (3.38 vs. 1.59, p<0.05). Urinary iodine concentration (UIC) was an independent predictor of PTC (OR=1.005, ...
UIC may be an independent predictor of PTC, and TSH levels have some diagnostic value for identifying PTC....
Normal thyroid status throughout pregnancy is important for both maternal and fetal health. Despite the bulk of contemporary research honing on thyroid function in gestation and the relevant disorders...
This article analyzes the adaptation of the thyroid gland to gestational physiological changes and attempts to explain the effect of several factors on thyroid function in pregnancy. It also stresses ...
Appropriate strategies for diagnosing and treating thyroid disease in pregnancy are important. Laboratory thyroid testing plays a leading role, but test results should be interpreted with caution. Giv...
The thyroid function test (free triiodothyronine [FT3], free thyroxine [FT4], and thyroid-stimulating hormone [TSH]) is one of the key determinant of glucose homeostasis by regulating the balance of i...
A cross-sectional study was conducted in Saad Abuelela Hospital, Khartoum-Sudan, from January to April 2021. Obstetric/sociodemographic characteristics were gathered through questionnaires. Serum TSH,...
In total, the study included 127 pregnant women with a median age of 27.0 years (interquartile range [IQR] 23.0‒31.2) and a median gestational (IQR) age of 25.0 (IQR 25.0‒27.0) weeks. The medians (IQR...
This study indicated that FT3 has positive correlation with HOMA-IR, while FT4 has negative correlation among healthy pregnant women without a history of thyroid dysfunction. This may indicate screeni...
Numerous organs, including the thyroid gland, depend on vitamin D to function normally. Insufficient levels of serum 25-hydroxyvitamin D [25(OH)D] are seen as a potential factor contributing to the em...
We conducted a two-sample MR analysis utilizing summary data from the most extensive genome-wide association studies (GWAS) of serum 25(OH)D concentration (n = 443,734 and 417,580), thyroid-stimulatin...
The IVW, as well as MR Egger and CAUSE analysis, showed a suggestive causal effect of 25(OH)D concentration on high TSH. Each 1 SD increase in serum 25(OH)D concentration was associated with a 12% dec...
Our results support a suggestive causal effect which was negative in direction across all methods used, meaning that higher genetically predicted vitamin D concentration possibly lowers the odds of ha...
The ongoing COVID-19 pandemic calls for extensive research on various medical topics. Since the beginning of the pandemic, multiple studies investigated the impact of SARS CoV-2 on thyroid function. H...
The aim of the study was to investigate thyroid function test (TFT) results and anti-thyroid antibody titers in acutely infected COVID-19 patients, as well as the changes in TFT and autoantibody resul...
A total of 163 adult COVID-19 patients and 124 COVID-19 survivors were evaluated in terms of TFT (thyroid stimulating hormone [TSH], free triiodothyronine [fT3], and free thyroxine [fT4]) and anti-thy...
Thyroid dysfunction was noted in 56.4% of patients on admission, including the non-thyroidal illness syndrome (NTIS) in most cases. Presence vs. absence of thyroid dysfunction on admission was associa...
This is one of the few studies to evaluate TFT and autoantibodies over a 6-month period after recovery from COVID-19. The presence of emergent or persistent subclinical hypothyroidism and the signific...
Laboratory plays important part in screening, diagnosis, and management of thyroid disorders. The aim of this study was to estimate current laboratory preanalytical, analytical and postanalytical prac...
Working Group for Laboratory Endocrinology of the Croatian Society of Medical Biochemistry and Laboratory Medicine designed a questionnaire with 27 questions and statements regarding practices and pro...
Fifty-three participants returned the questionnaire. Response rate varied depending on question, yielding a total survey response rate of 46-48%. All respondents perform thyroid stimulating hormone (T...
This survey showed current practices and policies in Croatian laboratories regarding thyroid testing. The results identified some critical spots and will serve as a foundation in creating national gui...
Hashimoto's thyroiditis (HT) is the leading cause of hypothyroidism, affecting mainly the female population. Many patients with HT have metabolic disorders and nutritional deficiencies. The aim of thi...