questionsmedicales.fr
États, signes et symptômes pathologiques
Processus pathologiques
Caractéristiques de la maladie
Maladie chronique
Candidose mucocutanée chronique
Candidose mucocutanée chronique : Questions médicales fréquentes
Diagnostic
5
Candidose
Diagnostic médical
Culture fongique
Candidose
Infections fongiques
Candidose
Traitements
5
Traitement topique
Candidose
Durée du traitement
Candidose
Traitements alternatifs
Candidose
Complications
5
Candidose
Infections systémiques
Immunodépression
Candidose
Facteurs de risque
5
Facteurs de risque
Candidose
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"text": "Oui, les symptômes peuvent varier selon qu'ils affectent la peau ou les muqueuses."
}
},
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"@type": "Question",
"name": "Y a-t-il des symptômes systémiques associés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Généralement, la candidose mucocutanée est localisée sans symptômes systémiques."
}
},
{
"@type": "Question",
"name": "Les lésions sont-elles contagieuses ?",
"position": 10,
"acceptedAnswer": {
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"text": "Non, la candidose mucocutanée n'est pas contagieuse entre individus."
}
},
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"@type": "Question",
"name": "Comment prévenir la candidose mucocutanée ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une bonne hygiène et garder la peau sèche aide à prévenir l'infection."
}
},
{
"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle dans la prévention ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut renforcer le système immunitaire et prévenir les infections."
}
},
{
"@type": "Question",
"name": "Les vêtements peuvent-ils influencer la candidose ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des vêtements serrés et en matières synthétiques peuvent favoriser l'humidité."
}
},
{
"@type": "Question",
"name": "Les probiotiques sont-ils utiles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les probiotiques peuvent aider à rétablir l'équilibre microbien et prévenir les infections."
}
},
{
"@type": "Question",
"name": "Faut-il éviter certains médicaments ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains antibiotiques peuvent favoriser la candidose, leur usage doit être réfléchi."
}
},
{
"@type": "Question",
"name": "Quels traitements sont efficaces contre la candidose ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antifongiques topiques et systémiques sont utilisés pour traiter la candidose."
}
},
{
"@type": "Question",
"name": "Les traitements topiques sont-ils suffisants ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Pour les cas légers, les traitements topiques peuvent suffire, mais pas toujours."
}
},
{
"@type": "Question",
"name": "Combien de temps dure le traitement ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La durée du traitement varie, mais elle est généralement de plusieurs semaines."
}
},
{
"@type": "Question",
"name": "Des traitements alternatifs existent-ils ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des traitements naturels comme l'huile de coco peuvent aider, mais peu de preuves."
}
},
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"@type": "Question",
"name": "Les récidives sont-elles fréquentes ?",
"position": 20,
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}
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"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
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"text": "Des infections secondaires et des lésions cutanées chroniques peuvent se développer."
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"@type": "Question",
"name": "La candidose peut-elle affecter d'autres organes ?",
"position": 22,
"acceptedAnswer": {
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"text": "Dans les cas graves, la candidose peut se propager et affecter d'autres organes."
}
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{
"@type": "Question",
"name": "Y a-t-il un risque d'infection systémique ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes immunodéprimées sont à risque d'infections systémiques graves."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles fréquentes ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications sont rares mais peuvent survenir, surtout sans traitement approprié."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi médical régulier et un traitement approprié sont essentiels pour gérer les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'immunodépression, le diabète et l'utilisation prolongée d'antibiotiques."
}
},
{
"@type": "Question",
"name": "Le diabète influence-t-il la candidose ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète mal contrôlé augmente le risque de candidose en raison de l'hyperglycémie."
}
},
{
"@type": "Question",
"name": "Les femmes sont-elles plus à risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes sont plus susceptibles de développer des candidoses, notamment vaginales."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes âgées et les jeunes enfants sont plus vulnérables aux infections fongiques."
}
},
{
"@type": "Question",
"name": "Le stress peut-il aggraver la candidose ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut affaiblir le système immunitaire et favoriser les infections fongiques."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 08/02/2025
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
Affiliations :
St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, 10065, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015, Paris, France.
Howard Hughes Medical Institute, New York, NY, USA.
7 publications dans cette catégorie
Affiliations :
St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, 10065, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015, Paris, France.
5 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
5 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
4 publications dans cette catégorie
Affiliations :
Department of Oral Medicine, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, 22 ZhongguancunNandajie, Haidian District, Beijing, 100081, People's Republic of China.
Publications dans "Candidose mucocutanée chronique" :
4 publications dans cette catégorie
Affiliations :
Department of Oral Medicine, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, 22 ZhongguancunNandajie, Haidian District, Beijing, 100081, People's Republic of China. yzhimin96@163.com.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, 10065, USA.
Section of Immunology, Rheumatology, and Allergy, Department of Pediatrics, Hsinchu Mackay Memorial Hospital, Hsinchu City, Taiwan.
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
3 publications dans cette catégorie
Affiliations :
Division of Infectious Diseases, University of Texas Health Medical School, Houston, Texas.
Publications dans "Candidose mucocutanée chronique" :
2 publications dans cette catégorie
Affiliations :
St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, 10065, USA.
Publications dans "Candidose mucocutanée chronique" :
2 publications dans cette catégorie
Affiliations :
Department of Oral Medicine, Dental Institute, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Publications dans "Candidose mucocutanée chronique" :
2 publications dans cette catégorie
Affiliations :
Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, USA.
Publications dans "Candidose mucocutanée chronique" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, Shandong Province, People's Republic of China.
Publications dans "Candidose mucocutanée chronique" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, Shandong Province, People's Republic of China.
Department of Dermatology, Jining No. 1 People's Hospital, Jining, Shandong Province, People's Republic of China.
Publications dans "Candidose mucocutanée chronique" :
2 publications dans cette catégorie
Affiliations :
Hiroshima University Graduate School of Biomedical and Health Sciences.
Publications dans "Candidose mucocutanée chronique" :
Patients with STAT1 gain-of-function (GOF) mutations suffer from an inborn error of immunity hallmarked by chronic mucocutaneous candidiasis (CMC). The pathogenesis behind this complex and heterogeneo...
Heterozygous STAT1 Gain-of-Function (GOF) mutations are the most common cause of chronic mucocutaneous candidiasis (CMC) among Inborn Errors of Immunity. Clinically, these mutations manifest as a broa...
We analyzed clinical presentations, cellular phenotypes, and functional impacts in five Taiwanese patients with STAT1 GOF....
We identified two novel GOF mutations in 5 patients from 2 Taiwanese families, presenting with symptoms of CMC, late-onset rosacea, and autoimmunity. The enhanced phosphorylation and delayed dephospho...
Our study provides the first comprehensive clinical and molecular characteristics in STAT1 GOF patient in Taiwan and highlights the dysregulated T and B cells subsets which may hinge the autoimmunity ...
The aim of this study was to characterize clinical effects and biomarkers in three patients with chronic mucocutaneous candidiasis (CMC) caused by gain-of-function (GOF) mutations in the STAT1 gene du...
Mass cytometry (CyTOF) was used to characterize mononuclear leukocyte populations and Olink assay to quantify 265 plasma proteins. Flow-cytometric Assay for Specific Cell-mediated Immune-response in A...
Overall, JAK inhibitors improved clinical symptoms of CMC, but caused side effects in two patients. Absolute numbers of neutrophils, T cells, B cells, and NK cells were sustained during baricitinib tr...
The clinical effect of JAK inhibitor treatment of CMC is promising. Several biological variables were altered during baricitinib treatment demonstrating that lymphocytes, NK cells, monocytes, and eosi...
To further elucidate the clinical, immunological and genetic features of chronic mucocutaneous candidiasis (CMC) due to STAT1 GOF mutation in the Chinese population....
Clinical data for a proband were collected, and pedigree analyses were performed. Whole-exome sequencing and targeted Sanger sequencing were conducted to explore genetic factors of a Chinese pedigree ...
An autosomal dominant CMC pedigree was identified, and both the proband and his father had mucocutaneous Candida infections without involvement of other systems. A rare mutation (c.T1175C) in STAT1 wa...
STAT1 GOF mutation at c.T1175C (p.M392T) may lead to mucocutaneous Candida infections and an increase in serum IFN-α. T385M in the DNA-binding domain is the most common STAT1 GOF mutation found in the...
Chronic mucocutaneous candidiasis (CMC) is characterized by recurrent or persistent infections with...
Chronic mucocutaneous candidiasis (CMC) is a rare infectious skin disease. This study reported a case of CMC in a child with clinical manifestations of oral mucosal leukoplakia and erythema and crust-...
Chronic mucocutaneous candidiasis (CMC) is characterized by recurrent or persistent infections with...
Chronic Mucocutaneous Candidiasis (CMC) is a rare immunodeficiency disease characterized by chronic or recurrent superficial...
A 30-year-old man presented with oral candidiasis and a history of lung abscess. He experienced recurring oral and skin candidiasis in childhood but spent long periods without any infections. Therefor...
Inborn errors of the IL-17A/F-responsive pathway lead to chronic mucocutaneous candidiasis (CMC) as a predominant clinical phenotype, without other significant clinical manifestations apart from mucoc...
Flow cytometry, qPCR, RNA-sequencing, and immunoblotting were conducted, and an...
The patient presented with oral and mucocutaneous candidiasis without staphylococcal diseases since the age of three months. Genetic analysis showed that the novel duplication variant (Chr3: 9,971,476...
The clinical and cellular phenotype of the current case of AR IL-17RC deficiency supports a previous report on this rare disorder. Our newly established evaluation system will be useful for diagnosis ...