questionsmedicales.fr
Système nerveux
Système nerveux central
Encéphale
Tronc cérébral
Rhombencéphale
Métencéphale
Cervelet
Cervelet : Questions médicales fréquentes
Termes MeSH sélectionnés :
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"name": "Comment diagnostiquer une dysfonction du cervelet ?",
"position": 1,
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"text": "Un examen neurologique, des tests d'équilibre et des imageries cérébrales sont utilisés."
}
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{
"@type": "Question",
"name": "Quels tests d'imagerie sont utilisés pour le cervelet ?",
"position": 2,
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"text": "L'IRM et le scanner sont couramment utilisés pour visualiser le cervelet."
}
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"position": 3,
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"text": "Des troubles de l'équilibre, des mouvements saccadés et des difficultés de coordination."
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"@type": "Question",
"name": "Le cervelet peut-il être affecté par des maladies génétiques ?",
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"name": "Comment évaluer l'équilibre d'un patient ?",
"position": 5,
"acceptedAnswer": {
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"text": "Des tests comme le Romberg et le test de marche sur ligne droite sont utilisés."
}
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"@type": "Question",
"name": "Quels sont les symptômes d'une lésion cérébelleuse ?",
"position": 6,
"acceptedAnswer": {
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"text": "Ataxie, tremblements, vertiges et troubles de la parole peuvent survenir."
}
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"@type": "Question",
"name": "Comment se manifeste l'ataxie cérébelleuse ?",
"position": 7,
"acceptedAnswer": {
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"@type": "Question",
"name": "Les troubles de la parole sont-ils liés au cervelet ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, des difficultés d'élocution peuvent résulter d'une dysfonction cérébelleuse."
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"@type": "Question",
"name": "Qu'est-ce que le tremblement intentionnel ?",
"position": 9,
"acceptedAnswer": {
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"text": "C'est un tremblement qui se produit lors de mouvements volontaires, souvent lié au cervelet."
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"@type": "Question",
"name": "Les vertiges peuvent-ils être causés par des problèmes au cervelet ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, des troubles cérébelleux peuvent entraîner des sensations de vertige."
}
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"@type": "Question",
"name": "Comment prévenir les troubles du cervelet ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain, l'exercice régulier et l'évitement des toxines peuvent aider."
}
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{
"@type": "Question",
"name": "Les accidents peuvent-ils affecter le cervelet ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traumatismes crâniens peuvent causer des lésions au cervelet."
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"@type": "Question",
"name": "Y a-t-il des vaccins pour prévenir les infections cérébelleuses ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les vaccins contre certaines infections comme la méningite peuvent aider à prévenir."
}
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{
"@type": "Question",
"name": "L'alcool peut-il nuire au cervelet ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une consommation excessive d'alcool peut entraîner des dommages au cervelet."
}
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"@type": "Question",
"name": "Comment éviter les maladies génétiques affectant le cervelet ?",
"position": 15,
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"@type": "Answer",
"text": "Le conseil génétique peut aider à évaluer les risques pour les familles concernées."
}
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"@type": "Question",
"name": "Quels traitements existent pour les troubles du cervelet ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "La rééducation, la thérapie physique et parfois des médicaments sont utilisés."
}
},
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"@type": "Question",
"name": "La chirurgie est-elle une option pour les tumeurs cérébelleuses ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la chirurgie peut être nécessaire pour retirer des tumeurs au cervelet."
}
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{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider les symptômes cérébelleux ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments peuvent soulager les symptômes, mais ne guérissent pas la cause."
}
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{
"@type": "Question",
"name": "Comment la rééducation aide-t-elle les patients cérébelleux ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle améliore la coordination, l'équilibre et la fonction motrice par des exercices ciblés."
}
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{
"@type": "Question",
"name": "Les thérapies alternatives sont-elles efficaces pour le cervelet ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines thérapies comme l'acupuncture peuvent aider, mais les preuves sont limitées."
}
},
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"@type": "Question",
"name": "Quelles complications peuvent survenir après une lésion cérébelleuse ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles de l'équilibre, des chutes fréquentes et des difficultés de coordination."
}
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"@type": "Question",
"name": "Les troubles du cervelet peuvent-ils affecter la vie quotidienne ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent rendre les activités quotidiennes difficiles, comme marcher ou écrire."
}
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"@type": "Question",
"name": "Les patients cérébelleux risquent-ils des chutes ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, en raison de l'instabilité et des problèmes d'équilibre, le risque de chutes augmente."
}
},
{
"@type": "Question",
"name": "Les troubles cognitifs peuvent-ils être liés au cervelet ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines dysfonctions cérébelleuses peuvent entraîner des troubles cognitifs."
}
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"@type": "Question",
"name": "Les complications peuvent-elles être réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent s'améliorer avec un traitement approprié et une rééducation."
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"@type": "Question",
"name": "Quels sont les facteurs de risque pour les troubles du cervelet ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux, l'alcoolisme et les traumatismes crâniens sont des facteurs de risque."
}
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"@type": "Question",
"name": "L'âge influence-t-il les troubles du cervelet ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque de troubles cérébelleux augmente avec l'âge en raison de la dégénérescence."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes affectent-elles le cervelet ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies auto-immunes peuvent provoquer des inflammations cérébelleuses."
}
},
{
"@type": "Question",
"name": "Le stress peut-il affecter le cervelet ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut exacerber les symptômes des troubles cérébelleux."
}
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"@type": "Question",
"name": "Les infections peuvent-elles endommager le cervelet ?",
"position": 30,
"acceptedAnswer": {
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Complement-based drug discovery is undergoing a renaissance, empowered by new advances in structural biology, complement biology and drug development. Certain components of the complement pathway, par...
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The complement system constitutes an integral component of the innate immune system and plays a critical role in adaptive immunity. Activation of this system engenders the production of complement pep...
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In myelin oligodendrocyte glycoprotein IgG-associated disease (MOGAD) and aquaporin-4 IgG+ neuromyelitis optica spectrum disorder (AQP4+NMOSD), the autoantibodies are mainly composed of IgG1, and comp...
CSF-C3a, CSF-C4a, CSF-C5a, and CSF-C5b-9 levels during the acute phase before treatment in patients with MOGAD (n = 12), AQP4+NMOSD (n = 11), multiple sclerosis (MS) (n = 5), and noninflammatory neuro...
CSF-C3a and CSF-C5a levels were significantly higher in MOGAD (mean ± SD, 5,629 ± 1,079 pg/mL and 2,930 ± 435.8 pg/mL) and AQP4+NMOSD (6,017 ± 3,937 pg/mL and 2,544 ± 1,231 pg/mL) than in MS (1,507 ± ...
The complement pathway is activated in both MOGAD and AQP4+NMOSD, but MAC formation is lower in MOGAD, particularly in those with mild attacks, than in AQP4+NMOSD. These findings may have pathogenetic...
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-induced disease (COVID-19) and Gaucher disease (GD) exhibit upregulation of complement 5a (C5a) and its C5aR1 receptor, and excess synthesi...
Persistent disease is a significant issue in the management of perianal fistulas, with up to 50% of patients requiring additional treatment after surgery....
This study aimed to identify a novel prognostic modality in hopes of risk-stratifying patients for persistent disease following corrective surgery....
This was a retrospective study based on prospectively collected data using a combination of histopathology, high-throughput proteomic arrays, and ELISA-based methods....
This study used data obtained from patients who underwent corrective surgery for perianal fistulas at the University of Illinois Hospital between June 2019 and July 2020....
A cohort of 22 consecutive patients who had corrective surgery for perianal fistulas were included in this study. The patients were divided into 2 groups: those with resolving fistulas (N = 13) and th...
Nonresolving fistulas were determined by disease representation within 2 months of corrective surgery....
Serum samples from patients with persistent perianal fistulas displayed a consistent decrease in the expression of complement pathway component C5a compared with either healthy controls or patients wi...
This study was limited by its retrospective design, relatively small sample size, and single-center data analysis....
These results suggest that C5a is modestly depleted in patients with nonresolving forms of disease and traffics to the site of tissue damage and inflammation. Accordingly, serum C5a warrants continued...
ANTECEDENTES:La persistencia de la enfermedad es un problema significativo en el manejo de las fístulas perianales, presente hasta en el 50 % de los pacientes después de la cirugía y que requieren tra...
Alzheimer's disease (AD) is a common cause of dementia. Serum complement factor 5a (C5a) is exceedingly implicated in AD. We explored the role of C5a levels in AD patients of different severity....
Mild, moderate, and severe AD patients, and healthy controls were included. C5a and pro-inflammatory factor (TNF-α, IL-1β, IL-6, CRP) levels were assessed by ELISA, and cognitive function was evaluate...
Serum C5a, TNF-α, IL-1β, IL-6 and CRP levels were raised, and MMSE score was lowered in AD. Serum C5a, TNF-α, IL-1β, IL-6 and CRP levels in severe AD patients were higher than those in mild/moderate A...
Serum C5a level increased with AD severity, and its expression was positively correlated with serum pro-inflammatory factor levels, and negatively correlated with cognitive function....
Complement-mediated damage to the myocardium during acute myocardial infarction (AMI), particularly the late components of the terminal pathway (C5-convertase and C5b-9), have previously been characte...
Samples of fifty-five patients with ST-elevation myocardial infarction (STEMI) vs. healthy controls were analyzed in this study. eGC components and C5a levels were determined via ELISA; NO levels were...
Serum concentrations of eGC components and C5a were significantly increased during STEMI. Serum and solely C5a stimulation decreased eGC height and stiffness, indicating shedding of the eGC. C5a enhan...
This study demonstrates that dysregulated C5a activation during AMI results in eGC damage with subsequent endothelial dysfunction and reduced NO bioavailability, indicating progressively developing va...