questionsmedicales.fr
États, signes et symptômes pathologiques
Processus pathologiques
Nécrose
Infarctus
Infarctus encéphalique
Infarctus cérébral
Infarctus cérébral : Questions médicales fréquentes
Termes MeSH sélectionnés :
Early Detection of Cancer
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Infarctus cérébral : Questions médicales les plus fréquentes",
"headline": "Infarctus cérébral : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Infarctus cérébral : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-01-08",
"dateModified": "2025-04-02",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Infarctus cérébral"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Infarctus encéphalique",
"url": "https://questionsmedicales.fr/mesh/D020520",
"about": {
"@type": "MedicalCondition",
"name": "Infarctus encéphalique",
"code": {
"@type": "MedicalCode",
"code": "D020520",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C23.550.717.489.250"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "CADASIL",
"alternateName": "CADASIL",
"url": "https://questionsmedicales.fr/mesh/D046589",
"about": {
"@type": "MedicalCondition",
"name": "CADASIL",
"code": {
"@type": "MedicalCode",
"code": "D046589",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C23.550.717.489.250.200.100"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Infarctus du territoire de l'artère cérébrale antérieure",
"alternateName": "Infarction, Anterior Cerebral Artery",
"url": "https://questionsmedicales.fr/mesh/D020243",
"about": {
"@type": "MedicalCondition",
"name": "Infarctus du territoire de l'artère cérébrale antérieure",
"code": {
"@type": "MedicalCode",
"code": "D020243",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C23.550.717.489.250.200.400"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Infarctus du territoire de l'artère cérébrale moyenne",
"alternateName": "Infarction, Middle Cerebral Artery",
"url": "https://questionsmedicales.fr/mesh/D020244",
"about": {
"@type": "MedicalCondition",
"name": "Infarctus du territoire de l'artère cérébrale moyenne",
"code": {
"@type": "MedicalCode",
"code": "D020244",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C23.550.717.489.250.200.450"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Infarctus du territoire de l'artère cérébrale postérieure",
"alternateName": "Infarction, Posterior Cerebral Artery",
"url": "https://questionsmedicales.fr/mesh/D020762",
"about": {
"@type": "MedicalCondition",
"name": "Infarctus du territoire de l'artère cérébrale postérieure",
"code": {
"@type": "MedicalCode",
"code": "D020762",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C23.550.717.489.250.200.475"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Infarctus cérébral",
"alternateName": "Cerebral Infarction",
"code": {
"@type": "MedicalCode",
"code": "D002544",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Alexander E Merkler",
"url": "https://questionsmedicales.fr/author/Alexander%20E%20Merkler",
"affiliation": {
"@type": "Organization",
"name": "Department of Neurology, Weill Cornell Medical College, New York, NY, USA; Clinical and Translational Neuroscience Unit, Weill Cornell Medical College, New York, NY, USA. Electronic address: alm9097@med.cornell.edu."
}
},
{
"@type": "Person",
"name": "Hooman Kamel",
"url": "https://questionsmedicales.fr/author/Hooman%20Kamel",
"affiliation": {
"@type": "Organization",
"name": "Department of Neurology, Weill Cornell Medical College, New York, NY, USA; Clinical and Translational Neuroscience Unit, Weill Cornell Medical College, New York, NY, USA."
}
},
{
"@type": "Person",
"name": "Jonathan W Weinsaft",
"url": "https://questionsmedicales.fr/author/Jonathan%20W%20Weinsaft",
"affiliation": {
"@type": "Organization",
"name": "Department of Medicine, Weill Cornell Medical College, New York, NY, USA."
}
},
{
"@type": "Person",
"name": "Grégoire Boulouis",
"url": "https://questionsmedicales.fr/author/Gr%C3%A9goire%20Boulouis",
"affiliation": {
"@type": "Organization",
"name": "Department of Neuroradiology, Centre Hospitalier Saint-Anne, Paris, France."
}
},
{
"@type": "Person",
"name": "Nan Wang",
"url": "https://questionsmedicales.fr/author/Nan%20Wang",
"affiliation": {
"@type": "Organization",
"name": "Department of Neurology Inspection, People's Hospital of Liaoning Province, Shenyang, Liaoning 110016, P.R. China."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Association between high body mass index and prognosis of patients with early-stage breast cancer: A systematic review and meta-analysis.",
"datePublished": "2023-04-05",
"url": "https://questionsmedicales.fr/article/38327841",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.cpt.2023.03.002"
}
},
{
"@type": "ScholarlyArticle",
"name": "Oncologic and obstetric outcomes of early-stage epithelial ovarian cancer patients who underwent fertility-sparing surgery: A retrospective study.",
"datePublished": "2023-03-23",
"url": "https://questionsmedicales.fr/article/36825554",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/ijgo.14732"
}
},
{
"@type": "ScholarlyArticle",
"name": "Real World and Public Health Perspectives of Intraoperative Radiotherapy in Early-Stage Breast Cancer: A Multidisciplinary Analysis Beyond the Statistical Facts.",
"datePublished": "2023-03-20",
"url": "https://questionsmedicales.fr/article/37025715",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.7759/cureus.36432"
}
},
{
"@type": "ScholarlyArticle",
"name": "The Impact of Race and Age on Response to Neoadjuvant Therapy and Long-Term Outcomes in Black and White Women with Early-Stage Breast Cancer.",
"datePublished": "2023-03-16",
"url": "https://questionsmedicales.fr/article/36993723",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.21203/rs.3.rs-2667554/v1"
}
},
{
"@type": "ScholarlyArticle",
"name": "Comparison of Recurrence Patterns between Adenocarcinoma and Squamous Cell Carcinoma after Stereotactic Body Radiotherapy for Early-Stage Lung Cancer.",
"datePublished": "2023-01-31",
"url": "https://questionsmedicales.fr/article/36765844",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/cancers15030887"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "États, signes et symptômes pathologiques",
"item": "https://questionsmedicales.fr/mesh/D013568"
},
{
"@type": "ListItem",
"position": 3,
"name": "Processus pathologiques",
"item": "https://questionsmedicales.fr/mesh/D010335"
},
{
"@type": "ListItem",
"position": 4,
"name": "Nécrose",
"item": "https://questionsmedicales.fr/mesh/D009336"
},
{
"@type": "ListItem",
"position": 5,
"name": "Infarctus",
"item": "https://questionsmedicales.fr/mesh/D007238"
},
{
"@type": "ListItem",
"position": 6,
"name": "Infarctus encéphalique",
"item": "https://questionsmedicales.fr/mesh/D020520"
},
{
"@type": "ListItem",
"position": 7,
"name": "Infarctus cérébral",
"item": "https://questionsmedicales.fr/mesh/D002544"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Infarctus cérébral - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Infarctus cérébral",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-03",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Infarctus cérébral",
"description": "Comment diagnostique-t-on un infarctus cérébral ?\nQuels tests sont effectués après un AVC suspecté ?\nQuels signes indiquent un infarctus cérébral ?\nQuelle est l'importance du temps dans le diagnostic ?\nPeut-on utiliser l'électroencéphalogramme ?",
"url": "https://questionsmedicales.fr/mesh/D002544?mesh_terms=Early+Detection+of+Cancer&page=1000#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Infarctus cérébral",
"description": "Quels sont les symptômes courants d'un infarctus cérébral ?\nComment reconnaître un AVC ?\nLes symptômes peuvent-ils varier ?\nUn AVC peut-il provoquer des pertes de mémoire ?\nLes symptômes sont-ils toujours soudains ?",
"url": "https://questionsmedicales.fr/mesh/D002544?mesh_terms=Early+Detection+of+Cancer&page=1000#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Infarctus cérébral",
"description": "Comment prévenir un infarctus cérébral ?\nLe tabagisme augmente-t-il le risque ?\nLe diabète influence-t-il le risque d'AVC ?\nLes antécédents familiaux jouent-ils un rôle ?\nL'exercice régulier est-il bénéfique ?",
"url": "https://questionsmedicales.fr/mesh/D002544?mesh_terms=Early+Detection+of+Cancer&page=1000#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Infarctus cérébral",
"description": "Quels traitements sont disponibles pour un infarctus cérébral ?\nQuand utiliser des thrombolytiques ?\nLa chirurgie est-elle nécessaire ?\nQuel rôle joue la réhabilitation ?\nLes traitements varient-ils selon le type d'AVC ?",
"url": "https://questionsmedicales.fr/mesh/D002544?mesh_terms=Early+Detection+of+Cancer&page=1000#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Infarctus cérébral",
"description": "Quelles sont les complications possibles d'un infarctus cérébral ?\nUn infarctus cérébral peut-il entraîner des infections ?\nLes complications sont-elles réversibles ?\nComment les complications affectent-elles la réhabilitation ?\nLes complications psychologiques sont-elles fréquentes ?",
"url": "https://questionsmedicales.fr/mesh/D002544?mesh_terms=Early+Detection+of+Cancer&page=1000#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Infarctus cérébral",
"description": "Quels sont les principaux facteurs de risque d'infarctus cérébral ?\nL'âge influence-t-il le risque d'AVC ?\nLe stress peut-il être un facteur de risque ?\nLes maladies cardiaques augmentent-elles le risque ?\nLe cholestérol élevé est-il un facteur de risque ?",
"url": "https://questionsmedicales.fr/mesh/D002544?mesh_terms=Early+Detection+of+Cancer&page=1000#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostique-t-on un infarctus cérébral ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un scanner ou une IRM cérébrale est utilisé pour visualiser les lésions."
}
},
{
"@type": "Question",
"name": "Quels tests sont effectués après un AVC suspecté ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins et des examens neurologiques sont réalisés pour évaluer l'état."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent un infarctus cérébral ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme une faiblesse soudaine, des troubles de la parole ou de la vision."
}
},
{
"@type": "Question",
"name": "Quelle est l'importance du temps dans le diagnostic ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un diagnostic rapide est crucial pour limiter les dommages cérébraux."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser l'électroencéphalogramme ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'EEG n'est pas standard pour l'infarctus, mais peut aider à évaluer l'activité cérébrale."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes courants d'un infarctus cérébral ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Faiblesse d'un côté du corps, troubles de la parole, et maux de tête soudains."
}
},
{
"@type": "Question",
"name": "Comment reconnaître un AVC ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utilisez l'acronyme FAST : Faiblesse, Affaissement, Speech (parole), Temps."
}
},
{
"@type": "Question",
"name": "Les symptômes peuvent-ils varier ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes dépendent de la zone du cerveau touchée et de la gravité."
}
},
{
"@type": "Question",
"name": "Un AVC peut-il provoquer des pertes de mémoire ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles cognitifs, y compris des pertes de mémoire, peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les symptômes sont-ils toujours soudains ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Pas toujours, certains infarctus peuvent se manifester par des symptômes progressifs."
}
},
{
"@type": "Question",
"name": "Comment prévenir un infarctus cérébral ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une alimentation saine, faire de l'exercice et contrôler la pression artérielle."
}
},
{
"@type": "Question",
"name": "Le tabagisme augmente-t-il le risque ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme est un facteur de risque majeur pour les AVC."
}
},
{
"@type": "Question",
"name": "Le diabète influence-t-il le risque d'AVC ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète mal contrôlé augmente le risque d'infarctus cérébral."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux d'AVC augmentent le risque personnel."
}
},
{
"@type": "Question",
"name": "L'exercice régulier est-il bénéfique ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier aide à réduire le risque d'infarctus cérébral."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour un infarctus cérébral ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des médicaments anticoagulants et la réhabilitation."
}
},
{
"@type": "Question",
"name": "Quand utiliser des thrombolytiques ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils sont administrés dans les premières heures après l'apparition des symptômes."
}
},
{
"@type": "Question",
"name": "La chirurgie est-elle nécessaire ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Dans certains cas, une intervention chirurgicale peut être nécessaire pour retirer un caillot."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la réhabilitation ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La réhabilitation aide à récupérer les fonctions perdues et à améliorer la qualité de vie."
}
},
{
"@type": "Question",
"name": "Les traitements varient-ils selon le type d'AVC ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements diffèrent entre les AVC ischémiques et hémorragiques."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles d'un infarctus cérébral ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles de la parole, des paralysies et des problèmes cognitifs."
}
},
{
"@type": "Question",
"name": "Un infarctus cérébral peut-il entraîner des infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des infections comme la pneumonie peuvent survenir après un AVC."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être réversibles avec un traitement approprié."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles la réhabilitation ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent ralentir le processus de réhabilitation et nécessiter des soins supplémentaires."
}
},
{
"@type": "Question",
"name": "Les complications psychologiques sont-elles fréquentes ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles comme la dépression peuvent survenir après un infarctus cérébral."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque d'infarctus cérébral ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'hypertension, le diabète, le tabagisme et l'obésité."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque d'AVC ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque d'infarctus cérébral augmente avec l'âge."
}
},
{
"@type": "Question",
"name": "Le stress peut-il être un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut contribuer à l'augmentation du risque d'AVC."
}
},
{
"@type": "Question",
"name": "Les maladies cardiaques augmentent-elles le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les maladies cardiaques sont un facteur de risque important pour les AVC."
}
},
{
"@type": "Question",
"name": "Le cholestérol élevé est-il un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un taux de cholestérol élevé peut augmenter le risque d'infarctus cérébral."
}
}
]
}
]
}
A high body mass index (BMI) can indicate overweight or obesity and is a crucial risk factor for breast cancer survivors. However, the association between high BMI and prognosis in early-stage breast ...
The PubMed, Embase, and Cochrane Library databases and proceedings of major oncological conferences related to the effects of BMI on the prognosis of breast cancer were searched up to November 2021. F...
Twenty retrospective cohort studies with 33,836 patients with EBC were included. Overweight patients had worse DFS (HR: 1.16, 95% CI: 1.05-1.27,...
Compared with normal weight, increased body weight (overweight, obesity, and high BMI) led to worse DFS and OS in patients with EBC. Once validated, these results should be considered in the developme...
This study aimed to assess the long-term oncologic and obstetric outcomes of women with epithelial ovarian cancer who underwent fertility-sparing surgery....
A total of 68 patients observed between March 2007 and July 2021 were included in this retrospective study. Unilateral salpingo-oophorectomy and uterine preservation with staging surgery were the main...
The median age of the patients was 30.5 years. The median follow-up time was 60.5 months. Disease recurrence occurred in 15 (22.1%) of the patients. Five-year disease-free survival and overall surviva...
Fertility preservation is safe for invasive epithelial ovarian cancer at early stages for women in the reproductive era. Disease recurrence and OS results are similar to standard treatment at early st...
Breast conservation therapy (BCT) (usually a lumpectomy plus radiotherapy (RT)) has become a standard alternative to radical mastectomy in early-stage breast cancers with equal, if not higher, surviva...
There are a paucity of data and a pressing need to evaluate response to neoadjuvant chemotherapy (NACT) and determine long-term outcomes in young Black women with early-stage breast cancer (EBC)....
We analyzed data from 2,196 Black and White women with EBC treated at the University of Chicago over the last 2 decades. Patients were divided into groups based on race and age at diagnosis: Black wom...
Young Black women had the highest risk of recurrence, which was 22% higher than young White women (p=0.434) and 76% higher than older Black women (p=0.008). These age/racial differences in recurrence ...
Black women with EBC had significantly worse outcomes compared to White women in our cohort study. There is an urgent need to understand the disparities in outcomes between Black and White breast canc...
We compared recurrence patterns between adenocarcinoma (ADC) and squamous cell carcinoma (SCC) after stereotactic body radiotherapy (SBRT) for early-stage lung cancer. Patients with ADC and SCC histol...
In this study, fluoromisonidazole positron emission tomography (F-MISO PET/CT) was used to evaluate tumor hypoxia and re-oxygenation in patients with lung tumors treated with stereotactic body radiati...
Patients with T1-2 N0 lung cancer were included in this study. The prescribed dose was 48-52 Gy in four fractions. F-MISO PET/CT was performed twice, before SBRT and 1-3 days after the first irradiati...
Between 2016 and 2021, 15 patients were included. Pre-treatment tumor hypoxia was observed in nine tumors (60 %). TMR in all six tumors without pre-treatment hypoxia rose after single high-dose irradi...
Tumor hypoxia reduced after single high-dose irradiation. Tumor with F-MISO uptake seems to be an unfavorable prognostic factor in lung SBRT....
Immune checkpoint inhibitor (ICI) therapy has proven to be a promising treatment for colorectal cancer (CRC). We aim to investigate the relationship between DNA methylation and tumor mutation burden (...
A total of 536 CRC tissues from the Cancer Genome Atlas (TCGA) with mutation data were collected and subjected to calculate TMB. 80 CRC patients with high TMB and paired normal tissues were selected a...
A positive correlation between differential methylation positions and TMB level was observed in TCGA CRC cohort (r=0.45). The diagnostic score that consisted of methylation levels of four genes (...
By integrating analyses of methylation and mutation data, it is suggested that DNA methylation patterns combined with TMB serve as a novel potential biomarker for early screening in more high-TMB popu...
The goal of this project was to utilize mechanistic simulation to demonstrate a methodology that could determine drug combination dose schedules and dose intensities that would be most effective in el...
The most appropriate criteria and timing for palliative care referral remain a critical issue, especially in patients with metastatic breast cancer for whom long-term chemosensibility and survival are...
This randomized prospective study enrolled adult women with metastatic breast cancer and visceral metastases with a 3rd- or 4th-line chemotherapy (CT). Patients received usual oncology care with a pal...
From January 2009 to November 2012, two authorized cancer centers included 98 women (EPC: 50; S: 48). Thirty-seven (77.1%, 95%CI 62.7-88%) patients in the EPC group had a subsequent chemotherapy presc...
EPC in metastatic breast cancer patients did not impact the prescription rate of additional chemotherapy in patients a 3rd- or 4th-line chemotherapy for metastatic breast cancer; however, EPC may cont...
ClinicalTrial.gov identifier: NCT00905281, May 20, 2009....
Calcitonin (Ctn) is widely used as a marker in the diagnosis, prognosis, and postoperative follow-up of patients with medullary thyroid carcinoma (MTC). The prognostic value of postoperative calcitoni...
We retrospectively reviewed patients with MTC in Sun Yat-sen University Cancer Center (SYSUCC) between 2000 and 2022. CR is defined as the ratio of postoperative Ctn level on the day of discharge divi...
In total, 112 sporadic MTC patients were included in this study. The optimal cut-off value of CR that predicted disease recurrence was 0.125. Patients with CR≥0.125 showed significantly worse RFS than...
We demonstrate that CR is a strong prognostic marker to predict structural recurrence in patients with sporadic MTC. The nomogram incorporating CR provided useful prediction of RFS for patients with s...