Titre : Dentinogenèse imparfaite

Dentinogenèse imparfaite : Questions médicales fréquentes

Termes MeSH sélectionnés :

Early Detection of Cancer
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Dentinogenèse imparfaite : Questions médicales les plus fréquentes", "headline": "Dentinogenèse imparfaite : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Dentinogenèse imparfaite : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-02", "dateModified": "2025-03-29", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Dentinogenèse imparfaite" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Malformations dentaires", "url": "https://questionsmedicales.fr/mesh/D014071", "about": { "@type": "MedicalCondition", "name": "Malformations dentaires", "code": { "@type": "MedicalCode", "code": "D014071", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "C16.131.850.800" } } }, "about": { "@type": "MedicalCondition", "name": "Dentinogenèse imparfaite", "alternateName": "Dentinogenesis Imperfecta", "code": { "@type": "MedicalCode", "code": "D003811", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Zhi Chen", "url": "https://questionsmedicales.fr/author/Zhi%20Chen", "affiliation": { "@type": "Organization", "name": "The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory for Oral Biomedicine of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China." } }, { "@type": "Person", "name": "Jung-Wook Kim", "url": "https://questionsmedicales.fr/author/Jung-Wook%20Kim", "affiliation": { "@type": "Organization", "name": "Department of Molecular Genetics, School of Dentistry & Dental Research Institute, Seoul National University, Seoul, Korea." } }, { "@type": "Person", "name": "Ning Li", "url": "https://questionsmedicales.fr/author/Ning%20Li", "affiliation": { "@type": "Organization", "name": "Institute of Stomatology, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, PR China; Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, PR China." } }, { "@type": "Person", "name": "Jianfeng Ma", "url": "https://questionsmedicales.fr/author/Jianfeng%20Ma", "affiliation": { "@type": "Organization", "name": "Institute of Stomatology, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, PR China; Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, PR China. Electronic address: dentisitmacn@aliyun.com." } }, { "@type": "Person", "name": "Shengbin Huang", "url": "https://questionsmedicales.fr/author/Shengbin%20Huang", "affiliation": { "@type": "Organization", "name": "Institute of Stomatology, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, PR China; Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, PR China. Electronic address: huangsb003@wmu.edu.cn." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "DNA Methylation in the Fields of Prenatal Diagnosis and Early Detection of Cancers.", "datePublished": "2023-07-20", "url": "https://questionsmedicales.fr/article/37511475", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3390/ijms241411715" } }, { "@type": "ScholarlyArticle", "name": "A Liquid Biopsy Signature for the Early Detection of Gastric Cancer in Patients.", "datePublished": "2023-03-07", "url": "https://questionsmedicales.fr/article/36894035", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1053/j.gastro.2023.02.044" } }, { "@type": "ScholarlyArticle", "name": "Early detection of cancer therapy cardiotoxicity by radionuclide angiography: An update.", "datePublished": "2023-02-28", "url": "https://questionsmedicales.fr/article/36855007", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s12350-023-03202-w" } }, { "@type": "ScholarlyArticle", "name": "Optimal age to stop prostate cancer screening and early detection.", "datePublished": "2023-08-19", "url": "https://questionsmedicales.fr/article/37598870", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.jcpo.2023.100443" } }, { "@type": "ScholarlyArticle", "name": "Serum IgG N-glycans enable early detection and early relapse prediction of colorectal cancer.", "datePublished": "2022-10-03", "url": "https://questionsmedicales.fr/article/36121650", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/ijc.34298" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Malformations et maladies congénitales, héréditaires et néonatales", "item": "https://questionsmedicales.fr/mesh/D009358" }, { "@type": "ListItem", "position": 3, "name": "Malformations", "item": "https://questionsmedicales.fr/mesh/D000013" }, { "@type": "ListItem", "position": 4, "name": "Malformations du système stomatognathique", "item": "https://questionsmedicales.fr/mesh/D018640" }, { "@type": "ListItem", "position": 5, "name": "Malformations dentaires", "item": "https://questionsmedicales.fr/mesh/D014071" }, { "@type": "ListItem", "position": 6, "name": "Dentinogenèse imparfaite", "item": "https://questionsmedicales.fr/mesh/D003811" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Dentinogenèse imparfaite - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Dentinogenèse imparfaite", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-10", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Dentinogenèse imparfaite", "description": "Comment diagnostique-t-on la dentinogenèse imparfaite ?\nQuels tests génétiques sont utilisés ?\nLes antécédents familiaux sont-ils importants ?\nQuels signes radiographiques sont typiques ?\nPeut-on confondre cette maladie avec d'autres ?", "url": "https://questionsmedicales.fr/mesh/D003811?mesh_terms=Early+Detection+of+Cancer&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Dentinogenèse imparfaite", "description": "Quels sont les symptômes principaux ?\nLes dents peuvent-elles se casser facilement ?\nY a-t-il des douleurs associées ?\nLes dents changent-elles de couleur ?\nY a-t-il des problèmes d'occlusion ?", "url": "https://questionsmedicales.fr/mesh/D003811?mesh_terms=Early+Detection+of+Cancer&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Dentinogenèse imparfaite", "description": "Comment prévenir la dentinogenèse imparfaite ?\nLes soins dentaires réguliers sont-ils importants ?\nL'alimentation joue-t-elle un rôle ?\nLes fluorures sont-ils bénéfiques ?\nFaut-il éviter certains aliments ?", "url": "https://questionsmedicales.fr/mesh/D003811?mesh_terms=Early+Detection+of+Cancer&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Dentinogenèse imparfaite", "description": "Quels traitements sont disponibles ?\nLes traitements orthodontiques sont-ils efficaces ?\nDes traitements esthétiques sont-ils possibles ?\nComment prévenir les caries ?\nLes implants dentaires sont-ils une option ?", "url": "https://questionsmedicales.fr/mesh/D003811?mesh_terms=Early+Detection+of+Cancer&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Dentinogenèse imparfaite", "description": "Quelles complications peuvent survenir ?\nLes infections dentaires sont-elles fréquentes ?\nY a-t-il un risque accru de perte dentaire ?\nLes problèmes d'élocution sont-ils possibles ?\nLes complications psychologiques sont-elles courantes ?", "url": "https://questionsmedicales.fr/mesh/D003811?mesh_terms=Early+Detection+of+Cancer&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Dentinogenèse imparfaite", "description": "Quels sont les facteurs de risque génétiques ?\nL'âge influence-t-il la gravité des symptômes ?\nLes habitudes de vie affectent-elles la maladie ?\nY a-t-il un lien avec d'autres maladies ?\nLes facteurs environnementaux jouent-ils un rôle ?", "url": "https://questionsmedicales.fr/mesh/D003811?mesh_terms=Early+Detection+of+Cancer&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostique-t-on la dentinogenèse imparfaite ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur l'examen clinique et des radiographies dentaires." } }, { "@type": "Question", "name": "Quels tests génétiques sont utilisés ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques peuvent identifier des mutations dans les gènes COL1A1 et COL1A2." } }, { "@type": "Question", "name": "Les antécédents familiaux sont-ils importants ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les antécédents familiaux aident à établir un diagnostic de dentinogenèse imparfaite." } }, { "@type": "Question", "name": "Quels signes radiographiques sont typiques ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les dents présentent une opacité réduite et une forme anormale sur les radiographies." } }, { "@type": "Question", "name": "Peut-on confondre cette maladie avec d'autres ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut être confondue avec d'autres troubles dentaires comme l'émail hypoplasique." } }, { "@type": "Question", "name": "Quels sont les symptômes principaux ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des dents décolorées, fragiles et une sensibilité accrue." } }, { "@type": "Question", "name": "Les dents peuvent-elles se casser facilement ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les dents sont très fragiles et peuvent se casser facilement sous pression." } }, { "@type": "Question", "name": "Y a-t-il des douleurs associées ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Des douleurs peuvent survenir en raison de la sensibilité accrue des dents." } }, { "@type": "Question", "name": "Les dents changent-elles de couleur ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles peuvent apparaître bleues, brunes ou jaunes en raison de la dentine anormale." } }, { "@type": "Question", "name": "Y a-t-il des problèmes d'occlusion ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des problèmes d'occlusion peuvent survenir en raison de la forme anormale des dents." } }, { "@type": "Question", "name": "Comment prévenir la dentinogenèse imparfaite ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de prévention, mais un diagnostic précoce aide à gérer les symptômes." } }, { "@type": "Question", "name": "Les soins dentaires réguliers sont-ils importants ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des soins dentaires réguliers aident à prévenir les complications et à maintenir la santé dentaire." } }, { "@type": "Question", "name": "L'alimentation joue-t-elle un rôle ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation riche en calcium et en vitamine D peut soutenir la santé dentaire." } }, { "@type": "Question", "name": "Les fluorures sont-ils bénéfiques ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "L'utilisation de fluorures peut aider à renforcer l'émail et prévenir les caries." } }, { "@type": "Question", "name": "Faut-il éviter certains aliments ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les aliments durs et collants peut réduire le risque de fractures dentaires." } }, { "@type": "Question", "name": "Quels traitements sont disponibles ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des restaurations dentaires, des couronnes et des soins préventifs." } }, { "@type": "Question", "name": "Les traitements orthodontiques sont-ils efficaces ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les traitements orthodontiques peuvent aider à corriger l'alignement des dents." } }, { "@type": "Question", "name": "Des traitements esthétiques sont-ils possibles ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des traitements esthétiques comme le blanchiment peuvent être envisagés." } }, { "@type": "Question", "name": "Comment prévenir les caries ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Une bonne hygiène bucco-dentaire et des visites régulières chez le dentiste sont essentielles." } }, { "@type": "Question", "name": "Les implants dentaires sont-ils une option ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Les implants peuvent être envisagés, mais leur succès dépend de la santé osseuse." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des fractures dentaires, des infections et des problèmes d'occlusion." } }, { "@type": "Question", "name": "Les infections dentaires sont-elles fréquentes ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les infections peuvent survenir en raison de la fragilité des dents et des caries." } }, { "@type": "Question", "name": "Y a-t-il un risque accru de perte dentaire ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la fragilité des dents augmente le risque de perte dentaire précoce." } }, { "@type": "Question", "name": "Les problèmes d'élocution sont-ils possibles ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des problèmes d'élocution peuvent survenir en raison de l'alignement dentaire anormal." } }, { "@type": "Question", "name": "Les complications psychologiques sont-elles courantes ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les problèmes esthétiques peuvent entraîner des complications psychologiques comme l'anxiété." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque génétiques ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les antécédents familiaux de dentinogenèse imparfaite augmentent le risque de la maladie." } }, { "@type": "Question", "name": "L'âge influence-t-il la gravité des symptômes ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes peuvent s'aggraver avec l'âge en raison de l'usure dentaire." } }, { "@type": "Question", "name": "Les habitudes de vie affectent-elles la maladie ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes comme le tabagisme peuvent aggraver les problèmes dentaires." } }, { "@type": "Question", "name": "Y a-t-il un lien avec d'autres maladies ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la dentinogenèse imparfaite peut être associée à d'autres troubles génétiques comme l'ostéogenèse imparfaite." } }, { "@type": "Question", "name": "Les facteurs environnementaux jouent-ils un rôle ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs environnementaux comme l'exposition à des toxines peuvent influencer la maladie." } } ] } ] }

Sources (10000 au total)

A Liquid Biopsy Signature for the Early Detection of Gastric Cancer in Patients.

Diagnosing gastric cancer (GC) while the disease remains eligible for surgical resection is challenging. In view of this clinical challenge, novel and robust biomarkers for early detection thus improv... The present 3-step study incorporated data from 2141 patients, including 888 with GC, 158 with chronic atrophic gastritis, 193 with intestinal metaplasia, 501 healthy donors, and 401 with other gastro... In discovery phase, one LR (GClnc1) was found to be up-regulated in both tissue and circulating EV samples with an area under the curve (AUC) of 0.9369 (95% confidence interval [CI], 0.9073-0.9664) fo... EV-derived GClnc1 serves as a circulating biomarker for the early detection of GC, thus providing opportunities for curative surgery and improved survival outcomes....

Optimal age to stop prostate cancer screening and early detection.

Prostate Cancer screening should be discontinued at older ages because competing mortality risks eventually dominate the risk of Prostate Cancer and harms exceed benefits. We explored the Prostate Can... We applied Bellman Equations to formulate the net benefits biopsy and "do nothing". Using difference between the net benefits of two alternatives, we calculated the stopping age. The cancer states wer... Our results suggested that Prostate Cancer screening stopping ages from the patient, healthcare system, and social were 70, 68, and 68 respectively. The univariate sensitivity analysis showed that the... Men should not be screened for Prostate Cancer beyond 70 years old, as this results in the net benefit of "do nothing" above the biopsy. Nevertheless, this finding needs to be further studied with mor...

Ovarian Cancer-Self Assessment: An Innovation for Early Detection and Risk Assessment of Ovarian Cancer.

The modality to detect ovarian cancer at an early stage is very limited. Early diagnosis determines the prognosis. This study aimed to develop a risk assessment tool for early detection of ovarian can... This study was carried out as a cohort study of patients diagnosed with suspected ovarian tumors undergoing cytoreduction operation at Hasan Sadikin Hospital, Bandung, from December 2019 to September ... In total, 115 patients included in this study. The differences were statistically significant in terms of the six variables (abdominal bloating, nausea/vomiting, decreased of appetite, fullness, menst... Risk assessments based on ovarian cancer self-assessment unfortunately were not comparable to postoperative histopathology as a single predictor. Ten variables in ovarian cancer artificial intelligenc...

Integration of multiomics features for blood-based early detection of colorectal cancer.

Early detection of colorectal cancer (CRC) significantly enhances patient outcomes. Conventional CRC screening tools, like endoscopy and stool-based tests, have constraints due to their invasiveness o... In this research, we harnessed the Mutation Capsule Plus (MCP) technology to profile an array of genomic characteristics from cfDNA procured from a single blood draw. This profiling encompassed DNA me... This model was subsequently validated in another cohort comprising 89 CRC patients and 95 healthy controls. Remarkably, the model achieved an area under the curve (AUC) of 0.981 (95% confidence interv... Our findings underscore the clinical potential of our multiomics liquid biopsy test, indicating its prospective role as a noninvasive method for early-stage CRC detection. This multiomics approach hol...

Prospective cohort for early detection of liver cancer (Pearl): a study protocol.

Hepatocellular carcinoma (HCC) is the fastest-rising and fourth most common cause of cancer death worldwide. Liver cirrhosis is the largest underlying risk factor for HCC. Therefore, patients with cir... This is a UK-based prospective, longitudinal, diagnostic, prognostic, multicentre, non-CTIMP study. Aiming to recruit 3000 patients with liver cirrhosis without a HCC diagnosis, the Pearl cohort will ... Ethical approval has been granted by REC and the trial is registered on ClinicalTrials.gov. The results will be published in peer-reviewed journals and presented at relevant meetings.... NCT05541601....