questionsmedicales.fr
Techniques d'investigation
Conservation biologique
Cryoconservation
Lyophilisation
Lyophilisation : Questions médicales fréquentes
Termes MeSH sélectionnés :
Single-Cell Gene Expression Analysis
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Lyophilisation : Questions médicales les plus fréquentes",
"headline": "Lyophilisation : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Lyophilisation : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-01-28",
"dateModified": "2025-04-22",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Lyophilisation"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Cryoconservation",
"url": "https://questionsmedicales.fr/mesh/D015925",
"about": {
"@type": "MedicalCondition",
"name": "Cryoconservation",
"code": {
"@type": "MedicalCode",
"code": "D015925",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "E05.760.156"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Congélation-dissolution",
"alternateName": "Freeze Substitution",
"url": "https://questionsmedicales.fr/mesh/D017110",
"about": {
"@type": "MedicalCondition",
"name": "Congélation-dissolution",
"code": {
"@type": "MedicalCode",
"code": "D017110",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "E05.760.156.260.270"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Lyophilisation",
"alternateName": "Freeze Drying",
"code": {
"@type": "MedicalCode",
"code": "D005612",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Davide Fissore",
"url": "https://questionsmedicales.fr/author/Davide%20Fissore",
"affiliation": {
"@type": "Organization",
"name": "Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy. Electronic address: davide.fissore@polito.it."
}
},
{
"@type": "Person",
"name": "Nuria Martínez-Navarrete",
"url": "https://questionsmedicales.fr/author/Nuria%20Mart%C3%ADnez-Navarrete",
"affiliation": {
"@type": "Organization",
"name": "Food Technology Department, Food Investigation and Innovation Group, Universitat Politècnica de València, Valencia, Spain."
}
},
{
"@type": "Person",
"name": "Roberto Pisano",
"url": "https://questionsmedicales.fr/author/Roberto%20Pisano",
"affiliation": {
"@type": "Organization",
"name": "Department of Applied Science and Technology, Politecnico di Torino, 24 corso Duca degli Abruzzi, Torino 10129, Italy."
}
},
{
"@type": "Person",
"name": "Linlin Li",
"url": "https://questionsmedicales.fr/author/Linlin%20Li",
"affiliation": {
"@type": "Organization",
"name": "College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China."
}
},
{
"@type": "Person",
"name": "Weiwei Cao",
"url": "https://questionsmedicales.fr/author/Weiwei%20Cao",
"affiliation": {
"@type": "Organization",
"name": "College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Single-cell RNA-seq analysis identifies distinct myeloid cells in a case with encephalitis temporally associated with COVID-19 vaccination.",
"datePublished": "2023-02-23",
"url": "https://questionsmedicales.fr/article/36911677",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3389/fimmu.2023.998233"
}
},
{
"@type": "ScholarlyArticle",
"name": "Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell RNA-seq data.",
"datePublished": "2023-01-21",
"url": "https://questionsmedicales.fr/article/36681709",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1038/s41598-022-26434-1"
}
},
{
"@type": "ScholarlyArticle",
"name": "CD8 + T-cell marker genes reveal different immune subtypes of oral lichen planus by integrating single-cell RNA-seq and bulk RNA-sequencing.",
"datePublished": "2023-07-08",
"url": "https://questionsmedicales.fr/article/37422617",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s12903-023-03138-0"
}
},
{
"@type": "ScholarlyArticle",
"name": "Comprehensive analysis of single-cell RNA-seq and bulk RNA-seq revealed the heterogeneity and convergence of the immune microenvironment in renal cell carcinoma.",
"datePublished": "2023-06-02",
"url": "https://questionsmedicales.fr/article/37264263",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s10142-023-01113-0"
}
},
{
"@type": "ScholarlyArticle",
"name": "Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes.",
"datePublished": "2023-04-18",
"url": "https://questionsmedicales.fr/article/37190091",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/cells12081182"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Techniques d'investigation",
"item": "https://questionsmedicales.fr/mesh/D008919"
},
{
"@type": "ListItem",
"position": 3,
"name": "Conservation biologique",
"item": "https://questionsmedicales.fr/mesh/D011309"
},
{
"@type": "ListItem",
"position": 4,
"name": "Cryoconservation",
"item": "https://questionsmedicales.fr/mesh/D015925"
},
{
"@type": "ListItem",
"position": 5,
"name": "Lyophilisation",
"item": "https://questionsmedicales.fr/mesh/D005612"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Lyophilisation - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Lyophilisation",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-15",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Lyophilisation",
"description": "Comment savoir si un produit est lyophilisé ?\nQuels tests pour vérifier la qualité d'un produit lyophilisé ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Single-Cell+Gene+Expression+Analysis&page=5#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Lyophilisation",
"description": "Quels sont les signes d'un produit mal lyophilisé ?\nY a-t-il des effets secondaires de la lyophilisation ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Single-Cell+Gene+Expression+Analysis&page=5#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Lyophilisation",
"description": "Comment éviter la dégradation des produits lyophilisés ?\nQuelles conditions sont idéales pour stocker des produits lyophilisés ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Single-Cell+Gene+Expression+Analysis&page=5#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Lyophilisation",
"description": "Comment réhydrater un produit lyophilisé ?\nQuels produits sont souvent lyophilisés ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Single-Cell+Gene+Expression+Analysis&page=5#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Lyophilisation",
"description": "Quels risques si un produit lyophilisé est mal stocké ?\nPeut-on consommer un produit lyophilisé périmé ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Single-Cell+Gene+Expression+Analysis&page=5#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Lyophilisation",
"description": "Quels facteurs influencent la qualité de la lyophilisation ?\nQuels produits sont plus sensibles à la lyophilisation ?",
"url": "https://questionsmedicales.fr/mesh/D005612?mesh_terms=Single-Cell+Gene+Expression+Analysis&page=5#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment savoir si un produit est lyophilisé ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un produit lyophilisé est léger, friable et conserve sa forme d'origine après réhydratation."
}
},
{
"@type": "Question",
"name": "Quels tests pour vérifier la qualité d'un produit lyophilisé ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de solubilité, d'humidité résiduelle et d'analyse organoleptique sont effectués."
}
},
{
"@type": "Question",
"name": "Quels sont les signes d'un produit mal lyophilisé ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un produit mal lyophilisé peut présenter des grumeaux, une couleur anormale ou une odeur désagréable."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires de la lyophilisation ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "La lyophilisation n'a pas d'effets secondaires directs, mais peut altérer certains nutriments."
}
},
{
"@type": "Question",
"name": "Comment éviter la dégradation des produits lyophilisés ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Conservez-les dans un endroit frais, sec et à l'abri de la lumière pour préserver leur qualité."
}
},
{
"@type": "Question",
"name": "Quelles conditions sont idéales pour stocker des produits lyophilisés ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un environnement à faible humidité et température stable est idéal pour le stockage."
}
},
{
"@type": "Question",
"name": "Comment réhydrater un produit lyophilisé ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il suffit d'ajouter de l'eau à température ambiante ou chaude selon le produit."
}
},
{
"@type": "Question",
"name": "Quels produits sont souvent lyophilisés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les fruits, légumes, viandes et médicaments sont couramment lyophilisés pour la conservation."
}
},
{
"@type": "Question",
"name": "Quels risques si un produit lyophilisé est mal stocké ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mauvais stockage peut entraîner une perte de qualité, de goût et de valeur nutritionnelle."
}
},
{
"@type": "Question",
"name": "Peut-on consommer un produit lyophilisé périmé ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est déconseillé de consommer un produit périmé, même s'il semble intact."
}
},
{
"@type": "Question",
"name": "Quels facteurs influencent la qualité de la lyophilisation ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La température, la pression et la durée du processus de lyophilisation influencent la qualité."
}
},
{
"@type": "Question",
"name": "Quels produits sont plus sensibles à la lyophilisation ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les produits riches en graisses ou en sucres peuvent être plus sensibles à la dégradation."
}
}
]
}
]
}
Recently accumulating evidence has highlighted the rare occurrence of COVID-19 vaccination-induced inflammation in the central nervous system. However, the precise information on immune dysregulation ...
Effective dimension reduction is essential for single cell RNA-seq (scRNAseq) analysis. Principal component analysis (PCA) is widely used, but requires continuous, normally-distributed data; therefore...
Oral lichen planus (OLP) is a local autoimmune disease induced by T-cell dysfunction that frequently affects middle-aged or elderly people, with a higher prevalence in women. CD8 + T cells, also known...
In this study, we preprocessed and downscaled the OLP single-cell dataset GSE211630 cohort downloaded from Gene Expression Omnibus (GEO) to finally obtain the marker genes of CD8 + T cells. Based on t...
After obtaining the intersecting genes of CD8 + T cells related to pathogenesis, OLP patients can be precisely classified into two different subtypes based on unsupervised clustering analysis, and sub...
Classification of OLP into different subtypes improve our current understanding of the underlying pathogenesis of OLP and provides new insights for future studies....
Substantial progress has been made in cancer biology and treatment in recent years, but the clinical outcome of patients with renal cell carcinoma (RCC) remains unsatisfactory. The tumor microenvironm...
Breast cancer (BC) is a heterogeneous disease, which is primarily classified according to hormone receptors and HER2 expression. Despite the many advances in BC diagnosis and management, the identific...
Single-cell RNA-seq data contains a lot of dropouts hampering downstream analyses due to the low number and inefficient capture of mRNAs in individual cells. Here, we present Epi-Impute, a computation...
Neural circuits are mapped in high throughput with single-cell genomics....
Type 2 diabetes (T2D) is a common chronic heterogeneous metabolic disorder. However, the roles of pyroptosis and infiltrating immune cells in islet dysfunction of patients with T2D have yet to be expl...
To achieve this, we performed a conjoint analysis of three bulk RNA-seq datasets of islets to identify T2D-related differentially expressed genes (DEGs). After grouping the islet samples according to ...
We identified 17 pyroptosis-related hub genes. We determined the abundance of 13 immune cell types in the merged matrix and found that these cell types were correlated with the 17 pyroptosis-related h...
This study elucidates the gene signatures associated with pyroptosis and immune infiltration in T2D and provides a critical resource for understanding of islet dysfunction and T2D pathogenesis....
As the most malignant tumor of the female reproductive system, ovarian cancer (OC) has garnered increasing attention. The Warburg effect, driven by glycolysis, accounts for tumor cell proliferation un...
We integrated single-cell data with OC to score glycolysis level in tumor cell subclusters. This led to the identification of a subcluster predominantly characterized by glycolysis, with a strong corr...
Analysis showed that the Malignant 7 subcluster was primarily related to glycolysis. Two OC molecular subtypes, CS1 and CS2, were identified with distinct clinical, biological, and microenvironmental ...
We developed two novel OC subtypes based on glycolysis score, established a stable prognostic model, and identified IGF2 as the marker gene. These insights provided a new avenue for exploring OC's mol...
Male breast cancer (MBC) is a rare but aggressive malignancy with cellular and immunological characteristics that remain unclear. Here, we perform transcriptomic analysis for 111,038 single cells from...