Titre : Gangliosides

Gangliosides : Questions médicales fréquentes

Termes MeSH sélectionnés :

Delphi Technique
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Gangliosides", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-05", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Gangliosides", "description": "Comment diagnostiquer une maladie liée aux gangliosides ?\nQuels tests sont utilisés pour détecter les gangliosides ?\nLes symptômes peuvent-ils indiquer un problème de gangliosides ?\nQuelle imagerie est utile pour évaluer les gangliosides ?\nLes antécédents familiaux sont-ils importants pour le diagnostic ?", "url": "https://questionsmedicales.fr/mesh/D005732?mesh_terms=Delphi+Technique&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Gangliosides", "description": "Quels sont les symptômes courants des gangliosidoses ?\nLes gangliosides affectent-ils le système nerveux ?\nPeut-on observer des symptômes cutanés ?\nLes troubles cognitifs sont-ils liés aux gangliosides ?\nLes douleurs musculaires sont-elles un symptôme ?", "url": "https://questionsmedicales.fr/mesh/D005732?mesh_terms=Delphi+Technique&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Gangliosides", "description": "Peut-on prévenir les gangliosidoses ?\nLe conseil génétique est-il recommandé ?\nLes vaccinations peuvent-elles aider ?\nL'alimentation peut-elle jouer un rôle préventif ?\nLes tests de dépistage sont-ils utiles ?", "url": "https://questionsmedicales.fr/mesh/D005732?mesh_terms=Delphi+Technique&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Gangliosides", "description": "Quels traitements existent pour les gangliosidoses ?\nLa thérapie génique est-elle une option ?\nLes médicaments peuvent-ils aider ?\nY a-t-il des traitements expérimentaux disponibles ?\nLe soutien nutritionnel est-il important ?", "url": "https://questionsmedicales.fr/mesh/D005732?mesh_terms=Delphi+Technique&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Gangliosides", "description": "Quelles complications peuvent survenir ?\nLes gangliosidoses peuvent-elles entraîner des handicaps ?\nY a-t-il un risque accru de maladies associées ?\nLes complications sont-elles réversibles ?\nComment gérer les complications ?", "url": "https://questionsmedicales.fr/mesh/D005732?mesh_terms=Delphi+Technique&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Gangliosides", "description": "Quels sont les facteurs de risque des gangliosidoses ?\nLes origines ethniques influencent-elles le risque ?\nLes facteurs environnementaux jouent-ils un rôle ?\nLes antécédents médicaux familiaux sont-ils significatifs ?\nLes mutations génétiques sont-elles héréditaires ?", "url": "https://questionsmedicales.fr/mesh/D005732?mesh_terms=Delphi+Technique&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une maladie liée aux gangliosides ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur des tests génétiques, des analyses biochimiques et des biopsies." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour détecter les gangliosides ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests sanguins et des analyses de tissus peuvent être effectués pour détecter les gangliosides." } }, { "@type": "Question", "name": "Les symptômes peuvent-ils indiquer un problème de gangliosides ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des symptômes neurologiques ou musculaires peuvent suggérer une dysfonction des gangliosides." } }, { "@type": "Question", "name": "Quelle imagerie est utile pour évaluer les gangliosides ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "L'IRM peut aider à visualiser les anomalies cérébrales associées aux gangliosidoses." } }, { "@type": "Question", "name": "Les antécédents familiaux sont-ils importants pour le diagnostic ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les antécédents familiaux de maladies génétiques peuvent orienter le diagnostic." } }, { "@type": "Question", "name": "Quels sont les symptômes courants des gangliosidoses ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des troubles neurologiques, des retards de développement et des problèmes moteurs." } }, { "@type": "Question", "name": "Les gangliosides affectent-ils le système nerveux ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les gangliosides sont essentiels pour le fonctionnement normal du système nerveux." } }, { "@type": "Question", "name": "Peut-on observer des symptômes cutanés ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Certaines gangliosidoses peuvent provoquer des lésions cutanées ou des anomalies pigmentaires." } }, { "@type": "Question", "name": "Les troubles cognitifs sont-ils liés aux gangliosides ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles cognitifs peuvent survenir en raison de l'accumulation de gangliosides dans le cerveau." } }, { "@type": "Question", "name": "Les douleurs musculaires sont-elles un symptôme ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des douleurs musculaires peuvent être présentes en raison de l'atteinte des gangliosides." } }, { "@type": "Question", "name": "Peut-on prévenir les gangliosidoses ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est limitée, mais le dépistage génétique peut aider à identifier les porteurs." } }, { "@type": "Question", "name": "Le conseil génétique est-il recommandé ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le conseil génétique est conseillé pour les familles à risque de gangliosidoses." } }, { "@type": "Question", "name": "Les vaccinations peuvent-elles aider ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Les vaccinations ne préviennent pas les gangliosidoses, mais protègent contre d'autres maladies." } }, { "@type": "Question", "name": "L'alimentation peut-elle jouer un rôle préventif ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée peut soutenir la santé générale, mais ne prévient pas les gangliosidoses." } }, { "@type": "Question", "name": "Les tests de dépistage sont-ils utiles ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les tests de dépistage peuvent identifier les porteurs de mutations génétiques." } }, { "@type": "Question", "name": "Quels traitements existent pour les gangliosidoses ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent la thérapie enzymatique, la gestion des symptômes et le soutien psychologique." } }, { "@type": "Question", "name": "La thérapie génique est-elle une option ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "La thérapie génique est en cours d'étude pour certaines gangliosidoses, mais n'est pas encore standard." } }, { "@type": "Question", "name": "Les médicaments peuvent-ils aider ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Certains médicaments peuvent soulager les symptômes, mais ne traitent pas la cause sous-jacente." } }, { "@type": "Question", "name": "Y a-t-il des traitements expérimentaux disponibles ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des essais cliniques sont en cours pour de nouveaux traitements des gangliosidoses." } }, { "@type": "Question", "name": "Le soutien nutritionnel est-il important ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un soutien nutritionnel peut aider à améliorer la qualité de vie des patients." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des troubles neurologiques graves, des infections et des problèmes respiratoires." } }, { "@type": "Question", "name": "Les gangliosidoses peuvent-elles entraîner des handicaps ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines gangliosidoses peuvent entraîner des handicaps physiques ou mentaux permanents." } }, { "@type": "Question", "name": "Y a-t-il un risque accru de maladies associées ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les patients peuvent avoir un risque accru de maladies auto-immunes ou métaboliques." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "La plupart des complications des gangliosidoses ne sont pas réversibles et nécessitent une gestion." } }, { "@type": "Question", "name": "Comment gérer les complications ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "La gestion des complications nécessite une approche multidisciplinaire incluant médecins et thérapeutes." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque des gangliosidoses ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, des mutations génétiques et des origines ethniques spécifiques." } }, { "@type": "Question", "name": "Les origines ethniques influencent-elles le risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines populations, comme les Ashkénazes, ont un risque plus élevé de gangliosidoses." } }, { "@type": "Question", "name": "Les facteurs environnementaux jouent-ils un rôle ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, les facteurs environnementaux ne sont pas clairement établis comme des risques." } }, { "@type": "Question", "name": "Les antécédents médicaux familiaux sont-ils significatifs ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents médicaux de maladies métaboliques augmentent le risque de gangliosidoses." } }, { "@type": "Question", "name": "Les mutations génétiques sont-elles héréditaires ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les mutations génétiques responsables des gangliosidoses sont souvent héréditaires." } } ] } ] }

Sources (10000 au total)

Using the Behaviour Change Wheel and modified Delphi method to identify behavioural change techniques for improving adherence to smoking cessation medications.

Medication adherence is a crucial component of the pharmacological treatment of smoking. Previous interventions targeted to improve adherence to smoking cessation medications (SCMs) were designed usin... Recommendations for the design of intervention strategies were based on the BCW guide and six studies conducted by the research team. Factors related to healthcare providers and consumers (person maki... Following a stepped approach, an adherence support wheel was designed to guide implementation strategies and programmes. Thirteen intervention strategies were selected. The selected interventions incl... The BCW guide and a modified Delphi were applied successfully to design interventions tailored to improve adherence to SCMs. Improving adherence to SCMs requires a comprehensive intervention approach ...

Development of a decision support tool to prevent community acquired pressure injuries for use in the spinal cord injury clinic using the delphi technique.

Delphi Technique.... Describe the development of a decision support tool to prevent community-acquired pressure injuries (CAPrIs) in individuals with spinal cord injury (SCI) for use in SCI clinics, called the Community-A... Veteran Health Administration Hospital, Chicago, Illinois, USA.... Concept mapping of current pressure injury (PrI) guidelines and qualitative research describing risks, actions, and resources needed to prevent CAPrIs associated with SCI were used to develop 40 veter... Panelists were 60% female, 62% White, 33% veterans with SCI or caregivers, 33% wound care certified with a mean age of 59 years. Two survey rounds were required for consensus for 41 Item and 38 Action... The CAPP-FIT could become a useful tool for Veterans living with SCI, caregivers, and SCI providers....

Delphi studies in social and health sciences-Recommendations for an interdisciplinary standardized reporting (DELPHISTAR). Results of a Delphi study.

While different proposals exist for a guideline on reporting Delphi studies, none of them has yet established itself in the health and social sciences and across the range of Delphi variants. This see... In an international Delphi procedure, Delphi experts were surveyed online in three rounds to find consensus on a reporting guideline for Delphi studies in the health and social sciences. The responden... 1,072 experts were invited to participate. A total of 91 experts completed the first Delphi round, 69 experts the second round, and 56 experts the third round. Of the 65 items in the first draft of th... We assume a high level of acceptance and interdisciplinary suitability regarding the reporting guideline presented here and referred to as the "Delphi studies in social and health sciences-recommendat...

Factors Associated with Non-Adherence to Self-Management Among Patients with Chronic Obstructive Pulmonary Disease: A Survey Using the Delphi Technique and Analytic Hierarchy Process.

The relevant factors and patterns of non-adherence to self-management among patients with chronic obstructive pulmonary disease (COPD) need to be elucidated to improve self-management.... This study was a survey to prioritize the relevance of factors associated with non-adherence to COPD self-management using the Delphi technique and analytic hierarchy process (AHP).... A total of 15 expert panels were established to determine the priority of relevant factors in a three-round Delphi survey and an AHP. To develop the preliminary conceptual framework for non-adherence ... In developing the preliminary conceptual framework, 8 factor categories and 53 factors were identified as relevant to non-adherence to COPD self-management. Of the 53 factors, 22 factors with a CVR of... Through consensus decision-making by experts, 14 factors were identified as relevant factors associated with non-adherence to COPD self-management. A hierarchical and systematic framework incorporatin...

Delphi method applicability in drug foresight.

The aim of the current study was to assess the accuracy of expert predictions, which were derived using a Delphi panel foresight study between 2009 and 2011, on a variety of drug-related topics in Fin... The material used to evaluate the accuracy of the predictions consists of published reports on statistics, survey results, official register data, wastewater analyses and official documents. Whenever ... Between 2009 and 2011, the majority - but not all - of the experts accurately predicted an increase in drug use. Indeed, more people experimented with or used drugs, and more drug residues were found ... It seems to have been easier for the experts to foresee the continuation of existing trends, e.g., increasing use of drugs or widening approval of drugs, than to predict possible changes in the popula...

Moral distress in midwifery practice: A Delphi study.

Moral distress is a psychological concept that describes the harm associated with actions or inactions that oppose an individuals' moral beliefs. Moral distress is linked to moral compromise in the wo... The aim of this study was to develop a list of situational and outcome statements associated with moral compromise and levels of moral distress in midwifery to inform the development of a tool to meas... This e-Delphi study was the third stage of a sequential exploratory mixed-methods study. Using an online strategy, three iterative rounds of e-Delphi were collected and analysed for consensus on situa... Twenty participants contributed across the three rounds. Consensus was met in 40 morally compromising situation statements. The highest level of consensus related to excessive workloads and the associ... This is the first study to use a consensus method to establish different levels of moral compromise, frustration, distress, and injury in midwifery practice. The findings of this study contribute to a...

Consensus on Nasal Irrigation in Infants: A Delphi Study.

Nasal irrigation is regularly used in infants to relieve upper airway symptoms. However, because there is no consensus on good practice, nasal irrigation in infants is described and applied heterogene... The aim of this study was to establish consensus regarding the use of nasal irrigation in infants.... A panel of Belgian physiotherapists and physicians experienced in performing nasal irrigation in infants were surveyed using the Delphi technique. Three survey rounds were used. Participants rated the... Thirty experts (12 physicians and 18 physiotherapists) completed all 3 questionnaires. Consensus was achieved for 47 of 75 statements (63%) distributed over the following domains: "contraindications,"... This study provides the first well-constructed consensus on good practice on nasal irrigation in infants. Consensus on several statements across different domains were established but require validati...

Paracetamol and ibuprofen fixed-dose combination for the management of acute mild-to-moderate pain in children: strengthening and enhancing of result of Nominal Group Technique through Delphi consensus.

Paracetamol and ibuprofen are the most commonly used drugs for pain treatment in children and their combination has shown improved analgesic effect compared to treatment with either drug alone. Curren... The survey, conducted with Delphi methodology, involved 75 hospital and outpatient pediatricians with clinical experience in the management of pain in children. Pediatricians involved were asked to va... The results confirm the importance of the fixed-dose paracetamol and ibuprofen combination for the control of mild-to-moderate acute pain in children. Particularly, this association seems to be approp... Both the NGT consensus and the broader Delphi consensus confirm the usefulness of the paracetamol-ibuprofen fixed-dose combination in pediatric pain. This is attributed to its superior effectiveness c...

International standardization and optimization group for intersphincteric resection (ISOG-ISR): modified Delphi consensus on anatomy, definition, indication, surgical technique, specimen description and functional outcome.

Intersphincteric resection (ISR) is an oncologically complex operation for very low-lying rectal cancers. Yet, definition, anatomical description, operative indications and operative approaches to ISR... A modified Delphi approach with three rounds of questionnaire was adopted. A total of 29 international experts from 11 countries were recruited for this study. Six domains with a total of 37 statement... Three rounds of questionnaire were performed (response rate 100%, 89.6%, 89.6%). Agreement (≥80%) reached standardization on 36 statements.... This study provides an international expert consensus-based definition and standardization of ISR. This is the first study standardizing terminology and definition of deep pelvis/anal canal anatomy fr...

Home exercises for neck pain: A Delphi survey.

The current context of the COVID-19 pandemic has demonstrated the need for home exercise strategies for the relief of neck pain, which, in recent times, has increased. However, there is a gap regardin... This was an observational study conducted in three stages: (1) Developing an online search of databases for articles on neck pain exercises. (2) Validating a panel of 12 physical therapists, using the... A protocol was developed with the principles of neck and scapular stabilization and upper limb movements, for a period of 4 weeks. Nine physical therapists completed two rounds online, and all items i... A 4-week home exercise protocol was created based on the best evidence in the literature, was validated by physical therapists and adapted for the population with neck pain. It proved to be an underst... GOV: (NCT04187001)....