{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Hyperplasie lymphoïde angiofolliculaire : Questions médicales les plus fréquentes",
"headline": "Hyperplasie lymphoïde angiofolliculaire : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Hyperplasie lymphoïde angiofolliculaire : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-01-26",
"dateModified": "2025-04-20",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Hyperplasie lymphoïde angiofolliculaire"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Syndromes lymphoprolifératifs",
"url": "https://questionsmedicales.fr/mesh/D008232",
"about": {
"@type": "MedicalCondition",
"name": "Syndromes lymphoprolifératifs",
"code": {
"@type": "MedicalCode",
"code": "D008232",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C20.683.515"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Hyperplasie lymphoïde angiofolliculaire",
"alternateName": "Castleman Disease",
"code": {
"@type": "MedicalCode",
"code": "D005871",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "David C Fajgenbaum",
"url": "https://questionsmedicales.fr/author/David%20C%20Fajgenbaum",
"affiliation": {
"@type": "Organization",
"name": "Center for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Philadelphia, PA, USA."
}
},
{
"@type": "Person",
"name": "Angela Dispenzieri",
"url": "https://questionsmedicales.fr/author/Angela%20Dispenzieri",
"affiliation": {
"@type": "Organization",
"name": "Division of Hematology, Mayo Clinic, Rochester, MN; and."
}
},
{
"@type": "Person",
"name": "Kazue Takai",
"url": "https://questionsmedicales.fr/author/Kazue%20Takai",
"affiliation": {
"@type": "Organization",
"name": "Department of Hematology, Niigata City General Hospital, Niigata, Japan."
}
},
{
"@type": "Person",
"name": "Eric Oksenhendler",
"url": "https://questionsmedicales.fr/author/Eric%20Oksenhendler",
"affiliation": {
"@type": "Organization",
"name": "Département d'immunologie Clinique, Hôpital Saint-Louis, Université de Paris, Paris, France."
}
},
{
"@type": "Person",
"name": "Wei Wang",
"url": "https://questionsmedicales.fr/author/Wei%20Wang",
"affiliation": {
"@type": "Organization",
"name": "Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Exercise testing to guide safe discharge from hospital in COVID-19: a scoping review to identify candidate tests.",
"datePublished": "2023-10-31",
"url": "https://questionsmedicales.fr/article/37907292",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1136/bmjopen-2022-068169"
}
},
{
"@type": "ScholarlyArticle",
"name": "Guidance and standard operating procedures for functional exercise testing in cystic fibrosis.",
"datePublished": "2023-08-09",
"url": "https://questionsmedicales.fr/article/37558263",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1183/16000617.0029-2023"
}
},
{
"@type": "ScholarlyArticle",
"name": "Cardiopulmonary exercise testing for patients with anorexia nervosa: a case-control study.",
"datePublished": "2022-10-22",
"url": "https://questionsmedicales.fr/article/36271269",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s40519-022-01492-6"
}
},
{
"@type": "ScholarlyArticle",
"name": "Cardiopulmonary Exercise Testing Interpretation in Athletes: What the Cardiologist Should Know.",
"datePublished": "2022-10-21",
"url": "https://questionsmedicales.fr/article/36368812",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ccl.2022.08.006"
}
},
{
"@type": "ScholarlyArticle",
"name": "Cardiopulmonary exercise testing in long covid shows the presence of dysautonomia or chronotropic incompetence independent of subjective exercise intolerance and fatigue.",
"datePublished": "2024-08-08",
"url": "https://questionsmedicales.fr/article/39117999",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s12872-024-04081-w"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Maladies du système immunitaire",
"item": "https://questionsmedicales.fr/mesh/D007154"
},
{
"@type": "ListItem",
"position": 3,
"name": "Syndromes immunoprolifératifs",
"item": "https://questionsmedicales.fr/mesh/D007160"
},
{
"@type": "ListItem",
"position": 4,
"name": "Syndromes lymphoprolifératifs",
"item": "https://questionsmedicales.fr/mesh/D008232"
},
{
"@type": "ListItem",
"position": 5,
"name": "Hyperplasie lymphoïde angiofolliculaire",
"item": "https://questionsmedicales.fr/mesh/D005871"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Hyperplasie lymphoïde angiofolliculaire - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Hyperplasie lymphoïde angiofolliculaire",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-18",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Hyperplasie lymphoïde angiofolliculaire",
"description": "Comment diagnostiquer la maladie de Castleman ?\nQuels tests sont utilisés pour confirmer le diagnostic ?\nQuels signes cliniques indiquent une hyperplasie lymphoïde ?\nLa maladie de Castleman est-elle toujours symptomatique ?\nQuel rôle joue l'imagerie dans le diagnostic ?",
"url": "https://questionsmedicales.fr/mesh/D005871?mesh_terms=Exercise+Test&page=5#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Hyperplasie lymphoïde angiofolliculaire",
"description": "Quels sont les symptômes courants de la maladie de Castleman ?\nLa fatigue est-elle un symptôme de cette maladie ?\nPeut-on avoir des sueurs nocturnes avec cette maladie ?\nLes symptômes varient-ils d'un patient à l'autre ?\nY a-t-il des symptômes spécifiques à la forme multicentrique ?",
"url": "https://questionsmedicales.fr/mesh/D005871?mesh_terms=Exercise+Test&page=5#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Hyperplasie lymphoïde angiofolliculaire",
"description": "Peut-on prévenir la maladie de Castleman ?\nY a-t-il des facteurs de risque identifiés ?\nLes habitudes de vie influencent-elles le risque ?\nLes vaccinations peuvent-elles aider ?\nLe dépistage précoce est-il utile ?",
"url": "https://questionsmedicales.fr/mesh/D005871?mesh_terms=Exercise+Test&page=5#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Hyperplasie lymphoïde angiofolliculaire",
"description": "Quels traitements sont disponibles pour la maladie de Castleman ?\nLa radiothérapie est-elle utilisée dans le traitement ?\nLes corticostéroïdes sont-ils efficaces ?\nQuel est le rôle des thérapies ciblées ?\nLa surveillance est-elle nécessaire après le traitement ?",
"url": "https://questionsmedicales.fr/mesh/D005871?mesh_terms=Exercise+Test&page=5#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Hyperplasie lymphoïde angiofolliculaire",
"description": "Quelles complications peuvent survenir avec Castleman ?\nLa maladie de Castleman peut-elle entraîner des infections ?\nY a-t-il un risque de cancer associé ?\nComment gérer les complications ?\nLes complications affectent-elles le pronostic ?",
"url": "https://questionsmedicales.fr/mesh/D005871?mesh_terms=Exercise+Test&page=5#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Hyperplasie lymphoïde angiofolliculaire",
"description": "Quels sont les principaux facteurs de risque ?\nL'âge influence-t-il le risque de Castleman ?\nLe sexe joue-t-il un rôle dans le risque ?\nLes antécédents familiaux sont-ils un facteur ?\nLe mode de vie affecte-t-il le risque ?",
"url": "https://questionsmedicales.fr/mesh/D005871?mesh_terms=Exercise+Test&page=5#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer la maladie de Castleman ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur l'examen clinique, l'imagerie et la biopsie des ganglions lymphatiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour confirmer le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins, des échographies et des IRM peuvent être utilisés pour évaluer l'étendue de la maladie."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques indiquent une hyperplasie lymphoïde ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des ganglions lymphatiques enflés, de la fièvre et des sueurs nocturnes peuvent indiquer la maladie."
}
},
{
"@type": "Question",
"name": "La maladie de Castleman est-elle toujours symptomatique ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, certains patients peuvent être asymptomatiques, rendant le diagnostic plus difficile."
}
},
{
"@type": "Question",
"name": "Quel rôle joue l'imagerie dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'imagerie aide à visualiser les ganglions lymphatiques et à évaluer leur taille et leur nombre."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes courants de la maladie de Castleman ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des ganglions lymphatiques enflés, de la fièvre, et des douleurs abdominales."
}
},
{
"@type": "Question",
"name": "La fatigue est-elle un symptôme de cette maladie ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la fatigue est fréquente et peut résulter de l'inflammation et de l'anémie associées."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des sueurs nocturnes avec cette maladie ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les sueurs nocturnes sont un symptôme courant chez les patients atteints de Castleman."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils d'un patient à l'autre ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent varier en fonction du type et de la gravité de la maladie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes spécifiques à la forme multicentrique ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la forme multicentrique peut entraîner des symptômes systémiques plus prononcés."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir la maladie de Castleman ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de méthode de prévention connue pour la maladie de Castleman."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs de risque identifiés ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs comme l'infection par le VIH et certaines maladies auto-immunes peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les habitudes de vie influencent-elles le risque ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des habitudes de vie saines peuvent aider à réduire le risque de maladies en général."
}
},
{
"@type": "Question",
"name": "Les vaccinations peuvent-elles aider ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Bien que les vaccinations ne préviennent pas Castleman, elles protègent contre d'autres infections."
}
},
{
"@type": "Question",
"name": "Le dépistage précoce est-il utile ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le dépistage précoce n'est pas standardisé pour Castleman, mais un suivi médical régulier est conseillé."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour la maladie de Castleman ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent la chirurgie, la chimiothérapie et les thérapies ciblées."
}
},
{
"@type": "Question",
"name": "La radiothérapie est-elle utilisée dans le traitement ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la radiothérapie peut être utilisée pour traiter les formes localisées de la maladie."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les corticostéroïdes peuvent réduire l'inflammation et soulager certains symptômes."
}
},
{
"@type": "Question",
"name": "Quel est le rôle des thérapies ciblées ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les thérapies ciblées visent des molécules spécifiques pour inhiber la croissance tumorale."
}
},
{
"@type": "Question",
"name": "La surveillance est-elle nécessaire après le traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier est essentiel pour détecter toute récidive ou complication."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec Castleman ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent l'insuffisance organique, l'infection et le développement de lymphomes."
}
},
{
"@type": "Question",
"name": "La maladie de Castleman peut-elle entraîner des infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'immunosuppression liée à la maladie peut augmenter le risque d'infections."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque de cancer associé ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients peuvent avoir un risque accru de développer des lymphomes ou d'autres cancers."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications nécessite une approche multidisciplinaire et un suivi régulier."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles le pronostic ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la présence de complications peut aggraver le pronostic et compliquer le traitement."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections virales, notamment par le VIH, et certaines maladies auto-immunes sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque de Castleman ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la maladie peut survenir à tout âge, mais elle est plus fréquente chez les jeunes adultes."
}
},
{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études montrent que les hommes peuvent être plus susceptibles de développer la maladie."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils un facteur ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'y a pas de preuve solide que les antécédents familiaux augmentent le risque de Castleman."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut réduire le risque de nombreuses maladies, mais son impact sur Castleman est incertain."
}
}
]
}
]
}
We aimed to identify exercise tests that have been validated to support a safe discharge to home in patients with or without COVID-19....
Scoping review, using PRISMA-ScR reporting standards. Medline, PubMed, AMED, Embase, CINAHL and LitCovid databases were searched between 16 and 22 February 2021, with studies included from any publica...
Short exercise tests....
Safe discharge from hospital, readmission rate, length of hospital stay, mortality. Secondary outcomes measures: safety, feasibility and reliability....
Of 1612 original records screened, 19 studies were included in the analysis. These used a variety of exercise tests in patients with chronic obstructive pulmonary disease, suspected pulmonary embolism...
Further research is needed to aid clinical decision-making at discharge from hospital....
Regular exercise testing is recommended for all people with cystic fibrosis (PwCF). A range of validated tests, which integrate both strength and aerobic function, are available and increasingly being...
Patients with anorexia nervosa (AN) require appropriate nutrient therapy and physical activity management. Eating disorder treatment guidelines do not include safe, evidence-based intensity criteria f...
CPX was performed with 14 female patients with AN admitted to a specialized eating disorder unit between 2015 and 2019. Their anaerobic threshold (AT) was determined by assessing their exercise tolera...
The AT of the AN group (BMI: 15.7 [Mean] ± 1.8 standard deviation [SD]) was significantly lower than that of the HC group (BMI: 19.7 ± 1.8) (AN: 10.0 ± 1.8 vs. HC: 15.2 ± 3.0 ml/kg/min, P < 0.001). AT...
This study showed that AT and AT-METS were lower in patients with AN than in HC. Patients with AN should be prescribed light-intensity aerobic exercise, and the current findings may help develop futur...
III: Evidence obtained from case-control analytic studies....
The noninvasive assessment of oxygen consumption, carbon dioxide production, and ventilation during a cardiopulmonary exercise test (CPET) provides insight into the cardiovascular, pulmonary, and meta...
After COVID-19 infection, 10-20% of patients suffer from varying symptoms lasting more than 12 weeks (Long COVID, LC). Exercise intolerance and fatigue are common in LC. The aim was to measure the max...
Cardiopulmonary exercise test was conducted on 101 LC patients, who were admitted to exercise testing. The majority of them (86%) had been treated at home during their acute COVID-19 infection. Peak o...
The measurements were performed in mean 12.7 months (SD 5.75) after COVID-19 infection in patients with exercise intolerance (group EI, 19 patients), fatigue (group F, 31 patients), their combination ...
This study on LC patients with different symptoms showed that cardiopulmonary exercise capacity was in mean normal, with increased sympathetic activity in most patients. However, we identified subgrou...
Using exercise protocols at a fixed rating of perceived effort (RPE) is a useful method for exploring the psychophysical influences on exercise performance. However, studies that have employed this pr...
Eight recreationally active cyclists completed two identical ramped incremental trials on a cycle ergometer to identify gas exchange threshold (GET). A linear regression model plotted RPE responses du...
All performance and gas parameters showed excellent levels of test-retest reliability (ICCs = > .900) across both intensities. Performance, gas-related measures, and heart rate averaged over the entir...
Recreationally active cyclists can reliably replicate fixed perceived effort exercise across multiple visits when RPE is aligned to physiological thresholds. Some evidence suggests that exercise at RP...
Pulmonary arterial hypertension (PAH) is a severe, high mortality and progressive disease. Early diagnosis and treatment improves the prognosis. Patients with scleroderma disease presents high risk of...
Prospective study of 52 consecutive patients diagnosed of scleroderma in our health area, during 2 years (2018 and 2019). All of them undergo CPET, in addition to the annual systematic screening. Sens...
Fifty-two CPET were performed, of which 16 suggested PAH. Resting RHC confirmed PAH in 5 patients and exercise RHC in 7 (diagnostic sensitivity of CPET together with rest and exercise catheterization ...
CPET and exercise RHC could detect PAH earlier than established screening in patients with scleroderma disease, allowing early diagnosis....
To establish a pre-test probability model of coronary heart disease (CHD) combined with cardiopulmonary exercise test (CPET) indexes and to compare the clinical effectiveness with Duke clinical score ...
Cardiopulmonary exercise testing (CPET) may provide prognostically valuable information during follow-up after pulmonary embolism (PE). Our objective was to investigate the association of patterns and...
In a prospective cohort study of unselected consecutive all-comers with PE, survivors of the index acute event underwent 3- and 12-month follow-ups, including CPET. We defined cardiopulmonary limitati...
Overall, 396 patients were included. At 3 months, prevalence of cardiopulmonary limitation and deconditioning was 50.1% (34.7% mild/moderate; 15.4% severe) and 12.1%, respectively; at 12 months, it wa...
Abnormal exercise capacity of cardiopulmonary origin is frequent after PE, being associated with clinical and haemodynamic impairment as well as long-term QoL reduction. CPET can be considered for sel...
Dysfunctional breathing (DB) is a common, but largely underappreciated, cause of chronic dyspnoea. Under visual inspection, most subjects with DB present with larger sequential changes in ventilation ...
Twenty chronically dyspnoeic subjects with DB and 10 age- and sex-matched controls performed CPET on a cycle ergometer. Cut-offs to indicate increased V̇E, VT, f, and f/VT ratio variability (Δ = highe...
Subjects with DB presented with increased V̇E, higher ventilatory variability, higher dyspnoea burden, and lower exercise capacity compared to controls (p < 0.05). ΔV̇E...
This study provides objective criteria to indicate increased ventilatory variability during incremental CPET in dyspnoeic subjects with DB. Large variability in breathing frequency seems particularly ...