Titre : Glycosylation

Glycosylation : Questions médicales fréquentes

Termes MeSH sélectionnés :

Sleep Duration
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indiquent une anomalie de glycosylation ?\nPeut-on utiliser l'imagerie pour diagnostiquer la glycosylation ?", "url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Sleep+Duration&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Glycosylation", "description": "Quels sont les symptômes d'une glycosylation anormale ?\nLa fatigue est-elle un symptôme de glycosylation ?\nLes troubles digestifs sont-ils liés à la glycosylation ?\nY a-t-il des symptômes cutanés associés ?\nLes problèmes de croissance sont-ils fréquents ?", "url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Sleep+Duration&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Glycosylation", "description": "Peut-on prévenir les anomalies de glycosylation ?\nLe dépistage génétique est-il recommandé ?\nLes vaccinations aident-elles à prévenir les complications ?\nY a-t-il des conseils diététiques préventifs ?\nLes consultations médicales régulières sont-elles importantes ?", "url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Sleep+Duration&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Glycosylation", "description": "Quels traitements existent pour les anomalies de glycosylation ?\nLes enzymes de remplacement sont-elles efficaces ?\nLa diététique joue-t-elle un rôle dans le traitement ?\nLes médicaments immunosuppresseurs sont-ils utilisés ?\nY a-t-il des traitements expérimentaux disponibles ?", "url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Sleep+Duration&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Glycosylation", "description": "Quelles sont les complications possibles de la glycosylation ?\nLes infections sont-elles fréquentes chez ces patients ?\nY a-t-il des risques de cancer associés ?\nLes troubles cardiovasculaires sont-ils liés ?\nLes complications psychologiques sont-elles possibles ?", "url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Sleep+Duration&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Glycosylation", "description": "Quels sont les facteurs de risque pour les anomalies de glycosylation ?\nL'âge joue-t-il un rôle dans la glycosylation ?\nLes facteurs environnementaux influencent-ils la glycosylation ?\nLes maladies métaboliques augmentent-elles le risque ?\nLe sexe a-t-il un impact sur la glycosylation ?", "url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Sleep+Duration&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une anomalie de glycosylation ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques et des analyses de glycoprotéines sont utilisés." } }, { "@type": "Question", "name": "Quels tests sanguins sont utilisés pour la glycosylation ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests de glycoprotéines et les profils glycosylés sont courants." } }, { "@type": "Question", "name": "Les biopsies sont-elles utiles pour la glycosylation ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les biopsies tissulaires peuvent révéler des anomalies de glycosylation." } }, { "@type": "Question", "name": "Quels symptômes indiquent une anomalie de glycosylation ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des retards de développement, des problèmes immunitaires et des anomalies neurologiques." } }, { "@type": "Question", "name": "Peut-on utiliser l'imagerie pour diagnostiquer la glycosylation ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'imagerie n'est pas spécifique, mais peut aider à évaluer des complications." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une glycosylation anormale ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des troubles neurologiques, des infections fréquentes et des anomalies physiques." } }, { "@type": "Question", "name": "La fatigue est-elle un symptôme de glycosylation ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la fatigue peut être un symptôme associé à des troubles de glycosylation." } }, { "@type": "Question", "name": "Les troubles digestifs sont-ils liés à la glycosylation ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains troubles digestifs peuvent être liés à des anomalies de glycosylation." } }, { "@type": "Question", "name": "Y a-t-il des symptômes cutanés associés ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des éruptions cutanées et des anomalies de la peau peuvent survenir." } }, { "@type": "Question", "name": "Les problèmes de croissance sont-ils fréquents ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des retards de croissance peuvent être observés chez les patients affectés." } }, { "@type": "Question", "name": "Peut-on prévenir les anomalies de glycosylation ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est difficile, mais un diagnostic précoce peut aider à gérer les symptômes." } }, { "@type": "Question", "name": "Le dépistage génétique est-il recommandé ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le dépistage génétique peut être utile pour les familles à risque." } }, { "@type": "Question", "name": "Les vaccinations aident-elles à prévenir les complications ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les vaccinations peuvent réduire le risque d'infections chez ces patients." } }, { "@type": "Question", "name": "Y a-t-il des conseils diététiques préventifs ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée peut soutenir la santé globale et le système immunitaire." } }, { "@type": "Question", "name": "Les consultations médicales régulières sont-elles importantes ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles permettent de surveiller l'évolution et d'ajuster les traitements." } }, { "@type": "Question", "name": "Quels traitements existent pour les anomalies de glycosylation ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des thérapies de soutien et des interventions spécifiques selon les symptômes." } }, { "@type": "Question", "name": "Les enzymes de remplacement sont-elles efficaces ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent être efficaces pour certaines formes de maladies liées à la glycosylation." } }, { "@type": "Question", "name": "La diététique joue-t-elle un rôle dans le traitement ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des régimes spécifiques peuvent aider à gérer certains symptômes." } }, { "@type": "Question", "name": "Les médicaments immunosuppresseurs sont-ils utilisés ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent être prescrits pour traiter des complications immunitaires." } }, { "@type": "Question", "name": "Y a-t-il des traitements expérimentaux disponibles ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des essais cliniques sont en cours pour de nouvelles thérapies ciblées." } }, { "@type": "Question", "name": "Quelles sont les complications possibles de la glycosylation ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des troubles neurologiques, des infections et des problèmes de croissance." } }, { "@type": "Question", "name": "Les infections sont-elles fréquentes chez ces patients ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les patients peuvent être plus susceptibles aux infections en raison d'un système immunitaire affaibli." } }, { "@type": "Question", "name": "Y a-t-il des risques de cancer associés ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Certaines anomalies de glycosylation peuvent augmenter le risque de cancers spécifiques." } }, { "@type": "Question", "name": "Les troubles cardiovasculaires sont-ils liés ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles cardiovasculaires peuvent survenir chez certains patients." } }, { "@type": "Question", "name": "Les complications psychologiques sont-elles possibles ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des complications psychologiques comme l'anxiété peuvent être observées." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les anomalies de glycosylation ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les antécédents familiaux et certaines mutations génétiques sont des facteurs de risque." } }, { "@type": "Question", "name": "L'âge joue-t-il un rôle dans la glycosylation ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Certaines anomalies peuvent se manifester plus tôt dans l'enfance, mais d'autres plus tard." } }, { "@type": "Question", "name": "Les facteurs environnementaux influencent-ils la glycosylation ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs environnementaux peuvent interagir avec des prédispositions génétiques." } }, { "@type": "Question", "name": "Les maladies métaboliques augmentent-elles le risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines maladies métaboliques peuvent être associées à des anomalies de glycosylation." } }, { "@type": "Question", "name": "Le sexe a-t-il un impact sur la glycosylation ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines anomalies peuvent avoir des manifestations différentes selon le sexe." } } ] } ] }

Sources (10000 au total)

Sleep Duration Is Associated With Subclinical Carotid Plaque Burden.

Sleep duration is associated with stroke risk and is 1 of 8 essential components of cardiovascular health according to the American Heart Association. As stroke disproportionately burdens Black and Hi... NOMAS is a study of community-dwelling adults. Self-reported nightly sleep duration and daytime sleepiness were collected between 2006 and 2011. Carotid plaque presence, total plaque area, and intima-... The sample (n=1553) had a mean age of 64.7±8.5 years and was 61.9% female, 64.8% Hispanic, and 18.2% non-Hispanic Black. Of the sample, 55.6% had carotid plaque, 22.3% reported nightly short sleep (<7... The association between long sleep and subclinical carotid atherosclerosis may explain prior associations between long sleep and stroke....

Objective Sleep Duration and All-Cause Mortality Among People With Obstructive Sleep Apnea.

The association between sleep duration and all-cause mortality remains unclear among people with obstructive sleep apnea (OSA).... To explore whether there is an association between sleep duration and all-cause mortality among people with OSA.... This cohort study investigated participants with OSA from the Sleep Heart Health Study (SHHS) in which participants were enrolled between 1995 and 1998 with questionnaires and polysomnography (PSG) as... Participants were divided into 4 groups with objective sleep duration of (1) at least 7 hours, (2) 6 to less than 7 hours, (3) 5 to less than 6 hours, and (4) less than 5 hours, which was determined b... All-cause mortality was defined as deaths from any cause and its risk was compared among 4 OSA groups using Cox regression models.... A total of 2574 participants with OSA were included (1628 [63.2%] men and 946 [36.8%] women; mean [SD] age, 65.4 [10.7] years; 211 [8.2%] Black, 2230 [86.6%] White, 133 [5.2%] other race). Overall, 68... In this cohort study of 2574 participants with OSA, those with shorter objective sleep duration had higher risk of all-cause mortality independent of AHI compared with those sleeping at least 7 hours....

Insomnia, Poor Sleep Quality and Sleep Duration, and Risk for COVID-19 Infection and Hospitalization.

Medical comorbidities increase the risk of severe acute COVID-19 illness. Although sleep problems are common after COVID-19 infection, it is unclear whether insomnia, poor sleep quality, and extremely... The study used a cross-sectional survey of a diverse sample of 19,926 US adults.... COVID-19 infection and hospitalization prevalence rates were 40.1% and 2.9%, respectively. Insomnia and poor sleep quality were reported in 19.8% and 40.1%, respectively. In logistic regression models... In a general population sample, poor sleep quality and extremes of sleep duration are associated with greater odds of having had a COVID-19 infection; poor sleep quality was associated with an increas...

Adapting shift work schedules for sleep quality, sleep duration, and sleepiness in shift workers.

Shift work is associated with insufficient sleep, which can compromise worker alertness with ultimate effects on occupational health and safety. Adapting shift work schedules may reduce adverse occupa... To assess the effects of shift schedule adaptation on sleep quality, sleep duration, and sleepiness among shift workers.... We searched CENTRAL, PubMed, Embase, and eight other databases on 13 December 2020, and again on 20 April 2022, applying no language restrictions.... We included randomised controlled trials (RCTs) and non-RCTs, including controlled before-after (CBA) trials, interrupted time series, and cross-over trials. Eligible trials evaluated any of the follo... Two review authors independently screened the titles and abstracts of the records recovered by the search, read through the full-text articles of potentially eligible studies, and extracted data. We a... We included 11 studies with a total of 2125 participants. One study was conducted in a laboratory setting and was not considered for drawing conclusions on intervention effects. The included studies i... Forward and faster rotation may reduce sleepiness during shifts, and may make no difference to sleep quality, but the evidence is very uncertain. Very low-certainty evidence indicated that sleep durat...

Sleep Duration and the Risk of Atherosclerosis: A Mendelian Randomization Study.

The association between the length of sleep and atherosclerosis has been reported in many observational studies. However, little is known about its significance as a risk factor for atherosclerosis or... This study aimed to assess the causal association between sleep duration and the risk of atherosclerosis using publicly available genome-wide association studies (GWAS) summary statistics.... We employed a two-sample Mendelian randomization (MR) method with 2 cohorts from MRC-IEU (n=460,099) and UK Biobank (n=361,194) to investigate the causal association between sleep duration and the ris... No causal association of sleep duration with atherosclerosis was found [OR (95%CI): 0.90 (0.98-1.00), p = 0.186]. Leave-one-out, MR-Egger, and MR-PRESSO analyses failed to detect horizontal pleiotropy... This MR analysis indicated no causal association between genetically predicted sleep duration and atherosclerosis across European populations....

Sleep duration, sleep quality and the risk of being obese: Evidence from the Australian panel survey.

Sleep difficulty is an unmet public health concern affecting a vast proportion of the world's population. Poor sleep duration (short or long sleep length) and quality affect more than half of older pe... We used three waves (waves 13, 17, and 21) of the nationally representative Household, Income and Labour Dynamics in Australia (HILDA) survey data. The study applied generalized estimating equations (... The study found that the odds of being obese was significantly higher amongst the study participants with poor sleep duration (adjusted odds ratio [aOR]: 1.24, 95% confidence interval [CI]: 1.16-1.32)... Having short or long sleep at night and poor sleep quality are associated with an increased risk of obesity. Obesity poses a significant threat to the health of Australian adults. Enacting policies th...

Short sleep duration and adolescent health: does weekend catch-up sleep work and for whom?

Despite evidence that sleep duration affects adolescent health, there remain important research gaps in the literature. Little is known about (1) whether the association between weekday sleep duration... Using six waves of longitudinal data from the 2011-2016 Korean Children and Youth Panel Survey (N = 6633), this study examined the relationship between weekday sleep duration, WCS duration, and two me... We estimated fixed effects models to account for individual-level heterogeneity.... Fixed effects estimates suggest that part of the associations between short sleep duration and adolescent health are confounded by unobserved individual heterogeneity (62% for BMI and 30% for poor SRH... Short weekday sleep duration threatens adolescent health. WCS duration is protective only for those who are most sleep deprived....

Associations of self-reported sleep duration and sleep quality during pregnancy with newborn telomere length.

Telomere length (TL) at birth is considered a potential biomarker for lifelong health. Although maternal sleep disturbance has been linked to a series of adverse pregnancy outcomes, evidence on the ef... A total of 742 mother-newborn pairs were recruited from Wuhan Children's Hospital between November 2013 and March 2015. Cord blood TL was measured using real-time quantitative polymerase chain reactio... A total of 742 maternal-newborn pairs were included in the analyses. Mothers sleeping ≥10 hours had a 9.30% (95% CI: 2.09%, 15.99%) shorter newborn TL than those sleeping 7-<9 hours. However, the asso... Long sleep duration and poor sleep quality during late pregnancy were associated with shorter newborn TL....

Baseline sleep characteristics are associated with gains in sleep duration after cognitive behavioral therapy for insomnia.

Cognitive behavioural therapy for insomnia (CBT-I) substantially reduces total wake time (TWT) by the end of treatment. In contrast, total sleep time (TST) does not increase above baseline levels for ... Data were analysed from a randomised controlled trial assessing acute and maintenance CBT-I (N = 80). Linear mixed models were conducted to assess the effect of baseline characteristics on changes in ... At baseline, self-reported sleep latency, wake after sleep onset, early morning awakenings, TWT, TST, and sleep efficiency were associated with the greatest changes in TST (p < .03 for interactions), ... Patients with more severe self-reported sleep difficulties and lower sleep duration at baseline showed greater improvements in TST after CBT-I. Whether more patients could increase their TST, within t...