questionsmedicales.fr
Systèmes sanguin et immunitaire
Système immunitaire
Leucocytes
Granulocytes
Granulocytes : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Granulocytes
Granulocytopénie
Numération formule sanguine
Granulocytes
Symptômes
5
Granulocytopénie
Infection
Réaction allergique
Granulocytes
Inflammation
Granulocytes
Infection bactérienne
Granulocytes
Prévention
5
Prévention des infections
Granulocytes
Complications
Granulocytes
Traitements
5
Granulocytopénie
Transfusion
Corticostéroïdes
Inflammation
Greffe de moelle osseuse
Granulocytes
Complications
5
Granulocytopénie
Infection
Leucémie myéloïde
Granulocytes
Cicatrisation
Granulocytes
Immunosuppresseurs
Granulocytes
Effets secondaires
Granulocytes
Facteurs de risque
5
Immunodépression
Infection
Maladies auto-immunes
Granulocytes
Produits chimiques
Granulocytes
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"position": 8,
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"position": 10,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Comment prévenir les infections chez les patients à faible granulocytes ?",
"position": 11,
"acceptedAnswer": {
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"text": "Maintenir une bonne hygiène et éviter les foules sont essentiels."
}
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{
"@type": "Question",
"name": "Quels vaccins sont recommandés ?",
"position": 12,
"acceptedAnswer": {
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"text": "Les vaccins contre la grippe et le pneumocoque sont souvent conseillés."
}
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{
"@type": "Question",
"name": "Comment éviter les complications liées aux granulocytes ?",
"position": 13,
"acceptedAnswer": {
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"text": "Surveiller les signes d'infection et consulter rapidement un médecin."
}
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{
"@type": "Question",
"name": "Quel rôle de l'alimentation dans la prévention ?",
"position": 14,
"acceptedAnswer": {
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"text": "Une alimentation équilibrée renforce le système immunitaire."
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{
"@type": "Question",
"name": "Comment gérer le stress pour la santé des granulocytes ?",
"position": 15,
"acceptedAnswer": {
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"text": "Des techniques de relaxation peuvent aider à réduire le stress."
}
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{
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"name": "Comment traiter une granulocytopénie ?",
"position": 16,
"acceptedAnswer": {
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"name": "Quels médicaments stimulent les granulocytes ?",
"position": 17,
"acceptedAnswer": {
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"text": "Le filgrastim et le pegfilgrastim sont des agents couramment utilisés."
}
},
{
"@type": "Question",
"name": "Comment traiter une infection liée aux granulocytes ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antibiotiques sont prescrits pour traiter les infections bactériennes."
}
},
{
"@type": "Question",
"name": "Quel rôle des corticostéroïdes dans le traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent réduire l'inflammation et moduler la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Quand envisager une greffe de moelle osseuse ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "En cas de maladies graves affectant la production de granulocytes."
}
},
{
"@type": "Question",
"name": "Quelles complications d'une granulocytopénie sévère ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections graves, septicémie et complications hémorragiques peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quels risques d'une leucémie myéloïde ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Risque accru d'infections et de saignements en raison de la production anormale."
}
},
{
"@type": "Question",
"name": "Comment les granulocytes affectent-ils la cicatrisation ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une diminution des granulocytes peut retarder la cicatrisation des plaies."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications des traitements immunosuppresseurs ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections opportunistes et cancers peuvent survenir avec ces traitements."
}
},
{
"@type": "Question",
"name": "Quels effets secondaires des médicaments sur les granulocytes ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments peuvent entraîner une diminution des granulocytes."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'infections ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une immunodépression, le diabète et l'âge avancé augmentent le risque."
}
},
{
"@type": "Question",
"name": "Quel rôle des maladies auto-immunes ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner une destruction accrue des granulocytes."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme affecte-t-il les granulocytes ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme peut altérer la fonction des granulocytes et augmenter l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels risques liés à l'exposition aux produits chimiques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains produits chimiques peuvent endommager la moelle osseuse et réduire les granulocytes."
}
},
{
"@type": "Question",
"name": "Quel impact de la génétique sur les granulocytes ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des prédispositions génétiques peuvent influencer la production et la fonction des granulocytes."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 17/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Department of Anesthesiology, University Hospital Regensburg, Raubling, Germany.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Institute of Pharmacology, University of Bern, Bern, Switzerland; email: thomas.kaufmann@pki.unibe.ch, hans-uwe.simon@pki.unibe.ch.
Department of Clinical Immunology and Allergology, Sechenov University, Moscow, Russia.
Laboratory of Molecular Immunology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Brandenburg Medical School, Neuruppin, Germany.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China.
Publications dans "Granulocytes" :
2 publications dans cette catégorie
Affiliations :
Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China; Beijing Key Laboratory for Therapeutic Cancer Vaccines, Beijing 100038, China. Electronic address: zhangju@mail.ccmu.edu.cn.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Immunology, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Laboratory Medicine, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Krakow, Poland.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Immunology, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Cayuga Medical Center, 101 Dates Drive, Ithaca, NY 14850, USA; Weill Cornell Medicine. Electronic address: dmac92077@gmail.com.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Cayuga Medical Center, 101 Dates Drive, Ithaca, NY 14850, USA.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Studies, University of Pennsylvania, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Comparative Pathobiology, Tufts University, Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA.
Publications dans "Granulocytes" :
1 publication dans cette catégorie
Affiliations :
Department of Clinical Studies, University of Pennsylvania, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA. Electronic address: rnolenw@upenn.edu.
Publications dans "Granulocytes" :
Granulocyte transfusions continue to be used in clinical practice, predominantly for treatment of refractory infection in the setting of severe neutropenia. There is biological plausibility for effect...
The blood bank is often consulted for transfusion support of patients with suspected platelet transfusion refractoriness (PTR). The workup is complex because testing includes specialized assays that a...
To provide pathologists who may not have subspecialized training in transfusion medicine and who direct blood banks algorithmic workflows based on clinical scenario and test availability to provide ap...
This review is a comprehensive overview of terminology, HLA testing procedures, interpretations, and practical recommendations for managing PTR in various scenarios based on expert opinion as well as ...
Consultation on PTR is complicated and encompasses many clinical and laboratory aspects. The lack of guidelines derived from high-quality prospective studies poses challenges in the workup and managem...
The removal of leukocytes from blood components helps to prevent or reduce some adverse reactions that occur after blood transfusions. The implementation of the leukodepletion process in the preparati...
The aim of this retrospective study was to determine whether there is an association between leukoreduction of packed red blood cell (pRBC) units and reduction of clinically observed transfusion react...
Medical data on dogs transfused with leukocyte-reduced (LR) and non-leukocyte-reduced (N-LR) pRBC units at the Animal Hospital Zürich, University of Zürich, Switzerland between January 1, 2007, and De...
A total of 339 canine patients were transfused with 413 pRBC units; 30.5% (126/413) were LR units and 69.5% (287/413) were N-LR. Data collected from medical records was analyzed using univariate and m...
In the present study, the leukocyte-depletion of transfused pRBC units was not associated with fewer TR nor to fewer FNHTR compared to N-LR units. Discharge of dogs from hospital was not dependent on ...
The development of new human leukocyte antigens (HLAs) and donor-specific antibodies (DSAs) in patients are associated with worse outcomes following lung transplantation. The authors aimed to examine ...
A retrospective observational study....
At a single academic tertiary center....
Adult lung transplant recipients who underwent transplantation between September 2014 and June 2019....
None....
A total of 380 patients were included in this study, and 87 (23%) developed de novo donor-specific antibodies in the first year after transplantation. Eighty-five patients (22%) developed new HLA anti...
Increased perioperative transfusion of platelets and cryoprecipitate are associated with de novo HLA and DSA development, respectively, in lung transplant recipients during the first year after transp...
Although it remains controversial, premedication before transfusion is a common clinical practice to prevent transfusion-associated adverse reactions (TAARs) in Taiwan. Thus, we aimed to investigate w...
Clinical data from outpatients receiving transfusion therapy, including predisposing diseases, histories of transfusion and TAARs, premedication and the occurrence of TAARs in the period April 2017 to...
A total of 5018 blood units were transfused to 803 outpatients, with 2493 transfusion events reported in the study interval. The most frequently transfused component was leukocyte-reduced packed red c...
Decreased premedication was not associated with increased incidence of TAARs in outpatients; these findings provide important evidence to support the need to revise clinical practices in the era of le...
Beta-thalassemia major patients need a regular blood transfusion to have an initial normal growth. However, these patients have an increased risk of developing alloantibodies. Our main goal was to stu...
The study consisted of 53 Moroccan pediatric patients with Beta-thalassemia major. Screening for HLA alloantibodies was performed using Luminex technology Whereas HLA genotyping was done with sequence...
In this study, 50.9% of patients have been identified as positive for HLA antibodies, with 59.3% having both HLA Class I and Class II antibodies. A significant increase frequency of DRB1*11 allele was...
This paper revealed that the transfusion dependent Beta-thalassemia major patients are exposed to risk of developing HLA antibodies following transfusions with leukoreduced RBC units. The HLA DRB1*11 ...
Background Packed red blood cell (PRBC) transfusions are routine in neonatal care and the most common blood product administered to sick neonates. However, their impact on leukocyte and platelet profi...
Monocyte-to-M0/M1 macrophage differentiation with unclear molecular mechanisms is a pivotal cellular event in many cardiovascular diseases including atherosclerosis. Long non-coding RNAs (lncRNAs) are...
Using a previously characterized and described abdominal model to define the avian immune response to...