Titre : Granulocytes

Granulocytes : Questions médicales fréquentes

Termes MeSH sélectionnés :

REM Sleep Behavior Disorder
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granulocytes ?\nQuel rôle joue la biopsie dans le diagnostic ?", "url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=REM+Sleep+Behavior+Disorder&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Granulocytes", "description": "Quels symptômes d'une carence en granulocytes ?\nComment se manifeste une réaction allergique ?\nQuels symptômes d'une inflammation ?\nQuels signes d'une infection bactérienne ?\nQuels symptômes d'une leucémie ?", "url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=REM+Sleep+Behavior+Disorder&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Granulocytes", "description": "Comment prévenir les infections chez les patients à faible granulocytes ?\nQuels vaccins sont recommandés ?\nComment éviter les complications liées aux granulocytes ?\nQuel rôle de l'alimentation dans la prévention ?\nComment gérer le stress pour la santé des granulocytes ?", "url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=REM+Sleep+Behavior+Disorder&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Granulocytes", "description": "Comment traiter une granulocytopénie ?\nQuels médicaments stimulent les granulocytes ?\nComment traiter une infection liée aux granulocytes ?\nQuel rôle des corticostéroïdes dans le traitement ?\nQuand envisager une greffe de moelle osseuse ?", "url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=REM+Sleep+Behavior+Disorder&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Granulocytes", "description": "Quelles complications d'une granulocytopénie sévère ?\nQuels risques d'une leucémie myéloïde ?\nComment les granulocytes affectent-ils la cicatrisation ?\nQuelles sont les complications des traitements immunosuppresseurs ?\nQuels effets secondaires des médicaments sur les granulocytes ?", "url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=REM+Sleep+Behavior+Disorder&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Granulocytes", "description": "Quels facteurs augmentent le risque d'infections ?\nQuel rôle des maladies auto-immunes ?\nComment le tabagisme affecte-t-il les granulocytes ?\nQuels risques liés à l'exposition aux produits chimiques ?\nQuel impact de la génétique sur les granulocytes ?", "url": "https://questionsmedicales.fr/mesh/D006098?mesh_terms=REM+Sleep+Behavior+Disorder&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une granulocytopénie ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Un hémogramme révèle une diminution des granulocytes dans le sang." } }, { "@type": "Question", "name": "Quels tests pour évaluer les granulocytes ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests sanguins comme la numération formule sanguine sont utilisés." } }, { "@type": "Question", "name": "Quels signes indiquent une infection liée aux granulocytes ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Fièvre, fatigue et inflammation peuvent signaler une infection." } }, { "@type": "Question", "name": "Comment évaluer la fonction des granulocytes ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de phagocytose et de dégranulation peuvent être réalisés." } }, { "@type": "Question", "name": "Quel rôle joue la biopsie dans le diagnostic ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Une biopsie médullaire peut aider à évaluer la production de granulocytes." } }, { "@type": "Question", "name": "Quels symptômes d'une carence en granulocytes ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Infections fréquentes, fièvre et fatigue sont des symptômes courants." } }, { "@type": "Question", "name": "Comment se manifeste une réaction allergique ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Éruptions cutanées, démangeaisons et œdème peuvent survenir." } }, { "@type": "Question", "name": "Quels symptômes d'une inflammation ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Rougeur, chaleur, gonflement et douleur sont des signes d'inflammation." } }, { "@type": "Question", "name": "Quels signes d'une infection bactérienne ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Fièvre, frissons et douleur localisée peuvent indiquer une infection." } }, { "@type": "Question", "name": "Quels symptômes d'une leucémie ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Fatigue, ecchymoses et infections fréquentes peuvent être présents." } }, { "@type": "Question", "name": "Comment prévenir les infections chez les patients à faible granulocytes ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Maintenir une bonne hygiène et éviter les foules sont essentiels." } }, { "@type": "Question", "name": "Quels vaccins sont recommandés ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Les vaccins contre la grippe et le pneumocoque sont souvent conseillés." } }, { "@type": "Question", "name": "Comment éviter les complications liées aux granulocytes ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Surveiller les signes d'infection et consulter rapidement un médecin." } }, { "@type": "Question", "name": "Quel rôle de l'alimentation dans la prévention ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée renforce le système immunitaire." } }, { "@type": "Question", "name": "Comment gérer le stress pour la santé des granulocytes ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Des techniques de relaxation peuvent aider à réduire le stress." } }, { "@type": "Question", "name": "Comment traiter une granulocytopénie ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Des transfusions de granulocytes ou des médicaments stimulants peuvent être utilisés." } }, { "@type": "Question", "name": "Quels médicaments stimulent les granulocytes ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Le filgrastim et le pegfilgrastim sont des agents couramment utilisés." } }, { "@type": "Question", "name": "Comment traiter une infection liée aux granulocytes ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des antibiotiques sont prescrits pour traiter les infections bactériennes." } }, { "@type": "Question", "name": "Quel rôle des corticostéroïdes dans le traitement ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent réduire l'inflammation et moduler la réponse immunitaire." } }, { "@type": "Question", "name": "Quand envisager une greffe de moelle osseuse ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "En cas de maladies graves affectant la production de granulocytes." } }, { "@type": "Question", "name": "Quelles complications d'une granulocytopénie sévère ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Infections graves, septicémie et complications hémorragiques peuvent survenir." } }, { "@type": "Question", "name": "Quels risques d'une leucémie myéloïde ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Risque accru d'infections et de saignements en raison de la production anormale." } }, { "@type": "Question", "name": "Comment les granulocytes affectent-ils la cicatrisation ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Une diminution des granulocytes peut retarder la cicatrisation des plaies." } }, { "@type": "Question", "name": "Quelles sont les complications des traitements immunosuppresseurs ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Infections opportunistes et cancers peuvent survenir avec ces traitements." } }, { "@type": "Question", "name": "Quels effets secondaires des médicaments sur les granulocytes ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Certains médicaments peuvent entraîner une diminution des granulocytes." } }, { "@type": "Question", "name": "Quels facteurs augmentent le risque d'infections ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Une immunodépression, le diabète et l'âge avancé augmentent le risque." } }, { "@type": "Question", "name": "Quel rôle des maladies auto-immunes ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent entraîner une destruction accrue des granulocytes." } }, { "@type": "Question", "name": "Comment le tabagisme affecte-t-il les granulocytes ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Le tabagisme peut altérer la fonction des granulocytes et augmenter l'inflammation." } }, { "@type": "Question", "name": "Quels risques liés à l'exposition aux produits chimiques ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certains produits chimiques peuvent endommager la moelle osseuse et réduire les granulocytes." } }, { "@type": "Question", "name": "Quel impact de la génétique sur les granulocytes ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Des prédispositions génétiques peuvent influencer la production et la fonction des granulocytes." } } ] } ] }

Sources (10000 au total)

REM Behavior Disorder: Implications for PD Therapeutics.

Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that occurs during REM sleep, characterized by REM sleep without atonia (RSWA) and dream enactment behavior (DEB). RBD is associa... Recent research recognizes RBD as a prodromal marker of PD, resulting in expansion of basic science and clinical investigations of RBD. Current basic science research investigates the pathophysiology ...

Neurofilament light chain and cardiac MIBG uptake as predictors for phenoconversion in isolated REM sleep behavior disorder.

Isolated rapid-eye-movement (REM) sleep behavior disorder (iRBD) is considered as a prodromal stage of either multiple system atrophy (MSA) or Lewy body disease (LBD; Parkinson's disease and dementia ... Forty patients with iRBD were enrolled between April 2018 and October 2019 and prospectively followed every 3 months to determine phenoconversion to either MSA or LBD. Plasma NfL levels were measured ... Patients were followed for a median of 2.92 years. Four patients converted to MSA and 7 to LBD. Plasma NfL level at baseline was significantly higher in future MSA-converters (median 23.2 pg/mL) when ... Plasma NfL and cardiac MIBG uptake may be useful biomarkers in predicting phenoconversion of iRBD. Elevated plasma NfL levels may suggest imminent phenoconversion to MSA, whereas low cardiac MIBG upta...

Cerebellar Volume Reduction in Patients with Isolated REM Sleep Behavior Disorder: Evidence of a Potential Role of the Cerebellum.

In this study, we aimed to investigate changes in the total cerebellar volume, subdivisions of the cerebellar volume, and intrinsic cerebellar network in patients with isolated rapid eye movement (REM... We enrolled patients with newly diagnosed iRBD and healthy controls who had no structural lesions according to their brain MRI. All participants underwent three-dimensional T1-weighted imaging. We obt... In total, we enrolled 43 patients with iRBD and 47 healthy controls. Total cerebellar volume in patients with iRBD was lower than that in the healthy controls (8.4637 vs. 9.0863%, p = 0.0001). There w... We found decreased total cerebellar volumes and subdivisions of the cerebellar volume, particularly in the right and left lobule VIIB, in patients with iRBD compared to healthy controls. The present r...

Cognitive and motor profiles as prodromal markers in predicting phenoconversion and phenotype in isolated REM sleep behavior disorder.

To determine the clinical markers based on cognitive and motor profiles in predicting phenoconverion and phenotype in isolated rapid eye movement sleep behavior disorder (iRBD).... 45 iRBD patients and 25 healthy controls were included in the follow-up study. All participates received comprehensive evaluations of cognitive, motor and autonomic function at baseline. Positive phen... 21 iRBD patients displayed phenoconversion in a mean follow-up of 2.9 ± 1.6 years, with 14 presenting motor phenotype and 7 cognitive phenotype. In iRBD, visuospatial, memory, attention-executive func... In iRBD, the attention-executive and motor function served as optimum combined markers in predicting phenoconversion and motor phenotype, whereas the attention-executive function performed best in pre...

Misfolded α-Synuclein Assessment in the Skin and CSF by RT-QuIC in Isolated REM Sleep Behavior Disorder.

Real-time quaking-induced conversion (RT-QuIC) assay detects misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies Parkinson disease and dementia with Lewy bodies. Isol... This was a cross-sectional study where consecutive patients with polysomnographic-confirmed IRBD and age-matched controls without RBD underwent skin biopsy and lumbar puncture the same day. Three-mill... We recruited 91 patients with IRBD and 41 controls. In the skin, sensitivity to detect AS was 76.9% (95% CI 66.9-85.1), specificity 97.6% (95% CI 87.1-99.9) positive predictive value 98.6% (95% CI 91.... Our study in IRBD shows that (1) RT-QuIC detects AS in the skin and CSF with similar high sensitivity, specificity, and agreement, (2) AS RT-QuIC positivity is associated with supportive features and ... This study provides Class III evidence that RT-QuIC-detected AS in the skin and CSF distinguishes patients with IRBD from controls....

Tonic REM sleep muscle activity is the strongest predictor of phenoconversion risk to neurodegenerative disease in isolated REM sleep behaviour disorder.

Previous studies have shown that rapid eye movement sleep without atonia during polysomnography can predict the risk of phenoconversion to neurodegenerative disease in patients with isolated rapid eye...

REM Sleep Behavior Disorder and Its Possible Prodromes in General Population: Prevalence, Polysomnography Findings, and Associated Factors.

To evaluate the prevalence of REM sleep behavior disorder (RBD) and its possible prodromal conditions, isolated dream enactment behavior (DEB) and isolated REM without atonia (RWA), in a general popul... From a population-based prospective cohort in Korea, 1,075 participants (age 60.1 ± 7.0 years; range 50-80 years; men 53.7%) completed the RBD screening questionnaire (RBDSQ), a structured telephone i... RBD was diagnosed in 20 participants, isolated RWA in 133 participants, and isolated DEB in 48 participants. Sex and DEB frequency-adjusted prevalence of RBD was 1.4% (95% CI 1.0%-1.8%), isolated RWA ... This study provides prevalence estimates of RBD and its possible prodromal conditions based on a structured telephone interview and RWA measurement on PSG from the general population....