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Systèmes sanguin et immunitaire
Système immunitaire
Leucocytes
Granulocytes
Granulocytes : Questions médicales fréquentes
Termes MeSH sélectionnés :
REM Sleep Behavior Disorder
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"name": "Comment diagnostiquer une granulocytopénie ?",
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"text": "Un hémogramme révèle une diminution des granulocytes dans le sang."
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"name": "Quels tests pour évaluer les granulocytes ?",
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"@type": "Question",
"name": "Quels signes indiquent une infection liée aux granulocytes ?",
"position": 3,
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"@type": "Answer",
"text": "Fièvre, fatigue et inflammation peuvent signaler une infection."
}
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{
"@type": "Question",
"name": "Comment évaluer la fonction des granulocytes ?",
"position": 4,
"acceptedAnswer": {
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"text": "Des tests de phagocytose et de dégranulation peuvent être réalisés."
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"@type": "Question",
"name": "Quel rôle joue la biopsie dans le diagnostic ?",
"position": 5,
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"name": "Quels symptômes d'une carence en granulocytes ?",
"position": 6,
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"name": "Comment se manifeste une réaction allergique ?",
"position": 7,
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"name": "Quels symptômes d'une inflammation ?",
"position": 8,
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"text": "Rougeur, chaleur, gonflement et douleur sont des signes d'inflammation."
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"name": "Quels signes d'une infection bactérienne ?",
"position": 9,
"acceptedAnswer": {
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"text": "Fièvre, frissons et douleur localisée peuvent indiquer une infection."
}
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"name": "Quels symptômes d'une leucémie ?",
"position": 10,
"acceptedAnswer": {
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"text": "Fatigue, ecchymoses et infections fréquentes peuvent être présents."
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{
"@type": "Question",
"name": "Comment prévenir les infections chez les patients à faible granulocytes ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une bonne hygiène et éviter les foules sont essentiels."
}
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{
"@type": "Question",
"name": "Quels vaccins sont recommandés ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les vaccins contre la grippe et le pneumocoque sont souvent conseillés."
}
},
{
"@type": "Question",
"name": "Comment éviter les complications liées aux granulocytes ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Surveiller les signes d'infection et consulter rapidement un médecin."
}
},
{
"@type": "Question",
"name": "Quel rôle de l'alimentation dans la prévention ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée renforce le système immunitaire."
}
},
{
"@type": "Question",
"name": "Comment gérer le stress pour la santé des granulocytes ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques de relaxation peuvent aider à réduire le stress."
}
},
{
"@type": "Question",
"name": "Comment traiter une granulocytopénie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des transfusions de granulocytes ou des médicaments stimulants peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Quels médicaments stimulent les granulocytes ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le filgrastim et le pegfilgrastim sont des agents couramment utilisés."
}
},
{
"@type": "Question",
"name": "Comment traiter une infection liée aux granulocytes ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antibiotiques sont prescrits pour traiter les infections bactériennes."
}
},
{
"@type": "Question",
"name": "Quel rôle des corticostéroïdes dans le traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent réduire l'inflammation et moduler la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Quand envisager une greffe de moelle osseuse ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "En cas de maladies graves affectant la production de granulocytes."
}
},
{
"@type": "Question",
"name": "Quelles complications d'une granulocytopénie sévère ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections graves, septicémie et complications hémorragiques peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quels risques d'une leucémie myéloïde ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Risque accru d'infections et de saignements en raison de la production anormale."
}
},
{
"@type": "Question",
"name": "Comment les granulocytes affectent-ils la cicatrisation ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une diminution des granulocytes peut retarder la cicatrisation des plaies."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications des traitements immunosuppresseurs ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections opportunistes et cancers peuvent survenir avec ces traitements."
}
},
{
"@type": "Question",
"name": "Quels effets secondaires des médicaments sur les granulocytes ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments peuvent entraîner une diminution des granulocytes."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'infections ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une immunodépression, le diabète et l'âge avancé augmentent le risque."
}
},
{
"@type": "Question",
"name": "Quel rôle des maladies auto-immunes ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner une destruction accrue des granulocytes."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme affecte-t-il les granulocytes ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme peut altérer la fonction des granulocytes et augmenter l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels risques liés à l'exposition aux produits chimiques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains produits chimiques peuvent endommager la moelle osseuse et réduire les granulocytes."
}
},
{
"@type": "Question",
"name": "Quel impact de la génétique sur les granulocytes ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des prédispositions génétiques peuvent influencer la production et la fonction des granulocytes."
}
}
]
}
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The objective of this study was to assess the role of cognitive evaluation in the prediction of phenoconversion in polysomnography-confirmed idiopathic or isolated rapid eye movement sleep behaviour d...
REM sleep behaviour disorder (RBD) is common in narcolepsy type 1 (NT1). Abnormalities in the reward system have been observed in NT1, possibly related to impaired orexin projections towards the mesol...
Isolated rapid eye movement sleep behavior disorder (iRBD) is a sleep disorder characterized by dream enactment behavior without any neurological disease and is frequently accompanied by cognitive dys...
We applied a combination of SSM/PCA and GMLVQ as a classifier on FDG-PET data of healthy controls, AD, DLB, and PD patients. We determined the diagnostic performance by performing a ten times repeated...
The GMLVQ prototypes, relevance diagonal, and decision space voxel maps showed metabolic patterns that agree with previously identified disease-related brain patterns. The GMLVQ decision space showed ...
In this proof-of-concept study, we show that GMLVQ provides a classification of patients with neurodegenerative disorders, and may be useful in future studies investigating speed of progression in pro...
Studies have shown that rapid eye movement (REM) sleep behavior disorder (RBD) is a subtype of Parkinson's disease (PD) characterized by severe cognitive impairment and rapid disease progression. Howe...
The isolated rapid-eye-movement sleep behavior disorder (iRBD) is a prodromal condition of Lewy body disease including Parkinson's disease and dementia with Lewy bodies (DLB). We aim to investigate th...
We enrolled 22 DLB patients, 44 healthy controls, and 50 video polysomnography-proven iRBD patients. Participants underwent 3-T magnetic resonance imaging (MRI) and clinical/neuropsychological evaluat...
The DLB-pattern was characterized by thinning of the temporal, orbitofrontal, and insular cortices and relative preservation of the precentral and inferior parietal cortices. The DLB-pattern expressio...
Cortical thickness signature can effectively reflect the longitudinal evolution of Lewy body dementia in the iRBD population. Replication studies would further validate the utility of this imaging mar...
Isolated REM sleep behaviour disorder (iRBD) is characterised by dream enactment behaviours, such as kicking and punching while asleep, and vivid/violent dreams. It is now acknowledged as a prodromal ...
Nearly 80% of people diagnosed with idiopathic REM sleep behaviour disorder (iRBD) via video-polysomnography (v-PSG) are expected to be in the prodromal stage of an alpha-synucleinopathy. Signs of aut...
The aim of this study was to evaluate dysautonomia in iRBD subjects using HRV obtained during different sleep stages and wakefulness from v-PSG....
Subjects positively screened by an RBD screening questionnaire (RBD-SQ) underwent v-PSG to diagnose RBD. HRV obtained from v-PSG recordings was correlated to dysautonomia evaluated from a Non-Motor Sy...
Out of 72 positively screened subjects, 29 subjects were diagnosed as iRBD (mean age 66 ± 7.7 years) by v-PSG. Eighty-three per cent of the iRBD subjects in our cohort were at the time of diagnosis cl...
The presented study did not confirm the possibility of using HRV from v-PSG records of patients with iRBD to predict dysautonomia expressed by questionnaire methods. This is probably due to several co...
Isolated REM sleep behaviour disorder (iRBD) patients are at high risk of developing clinical syndromes of the α-synuclein spectrum. Progression markers are needed to determine the neurodegenerative c...
Twenty iRBD patients underwent two consecutive...
Individual hypometabolism t-maps revealed three scenarios: (1) normal...
Our results suggest that occipital hypometabolism at baseline in iRBD implies a short-term conversion to PD. This might help in stratification strategies for disease-modifying trials....
Isolated REM sleep behavior disorder (iRBD) is an early α-synucleinopathy often accompanied by incipient cognitive impairment. As executive dysfunctions predict earlier phenotypic conversion from iRBD...
The study CogTrAiL-RBD investigates the short- and long-term effectiveness and the feasibility and underlying neural mechanisms of a cognitive training intervention for individuals with iRBD. The inte...
This study will provide insights into whether cognitive training and psychoeducation on a healthy, active lifestyle have short- and long-term (neuro-)protective effects for individuals with iRBD....
The study was prospectively registered in the German Clinical Trial Register (DRKS00024898) on 2022-03-11, https://drks.de/search/de/trial/DRKS00024898 ....
V5 2023-04-24....