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Facteurs biologiques
Antigènes
Épitopes
Haptènes
Haptènes : Questions médicales fréquentes
Termes MeSH sélectionnés :
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"description": "Comment diagnostiquer une allergie aux haptènes ?\nQuels tests sont utilisés pour les haptènes ?\nLes haptènes peuvent-ils être détectés dans le sang ?\nQuels symptômes indiquent une réaction aux haptènes ?\nLes haptènes sont-ils liés à des maladies auto-immunes ?",
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"name": "Comment diagnostiquer une allergie aux haptènes ?",
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"text": "Un test cutané ou un dosage des IgE spécifiques peut aider à diagnostiquer."
}
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour les haptènes ?",
"position": 2,
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"text": "Les tests d'allergie, comme les prick tests, sont couramment utilisés."
}
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"@type": "Question",
"name": "Les haptènes peuvent-ils être détectés dans le sang ?",
"position": 3,
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{
"@type": "Question",
"name": "Quels symptômes indiquent une réaction aux haptènes ?",
"position": 4,
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{
"@type": "Question",
"name": "Quels sont les symptômes d'une allergie aux haptènes ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les symptômes incluent démangeaisons, éruptions cutanées et œdème."
}
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{
"@type": "Question",
"name": "Les haptènes provoquent-ils des symptômes respiratoires ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent provoquer des symptômes comme l'asthme ou la rhinite."
}
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{
"@type": "Question",
"name": "Les haptènes peuvent-ils causer des réactions sévères ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des réactions anaphylactiques peuvent survenir dans certains cas."
}
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{
"@type": "Question",
"name": "Comment se manifestent les éruptions cutanées dues aux haptènes ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles apparaissent souvent sous forme de rougeurs, démangeaisons et cloques."
}
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{
"@type": "Question",
"name": "Les haptènes peuvent-ils affecter le système digestif ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent provoquer des symptômes gastro-intestinaux comme des nausées."
}
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{
"@type": "Question",
"name": "Comment prévenir les allergies aux haptènes ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évitez les substances connues et lisez les étiquettes des produits."
}
},
{
"@type": "Question",
"name": "Les tests cutanés aident-ils à la prévention ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent identifier les haptènes responsables et aider à éviter l'exposition."
}
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{
"@type": "Question",
"name": "Les vaccinations préviennent-elles les allergies aux haptènes ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les vaccinations ne préviennent pas les allergies aux haptènes."
}
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{
"@type": "Question",
"name": "Les changements alimentaires aident-ils à prévenir les allergies ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un régime alimentaire équilibré peut réduire le risque d'allergies."
}
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"@type": "Question",
"name": "Les mesures d'hygiène préventives sont-elles efficaces ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, une bonne hygiène peut réduire l'exposition aux allergènes."
}
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{
"@type": "Question",
"name": "Quel est le traitement principal pour les allergies aux haptènes ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'évitement de l'haptène et l'utilisation d'antihistaminiques sont recommandés."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces contre les haptènes ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent réduire l'inflammation et les symptômes allergiques."
}
},
{
"@type": "Question",
"name": "Peut-on désensibiliser aux haptènes ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La désensibilisation est possible, mais elle doit être supervisée médicalement."
}
},
{
"@type": "Question",
"name": "Quels médicaments sont utilisés pour les réactions sévères ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'épinéphrine est souvent utilisée pour traiter les réactions anaphylactiques."
}
},
{
"@type": "Question",
"name": "Les traitements naturels aident-ils contre les haptènes ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines approches naturelles peuvent soulager, mais peu de preuves scientifiques existent."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec les haptènes ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme l'anaphylaxie ou des dermatites chroniques peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les haptènes peuvent-ils causer des infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des infections cutanées peuvent survenir suite à des éruptions allergiques."
}
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"@type": "Question",
"name": "Les haptènes peuvent-ils aggraver des maladies existantes ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent exacerber des conditions comme l'asthme ou l'eczéma."
}
},
{
"@type": "Question",
"name": "Les complications psychologiques sont-elles possibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'anxiété liée aux allergies peut entraîner des complications psychologiques."
}
},
{
"@type": "Question",
"name": "Les haptènes peuvent-ils affecter la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les allergies aux haptènes peuvent réduire significativement la qualité de vie."
}
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{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les allergies aux haptènes ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux d'allergies et l'exposition précoce à des allergènes augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque d'allergies aux haptènes ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les jeunes enfants sont souvent plus sensibles aux allergies aux haptènes."
}
},
{
"@type": "Question",
"name": "Les maladies chroniques augmentent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme l'asthme peuvent augmenter le risque d'allergies."
}
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"@type": "Question",
"name": "Le mode de vie influence-t-il les allergies aux haptènes ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie urbain avec pollution peut augmenter le risque d'allergies."
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"@type": "Question",
"name": "Les allergies alimentaires sont-elles un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les allergies alimentaires peuvent prédisposer à d'autres allergies, y compris aux haptènes."
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Osteoarthritis (OA) is marked by the progressive degradation of joint cartilage and subchondral bone. The precise molecular mechanisms driving meniscus deterioration in OA, especially at the single-ce...
We analyzed two datasets from the GEO database, GSE220243 and GSE98918, focusing on meniscus tissue sequencing data from OA and non-OA patients. The standard Seurat procedure was employed to process s...
After quality control, 34,763 cells from the OA patients and 34,145 cells from the healthy controls were analyzed. UMAP identified and SingleR annotated 14 cell clusters. The 10 largest cell clusters ...
This research highlights crucial genes in the OA meniscus and uncovers their differing regulatory patterns between chondrocytes and non-chondrocytes. These findings enhance our understanding of the mo...
(1) Purpose: Retrospective back-to-back comparisons were performed to evaluate the accuracy, effectiveness, and incremental yield of chromosome microarray analysis (CMA) and exome sequencing (ES) anal...
Down syndrome (DS) is the most common congenital cause of intellectual disability and also leads to numerous metabolic and structural problems. This study aims to explore the application value of chro...
The study recruited 1452 pregnant women with abnormal DS screening results including 493 with an enlarged nuchal translucency thickness (NT ≥ 2.5 mm) and 959 with an abnormal second-trimester maternal...
CMA identified 74/1452 abnormal results, which was more efficient than karyotyping (51/1452, P < 0.05.) CMA is equivalent to traditional karyotyping for identifying aneuploidies. Compared to karyotypi...
CMA and karyotyping have both advantages and disadvantages in prenatal diagnosis of pregnant women with abnormal DS screening results. However, there was not enough evidence to support routine CMA in ...
Though copy number variants (CNVs) have been suggested to play a significant role in inborn errors of immunity (IEI), the precise nature of this role remains largely unexplored. We sought to determine...
We performed exome sequencing (ES) and CMA for 332 unrelated pediatric probands referred for evaluation of IEI. The analysis included primary, secondary, and incidental findings....
Of the 332 probands, 134 (40.4%) received molecular diagnoses. Of these, 116/134 (86.6%) were diagnosed by ES alone. An additional 15/134 (11.2%) were diagnosed by CMA alone, including two likely...
Pairing ES and CMA can provide a comprehensive evaluation to clarify the complex factors that contribute to both immune and non-immune phenotypes. Such a combined approach to genetic testing helps unt...
The aim of this study was to investigate the contribution of chromosomal microarray analysis (CMA) and next-generation sequencing (NGS) to genetic diagnosis in fetuses with normal karyotype who underw...
The results of invasive genetic testing performed at a tertiary center between September 2020 and March 2022 were retrospectively analyzed. Indications for invasive tests were classified as fetal stru...
A total of 830 invasive tests were performed and aneuploidy was detected in 11.2% of the fetuses. CMA was performed in 465 fetuses with normal karyotype, and pCNVs were detected in 6.9%. pCNVs were de...
pCNVs can be significantly detected not only in fetuses with structural malformations, but also in invasive testing with other indications. NGS significantly contributes to genetic diagnosis in fetuse...
Chromosomal microarray analysis (CMA) may detect variants of uncertain clinical significance (VUS) and susceptibility loci (SL) with incomplete penetrance for neurodevelopmental disorders. This qualit...
Semi-structured interviews were conducted with women who received a VUS and/or SL from prenatal CMA in the last 2-4 years and were analyzed using Grounded Theory....
The vast majority of women recalled being stressed by the findings. All women sought further advice and information to be able to decide whether to continue or terminate their pregnancy. The three pre...
Although uncertain/probabilistic information commonly involves a psychological burden, it may also be perceived as valuable and actionable. Pre-test parental choice regarding the disclosure of such in...
Aneuploidies are the most common chromosomal abnormality and the main genetic cause of adverse pregnancy outcomes. Since numerous studies have focused on common trisomies, relatively little is known a...
A total of 90 RAAs were detected, of which 83 cases were mosaic trisomies and 7 were non-mosaic trisomies. Chromosomes 16, 22, and 9 were identified as the major chromosomes involving RAAs. The four p...
Variable phenotypes and outcomes were observed, which were highly heterogeneous in cases of prenatal RAAs. Thus, a cautious and comprehensive strategy should be implemented during prenatal counseling ...
Alzheimer's disease is a prevalent health problem with a heavy global burden. Definitely diagnosed by autopsy, the clear mechanism of Alzheimer's disease pathogenesis process needs to be illustrated. ...
We attempted to discover the role of microRNA in Alzheimer's disease by microarray bioinformatics analysis using autopsy sample data from the GEO database. Temporal cortex samples were included in thi...
After filtering out significantly differential expressed microRNAs and genes, enrichment analyses of both microRNAs and genes were conducted, respectively. Then, we constructed a transcription factor-...
Hsa-miR-365b-5p act as a key target in Alzheimer's disease. It regulates Alzheimer's disease pathogenesis process via neuroinflammation, Wnt and oxidative stress pathway which provides a potential tar...
Background: There are few studies on the detection rate by chromosomal microarray analysis (CMA) of the prenatal diagnosis of talipes equinovarus (TE) compared to conventional karyotyping. We aimed to...
(1) Objective: To evaluate the application of chromosomal microarray analysis (CMA) in fetuses with pulmonary atresia (PA) and to explore the risk factors for predicting chromosomal imbalances and adv...