INSERM UMR_S 999, Pulmonary Arterial Hypertension: Physiopathology and Therapeutic Innovation, Marie Lannelongue Hospital, Le Plessis-Robinson, France; Department of Respiratory Medicine, University Paris-Sud, Medical School, University Paris-Saclay, Hôpitaux de Paris, National Reference Center for Severe Pulmonary Hypertension, Bicêtre Hospital, Le Kremlin Bicêtre, France.
Publications dans "Maladie veno-occlusive hépatique" :
INSERM UMR_S 999, Pulmonary Arterial Hypertension: Physiopathology and Therapeutic Innovation, Marie Lannelongue Hospital, Le Plessis-Robinson, France; Department of Respiratory Medicine, University Paris-Sud, Medical School, University Paris-Saclay, Hôpitaux de Paris, National Reference Center for Severe Pulmonary Hypertension, Bicêtre Hospital, Le Kremlin Bicêtre, France. Electronic address: david.montani@aphp.fr.
Publications dans "Maladie veno-occlusive hépatique" :
INSERM UMR_S 999, Pulmonary Arterial Hypertension: Physiopathology and Therapeutic Innovation, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Publications dans "Maladie veno-occlusive hépatique" :
INSERM UMR_S 999, Pulmonary Arterial Hypertension: Physiopathology and Therapeutic Innovation, Marie Lannelongue Hospital, Le Plessis-Robinson, France; Department of Respiratory Medicine, University Paris-Sud, Medical School, University Paris-Saclay, Hôpitaux de Paris, National Reference Center for Severe Pulmonary Hypertension, Bicêtre Hospital, Le Kremlin Bicêtre, France.
Publications dans "Maladie veno-occlusive hépatique" :
Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Regensburg, Regensburg, Germany. Electronic address: selim.corbacioglu@ukr.de.
Publications dans "Maladie veno-occlusive hépatique" :
INSERM UMR_S 999, Pulmonary Arterial Hypertension: Physiopathology and Therapeutic Innovation, Marie Lannelongue Hospital, Le Plessis-Robinson, France; Department of Respiratory Medicine, University Paris-Sud, Medical School, University Paris-Saclay, Hôpitaux de Paris, National Reference Center for Severe Pulmonary Hypertension, Bicêtre Hospital, Le Kremlin Bicêtre, France.
Publications dans "Maladie veno-occlusive hépatique" :
Université Paris-Saclay-Faculté de Médecine, Le Kremlin-Bicêtre, France.
AP-HP, Centre de Référence de l'Hypertension Pulmonaire, Service de Pneumologie et Réanimation Respiratoire, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
UMRS 999, INSERM and Université Paris-Saclay, Laboratoire d'Excellence en Recherche sur le Médicament et l'Innovation Thérapeutique, and.
Publications dans "Maladie veno-occlusive hépatique" :
Université Paris-Saclay-Faculté de Médecine, Le Kremlin-Bicêtre, France.
AP-HP, Centre de Référence de l'Hypertension Pulmonaire, Service de Pneumologie et Réanimation Respiratoire, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
UMRS 999, INSERM and Université Paris-Saclay, Laboratoire d'Excellence en Recherche sur le Médicament et l'Innovation Thérapeutique, and.
Publications dans "Maladie veno-occlusive hépatique" :
Sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) detected in the liver has been considered a severe complication of hematopoietic stem cell transplantation (HSCT). SOS/VOD is character...
Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a well-recognized complication of allogeneic and autologous hematopoietic cell transplantation (HCT). The diagnosis and trea...
Veno-occlusive disease (VOD) is a serious complication of hematopoietic stem cell transplantation (HSCT) with a high incidence in pediatric patients. This study aimed to detect signs of hypofibrinolys...
In this prospective single-center study, thrombelastographic measurements (EX and TPA tests) were taken during HSCT to detect signs of impaired coagulation, clot formation, or hypofibrinolysis....
Of 51 patients undergoing allogeneic and autologous HSCT, five (9.8%) developed VOD and received defibrotide treatment. Thrombelastography measurements were also obtained from 55 healthy children as a...
These results suggest that HSCT patients exhibit reduced fibrinolytic capacities and patients diagnosed with VOD show signs of hypofibrinolysis. This prospective study shows that fibrinolysis can be a...
Hepatic veno-occlusive disease or sinusoidal obstruction syndrome is a potentially life-threatening complication of hematopoietic stem cell transplantation....
To assess the usefulness of point shear-wave elastography (pSWE) for the early diagnosis of sinusoidal obstruction syndrome (SOS) in children....
A retrospective study was carried out in 43 patients with suspected SOS assessed between March 2018 and November 2021. Diagnosis of SOS was confirmed in 28 patients based on the European Society for B...
Liver stiffness on initial suspicion was higher in patients diagnosed with SOS and these values increased compared to the pre-transplantation values. A cutoff value of 1.37 m/s was found for the diagn...
Point shear wave elastography of the liver is a promising technique for the early diagnosis of pediatric SOS....
Defibrotide is approved to treat severe veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) after haematopoietic cell transplantation in patients aged > 1 month in the European Union and ...
PubMed, Embase and Web of Science were searched through 30 November 2021 for defibrotide studies in VOD/SOS "prevention" or "prophylaxis," excluding phase I studies, case reports, studies with fewer t...
The search identified 733 records; 24 met inclusion criteria, of which 20 (N = 3005) evaluated intravenous defibrotide for VOD/SOS prophylaxis. Overall VOD/SOS incidence with intravenous defibrotide w...
This analysis suggests a low incidence of VOD/SOS following intravenous defibrotide prophylaxis, regardless of age group, and a lower relative risk for VOD/SOS with defibrotide prophylaxis vs controls...
Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially life-threatening complication of haematopoietic cell transplantation (HCT) conditioning. The DEFIFrance post-marketing...
Sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) is an established complication in patients undergoing allogeneic hemopoietic stem cell transplantation (HSCT). Defibrotide is an effect...
Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially life-threatening complication of hematopoietic cell transplantation (HCT). This study aimed to determine a blo...
Hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), is a potentially life-threatening complication of hematopoietic stem cell transplantation. Patients present w...
There is a lack of data on the safety and efficacy of peritoneal drain (PD) and chest tube (CT) in the management of effusions in stem cell transplant recipients with veno-occlusive disease (VOD). In ...