questionsmedicales.fr
États, signes et symptômes pathologiques
Processus pathologiques
Caractéristiques de la maladie
Maladie chronique
Hépatite chronique
Hépatite chronique : Questions médicales fréquentes
Termes MeSH sélectionnés :
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"@type": "Question",
"name": "Comment diagnostiquer l'hépatite chronique ?",
"position": 1,
"acceptedAnswer": {
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"text": "Le diagnostic repose sur des tests sanguins, des échographies et parfois une biopsie hépatique."
}
},
{
"@type": "Question",
"name": "Quels tests sanguins sont utilisés ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent les marqueurs viraux, les enzymes hépatiques et les tests de fonction hépatique."
}
},
{
"@type": "Question",
"name": "Qu'est-ce qu'une biopsie hépatique ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "C'est un prélèvement de tissu hépatique pour évaluer l'inflammation et les lésions."
}
},
{
"@type": "Question",
"name": "Quels sont les signes d'hépatite chronique ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes peuvent inclure fatigue, jaunisse, douleurs abdominales et démangeaisons."
}
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{
"@type": "Question",
"name": "L'échographie est-elle utile ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'échographie permet de visualiser des anomalies du foie et d'évaluer sa taille."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes courants ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent fatigue, jaunisse, douleurs abdominales et perte d'appétit."
}
},
{
"@type": "Question",
"name": "La jaunisse est-elle un symptôme ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la jaunisse se manifeste par une coloration jaune de la peau et des yeux."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes asymptomatiques ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines personnes peuvent être asymptomatiques malgré une hépatite chronique."
}
},
{
"@type": "Question",
"name": "Les démangeaisons sont-elles fréquentes ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les démangeaisons peuvent survenir en raison de l'accumulation de bile dans le sang."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes psychologiques ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'anxiété et la dépression peuvent être des symptômes associés à l'hépatite chronique."
}
},
{
"@type": "Question",
"name": "Comment prévenir l'hépatite chronique ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La vaccination, l'hygiène et l'évitement des comportements à risque sont essentiels."
}
},
{
"@type": "Question",
"name": "La vaccination est-elle efficace ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la vaccination contre l'hépatite A et B est très efficace pour prévenir ces infections."
}
},
{
"@type": "Question",
"name": "Quels comportements à risque éviter ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évitez le partage d'aiguilles, les rapports sexuels non protégés et l'usage de drogues."
}
},
{
"@type": "Question",
"name": "L'hygiène joue-t-elle un rôle ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une bonne hygiène personnelle et alimentaire peut réduire le risque d'infection."
}
},
{
"@type": "Question",
"name": "Les tests de dépistage sont-ils importants ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage régulier est crucial pour détecter l'hépatite chronique tôt."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour l'hépatite chronique ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des antiviraux, des immunomodulateurs et des soins de soutien."
}
},
{
"@type": "Question",
"name": "Les antiviraux sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les antiviraux peuvent réduire la charge virale et améliorer la fonction hépatique."
}
},
{
"@type": "Question",
"name": "Quand faut-il envisager une transplantation ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La transplantation est envisagée en cas d'insuffisance hépatique sévère ou de complications graves."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements naturels ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains traitements naturels peuvent aider, mais ils doivent être discutés avec un médecin."
}
},
{
"@type": "Question",
"name": "Comment surveiller l'évolution de la maladie ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des suivis réguliers avec des tests sanguins et des échographies sont nécessaires."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la cirrhose, le cancer du foie et l'insuffisance hépatique."
}
},
{
"@type": "Question",
"name": "La cirrhose est-elle réversible ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, la cirrhose est une condition irréversible, mais son évolution peut être ralentie."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une insuffisance hépatique ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes incluent confusion, saignements, jaunisse et accumulation de liquide abdominal."
}
},
{
"@type": "Question",
"name": "Le cancer du foie est-il fréquent ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le cancer du foie peut survenir chez les patients atteints d'hépatite chronique."
}
},
{
"@type": "Question",
"name": "Comment prévenir les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi médical régulier et un traitement approprié peuvent aider à prévenir les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'infection virale, l'alcoolisme, et certaines maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "L'usage de drogues augmente-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'usage de drogues injectables augmente le risque d'hépatite chronique."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux d'hépatite peuvent augmenter le risque de développer la maladie."
}
},
{
"@type": "Question",
"name": "Le sexe influence-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains groupes de sexe peuvent avoir un risque plus élevé d'infection virale."
}
},
{
"@type": "Question",
"name": "Les voyages à l'étranger sont-ils un risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, voyager dans des régions à forte prévalence d'hépatite peut augmenter le risque d'infection."
}
}
]
}
]
}
Invasive prenatal evaluation by chromosomal microarray analysis (CMA) and karyotyping might represent an important option in pregnant women, but limited reports have applied CMA and karyotyping of fet...
This retrospective study included all singleton fetuses conceived by ART from January 2015 to December 2021. Anomalies prenatally diagnosed based on karyotyping and CMA were analyzed. Prevalence rates...
In total, 224 subjects were assessed by karyotyping and CMA. In the examined patients, chromosomal and karyotype abnormality rates were 3.57% (8/224) and 8.93% (20/224), respectively. This finding ind...
Prenatal diagnosis including karyotyping and CMA is recommended for fetuses conceived by ART, with or without ultrasound findings....
Karyotype analysis and fluorescence in situ hybridization (FISH) are commonly used for prenatal diagnosis, however they have many disadvantages. Chromosome microarray analysis (CMA) has the potential ...
A total of 3336 samples of amniotic fluid or umbilical cord blood from pregnant women with high-risk indicators at our center in southwest of China from June 2018 to January 2023 were included in the ...
3336 samples divided into 2911 cases with single and 425 cases with multiple high-risk indicators. The aneuploidy and pathogenic/likely pathogenic copy number variations (CNVs) of 2911 cases with sing...
The combined application of CMA and karyotyping were recommended in prenatal diagnosis for providing a scientific and accurate genetic diagnosis and improving the quality of prenatal genetic counselin...
Chromosomal microarray analysis (CMA) is typically performed for investigation of autism using blood DNA. However, blood collection poses significant challenges for autistic children with repetitive b...
The aim of this study was to investigate the incidence of chromosome anomalies in different types of congenital gastrointestinal obstruction and assess pregnancy outcomes of fetuses with congenital ga...
A total of 64 cases with gastrointestinal obstruction between January 2014 and December 2020 were enrolled in this study. They were divided into three groups according to sonographic images. Group A: ...
From January 2014 to December 2020, there were 64 fetus with congenital gastrointestinal obstruction underwent chromosome microarray analysis(CMA), the overall detection rate of CMA testing was 14.1%(...
It is crucial to understand whether the gastrointestinal tract abnormality is isolated or associated to other findings. The risk of chromosomal abnormalities in fetuses with isolated lower gastrointes...
To investigate the genetic burden in fetuses with isolated and severe fetal growth restriction (FGR) using Trio whole-exome sequencing (WES) with a normal chromosomal microarray....
This retrospective study analyzed WES results of singleton fetuses with isolated and severe FGR, whose estimated fetal weight (EFW) was less than the third percentile by Hadlock formula, in a tertiary...
Fifty-one fetuses with isolated and severe FGR and negative CMA results underwent Trio-WES. Of all patients, eight (15.7%) were diagnosed with FGR at its early onset (<32 weeks) and showed pathogenic ...
The present study indicates that Trio-WES can improve effectivity of prenatal diagnoses for isolated and severe FGR in cases with normal CMA results, aiding prenatal genetic counseling and pregnancy m...
Several studies have reported an association between residential surrounding particulate matter with an aerodynamic diameter ≤2.5 μm (PM...
To explore the prenatal clinical utility of chromosome microarray analysis (CMA) for polyhydramnios and evaluate the short and long-term prognosis of fetuses with polyhydramnios....
A total of 600 singleton pregnancies with persistent polyhydramnios from 2014 to 2020 were retrospectively enrolled in this study. All cases received amniocentesis and were subjected to CMA results. A...
The detection rates of either aneuploidy or pathogenic copy number variants in fetuses with non-isolated polyhydramnios were significantly higher than those with isolated polyhydramnios (5.0...
For low-risk pregnancies, invasive prenatal diagnosis of isolated polyhydramnios might be unnecessary. CMA should be considered for fetuses with structural anomalies. In CMA-negative cases, the progno...
To evaluate if the NT value of 2.5 mm ≤ NT < 3.0 mm is an appropriate indication for CMA tests among fetuses with isolated increased NT and NIPT is more suitable instead....
A total of 442 fetuses with NT ≥ 2.5 mm were included, in which 241 fetuses underwent karyotype. CMA tests were then carried out when cytogenic analysis showed normal chromosomes and CNV status was co...
Of the 241 fetuses with NT ≥ 2.5 mm, 47(19.50%) were identified by karyotype with chromosomal abnormalities. Among 194 cases with normal karyotype, CMA unraveled additional CNVs in 16(8.25%) cases, in...
While no pathogenic CNVs were detected in fetuses, chromosomal aneuploidies and genomic imbalance were found to be the major type of abnormalities when NT was 2.5-3.0 mm. Therefore, our data suggested...
Diabetic nephropathy (DN), which is the main cause of renal failure in end-stage renal disease, is becoming a common chronic renal disease worldwide. Mendelian randomization (MR) is a genetic tool tha...
Five DN gene expression datasets were selected from the Gene Expression Omnibus. The robust rank aggregation (RRA) method was used to integrate differentially expressed genes (DEGs) of glomerular samp...
A total of 82 DEGs (53 upregulated and 29 downregulated) were identified through RRA integrated analysis. The enriched Gene Ontology annotations and Kyoto Encyclopedia of Genes and Genomes pathways of...
Our integrated analysis identified novel biomarkers, including MICB and GZMA, which may help further understand the complicated mechanisms of DN and identify new target pathways for intervention....
Fetal hyperechogenic kidneys (HEK) is etiologically a heterogeneous disorder. The aim of this study was to identify the genetic causes of HEK using prenatal chromosomal microarray analysis (CMA) and e...