questionsmedicales.fr
Maladies du système immunitaire
Hypersensibilité
Hypersensibilité retardée
Hypersensibilité retardée : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hypersensibilité retardée
Tests cutanés
Tests de patch
Lymphocytes T
Éruption cutanée
Réaction allergique
Analyse sanguine
Inflammation
Antécédents médicaux
Allergènes
Symptômes
5
Éruption cutanée
Démangeaisons
Réaction retardée
Allergène
Symptômes systémiques
Fatigue
Réaction cutanée
Vésicules
Variabilité des symptômes
Réaction individuelle
Prévention
5
Tests d'allergie
Prévention des réactions
Changements de mode de vie
Allergènes alimentaires
Antihistaminiques
Prévention
Gestion des allergies
Médicaments d'urgence
Traitements
5
Corticostéroïdes
Évitement des allergènes
Antihistaminiques
Démangeaisons
Corticostéroïdes
Inflammation
Traitements topiques
Pommades corticostéroïdes
Traitement pédiatrique
Hypersensibilité
Complications
5
Infections cutanées
Complications
Maladies chroniques
Réactions répétées
Anaphylaxie
Réactions sévères
Qualité de vie
Démangeaisons
Hospitalisation
Traitement intensif
Facteurs de risque
5
Facteurs de risque
Antécédents d'allergies
Professions à risque
Produits chimiques
Antécédents familiaux
Allergies
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"name": "Comment diagnostiquer l'hypersensibilité retardée ?",
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"text": "Le diagnostic repose sur l'historique médical et des tests cutanés spécifiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests de patch et les tests de stimulation lymphocytaire sont couramment utilisés."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une hypersensibilité retardée ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des éruptions cutanées, démangeaisons et rougeurs apparaissent après exposition à l'allergène."
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"@type": "Question",
"name": "Peut-on diagnostiquer par des analyses sanguines ?",
"position": 4,
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"@type": "Question",
"name": "Quel rôle joue l'historique médical dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
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"text": "L'historique médical aide à identifier les allergènes potentiels et les antécédents d'exposition."
}
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{
"@type": "Question",
"name": "Quels sont les symptômes courants ?",
"position": 6,
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"@type": "Question",
"name": "Les symptômes apparaissent-ils immédiatement ?",
"position": 7,
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"text": "Non, ils apparaissent généralement 24 à 72 heures après l'exposition à l'allergène."
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"@type": "Question",
"name": "Y a-t-il des symptômes systémiques ?",
"position": 8,
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"@type": "Question",
"name": "Les symptômes varient-ils d'une personne à l'autre ?",
"position": 10,
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"text": "Oui, l'intensité et la nature des symptômes peuvent varier selon les individus."
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"@type": "Question",
"name": "Comment prévenir l'hypersensibilité retardée ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter l'exposition aux allergènes connus est la meilleure méthode de prévention."
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"@type": "Question",
"name": "Les tests d'allergie aident-ils à la prévention ?",
"position": 12,
"acceptedAnswer": {
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"text": "Oui, les tests d'allergie peuvent identifier les allergènes à éviter pour prévenir les réactions."
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"@type": "Question",
"name": "Les changements de mode de vie sont-ils nécessaires ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des changements de mode de vie, comme éviter certains aliments ou produits, peuvent être nécessaires."
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"@type": "Question",
"name": "Les médicaments préventifs sont-ils disponibles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antihistaminiques peuvent être pris en prévention avant une exposition connue."
}
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"@type": "Question",
"name": "Comment gérer les expositions accidentelles ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Avoir un plan d'action et des médicaments d'urgence peut aider à gérer les expositions accidentelles."
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"@type": "Question",
"name": "Quel est le traitement principal de l'hypersensibilité retardée ?",
"position": 16,
"acceptedAnswer": {
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"text": "Le traitement principal consiste en l'évitement de l'allergène et l'utilisation de corticostéroïdes."
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"@type": "Question",
"name": "Les antihistaminiques sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
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"text": "Les antihistaminiques peuvent soulager les démangeaisons, mais ne traitent pas la cause."
}
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"@type": "Question",
"name": "Comment les corticostéroïdes aident-ils ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les corticostéroïdes réduisent l'inflammation et soulagent les symptômes cutanés."
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"@type": "Question",
"name": "Y a-t-il des traitements topiques recommandés ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des crèmes ou pommades corticostéroïdes peuvent être appliquées sur les zones affectées."
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"@type": "Question",
"name": "Les traitements sont-ils différents pour les enfants ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction de l'âge et de la gravité des symptômes."
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"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des infections cutanées peuvent survenir si les lésions sont grattées."
}
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"@type": "Question",
"name": "L'hypersensibilité retardée peut-elle entraîner des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des réactions répétées peuvent contribuer à des maladies cutanées chroniques."
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"@type": "Question",
"name": "Y a-t-il un risque d'anaphylaxie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'anaphylaxie est rare dans l'hypersensibilité retardée, mais des réactions sévères peuvent survenir."
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"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications peuvent entraîner des douleurs, des démangeaisons et une gêne sociale."
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"@type": "Question",
"name": "Les complications nécessitent-elles une hospitalisation ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Dans certains cas graves, une hospitalisation peut être nécessaire pour un traitement intensif."
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"@type": "Question",
"name": "Quels sont les facteurs de risque principaux ?",
"position": 26,
"acceptedAnswer": {
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"text": "Les antécédents d'allergies, l'exposition répétée et la génétique sont des facteurs de risque."
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"@type": "Question",
"name": "L'âge influence-t-il le risque d'hypersensibilité ?",
"position": 27,
"acceptedAnswer": {
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"text": "Oui, les jeunes enfants et les personnes âgées peuvent être plus à risque."
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"text": "Certaines professions, comme celles en contact avec des produits chimiques, présentent un risque accru."
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"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut exacerber les symptômes et augmenter la sensibilité aux allergènes."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un historique familial d'allergies peut augmenter le risque d'hypersensibilité retardée."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 30/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Elizabeth.j.phillips@vumc.org.
Publications dans "Hypersensibilité retardée" :
3 publications dans cette catégorie
Affiliations :
Cancer Vaccine & Immune Cell Therapy Core Lab, Department of Medical Research, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department and Institute of Pharmacology, National Yang Ming Chiao Tung University, No.155, Sec.2, Linong Street, Taipei, 112 Taiwan. Electronic address: sihung@cgmh.org.tw.
Publications dans "Hypersensibilité retardée" :
3 publications dans cette catégorie
Affiliations :
Immunology and Infectious Diseases, Murdoch University, Murdoch, WA, Australia.
Clinical Immunology and Allergy, McGill University Health Center, Montréal, Canada.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Cancer Vaccine & Immune Cell Therapy Core Lab, Department of Medical Research, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Xiamen Chang Gung Hospital, No. 123, Xiafei Road, Haicang District, Xiamen, China.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Cancer Vaccine & Immune Cell Therapy Core Lab, Department of Medical Research, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou Branch, No. 5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan; Department of Dermatology, Xiamen Chang Gung Hospital, No. 123, Xiafei Road, Haicang District, Xiamen, China; Whole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Maijin Rd., Anle Dist., Keelung 204, Taiwan; College of Medicine, Chang Gung University, No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan 333, Taiwan. Electronic address: chung1@cgmh.org.tw.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
IRCCS Oasi Maria S.S., Troina, Italy.
Fondazione Mediterranea G.B. Morgagni, Italy.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
département de Dermatologie et Allergologie, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP.Sorbonne Université, Hôpital Tenon, Paris F75020, France. Electronic address: annick.barbaud@aphp.fr.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Faculty of Health Sciences, Universidad Europea de Valencia, 46010 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Faculty of Health Sciences, Universidad Europea de Valencia, 46010 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Pharmacy Unit, University General Hospital Consortium, 46014 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.
Research and Teaching Unit, University General Hospital Consortium, 46014 Valencia, Spain.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Immunology and Infectious Diseases, Murdoch University, Murdoch, WA, Australia.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Infectious Diseases, Austin Health, Center for Antibiotic Allergy and Research, Heidelberg, VIC, Australia.
Department of Oncology, Sir Peter MacCallum Cancer Center, The University of Melbourne, Parkville, VIC, Australia.
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, VIC, Australia.
The National Center for Infections in Cancer, Peter MacCallum Cancer Center, Melbourne, VIC, Australia.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Allergy, Zhongnan Hospital of Wuhan University, Wuhan, China.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, Jagiellonian University Medical College, 18 Czysta St., 31-121 Krakow, Poland.
Department of Immunology, Hospital de la Princesa, Health Research Institute of Princesa Hospital (ISS-IP), Autonomous University of Madrid, 28006 Madrid, Spain.
Section of Rheumatology, Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, CT 208011, USA.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, Jagiellonian University Medical College, 18 Czysta St., 31-121 Krakow, Poland.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Section of Rheumatology, Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, CT 208011, USA.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, Jagiellonian University Medical College, 18 Czysta St., 31-121 Krakow, Poland.
Section of Rheumatology, Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, CT 208011, USA.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Werner Siemens Imaging Center, Department of Preclinical Imaging and RadiopharmacyEberhard Karls University, 72076 Tübingen, Germany.
Publications dans "Hypersensibilité retardée" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, Eberhard Karls University, 72076 Tübingen, Germany.
Publications dans "Hypersensibilité retardée" :
Primary Sjogren's syndrome (pSS) is a heterogeneous chronic autoimmune disorder characterized by lymphocyte infiltration of the exocrine glands and the involvement and dysfunction of multiple organs a...
Eighty healthy controls and 142 patients diagnosed with pSS were included. The pSS patients were classified into groups with pSS-ILD or pSS without ILD (pSS-non-ILD). Baseline clinical and laboratory ...
The pSS-ILD patients were older, had higher ESSDAI scores, had higher positivity rates for anti-SSB and anti-Ro52 antibodies, and had more frequent symptoms of respiratory system involvement than pSS-...
Decreased circulating Th2 cells and an elevated Th1/Th2 ratio may be the immunological mechanism underlying the development of ILD in pSS patients....
Type 2 helper T (Th2) cells, a subset of CD4...
This study aimed to screen anaplasia-related genes that influence the progression of retinoblastoma (RB) and to identify immune cells associated with the poor prognosis....
Differentially expressed genes (DEGs) between retina and RB samples were acquired from gene expression omnibus (GEO) database. Candidate hub genes were screened by taking intersections among the co-ex...
665 DEGs involved in the genesis and progression of RB were acquired from GEO database. 29 candidate hub genes were screened by examining 43 co-expressed genes and 63 hub nodes. 9 hub genes (CHEK1, EX...
The increased infiltration of Th2 cells and upregulated expression of 9 hub genes predict a poor prognosis of RB. UBE2T can be a therapeutic target for RB treatment....
Dendritic cells (DCs) are antigen-presenting cells that drive the differentiation of T CD4+ cells into different profiles according to the nature of the antigen or immunomodulator. Propolis is a resin...
Immune response in the asthmatic respiratory tract is mainly driven by CD4...
Severe asthma and chronic obstructive pulmonary disease (COPD) share common pathophysiological traits such as relative corticosteroid insensitivity. We recently published three transcriptome-associate...
We examined whether gene expression signatures obtained in asthma can be used to identify the subgroup of patients with COPD with steroid sensitivity....
Using gene set variation analysis, we examined the distribution and enrichment scores (ES) of the 3 TACs in the transcriptome of bronchial biopsies from 46 patients who participated in the Groningen L...
Bronchial biopsies in patients with COPD at baseline showed a wide range of expression of the 3 TAC signatures. After ICS±LABA treatment, the ES of TAC1 was significantly reduced at 30 months, but tho...
Sputum-derived transcriptomic signatures from an asthma cohort can be recapitulated in bronchial biopsies of patients with COPD and identified a signature of airway mast cells as a predictor of cortic...
Th22 subset is a particular type of CD4...
Our study enrolled 43 newly diagnosed BC patients and 30 healthy controls. Frequencies of peripheral Th22, Th17, Th1, and Th2 cells were tested by flow cytometry. Concentrations of IL-22 cytokine in p...
Frequencies of Th22, Th17, Th2 subsets, and the plasma IL-22 level was obviously higher in the BC patients. A positive correlation between Th22 frequency and IL-22 concentration in plasma was detected...
Th22, Th17, Th1, and Th2 subsets may play an essential role in BC patients. Th22, Th17, Th1, and Th2 cells may have potential significance to be used as clinical markers in BC patients with different ...
Cell division cycle 42 (CDC42) regulates neurite outgrowth, neurotransmitter, and T help (Th) cell-mediated neuroinflammation, while its clinical implication in Alzheimer's disease (AD) is not clear. ...
150 AD patients were enrolled, then their blood Th1, Th2, and Th17 cells were quantified by flow cytometry at baseline; CDC42 was detected by RT-qPCR and MMSE score was assessed at baseline and during...
CDC42 (p < 0.001) and Th2 cells (p < 0.001) were lowest in AD patients, followed by PD patients, highest in HCs; but Th1 cells (p = 0.001) and Th17 cells (p < 0.001) showed opposite trends. CDC42 was ...
CDC42 might have the potency to serve as a biomarker for estimating AD risk and progression....
Cytokine secretion, such as interleukin-4 (IL-4), IL-5, IL-9, IL-13, and amphiregulin (Areg), by type 2 innate lymphoid cells (ILC2s) is indispensable for homeostasis, remodeling/repairing tissue stru...
Pregnenolone (P5) is synthesized as the first bioactive steroid in the mitochondria from cholesterol. Clusters of differentiation 4 (CD4+) and Clusters of differentiation 8 (CD8+) immune cells synthes...