questionsmedicales.fr
Maladies du système nerveux
Maladies du système nerveux central
Encéphalopathies
Maladies hypothalamiques
Maladies hypothalamiques : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Maladies hypothalamiques
Imagerie cérébrale
Imagerie par résonance magnétique
Hypothalamus
Symptômes
Régulation de la température
Tests génétiques
Maladies héréditaires
Symptômes
5
Symptômes
Troubles du sommeil
Température corporelle
Hyperthermie
Dysfonction sexuelle
Hormones
Troubles de l'humeur
Dépression
Prévention
5
Prévention
Mode de vie sain
Alimentation
Équilibre hormonal
Stress
Facteurs de risque
Antécédents familiaux
Maladies endocriniennes
Exercice physique
Régulation hormonale
Traitements
5
Thérapie hormonale
Chirurgie
Thérapie hormonale
Déséquilibres hormonaux
Chirurgie
Tumeurs hypophysaires
Médicaments
Gestion des symptômes
Thérapie comportementale
Médecine alternative
Complications
5
Complications
Troubles métaboliques
Fertilité
Déséquilibres hormonaux
Troubles de la croissance
Anomalies hypothalamiques
Problèmes cardiovasculaires
Déséquilibres hormonaux
Facteurs de risque
5
Facteurs de risque
Traumatismes crâniens
Obésité
Déséquilibres hormonaux
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Maladies hypothalamiques : Questions médicales les plus fréquentes",
"headline": "Maladies hypothalamiques : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Maladies hypothalamiques : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-04-12",
"dateModified": "2025-04-07",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Maladies hypothalamiques"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Encéphalopathies",
"url": "https://questionsmedicales.fr/mesh/D001927",
"about": {
"@type": "MedicalCondition",
"name": "Encéphalopathies",
"code": {
"@type": "MedicalCode",
"code": "D001927",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C10.228.140"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Maladies hypothalamiques",
"alternateName": "Hypothalamic Diseases",
"code": {
"@type": "MedicalCode",
"code": "D007027",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Åsa Petersén",
"url": "https://questionsmedicales.fr/author/%C3%85sa%20Peters%C3%A9n",
"affiliation": {
"@type": "Organization",
"name": "Translational Neuroendocrine Research Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden."
}
},
{
"@type": "Person",
"name": "Min-Seon Kim",
"url": "https://questionsmedicales.fr/author/Min-Seon%20Kim",
"affiliation": {
"@type": "Organization",
"name": "Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Ulsan College Medicine, Asan Medical Center, Seoul 05505, Korea."
}
},
{
"@type": "Person",
"name": "Sylvia L Asa",
"url": "https://questionsmedicales.fr/author/Sylvia%20L%20Asa",
"affiliation": {
"@type": "Organization",
"name": "Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada."
}
},
{
"@type": "Person",
"name": "Marianna Sadagurski",
"url": "https://questionsmedicales.fr/author/Marianna%20Sadagurski",
"affiliation": {
"@type": "Organization",
"name": ""
}
},
{
"@type": "Person",
"name": "Dongsheng Cai",
"url": "https://questionsmedicales.fr/author/Dongsheng%20Cai",
"affiliation": {
"@type": "Organization",
"name": "Department of Molecular Pharmacology, Diabetes Research Center, Institute of Aging, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: dongsheng.cai@einstein.yu.edu."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Impact of gender mismatch on corneal graft rejection and rejection-related graft failure in repeat penetrating keratoplasty.",
"datePublished": "2022-10-31",
"url": "https://questionsmedicales.fr/article/36315482",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1371/journal.pone.0276043"
}
},
{
"@type": "ScholarlyArticle",
"name": "Graft rejection episodes after keratoplasty in Japanese eyes.",
"datePublished": "2023-02-14",
"url": "https://questionsmedicales.fr/article/36788300",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1038/s41598-023-29659-w"
}
},
{
"@type": "ScholarlyArticle",
"name": "AIM2 as a putative target in acute kidney graft rejection.",
"datePublished": "2022-09-30",
"url": "https://questionsmedicales.fr/article/36248890",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3389/fimmu.2022.839359"
}
},
{
"@type": "ScholarlyArticle",
"name": "Epithelial downgrowth leading to graft rejection after penetrating keratoplasty.",
"datePublished": "2022-06-01",
"url": "https://questionsmedicales.fr/article/35651296",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1177/11206721221106314"
}
},
{
"@type": "ScholarlyArticle",
"name": "COVID-19 Vaccination May Not Increase Rates of Corneal Graft Rejection.",
"datePublished": "2022-08-10",
"url": "https://questionsmedicales.fr/article/35965396",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1097/ICO.0000000000003101"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Maladies du système nerveux",
"item": "https://questionsmedicales.fr/mesh/D009422"
},
{
"@type": "ListItem",
"position": 3,
"name": "Maladies du système nerveux central",
"item": "https://questionsmedicales.fr/mesh/D002493"
},
{
"@type": "ListItem",
"position": 4,
"name": "Encéphalopathies",
"item": "https://questionsmedicales.fr/mesh/D001927"
},
{
"@type": "ListItem",
"position": 5,
"name": "Maladies hypothalamiques",
"item": "https://questionsmedicales.fr/mesh/D007027"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Maladies hypothalamiques - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Maladies hypothalamiques",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-05",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Maladies hypothalamiques",
"description": "Comment diagnostique-t-on une maladie hypothalamique ?\nQuels tests hormonaux sont utilisés ?\nL'IRM est-elle utile pour ces maladies ?\nQuels symptômes peuvent alerter sur une maladie hypothalamique ?\nPeut-on utiliser des tests génétiques pour le diagnostic ?",
"url": "https://questionsmedicales.fr/mesh/D007027?mesh_terms=Graft+Rejection#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Maladies hypothalamiques",
"description": "Quels sont les symptômes courants des maladies hypothalamiques ?\nComment les maladies hypothalamiques affectent-elles la température corporelle ?\nLes troubles de la libido sont-ils fréquents ?\nPeut-on avoir des troubles de l'humeur ?\nLes maux de tête sont-ils un symptôme ?",
"url": "https://questionsmedicales.fr/mesh/D007027?mesh_terms=Graft+Rejection#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Maladies hypothalamiques",
"description": "Peut-on prévenir les maladies hypothalamiques ?\nL'alimentation joue-t-elle un rôle ?\nLe stress peut-il être un facteur de risque ?\nFaut-il surveiller les antécédents familiaux ?\nL'exercice physique est-il bénéfique ?",
"url": "https://questionsmedicales.fr/mesh/D007027?mesh_terms=Graft+Rejection#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Maladies hypothalamiques",
"description": "Quels traitements sont disponibles pour les maladies hypothalamiques ?\nLa thérapie hormonale est-elle efficace ?\nQuand la chirurgie est-elle nécessaire ?\nLes médicaments peuvent-ils aider ?\nY a-t-il des traitements alternatifs ?",
"url": "https://questionsmedicales.fr/mesh/D007027?mesh_terms=Graft+Rejection#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Maladies hypothalamiques",
"description": "Quelles complications peuvent survenir ?\nLes maladies hypothalamiques peuvent-elles affecter la fertilité ?\nY a-t-il un risque accru de diabète ?\nLes troubles de la croissance sont-ils possibles ?\nPeut-on avoir des problèmes cardiovasculaires ?",
"url": "https://questionsmedicales.fr/mesh/D007027?mesh_terms=Graft+Rejection#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Maladies hypothalamiques",
"description": "Quels sont les facteurs de risque des maladies hypothalamiques ?\nL'obésité est-elle un facteur de risque ?\nLes infections peuvent-elles jouer un rôle ?\nLe sexe influence-t-il le risque ?\nL'âge est-il un facteur de risque ?",
"url": "https://questionsmedicales.fr/mesh/D007027?mesh_terms=Graft+Rejection#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostique-t-on une maladie hypothalamique ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur l'examen clinique, l'imagerie cérébrale et des tests hormonaux."
}
},
{
"@type": "Question",
"name": "Quels tests hormonaux sont utilisés ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests mesurant les niveaux de cortisol, de prolactine et d'autres hormones sont effectués."
}
},
{
"@type": "Question",
"name": "L'IRM est-elle utile pour ces maladies ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IRM permet de visualiser des anomalies structurelles de l'hypothalamus."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent alerter sur une maladie hypothalamique ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles de la température, de l'appétit ou du sommeil peuvent indiquer une maladie."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser des tests génétiques pour le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des tests génétiques peuvent aider à identifier des causes héréditaires."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes courants des maladies hypothalamiques ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des troubles de l'appétit, des changements de poids et des troubles du sommeil."
}
},
{
"@type": "Question",
"name": "Comment les maladies hypothalamiques affectent-elles la température corporelle ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent provoquer des variations anormales de la température, comme l'hyperthermie."
}
},
{
"@type": "Question",
"name": "Les troubles de la libido sont-ils fréquents ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements sexuels peuvent survenir en raison de déséquilibres hormonaux."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des troubles de l'humeur ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles de l'humeur comme la dépression peuvent être liés à des maladies hypothalamiques."
}
},
{
"@type": "Question",
"name": "Les maux de tête sont-ils un symptôme ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maux de tête peuvent survenir, souvent liés à des déséquilibres hormonaux."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les maladies hypothalamiques ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies peuvent être évitées par un mode de vie sain et une gestion du stress."
}
},
{
"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation équilibrée peut aider à maintenir un bon équilibre hormonal."
}
},
{
"@type": "Question",
"name": "Le stress peut-il être un facteur de risque ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut contribuer à des déséquilibres hypothalamiques."
}
},
{
"@type": "Question",
"name": "Faut-il surveiller les antécédents familiaux ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies endocriniennes peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "L'exercice physique est-il bénéfique ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut aider à réguler les hormones et réduire le stress."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les maladies hypothalamiques ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des thérapies hormonales, des médicaments et parfois la chirurgie."
}
},
{
"@type": "Question",
"name": "La thérapie hormonale est-elle efficace ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut corriger les déséquilibres hormonaux et améliorer les symptômes."
}
},
{
"@type": "Question",
"name": "Quand la chirurgie est-elle nécessaire ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chirurgie est envisagée en cas de tumeurs ou d'anomalies structurelles significatives."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des médicaments peuvent être prescrits pour gérer les symptômes spécifiques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements alternatifs ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des approches comme la thérapie comportementale peuvent compléter les traitements médicaux."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles métaboliques, des problèmes de croissance et des troubles psychologiques."
}
},
{
"@type": "Question",
"name": "Les maladies hypothalamiques peuvent-elles affecter la fertilité ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent entraîner des problèmes de fertilité en raison de déséquilibres hormonaux."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de diabète ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles hypothalamiques peuvent augmenter le risque de diabète de type 2."
}
},
{
"@type": "Question",
"name": "Les troubles de la croissance sont-ils possibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies hypothalamiques peuvent entraîner des retards de croissance chez les enfants."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des problèmes cardiovasculaires ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déséquilibres hormonaux peuvent augmenter le risque de maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque des maladies hypothalamiques ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des traumatismes crâniens et des troubles endocriniens."
}
},
{
"@type": "Question",
"name": "L'obésité est-elle un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité peut contribuer à des déséquilibres hormonaux et à des maladies hypothalamiques."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles jouer un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales peuvent affecter l'hypothalamus et augmenter le risque."
}
},
{
"@type": "Question",
"name": "Le sexe influence-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies hypothalamiques peuvent être plus fréquentes chez un sexe spécifique."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies hypothalamiques sont plus fréquentes chez les personnes âgées."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 07/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Translational Neuroendocrine Research Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Publications dans "Maladies hypothalamiques" :
3 publications dans cette catégorie
Affiliations :
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Ulsan College Medicine, Asan Medical Center, Seoul 05505, Korea.
Publications dans "Maladies hypothalamiques" :
3 publications dans cette catégorie
Affiliations :
Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Publications dans "Maladies hypothalamiques" :
3 publications dans cette catégorie
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Pharmacology, Diabetes Research Center, Institute of Aging, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: dongsheng.cai@einstein.yu.edu.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Pharmacology, Diabetes Research Center, Institute of Aging, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Department of Paediatrics and Paediatric Hematology/Oncology, University Children's Hospital, Klinikum Oldenburg AöR, Carl von Ossietzky University, Oldenburg, Germany. mueller.hermann@klinikum-oldenburg.de.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Department of Paediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, Netherlands.
Princess Máxima Center for Paediatric Oncology, Utrecht, Netherlands.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Guro Hospital, Seoul 08308, Korea.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Brain Disease Biomarker Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, 221 84 Lund, Sweden. Electronic address: elna.dickson@med.lu.se.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Brain Disease Biomarker Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, 221 84 Lund, Sweden.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Brain Disease Biomarker Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A10, 221 84 Lund, Sweden.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Seattle Children's Research Institute, Department of Pediatrics, School of Medicine, University of Washington, Seattle, WA, United States.
Division of Endocrinology, Department of Pediatrics, University of Washington, Seattle, WA, United States.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Program of Material Science for Medicine and Pharmaceutics, Hallym University, Chuncheon, 24252, Korea.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Affiliations :
Pediatric Endocrinology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Publications dans "Maladies hypothalamiques" :
2 publications dans cette catégorie
Publications dans "Maladies hypothalamiques" :
To explore the impact of gender mismatch on corneal allograft rejection and rejection-related graft failure in patients with repeat penetrating keratoplasty (PK)....
A retrospective cohort was conducted at Ramathibodi Hospital, Bangkok, Thailand. Patients with repeat PK and follow-up period of at least 6 months were recruited. Demographic data, pre-operative ocula...
Of 68 patients with repeat PK, 26 patients (38.2%) were gender mismatched. There was no difference in 3-year rejection-free survival and graft survival between patients with gender mismatch and others...
Gender mismatch might not impact corneal graft rejection or rejection-related graft failure in patients with repeat PK. Younger age was found to be a strong factor associated with graft rejection. Gen...
We aimed to investigate the clinical characteristics and risk factors for graft rejection after keratoplasty in Japanese patients. We enrolled 730 cases (566 patients) of penetrating keratoplasty (PK,...
Acute rejection (AR) is a process triggered...
To report a case of epithelial downgrowth after penetrating keratoplasty....
A 58-year-old man presented with graft rejection in his three-month-old, repeat penetrating keratoplasty. Examination revealed centripetal opacification of the posterior cornea due to deep epithelizat...
Epithelial downgrowth is an uncommon complication of penetrating keratoplasty. It affects the patients' visual acuity and graft survival. Clinical observation is preferred in severe cases due to the h...
The aim of the study was to present the rates of rejection from 2018 to 2021 and evaluate the purported association between COVID-19 vaccination and corneal graft rejection....
Cases of corneal graft rejection diagnosed between January 2018 and December 2021 were reviewed. The conditional Poisson regression model of the self-controlled case series method was used to estimate...
Over the past 4 years, the annual tally of diagnosed cases of graft rejection (19 cases in year 2018, 19 cases in year 2019, 21 cases in year 2020, and 18 cases in year 2021) has remained relatively s...
No notable increase in rates of corneal graft rejection was noted in year 2021 when COVID-19 vaccination was broadly implemented. The apparent temporal relationship between COVID vaccination and corne...
To evaluate the association between donor-related factors and the risk of rejection in patients undergoing penetrating keratoplasty (PKP) for keratoconus....
A retrospective review was performed of keratoconus patients with no corneal neovascularization who underwent PKP from November 2014 to December 2016 and completed at least two years of follow-up. Pre...
A total of 201 eyes (of 201 patients) that underwent PKP for keratoconus were included. Of these, 22.9% (95% CI 17.6-29.2%) had an episode of graft rejection. The overall graft survival rate was 98.5%...
In the multivariable analysis, none of the donor-related factors were significantly associated with graft rejection; however, short death-to-surgery time may be associated with rejection after PKP. Re...
There are few predictive studies about early posttransplant outcomes taking into account baseline and posttransplant variables. The objective of this study was to create a predictive model for 30-day ...
Retrospective study with 1255 patients undergoing transplant from living and deceased donors at a tertiary health service in Brazil. Recipient, donor, transplantation, and postoperative period data we...
There were 147 (12.48%) cases of graft rejection within 30 days of transplantation. The best model was XGBoost (accuracy, 0.839; receiver operating characteristic area under the curve, 0.715; precisio...
We fitted a machine learning model to predict 30-day graft rejection after kidney transplantation that reaches a higher accuracy and precision. Machine learning models could contribute to predicting k...
Microvasculature consisting of endothelial cells and pericytes is the main site of injury during antibody-mediated rejection (ABMR) of renal grafts. Little is known about the mechanisms of activation ...
Rejection is one of the major factors affecting the long-term prognosis of kidney transplantation, and timely recognition and aggressive treatment of rejection is essential to prevent disease progress...
The complement system, consisting of more than thirty different soluble and cell-bound proteins, exerts essential functions both in the innate and adaptive immune systems and is believed to be an impo...
In this case-control feasibility study, complement factors C3a, C3dg, C4a, and C5a were measured in plasma and C3dg and sC5b-9 associated C9 neoantigen in urine in 15 kidney transplant recipients with...
In plasma, there were no significant differences between the rejection and the control group. However, steroids and pretransplant C3dg levels significantly influenced C3dg. Within the rejection group,...
This study shows increased plasma C3a and C3dg in kidney transplant recipients, primarily with T cell mediated rejection. This finding suggests that consecutive measurements of C3a and C3dg in plasma ...