{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Lévorphanol : Questions médicales les plus fréquentes",
"headline": "Lévorphanol : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Lévorphanol : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-06-13",
"dateModified": "2025-03-10",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Lévorphanol"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Morphinanes",
"url": "https://questionsmedicales.fr/mesh/D009019",
"about": {
"@type": "MedicalCondition",
"name": "Morphinanes",
"code": {
"@type": "MedicalCode",
"code": "D009019",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D04.615.723.795"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Lévorphanol",
"alternateName": "Levorphanol",
"code": {
"@type": "MedicalCode",
"code": "D007981",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Ali Haider",
"url": "https://questionsmedicales.fr/author/Ali%20Haider",
"affiliation": {
"@type": "Organization",
"name": "Department of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA."
}
},
{
"@type": "Person",
"name": "Akhila Reddy",
"url": "https://questionsmedicales.fr/author/Akhila%20Reddy",
"affiliation": {
"@type": "Organization",
"name": "Department of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. asreddy@mdanderson.org."
}
},
{
"@type": "Person",
"name": "Valerie Le Rouzic",
"url": "https://questionsmedicales.fr/author/Valerie%20Le%20Rouzic",
"affiliation": {
"@type": "Organization",
"name": "From the Department of Neurology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York."
}
},
{
"@type": "Person",
"name": "Ankita Narayan",
"url": "https://questionsmedicales.fr/author/Ankita%20Narayan",
"affiliation": {
"@type": "Organization",
"name": "From the Department of Neurology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York."
}
},
{
"@type": "Person",
"name": "Amanda Hunkle",
"url": "https://questionsmedicales.fr/author/Amanda%20Hunkle",
"affiliation": {
"@type": "Organization",
"name": "From the Department of Neurology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Distinct approaches (antecolic and retrocolic) according to tumor location in laparoscopic and endoscopic cooperative surgery for non-ampullary duodenum tumors.",
"datePublished": "2023-05-22",
"url": "https://questionsmedicales.fr/article/37217687",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s00464-023-10114-w"
}
},
{
"@type": "ScholarlyArticle",
"name": "Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique.",
"datePublished": "2023-08-23",
"url": "https://questionsmedicales.fr/article/37625656",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ejpb.2023.08.011"
}
},
{
"@type": "ScholarlyArticle",
"name": "A case of pyloric gland adenoma with high-grade dysplasia in the duodenum arising from heterotopic gastric mucosa observed over 5 years.",
"datePublished": "2022-10-28",
"url": "https://questionsmedicales.fr/article/36306058",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s12328-022-01721-6"
}
},
{
"@type": "ScholarlyArticle",
"name": "Robotic distal pancreas-sparing duodenectomy (duodenal sleeve resection) with transmesenteric approach: robotic approach for tumors in the third and fourth parts of the duodenum.",
"datePublished": "2023-01-11",
"url": "https://questionsmedicales.fr/article/36631534",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s00464-022-09841-3"
}
},
{
"@type": "ScholarlyArticle",
"name": "Intracapsular approach used in laparoscopic duodenum-preserving total pancreatic head resection for pancreatic head benign or low-grade malignant tumors.",
"datePublished": "2022-09-24",
"url": "https://questionsmedicales.fr/article/36152046",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s00423-022-02509-5"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Composés polycycliques",
"item": "https://questionsmedicales.fr/mesh/D011083"
},
{
"@type": "ListItem",
"position": 3,
"name": "Hydrocarbures aromatiques polycycliques",
"item": "https://questionsmedicales.fr/mesh/D011084"
},
{
"@type": "ListItem",
"position": 4,
"name": "Phénanthrènes",
"item": "https://questionsmedicales.fr/mesh/D010616"
},
{
"@type": "ListItem",
"position": 5,
"name": "Morphinanes",
"item": "https://questionsmedicales.fr/mesh/D009019"
},
{
"@type": "ListItem",
"position": 6,
"name": "Lévorphanol",
"item": "https://questionsmedicales.fr/mesh/D007981"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Lévorphanol - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Lévorphanol",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-02",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Lévorphanol",
"description": "Comment diagnostiquer une douleur nécessitant du lévorphanol ?\nQuels tests sont utilisés pour évaluer la douleur ?\nLe lévorphanol est-il prescrit pour tous les types de douleur ?\nQuels critères déterminent l'utilisation du lévorphanol ?\nLe lévorphanol est-il utilisé en cas de douleur chronique ?",
"url": "https://questionsmedicales.fr/mesh/D007981?mesh_terms=Duodenum&page=3#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Lévorphanol",
"description": "Quels sont les effets secondaires du lévorphanol ?\nLe lévorphanol peut-il provoquer des réactions allergiques ?\nQuels symptômes indiquent une surdose de lévorphanol ?\nComment reconnaître une dépendance au lévorphanol ?\nLe lévorphanol peut-il affecter l'humeur ?",
"url": "https://questionsmedicales.fr/mesh/D007981?mesh_terms=Duodenum&page=3#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Lévorphanol",
"description": "Comment prévenir les effets secondaires du lévorphanol ?\nQuelles précautions prendre avant de commencer le lévorphanol ?\nLe lévorphanol est-il sûr pour les personnes âgées ?\nComment éviter la dépendance au lévorphanol ?\nQuelles alternatives au lévorphanol existent ?",
"url": "https://questionsmedicales.fr/mesh/D007981?mesh_terms=Duodenum&page=3#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Lévorphanol",
"description": "Comment le lévorphanol est-il administré ?\nQuelle est la posologie habituelle du lévorphanol ?\nLe lévorphanol peut-il être combiné avec d'autres analgésiques ?\nQuels sont les risques d'un traitement prolongé au lévorphanol ?\nComment arrêter le lévorphanol en toute sécurité ?",
"url": "https://questionsmedicales.fr/mesh/D007981?mesh_terms=Duodenum&page=3#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Lévorphanol",
"description": "Quelles complications peuvent survenir avec le lévorphanol ?\nLe lévorphanol peut-il interagir avec d'autres médicaments ?\nComment gérer une réaction allergique au lévorphanol ?\nQuels sont les signes d'une surdose de lévorphanol ?\nLe lévorphanol peut-il causer des problèmes cardiaques ?",
"url": "https://questionsmedicales.fr/mesh/D007981?mesh_terms=Duodenum&page=3#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Lévorphanol",
"description": "Qui est à risque de dépendance au lévorphanol ?\nLes jeunes adultes sont-ils plus à risque avec le lévorphanol ?\nQuels facteurs augmentent le risque d'effets secondaires ?\nLe lévorphanol est-il risqué pour les femmes enceintes ?\nLes personnes ayant des problèmes respiratoires sont-elles à risque ?",
"url": "https://questionsmedicales.fr/mesh/D007981?mesh_terms=Duodenum&page=3#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une douleur nécessitant du lévorphanol ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un diagnostic se fait par évaluation clinique et historique médical du patient."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer la douleur ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des échelles de douleur et des examens physiques sont utilisés pour évaluer l'intensité."
}
},
{
"@type": "Question",
"name": "Le lévorphanol est-il prescrit pour tous les types de douleur ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, il est principalement utilisé pour la douleur modérée à sévère, pas pour la douleur légère."
}
},
{
"@type": "Question",
"name": "Quels critères déterminent l'utilisation du lévorphanol ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les critères incluent l'intensité de la douleur et la réponse aux traitements antérieurs."
}
},
{
"@type": "Question",
"name": "Le lévorphanol est-il utilisé en cas de douleur chronique ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut être utilisé pour la douleur chronique lorsque d'autres traitements échouent."
}
},
{
"@type": "Question",
"name": "Quels sont les effets secondaires du lévorphanol ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires incluent la somnolence, la constipation et des nausées."
}
},
{
"@type": "Question",
"name": "Le lévorphanol peut-il provoquer des réactions allergiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des réactions allergiques peuvent survenir, bien que rares."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une surdose de lévorphanol ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent la dépression respiratoire, la somnolence excessive et la confusion."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une dépendance au lévorphanol ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes de dépendance incluent le besoin compulsif de médicament et des symptômes de sevrage."
}
},
{
"@type": "Question",
"name": "Le lévorphanol peut-il affecter l'humeur ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut provoquer des changements d'humeur, y compris l'euphorie ou la dépression."
}
},
{
"@type": "Question",
"name": "Comment prévenir les effets secondaires du lévorphanol ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une surveillance régulière et l'ajustement de la posologie peuvent aider à prévenir les effets secondaires."
}
},
{
"@type": "Question",
"name": "Quelles précautions prendre avant de commencer le lévorphanol ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Informez votre médecin de vos antécédents médicaux et des médicaments que vous prenez."
}
},
{
"@type": "Question",
"name": "Le lévorphanol est-il sûr pour les personnes âgées ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il doit être utilisé avec prudence chez les personnes âgées en raison du risque accru d'effets secondaires."
}
},
{
"@type": "Question",
"name": "Comment éviter la dépendance au lévorphanol ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utilisez-le uniquement selon les prescriptions et évitez l'auto-médication."
}
},
{
"@type": "Question",
"name": "Quelles alternatives au lévorphanol existent ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des alternatives incluent d'autres analgésiques opioïdes ou des traitements non opioïdes."
}
},
{
"@type": "Question",
"name": "Comment le lévorphanol est-il administré ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est généralement administré par voie orale ou intraveineuse selon la situation clinique."
}
},
{
"@type": "Question",
"name": "Quelle est la posologie habituelle du lévorphanol ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La posologie varie, mais commence souvent à 2-4 mg toutes les 6-8 heures selon la douleur."
}
},
{
"@type": "Question",
"name": "Le lévorphanol peut-il être combiné avec d'autres analgésiques ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut être utilisé en association avec d'autres analgésiques pour un meilleur contrôle de la douleur."
}
},
{
"@type": "Question",
"name": "Quels sont les risques d'un traitement prolongé au lévorphanol ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un traitement prolongé peut entraîner une tolérance, une dépendance et des effets secondaires accrus."
}
},
{
"@type": "Question",
"name": "Comment arrêter le lévorphanol en toute sécurité ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'arrêt doit être progressif sous supervision médicale pour éviter les symptômes de sevrage."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le lévorphanol ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la dépression respiratoire, la constipation sévère et la dépendance."
}
},
{
"@type": "Question",
"name": "Le lévorphanol peut-il interagir avec d'autres médicaments ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut interagir avec d'autres médicaments, augmentant le risque d'effets indésirables."
}
},
{
"@type": "Question",
"name": "Comment gérer une réaction allergique au lévorphanol ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "En cas de réaction allergique, arrêtez le médicament et consultez immédiatement un médecin."
}
},
{
"@type": "Question",
"name": "Quels sont les signes d'une surdose de lévorphanol ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes incluent la somnolence extrême, la confusion et la difficulté à respirer."
}
},
{
"@type": "Question",
"name": "Le lévorphanol peut-il causer des problèmes cardiaques ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il peut provoquer des problèmes cardiaques chez certains patients, surtout en cas de surdose."
}
},
{
"@type": "Question",
"name": "Qui est à risque de dépendance au lévorphanol ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes ayant des antécédents de dépendance ou de troubles de l'humeur sont à risque."
}
},
{
"@type": "Question",
"name": "Les jeunes adultes sont-ils plus à risque avec le lévorphanol ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les jeunes adultes peuvent être plus susceptibles de développer une dépendance aux opioïdes."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'effets secondaires ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge avancé, les maladies chroniques et l'utilisation concomitante d'autres médicaments augmentent le risque."
}
},
{
"@type": "Question",
"name": "Le lévorphanol est-il risqué pour les femmes enceintes ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut présenter des risques pour le fœtus et doit être évité sauf en cas de nécessité."
}
},
{
"@type": "Question",
"name": "Les personnes ayant des problèmes respiratoires sont-elles à risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont à risque accru de dépression respiratoire lors de l'utilisation de lévorphanol."
}
}
]
}
]
}
Laparoscopic and endoscopic cooperative surgery for early non-ampullary duodenum tumors (D-LECS) is now noted because of its safety and lower invasiveness. Here, we introduce two distinct approaches (...
From October 2018 to March 2022, 24 patients (25 lesions) underwent D-LECS. Two (8%), two (8%), 16 (64%), and five (20%) lesions were located in the first portion, in the second portion to Vater's pap...
Antecolic and retrocolic approaches were employed in 16 (67%) and 8 (33%) cases, respectively. LECS procedures, such as two-layer suturing after full-thickness dissection and laparoscopic reinforcemen...
D-LECS can be a safe and minimally invasive treatment option for non-ampullary early duodenal tumors, and two distinct approaches according to the tumor location are feasible....
Characterising the small intestine absorptive membrane is essential to enable prediction of the systemic exposure of oral formulations. In particular, the ontogeny of key intestinal Drug Metabolising ...
Pyloric gland adenoma (PGA) in the duodenum is a rare gastric phenotype duodenal neoplasm. Although heterotopic gastric mucosa in the duodenum has been recognized as a benign lesion, it is a potential...
Minimally invasive resection of the retroperitoneal duodenum is complicated because of its anatomical location, and the proximity of the ampulla of Vater and vascular structures. Benign or indolent pa...
A retrospective review was performed on a prospectively maintained institutional database between 2011 and 2021. The Da Vinci XI or SI platform (Intuitive Surgical, Sunnyvale, CA) was used in all case...
Critical steps in robotic sleeve duodenectomy include the following: (1) techniques for avoiding damage to the ampulla; (2) Kocherization and reverse Kocherization; and (3) A transmesenteric approach ...
This small case series of a transmesenteric approach for robotic sleeve duodenectomy demonstrates its feasibility and safety in this potentially challenging operation....
Laparoscopic duodenum-preserving total pancreatic head resection (LDPPHRt) is used for treating benign or low-grade malignant tumors of the pancreatic head. However, preservation of the duodenum and b...
From April 2020 to December 2020, 30 patients successfully underwent LDPPHRt using the intracapsular approach in our center. Their medical records were reviewed for relevant clinical characteristics, ...
The median diameter of the lesions was 3.6 cm (range, 2.0-5.5 cm). The median operative time was 234.7 min (range, 195-310 min). The median blood loss was 66.7 ml (range, 20-250 ml). The morbidity rat...
The intracapsular approach is a feasible and safe surgical procedure in LDPPHRt for patients with benign or low-grade malignant tumors, especially those without severe pancreatic head fibrosis or peri...
The risk factors for achieving textbook outcome (TO) after laparoscopic duodenum-preserving total pancreatic head resection (LDPPHR-t) are unknown, and no relevant articles have been reported so far. ...
The risk factors for achieving TO after LDPPHR-t were retrospectively evaluated by logistic regression analysis in 31 consecutive patients from May 2020 to December 2021....
All LDPPHR-t procedures were successfully performed without conversion. There was no death within 90 days after surgery and no readmission within 30 days after discharge. The percentage of achieving T...
Placing the ENBD catheter was the independent risk factor for POPF and achieving TO after LDPPHR-t. In order to reduce POPF and increase the probability of achieving TO, placing an ENBD catheter shoul...
Currently, no literature specifically addresses the curative efficacy of laparoscopic duodenum-preserving total pancreatic head resection (LDPPHRt) in the treatment of pancreatic-head intraductal papi...
We retrospectively reviewed patients undergoing LDPPHRt or LPD for pancreatic-head IPMN in our institution between September 2014 and October 2020. We collected, analyzed and compared preoperative, in...
In total, 50 patients were incorporated into this study, which included 12 LDPPHRt patients and 38 LPD patients. Preoperative data was comparable in the two groups, and neither was there any significa...
Perioperative outcomes for LDPPHRt were comparable to those for LPD, but the quality of life after operation was better in the LDPPHRt group....
Germ cell tumors are the most common malignancies in males between 20 and 40 years. However, primary extragonadal germ cell tumors are rare and account for 2%-5% of all germ cell neoplasms in adults. ...
The primary aim was to assess Health Related Quality of Life (HRQoL), anxiety and depression in patients and caregivers during follow-up care after curative treatment for cancer in the pancreas, duode...
In this prospective observational cohort study, we included patients and caregivers at first follow-up visit to conduct the following: Demographic characteristics, The European Organization for Resear...
The response rate was 42% with 104 of the 248 invited patients completing the questionnaires at baseline: 78 (75% of 104) after six and 69 (66% of 104) after nine months. The median (Q25,75) time for ...
The study highlights the need to systematically screen physical and psychological symptoms in patients and caregivers during follow-up care after treatment for cancer in the pancreas, duodenum and bil...
Laparoscopic duodenum-preserving pancreatic head resection (L-DPPHR) is technically demanding with extreme difficulty in biliary preservation. Only a few reports of L-DPPHR are available with alarming...
Between October 2015 and January 2021, different dosage and timing of ICG were administrated preoperatively and evaluated intra-operatively using Image J software to calculate the relative fluorescenc...
Twenty-five patients were enrolled without conversion to laparotomy or pancreaticoduodenectomy. Administrating a dosage of 0.5 mg/kg 24 h before the operation had the highest relative fluorescence int...
L-DPPHR is feasible and safe in selected patients, and real-time ICG imaging with proper dosage and timing may greatly facilitate the identification and the prevention of biliary injury. And it seemed...