Titre : Menthol

Menthol : Questions médicales fréquentes

Termes MeSH sélectionnés :

Quantitative Structure-Activity Relationship
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démangeaisons, rougeurs ou éruptions cutanées peuvent survenir en cas d'allergie." } }, { "@type": "Question", "name": "Le menthol peut-il provoquer des maux de tête ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines personnes peuvent ressentir des maux de tête après exposition au menthol." } }, { "@type": "Question", "name": "Comment éviter les réactions allergiques au menthol ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Évitez les produits contenant du menthol si vous avez des antécédents d'allergies." } }, { "@type": "Question", "name": "Le menthol peut-il être utilisé en prévention des infections ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Le menthol a des propriétés antimicrobiennes, mais ne remplace pas les traitements médicaux." } }, { "@type": "Question", "name": "Comment le menthol est-il utilisé pour soulager la douleur ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Le menthol est appliqué localement pour créer une sensation de froid, réduisant ainsi la douleur." } }, { "@type": "Question", "name": "Le menthol est-il efficace contre la toux ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le menthol est souvent utilisé dans les sirops pour apaiser la toux et les irritations." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec une surconsommation de menthol ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Une surconsommation peut entraîner des irritations cutanées ou des troubles gastro-intestinaux." } }, { "@type": "Question", "name": "Le menthol peut-il aggraver l'asthme ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Chez certaines personnes, le menthol peut provoquer des spasmes bronchiques et aggraver l'asthme." } }, { "@type": "Question", "name": "Qui est à risque d'allergie au menthol ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Les personnes ayant des antécédents d'allergies cutanées ou respiratoires sont à risque." } }, { "@type": "Question", "name": "Le menthol est-il risqué pour les enfants ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les enfants peuvent être plus sensibles aux effets du menthol, nécessitant prudence." } } ] } ] }

Sources (10000 au total)

Design, Synthesis, Antibacterial Evaluation, Three-Dimensional Quantitative Structure-Activity Relationship, and Mechanism of Novel Quinazolinone Derivatives.

Plant bacterial illnesses are common and cause dramatic damage to agricultural goods all over the world, yet there are few efficient bactericides to alleviate them at present. To discover novel antiba...

Automated machine learning approach for developing a quantitative structure-activity relationship model for cardiac steroid inhibition of Na

Quantitative structure-activity relationship (QSAR) modeling is a method of characterizing the relationship between chemical structures and biological activity. Automated machine learning enables comp... The chemical structures and inhibitory activities of 215 CS derivatives were obtained from the scientific literature. Predictive QSAR models were constructed using molecular descriptors, fingerprints,... The best predictive QSAR models were selected based on the LogLoss value. Using these models, the Matthews correlation coefficient, F1 score, and area under the curve of the test dataset were 0.6729, ... The automated machine learning-based QSAR method developed here should be applicable for the time-efficient construction of predictive models using only a small number of compounds....

Multivariate image analysis applied to quantitative structure-activity relationships and docking studies of recent hydroxyphenylpyruvate deoxygenase inhibitors.

Mesotrione is a triketone widely used as an inhibitor of the hydroxyphenylpyruvate deoxygenase (HPPD) enzyme. However, new agrochemicals should be developed continuously to tackle the problem of herbi... The MIA-QSAR models based on van der Waals radii (r... Multivariate image analysis descriptors corroborated by docking studies were capable of modeling the herbicidal activities of 68 triketones reliably. Due to the substituent effects at the triketone fr...

Artificial Intelligence-Based Quantitative Structure-Property Relationship Model for Predicting Human Intestinal Absorption of Compounds with Serotonergic Activity.

Oral medicines represent the largest pharmaceutical market area. To achieve a therapeutic effect, a drug must penetrate the intestinal walls, the main absorption site for orally delivered active pharm...

Development of a quantitative structure-activity relationship model for predicting quantum yield of hydroxyl radical generation from organic compounds.

Organic compounds are capable of generating hydroxyl radicals (˙OH) through their excited triplet states in natural water. It is of significance to reveal the underlying mechanism of the generation an...

In vitro and Quantitative and Structure Activity Relationship (QSAR) evaluation of the antifungal activity of terpenoid constituents of essential oils against Alternaria alternata and Fusarium oxysporum

Fungal genera Alternaria and Fusarium include human and plant pathogenic species. Several antifungals have been used for their control, but excessive use has contributed to resistance development in p... To evaluate in vitro and in silico the antifungal activities of terpenoids against Alternaria alternata and Fusarium oxysporum.... The minimum inhibitory concentration and minimum fungicidal concentration values of 27 constituents of essential oils used against Alternaria alternata and Fusarium oxysporum were evaluated in vitro. ... The evaluated compounds proved to be effective antifungals. Thymol was the most active with a minimum inhibitory concentration of 91.6 ± 28.8 μg/ml for A. alternata and F. oxysporum. Quantitative stru... Terpenoids exhibit relevant antifungal activities that should be incorporated into the study of medicinal chemistry. Inclusion of in silico assays in the in vitro evaluation is a valuable tool in the ...

Three-dimensional quantitative structural-activity relationship and molecular dynamics study of multivariate substituted 4-oxyquinazoline HDAC6 inhibitors.

3D-QSAR models were established by collecting 46 multivariate-substituted 4-oxyquinazoline HDAC6 inhibitors. The relationship of molecular structure and inhibitory activity was studied by comparative ...

Identification of Potent Small-Molecule PCSK9 Inhibitors Based on Quantitative Structure-Activity Relationship, Pharmacophore Modeling, and Molecular Docking Procedure.

The leading cause of atherosclerotic cardiovascular disease (ASCVD) is elevated low-density lipoprotein cholesterol (LDL-C). Proprotein convertase subtilisin/kexin type 9 (PCSK9) attaches to the domai...

An Empirical Quantitative Structure-Activity Relationship Equation Assists the Discovery of High-Affinity Phosphodiesterase 4D Inhibitors as Leads to PET Radioligands.

A positron emission tomography (PET) radioligand for imaging phosphodiesterase 4D (PDE4D) would benefit drug discovery and the investigation of neuropsychiatric disorders. The most promising radioliga...