Titre : Inhibiteurs de la monoamine oxydase

Inhibiteurs de la monoamine oxydase : Questions médicales fréquentes

Termes MeSH sélectionnés :

Benzhydryl Compounds
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"@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Inhibiteurs de la monoamine oxydase", "description": "Quels symptômes indiquent un besoin d'IMAO ?\nLes IMAO peuvent-ils aggraver certains symptômes ?\nQuels symptômes d'interaction médicamenteuse avec les IMAO ?\nLes IMAO affectent-ils l'appétit ?\nQuels symptômes de sevrage des IMAO ?", "url": "https://questionsmedicales.fr/mesh/D008996?mesh_terms=Benzhydryl+Compounds&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Inhibiteurs de la monoamine oxydase", "description": "Comment prévenir les effets secondaires des IMAO ?\nY a-t-il des mesures préventives avant de commencer un IMAO ?\nComment éviter les interactions médicamenteuses avec les IMAO ?\nLes patients doivent-ils être éduqués sur les IMAO ?\nQuelles sont les recommandations alimentaires pour les patients sous IMAO ?", "url": "https://questionsmedicales.fr/mesh/D008996?mesh_terms=Benzhydryl+Compounds&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Inhibiteurs de la monoamine oxydase", "description": "Comment fonctionnent les IMAO dans le traitement de la dépression ?\nQuels sont les principaux IMAO disponibles ?\nComment prendre des IMAO en toute sécurité ?\nLes IMAO nécessitent-ils des ajustements de dose ?\nLes IMAO sont-ils efficaces à long terme ?", "url": "https://questionsmedicales.fr/mesh/D008996?mesh_terms=Benzhydryl+Compounds&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Inhibiteurs de la monoamine oxydase", "description": "Quelles sont les complications possibles des IMAO ?\nComment gérer une crise hypertensive due aux IMAO ?\nLes IMAO peuvent-ils causer des problèmes cardiaques ?\nQuels sont les signes d'une réaction allergique aux IMAO ?\nLes IMAO peuvent-ils interférer avec d'autres traitements ?", "url": "https://questionsmedicales.fr/mesh/D008996?mesh_terms=Benzhydryl+Compounds&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Inhibiteurs de la monoamine oxydase", "description": "Quels sont les facteurs de risque pour les effets secondaires des IMAO ?\nLes antécédents familiaux influencent-ils l'utilisation des IMAO ?\nLe mode de vie affecte-t-il l'efficacité des IMAO ?\nLes interactions alimentaires sont-elles un facteur de risque ?\nLes patients ayant des troubles psychiatriques sont-ils à risque ?", "url": "https://questionsmedicales.fr/mesh/D008996?mesh_terms=Benzhydryl+Compounds&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dépression nécessitant des IMAO ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Un diagnostic est basé sur des critères cliniques, l'historique médical et des évaluations psychologiques." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour évaluer l'efficacité des IMAO ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des échelles d'évaluation de la dépression et des suivis cliniques réguliers sont utilisés." } }, { "@type": "Question", "name": "Les IMAO sont-ils prescrits pour d'autres troubles ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent être utilisés pour des troubles anxieux et certains troubles alimentaires." } }, { "@type": "Question", "name": "Comment évaluer les effets secondaires des IMAO ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les effets secondaires sont évalués par des consultations régulières et des questionnaires." } }, { "@type": "Question", "name": "Les IMAO nécessitent-ils un suivi médical ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un suivi médical est essentiel pour ajuster le traitement et surveiller les effets." } }, { "@type": "Question", "name": "Quels symptômes indiquent un besoin d'IMAO ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent une humeur dépressive persistante, une perte d'intérêt et des troubles du sommeil." } }, { "@type": "Question", "name": "Les IMAO peuvent-ils aggraver certains symptômes ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent aggraver l'anxiété ou provoquer des effets indésirables comme des maux de tête." } }, { "@type": "Question", "name": "Quels symptômes d'interaction médicamenteuse avec les IMAO ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes comme des palpitations, des maux de tête ou une hypertension peuvent survenir." } }, { "@type": "Question", "name": "Les IMAO affectent-ils l'appétit ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent provoquer une augmentation ou une diminution de l'appétit chez certains patients." } }, { "@type": "Question", "name": "Quels symptômes de sevrage des IMAO ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes de sevrage peuvent inclure des vertiges, des nausées et des troubles de l'humeur." } }, { "@type": "Question", "name": "Comment prévenir les effets secondaires des IMAO ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les aliments riches en tyramine et suivre les recommandations médicales aide à prévenir les effets secondaires." } }, { "@type": "Question", "name": "Y a-t-il des mesures préventives avant de commencer un IMAO ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une évaluation complète de l'historique médical et des médicaments en cours est nécessaire." } }, { "@type": "Question", "name": "Comment éviter les interactions médicamenteuses avec les IMAO ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Informer le médecin de tous les médicaments pris et éviter les médicaments non prescrits." } }, { "@type": "Question", "name": "Les patients doivent-ils être éduqués sur les IMAO ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'éducation des patients sur les IMAO et leurs effets est essentielle pour une utilisation sécurisée." } }, { "@type": "Question", "name": "Quelles sont les recommandations alimentaires pour les patients sous IMAO ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les aliments fermentés, les fromages vieillis et les boissons alcoolisées est recommandé." } }, { "@type": "Question", "name": "Comment fonctionnent les IMAO dans le traitement de la dépression ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Ils bloquent l'enzyme monoamine oxydase, augmentant les niveaux de neurotransmetteurs comme la sérotonine." } }, { "@type": "Question", "name": "Quels sont les principaux IMAO disponibles ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Les principaux IMAO incluent la phénelzine, la tranylcypromine et l'isocarboxazide." } }, { "@type": "Question", "name": "Comment prendre des IMAO en toute sécurité ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Il est crucial de suivre les instructions du médecin et d'éviter certains aliments et médicaments." } }, { "@type": "Question", "name": "Les IMAO nécessitent-ils des ajustements de dose ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des ajustements peuvent être nécessaires en fonction de la réponse du patient et des effets secondaires." } }, { "@type": "Question", "name": "Les IMAO sont-ils efficaces à long terme ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent être efficaces à long terme, mais un suivi régulier est nécessaire pour évaluer leur efficacité." } }, { "@type": "Question", "name": "Quelles sont les complications possibles des IMAO ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent l'hypertension, les crises hypertensives et des troubles gastro-intestinaux." } }, { "@type": "Question", "name": "Comment gérer une crise hypertensive due aux IMAO ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Une crise hypertensive nécessite une intervention médicale immédiate et un traitement antihypertenseur." } }, { "@type": "Question", "name": "Les IMAO peuvent-ils causer des problèmes cardiaques ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent augmenter le risque de problèmes cardiaques, surtout en cas d'interactions médicamenteuses." } }, { "@type": "Question", "name": "Quels sont les signes d'une réaction allergique aux IMAO ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Les signes incluent des éruptions cutanées, des démangeaisons et des difficultés respiratoires." } }, { "@type": "Question", "name": "Les IMAO peuvent-ils interférer avec d'autres traitements ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent interférer avec d'autres traitements, nécessitant une évaluation médicale approfondie." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les effets secondaires des IMAO ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'âge avancé, des antécédents de maladies cardiaques et d'autres médicaments." } }, { "@type": "Question", "name": "Les antécédents familiaux influencent-ils l'utilisation des IMAO ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents familiaux de dépression ou de troubles mentaux peuvent influencer la décision de traitement." } }, { "@type": "Question", "name": "Le mode de vie affecte-t-il l'efficacité des IMAO ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie sain peut améliorer l'efficacité des IMAO et réduire les effets secondaires." } }, { "@type": "Question", "name": "Les interactions alimentaires sont-elles un facteur de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la consommation d'aliments riches en tyramine peut augmenter le risque d'effets indésirables." } }, { "@type": "Question", "name": "Les patients ayant des troubles psychiatriques sont-ils à risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les patients avec des troubles psychiatriques peuvent avoir un risque accru d'effets secondaires." } } ] } ] }

Sources (10000 au total)

Effect of dapagliflozin on readmission and loop diuretics use in patients with acute heart failure: a retrospective propensity score-matched cohort study.

The efficacy of dapagliflozin in patients with acute heart failure remains unclear.... To investigate the impact of dapagliflozin (DAPA) on loop diuretics use and 90-day readmission in patients with acute heart failure.... In a retrospective cohort study, patients diagnosed with acute heart failure or chronic heart failure with acute exacerbation admitted to Fuyang People's Hospital from January 2021 to April 2023, this... A total of 399 patients were included, with 206 patients (51.63%) in the DAPA group and 193 patients (48.37%) in the DAPA-Free group. PSM produced 160 pairs. After PSM, there were no statistically sig... DAPA reduced the dose of intravenous loop diuretics. However, it did not improve all-cause readmission for 90 days or readmission for heart failure after discharge....

[The effect of sodium-glucose cotransporter type 2 inhibitors on left ventricular diastolic function: current status and prospects].

Sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) or gliflozins, are a new class of cardiovascular drugs with a proven clinical efficacy and a beneficial effect on prognosis in patients wit...

Empagliflozin's role in early tubular protection for type 2 diabetes patients.

Patients with type 2 diabetes often face early tubular injury, necessitating effective treatment strategies. This study aimed to evaluate the impact of the SGLT2 inhibitor empagliflozin on early tubul... A randomized controlled clinical study comprising 54 patients selected based on specific criteria was conducted. Patients were divided into an intervention group (empagliflozin, n = 27) and a control ... Both groups demonstrated comparable baseline characteristics. Post-treatment, fasting and postprandial blood glucose levels decreased similarly in both groups. The intervention group exhibited better ... Treatment with empagliflozin in type 2 diabetes patients with normoalbuminuria led to a notable decrease in tubular injury biomarkers KIM-1 and NGAL. These findings highlight the potential of SGLT2 in...

Unique Presentation of Asymptomatic Bacteriuria, Vertebral Osteomyelitis, and Iliopsoas Abscess Due to Klebsiella pneumonia in a 73-Year-Old Man with Type 2 Diabetes Mellitus on Empagliflozin.

BACKGROUND Sodium-glucose co-transporter 2 inhibitors (SGLT2), such as empagliflozin, used to treat type 2 diabetes mellitus (DM), can increase the risk of infections, including urinary tract infectio...

Maternal bisphenols exposure and thyroid function in children: a systematic review and meta-analysis.

Evidence from animal experiments and epidemiological studies has reported controversial results about the effects of prenatal bisphenols (BPs) exposure on childhood thyroid function. This study aims t... Correlated studies were systematically searched from PubMed, Web of Science, Medline, Cochrane, and Embase until February 21, 2024. The exposures assessed include bisphenol A (BPA), bisphenol F (BPF),... Eleven cohort studies comprising 5,363 children were included in our meta-analysis. Prenatal bisphenol concentrations were statistically significant related to alterations in thyroid hormones in child... Prenatal bisphenol exposure is linked to alterations in thyroid hormone levels in girls, necessitating enhanced measures to control bisphenol exposure levels during pregnancy for child health protecti... https://inplasy.com, identifier INPLASY202450129....

Effect of empagliflozin on ventricular arrhythmias in patients with type 2 diabetes treated with an implantable cardioverter-defibrillator: the EMPA-ICD trial.

Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure and cardiovascular death with type 2 diabetes; however, their effect on arrhythmias is unclear. T... A total of 150 patients with type 2 diabetes who were treated with an implantable cardioverter-defibrillator or cardiac resynchronization therapy defibrillator (ICD/CRT-D) were randomized to once-dail... In the empagliflozin group, the number of ventricular arrhythmias recorded by ICD/CRT-D decreased by 1.69 during treatment compared to before treatment, while in the placebo group, the number increase... In patients with type 2 diabetes treated with ICD/CRT-D, empagliflozin reduces the number of ventricular arrhythmias compared with placebo. Trial registration jRCTs031180120....

Empagliflozin's role in reducing ventricular repolarization heterogeneity: insights into cardiovascular mortality decline from the EMPATHY-HEART trial.

The incidence of myocardial infarction (MI) and sudden cardiac death (SCD) is significantly higher in individuals with Type 2 Diabetes Mellitus (T2DM) than in the general population. Strategies for th... Participants were adult outpatients with T2DM and CHD who exhibited TWH > 80 µV at baseline. They received a 25 mg daily dose of empagliflozin and were evaluated clinically including electrocardiogram... An initial review of 6,000 medical records pinpointed 800 patients for TWH evaluation. Of these, 412 exhibited TWH above 80 µV, with 97 completing clinical assessments and 90 meeting the criteria for ... The EMPATHY-HEART trial preliminarily suggests that empagliflozin decreases heterogeneity in ventricular repolarization among patients with T2DM and CHD. This reduction in TWH may provide insight into... NCT: 04117763....

A 5:2 Intermittent Fasting Meal Replacement Diet and Glycemic Control for Adults With Diabetes: The EARLY Randomized Clinical Trial.

An intermittent fasting plan consisting of 2 nonconsecutive fasting days and 5 days of habitual intake per week and meal replacement diet (5:2 MR) could provide additional benefits to patients with ty... To evaluate the effect of the 5:2 MR on glycemic control among patients with early type 2 diabetes compared with metformin and empagliflozin.... The EARLY (Exploration of Treatment of Newly Diagnosed Overweight/Obese Type 2 Diabetes Mellitus) study is a randomized, open-label, active parallel-controlled clinical trial conducted between Novembe... Patients were randomly allocated in a 1:1:1 ratio to receive either metformin, empagliflozin, or 5:2 MR. The treatment was 16 weeks, with an 8-week follow-up.... The primary end point was the change in hemoglobin A1c (HbA1c) level from baseline to 16 weeks. Secondary end points included changes in body weight, anthropometric measurements, and biochemical param... Of the 405 randomized participants (265 men [65.4%]; mean [SD] age, 45.5 [11.0] years; mean [SD] body mass index, 29.5 [4.1]; and mean [SD] HbA1c level, 7.9% [0.6%]), 332 completed the 16-week treatme... This randomized clinical trial of Chinese adults with overweight or obesity and with early type 2 diabetes found that 5:2 MR could improve glycemic outcomes and weight loss in the short term compared ... Chinese Clinical Trial Registry Identifier: ChiCTR2000040656....

Is GFR decline induced by SGLT2 inhibitor of clinical importance?

Use of sodium-glucose-cotransporter-2 (SGLT2) inhibitors often causes an initial decline in glomerular filtration rate (GFR). This study addresses the question whether the initial decline of renal fun... We measured GFR (mGFR) and estimated GFR (eGFR) in 65 patients with type 2 diabetes (T2D) at baseline and after 12 weeks of treatment randomized either to a combination of empagliflozin and linaglipti... Both mGFR and eGFR decreased significantly after initiating treatment, but no correlation was found between change in mGFR and change in eGFR in either treatment group (SGLT2 inhibitor based treatment... Our main finding is that after initiating a SGLT2 inhibitor based therapy an exaggerated decline in mGFR was related with improved vascular compliance of large arteries reflecting the pharmacologic ef... clinicaltrials.gov (NCT02752113)....