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Enzymes et coenzymes
Enzymes
Oxidoreductases
NADH, NADPH oxidoreductases
NADH, NADPH oxidoreductases : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Déficience enzymatique
Tests génétiques
Fatigue
Troubles métaboliques
Activité enzymatique
Évaluation fonctionnelle
Anomalies génétiques
Mutations
Symptômes
5
Déficience en NADPH
Infections fréquentes
Troubles neurologiques
Dysfonctionnement enzymatique
Troubles digestifs
Métabolisme énergétique
Prévention
5
Alimentation équilibrée
Nutriments essentiels
Mode de vie sain
Exercice
Bilans de santé
Anomalies enzymatiques
Éducation nutritionnelle
Carences
Traitements
5
Suppléments enzymatiques
Modifications diététiques
Thérapie génique
Déficiences enzymatiques
Médicaments
Modulation enzymatique
Transfusions sanguines
Déficiences
Complications
5
Complications
Troubles métaboliques
Infections
Déficiences enzymatiques
Maladies chroniques
Diabète
Complications cardiovasculaires
Troubles métaboliques
Complications hématologiques
Métabolisme
Facteurs de risque
5
Antécédents familiaux
Maladies métaboliques
Mode de vie sédentaire
Mauvaise alimentation
Maladies génétiques
Prédisposition
Stress oxydatif
Déficiences enzymatiques
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"text": "Des tests enzymatiques et des analyses génétiques peuvent être utilisés pour diagnostiquer."
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{
"@type": "Question",
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"@type": "Question",
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"@type": "Question",
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"position": 8,
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"@type": "Question",
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"position": 9,
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"@type": "Question",
"name": "Des symptômes digestifs peuvent-ils apparaître ?",
"position": 10,
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"text": "Oui, des troubles digestifs peuvent être liés à des anomalies dans le métabolisme énergétique."
}
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"@type": "Question",
"name": "Comment prévenir les déficiences en NADH ?",
"position": 11,
"acceptedAnswer": {
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"text": "Une alimentation équilibrée riche en nutriments essentiels peut aider à prévenir ces déficiences."
}
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"@type": "Question",
"name": "Y a-t-il des habitudes de vie à adopter ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sain incluant exercice et gestion du stress est recommandé."
}
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"@type": "Question",
"name": "Les bilans de santé réguliers sont-ils utiles ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des bilans réguliers peuvent aider à détecter précocement des anomalies enzymatiques."
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{
"@type": "Question",
"name": "Les vaccinations peuvent-elles jouer un rôle ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent prévenir des infections qui aggravent les déficiences."
}
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"@type": "Question",
"name": "L'éducation nutritionnelle est-elle importante ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, comprendre l'importance des nutriments peut aider à prévenir les carences."
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"@type": "Question",
"name": "Quels traitements existent pour les déficiences enzymatiques ?",
"position": 16,
"acceptedAnswer": {
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"text": "Les traitements peuvent inclure des suppléments enzymatiques et des modifications diététiques."
}
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"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 17,
"acceptedAnswer": {
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"text": "Oui, la thérapie génique est explorée pour traiter certaines déficiences enzymatiques."
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"@type": "Question",
"name": "Les médicaments peuvent-ils aider à réguler ces enzymes ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments peuvent aider à moduler l'activité des NADH et NADPH oxydoréductases."
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"@type": "Question",
"name": "Y a-t-il des traitements naturels recommandés ?",
"position": 19,
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"text": "Des antioxydants et des nutriments peuvent soutenir la fonction enzymatique."
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"@type": "Question",
"name": "Les transfusions sanguines sont-elles nécessaires ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Dans certains cas graves, des transfusions peuvent être nécessaires pour corriger des déficiences."
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"@type": "Question",
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"@type": "Question",
"name": "Les infections sont-elles une complication fréquente ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes avec des déficiences enzymatiques sont plus susceptibles aux infections."
}
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"@type": "Question",
"name": "Y a-t-il des risques de maladies chroniques ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déficiences peuvent augmenter le risque de maladies chroniques comme le diabète."
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"@type": "Question",
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"position": 25,
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"@type": "Question",
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"@type": "Question",
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"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les maladies génétiques sont-elles un facteur ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies génétiques prédisposent aux déficiences en NADH et NADPH."
}
},
{
"@type": "Question",
"name": "Le stress oxydatif joue-t-il un rôle ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress oxydatif peut aggraver les déficiences enzymatiques et leurs effets."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
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The purpose of this study was to test the hypothesis that an individualized exercise training target heart rate (HR) based on a maximal graded exercise test (GXT) is associated with greater improvemen...
Chronic Obstructive Pulmonary Disease (COPD) is a disease that is spreading worldwide and is responsible for a huge number of deaths annually. It is characterized by progressive and often irreversible...
Background and Objectives: Muscle blood flow is impeded during resistance exercise contractions, but immediately increases during recovery. The purpose of this study was to determine the impact of bri...
Patients with chronic obstructive pulmonary disease (COPD) have difficulties inhaling as the diaphragm becomes flattened and weakened due to lung hyperinflation. This weakened respiratory function is ...
This study aimed to evaluate the difference in the SCM thickening fraction (SCM TF) of each respiratory phase (end-expiration, resting inspiration, and end-inspiration), as measured using ultrasonogra...
Patients with COPD (n = 44) and age-matched controls (n = 20) underwent US for determination of the SCM TF. Ventilation parameters, including the peak oxygen uptake (peak VO2) and the change in the in...
The SCM was significantly thinner in patients with COPD than in controls at end-expiration. The increase in the SCM TF from end-expiration to end-inspiration in patients with COPD did not differ signi...
The SCM may be thinner in patients with COPD than in controls. The SCM TF may also be associated with exercise tolerance....
What is the central question of this study? Does prescribing exercise intensity using physiological thresholds create a more homogeneous exercise stimulus than using traditional intensity anchors? Wha...
The objective of this study was to determine whether the variability in exercise tolerance and physiological responses is lower when exercise is prescribed relative to physiological thresholds (THR) c...
Patients with multiple sclerosis (MS) experience reduced exercise tolerance that substantially reduces quality of life. The mechanisms underpinning exercise intolerance in MS are not fully clear. This...
Twenty-three patients with MS (13 women) and 20 age-matched and sex-matched healthy controls (13 women) performed a cardiopulmonary exercise test. Muscle fibre type composition, size, succinate dehydr...
Patients with MS had lower maximal oxygen uptake compared with healthy controls (V̇O...
Skeletal muscle oxidative phenotype (mitochondrial complex I and II content, SDH activity) is lower in patients with MS, contributing to reduced exercise tolerance. However, skeletal muscle mitochondr...
Following ST-segment elevation myocardial infarction (STEMI), patients with cardiac dysfunction have limitations in performing physical activity. Right ventricular (RV) function is a determinant in im...
To evaluate the association of RV function with exercise tolerance after a CR program in patients with STEMI....
Retrospective cohort study in patients with STEMI from January to December 2019. They underwent an echocardiographic assessment of RV function before a 16-session CR program. A cardiopulmonary exercis...
A total of 109 patients were included. Of all, 3.7% had global RV dysfunction, 10.1% had radial RV dysfunction, and 11% had longitudinal RV dysfunction. An association between radial or longitudinal R...
RV dysfunction is associated with a lower capacity to exercise; CR programs can be extended or modified in these patients....
The Buffalo Concussion Treadmill Test (BCTT) is a standard assessment of exercise tolerance utilized for exercise prescription following concussion and to inform decisions regarding return to play. On...
Prospective cohort study, pretest/posttest....
A total of 30 participants included 13 women (43.3%), age 23.4 (1.93) years, height 173.56 (10) cm, weight 77.35 (16.3) kg, and 11 (36.7%) with history of concussion. All participants completed a neur...
BCTT: Average percentage of heart rate maximum (%HRmax) = 93.97% (4.8%); average maximum rating of perceived exertion = 18.6 (1.5). Time-based performance in single-task and dual-task conditions signi...
Healthy participants demonstrated improvements across multiple domains of neurocognitive performance following the exercise tolerance testing on the BCTT. Understanding normal responses in neurocognit...
Critical torque (CT) and work done above it ( W ') are key predictors of exercise performance associated with neuromuscular fatigue. The aim of the present study was to understand the role of the meta...
Twelve subjects performed four knee extension time trials (6, 8, 10, and 12 min) using eccentric, isometric, or concentric contractions (3-s on/2-s off at 90°·s -1 or 30°·s -1 ) to modulate the metabo...
Compared with isometric exercise, total impulse (+36% ± 21%; P < 0.001), CT (+27% ± 30%; P < 0.001), and W ' (+67% ± 99%; P < 0.001) were increased during eccentric exercise, whereas total impulse (-2...
The contraction mode influenced both CT and W ', and consequently exercise tolerance, indicating that the metabolic cost of contraction played a key role....
In patients with chronic obstructive pulmonary disease (COPD), the clinical use of the minute ventilation-carbon dioxide production ([Formula: see text]...
We hypothesized that the [Formula: see text]...
Compared with the GOLD I-II group (n = 51), peak [Formula: see text]...
The OUES may be less useful in advanced COPD with exertional hypoxemia. The [Formula: see text]...
