questionsmedicales.fr
Malformations et maladies congénitales, héréditaires et néonatales
Malformations
Malformations du système nerveux
Anomalies du tube neural
Anomalies du tube neural : Questions médicales fréquentes
Termes MeSH sélectionnés :
Angiotensin-Converting Enzyme 2
Diagnostic
5
Anomalies du tube neural
Échographie prénatale
Amniocentèse
Échographie 3D
Grossesse
Diagnostic prénatal
Échographie
Malformations congénitales
Examen physique
Anomalies congénitales
Symptômes
5
Symptômes
Troubles neurologiques
Retard de développement
Difficultés motrices
Cognition
Anomalies du tube neural
Hernie spinale
Malformations crâniennes
Prévention
5
Vaccinations
Santé maternelle
Antécédents familiaux
Risque génétique
Traitements
5
Chirurgie
Anomalies du tube neural
Rééducation physique
Orthophonie
Soutien psychologique
Anomalies congénitales
Complications
5
Infections
Troubles neurologiques
Décès néonatal
Anomalies congénitales
Qualité de vie
Soins constants
Troubles cognitifs
Complications à long terme
Suivi médical
Prévention des complications
Facteurs de risque
5
Facteurs de risque
Diabète
Âge maternel
Risque accru
Médicaments
Antiépileptiques
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Anomalies du tube neural : Questions médicales les plus fréquentes",
"headline": "Anomalies du tube neural : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Anomalies du tube neural : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-06-16",
"dateModified": "2025-03-13",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Anomalies du tube neural"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Malformations du système nerveux",
"url": "https://questionsmedicales.fr/mesh/D009421",
"about": {
"@type": "MedicalCondition",
"name": "Malformations du système nerveux",
"code": {
"@type": "MedicalCode",
"code": "D009421",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Anencéphalie",
"alternateName": "Anencephaly",
"url": "https://questionsmedicales.fr/mesh/D000757",
"about": {
"@type": "MedicalCondition",
"name": "Anencéphalie",
"code": {
"@type": "MedicalCode",
"code": "D000757",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666.680.196"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Malformation d'Arnold-Chiari",
"alternateName": "Arnold-Chiari Malformation",
"url": "https://questionsmedicales.fr/mesh/D001139",
"about": {
"@type": "MedicalCondition",
"name": "Malformation d'Arnold-Chiari",
"code": {
"@type": "MedicalCode",
"code": "D001139",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666.680.291"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Myéloméningocèle",
"alternateName": "Meningomyelocele",
"url": "https://questionsmedicales.fr/mesh/D008591",
"about": {
"@type": "MedicalCondition",
"name": "Myéloméningocèle",
"code": {
"@type": "MedicalCode",
"code": "D008591",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666.680.610"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Pentalogie de Cantrell",
"alternateName": "Pentalogy of Cantrell",
"url": "https://questionsmedicales.fr/mesh/D058502",
"about": {
"@type": "MedicalCondition",
"name": "Pentalogie de Cantrell",
"code": {
"@type": "MedicalCode",
"code": "D058502",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666.680.705"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Dysraphie spinale",
"alternateName": "Spinal Dysraphism",
"url": "https://questionsmedicales.fr/mesh/D016135",
"about": {
"@type": "MedicalCondition",
"name": "Dysraphie spinale",
"code": {
"@type": "MedicalCode",
"code": "D016135",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666.680.800"
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Spina bifida cystica",
"alternateName": "Spina Bifida Cystica",
"url": "https://questionsmedicales.fr/mesh/D016137",
"about": {
"@type": "MedicalCondition",
"name": "Spina bifida cystica",
"code": {
"@type": "MedicalCode",
"code": "D016137",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666.680.800.730"
}
}
},
{
"@type": "MedicalWebPage",
"name": "Spina bifida occulta",
"alternateName": "Spina Bifida Occulta",
"url": "https://questionsmedicales.fr/mesh/D016136",
"about": {
"@type": "MedicalCondition",
"name": "Spina bifida occulta",
"code": {
"@type": "MedicalCode",
"code": "D016136",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C16.131.666.680.800.750"
}
}
}
]
}
],
"about": {
"@type": "MedicalCondition",
"name": "Anomalies du tube neural",
"alternateName": "Neural Tube Defects",
"code": {
"@type": "MedicalCode",
"code": "D009436",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Richard H Finnell",
"url": "https://questionsmedicales.fr/author/Richard%20H%20Finnell",
"affiliation": {
"@type": "Organization",
"name": "Department of Molecular and Human Genetics and Medicine, Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, United States."
}
},
{
"@type": "Person",
"name": "Zhiwen Li",
"url": "https://questionsmedicales.fr/author/Zhiwen%20Li",
"affiliation": {
"@type": "Organization",
"name": "National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China."
}
},
{
"@type": "Person",
"name": "Lei Jin",
"url": "https://questionsmedicales.fr/author/Lei%20Jin",
"affiliation": {
"@type": "Organization",
"name": "National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China."
}
},
{
"@type": "Person",
"name": "Linlin Wang",
"url": "https://questionsmedicales.fr/author/Linlin%20Wang",
"affiliation": {
"@type": "Organization",
"name": "National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China."
}
},
{
"@type": "Person",
"name": "Aiguo Ren",
"url": "https://questionsmedicales.fr/author/Aiguo%20Ren",
"affiliation": {
"@type": "Organization",
"name": "National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Angiotensin-converting enzyme 2-at the heart of the COVID-19 pandemic.",
"datePublished": "2023-02-02",
"url": "https://questionsmedicales.fr/article/36787743",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.cell.2023.01.039"
}
},
{
"@type": "ScholarlyArticle",
"name": "Effects of spike proteins on angiotensin converting enzyme 2 (ACE2).",
"datePublished": "2023-09-27",
"url": "https://questionsmedicales.fr/article/37769892",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.abb.2023.109769"
}
},
{
"@type": "ScholarlyArticle",
"name": "Effect of renin angiotensin blockers on angiotensin converting enzyme 2 level in cardiovascular patients.",
"datePublished": "2023-04-14",
"url": "https://questionsmedicales.fr/article/37060024",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s40360-023-00667-w"
}
},
{
"@type": "ScholarlyArticle",
"name": "Serum levels of angiotensin-converting enzyme 2 in children with Kawasaki disease.",
"datePublished": "2022-11-07",
"url": "https://questionsmedicales.fr/article/36344782",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s10238-022-00933-x"
}
},
{
"@type": "ScholarlyArticle",
"name": "Angiotensin-Converting Enzyme 2 (ACE2) Gene Polymorphism in Patients with Type 2 Diabetes (",
"datePublished": "2022-12-31",
"url": "https://questionsmedicales.fr/article/37274884",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.22092/ARI.2022.358736.2294"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Malformations et maladies congénitales, héréditaires et néonatales",
"item": "https://questionsmedicales.fr/mesh/D009358"
},
{
"@type": "ListItem",
"position": 3,
"name": "Malformations",
"item": "https://questionsmedicales.fr/mesh/D000013"
},
{
"@type": "ListItem",
"position": 4,
"name": "Malformations du système nerveux",
"item": "https://questionsmedicales.fr/mesh/D009421"
},
{
"@type": "ListItem",
"position": 5,
"name": "Anomalies du tube neural",
"item": "https://questionsmedicales.fr/mesh/D009436"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Anomalies du tube neural - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Anomalies du tube neural",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-14",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Anomalies du tube neural",
"description": "Comment diagnostique-t-on une anomalie du tube neural ?\nQuels examens sont utilisés pour confirmer le diagnostic ?\nÀ quel moment le diagnostic est-il généralement posé ?\nQuels signes échographiques indiquent une anomalie ?\nPeut-on détecter ces anomalies après la naissance ?",
"url": "https://questionsmedicales.fr/mesh/D009436?mesh_terms=Angiotensin-Converting+Enzyme+2#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Anomalies du tube neural",
"description": "Quels sont les symptômes d'une anomalie du tube neural ?\nLes anomalies du tube neural causent-elles des douleurs ?\nComment se manifestent les anomalies après la naissance ?\nLes anomalies du tube neural affectent-elles la cognition ?\nY a-t-il des signes visibles à la naissance ?",
"url": "https://questionsmedicales.fr/mesh/D009436?mesh_terms=Angiotensin-Converting+Enzyme+2#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Anomalies du tube neural",
"description": "Comment prévenir les anomalies du tube neural ?\nQuel est le dosage recommandé d'acide folique ?\nY a-t-il d'autres mesures préventives ?\nLes vaccinations influencent-elles le risque ?\nLes antécédents familiaux augmentent-ils le risque ?",
"url": "https://questionsmedicales.fr/mesh/D009436?mesh_terms=Angiotensin-Converting+Enzyme+2#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Anomalies du tube neural",
"description": "Quels traitements sont disponibles pour ces anomalies ?\nLa chirurgie est-elle toujours nécessaire ?\nQuels types de rééducation sont recommandés ?\nY a-t-il des traitements médicamenteux ?\nComment le soutien psychologique aide-t-il ?",
"url": "https://questionsmedicales.fr/mesh/D009436?mesh_terms=Angiotensin-Converting+Enzyme+2#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Anomalies du tube neural",
"description": "Quelles complications peuvent survenir ?\nLes anomalies du tube neural peuvent-elles entraîner des décès ?\nComment les complications affectent-elles la qualité de vie ?\nY a-t-il des complications à long terme ?\nLes complications sont-elles évitables ?",
"url": "https://questionsmedicales.fr/mesh/D009436?mesh_terms=Angiotensin-Converting+Enzyme+2#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Anomalies du tube neural",
"description": "Quels sont les principaux facteurs de risque ?\nL'âge maternel influence-t-il le risque ?\nLes médicaments peuvent-ils augmenter le risque ?\nLe poids maternel joue-t-il un rôle ?\nLes infections pendant la grossesse sont-elles un risque ?",
"url": "https://questionsmedicales.fr/mesh/D009436?mesh_terms=Angiotensin-Converting+Enzyme+2#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostique-t-on une anomalie du tube neural ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic se fait par échographie prénatale et tests génétiques."
}
},
{
"@type": "Question",
"name": "Quels examens sont utilisés pour confirmer le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'amniocentèse et l'échographie 3D peuvent confirmer les anomalies."
}
},
{
"@type": "Question",
"name": "À quel moment le diagnostic est-il généralement posé ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic est souvent posé entre la 12e et la 20e semaine de grossesse."
}
},
{
"@type": "Question",
"name": "Quels signes échographiques indiquent une anomalie ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme l'absence de boîte crânienne ou des malformations vertébrales."
}
},
{
"@type": "Question",
"name": "Peut-on détecter ces anomalies après la naissance ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies peuvent être détectées par examen physique après la naissance."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une anomalie du tube neural ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des problèmes neurologiques, des malformations crâniennes et des troubles moteurs."
}
},
{
"@type": "Question",
"name": "Les anomalies du tube neural causent-elles des douleurs ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les douleurs ne sont pas typiques, mais des complications peuvent entraîner des douleurs."
}
},
{
"@type": "Question",
"name": "Comment se manifestent les anomalies après la naissance ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent se manifester par des difficultés motrices et des retards de développement."
}
},
{
"@type": "Question",
"name": "Les anomalies du tube neural affectent-elles la cognition ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent affecter la cognition, selon la gravité et le type d'anomalie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes visibles à la naissance ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des signes comme une hernie spinale ou des malformations crâniennes peuvent être visibles."
}
},
{
"@type": "Question",
"name": "Comment prévenir les anomalies du tube neural ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prise d'acide folique avant et pendant la grossesse réduit le risque."
}
},
{
"@type": "Question",
"name": "Quel est le dosage recommandé d'acide folique ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un dosage de 400 à 800 microgrammes par jour est recommandé pour les femmes enceintes."
}
},
{
"@type": "Question",
"name": "Y a-t-il d'autres mesures préventives ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter l'alcool et le tabac, et gérer les maladies chroniques sont également importants."
}
},
{
"@type": "Question",
"name": "Les vaccinations influencent-elles le risque ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations sont recommandées pour protéger la santé maternelle et fœtale."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux augmentent-ils le risque ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux d'anomalies du tube neural peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour ces anomalies ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent la chirurgie, la rééducation et le soutien psychologique."
}
},
{
"@type": "Question",
"name": "La chirurgie est-elle toujours nécessaire ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, la nécessité de la chirurgie dépend de la gravité de l'anomalie."
}
},
{
"@type": "Question",
"name": "Quels types de rééducation sont recommandés ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La rééducation physique et l'orthophonie sont souvent recommandées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements médicamenteux ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments peuvent être prescrits pour gérer les symptômes associés."
}
},
{
"@type": "Question",
"name": "Comment le soutien psychologique aide-t-il ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il aide les familles à faire face aux défis émotionnels et pratiques des anomalies."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections, des troubles neurologiques et des problèmes de mobilité."
}
},
{
"@type": "Question",
"name": "Les anomalies du tube neural peuvent-elles entraîner des décès ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies graves peuvent entraîner des décès néonatals."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent limiter les activités quotidiennes et nécessiter des soins constants."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications à long terme peuvent inclure des troubles cognitifs et moteurs."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles évitables ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être évitées par un suivi médical approprié."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, le diabète et la carence en acide folique."
}
},
{
"@type": "Question",
"name": "L'âge maternel influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes de plus de 35 ans ont un risque accru d'anomalies du tube neural."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils augmenter le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments, comme les antiépileptiques, peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Le poids maternel joue-t-il un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité maternelle est un facteur de risque pour les anomalies du tube neural."
}
},
{
"@type": "Question",
"name": "Les infections pendant la grossesse sont-elles un risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections, comme la rubéole, peuvent augmenter le risque d'anomalies."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 13/03/2025
Contenu vérifié selon les dernières recommandations médicales
8 publications dans cette catégorie
Affiliations :
Department of Molecular and Human Genetics and Medicine, Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, United States.
Department of Molecular and Cellular Biology, Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, United States.
7 publications dans cette catégorie
Affiliations :
National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China.
5 publications dans cette catégorie
Affiliations :
National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China.
Publications dans "Anomalies du tube neural" :
5 publications dans cette catégorie
Affiliations :
National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China.
Publications dans "Anomalies du tube neural" :
5 publications dans cette catégorie
Affiliations :
National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China.
Publications dans "Anomalies du tube neural" :
5 publications dans cette catégorie
Affiliations :
Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Publications dans "Anomalies du tube neural" :
3 publications dans cette catégorie
Affiliations :
Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Department of Obstetrics and Gynecology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Publications dans "Anomalies du tube neural" :
3 publications dans cette catégorie
Affiliations :
Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Publications dans "Anomalies du tube neural" :
3 publications dans cette catégorie
Affiliations :
Department of Social Medicine and Health Education, School of Public Health, Peking University, Beijing, China.
Publications dans "Anomalies du tube neural" :
3 publications dans cette catégorie
Affiliations :
Beijing Municipal Key Laboratory of Child Development and Nutriomics, Translational Medicine Laboratory, Capital Institute of Pediatrics, Beijing 100020, China.
Publications dans "Anomalies du tube neural" :
3 publications dans cette catégorie
Affiliations :
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.
Publications dans "Anomalies du tube neural" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Key Laboratory for Cellular Physiology of Ministry of Education, Shanxi Medical University, Taiyuan, Shanxi, China (mainland).
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
National Health Commission Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Institute of Reproductive and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China.
Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Department of Neurosurgery, Macquarie University Hospital, Sydney, Australia.
Department of Paediatric Neurosurgery, Sydney Children's Hospital Randwick, Sydney, Australia.
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
Department of Paediatric Neurosurgery, Great Ormond Street Hospital for Children, NHS Trust, London, UK.
Department of Paediatric Neurosurgery, University of California, Davis, CA, USA.
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
Department of Obstetrics, Gynecology and Reproductive Sciences, UT Health Science Center at Houston, 6410 Fannin Street, Suite 210, Houston, TX 77030, USA.
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
Department of Pediatric Surgery, UT Health Science Center at Houston, 6410 Fannin Street, Suite 950, Houston, TX 77030, USA.
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
Beijing Municipal Key Laboratory of Child Development and Nutriomics, Translational Medicine Laboratory, Capital Institute of Pediatrics, Beijing 100020, China.
Publications dans "Anomalies du tube neural" :
2 publications dans cette catégorie
Affiliations :
Molecular Cellular Developmental Biology, University of Colorado, Boulder, Colorado, USA.
Publications dans "Anomalies du tube neural" :
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the COVID-19 pandemic, it has become one of the most therapeutically targeted human molecules in biomedicine. ACE2 serv...
The Coronavirus Disease 2019 (COVID-19) pandemic was caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which enters host cells through interactions of its spike protein to Angiot...
Renin-angiotensin-aldosterone system (RAAS) is hypothesized to be in the center of COVID pathophysiology as the angiotensin converting enzyme 2 (ACE2) represents the main entrance of the virus, thus t...
A total of 40 healthy controls and 60 Egyptian patients suffering from chronic cardiovascular diseases were enrolled in this study. Patients were divided into 40 patients treated with ACEIs and 20 pat...
Assessment of serum ACE2 level in different groups showed a significant difference between ACEIs and healthy groups and ACEIs and ARBs group, while there was no difference between ARBs and healthy. Mu...
ACE2 levels varied between ACEIs and ARBs. It tends to be lower in ACEIs group and there is a strong positive association between ACE2 level and the female sex. This needs to be considered in Future s...
Retrospectively registered ClinicalTrials.gov ID: NCT05418361 (June 2022)....
Kawasaki disease (KD) has replaced rheumatic fever as the main cause of acquired heart disease in Japanese, American, and Chinese children. Polymorphisms in angiotensin-converting enzyme may be associ...
The increased levels of blood glucose associated with genetic and/or environmental risk factors have been known as Type 2 diabetes mellitus (T2D). T2D is categorized as a dangerous clinical syndrome f...
Rapid and cost-effective diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are a critical and valuable weapon for the coronavirus disease 2019 (COVID-19) pandemic respo...
In order to prevent COVID-19 from progressing, angiotensin-converting enzyme 2 (ACE2) binds to SARS-CoV-2 and prevents the virus from entering target cells. Several studies have found a correlation be...
We conducted a systematic review using PubMed, Embase, Cochrane Library, Scopus, Science Direct and Web of Science databases. The odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. ...
It was concluded that the ACE2 G8790A polymorphism was not associated with COVID-19 based on the data collected. Moreover, subgroup analyses stratified based on race proved that the ACE2 G allele show...
The findings indicated that the G allele of ACE2 G8790A was related to an enhanced risk of COVID-19 severity in Asians. One possible reason is that ACE2 G allele was associated with a COVID-19 cytokin...
Systemic sclerosis (SSc) is a disease with cardiovascular impairment and polymorphisms of the gene coding of angiotensin-converting-enzyme 2 (ACE2) may account for its development. Three single nucleo...
Genomic DNA was isolated from whole blood. Restriction-fragment-length polymorphism was used for genotyping of rs1978124, while detection of rs879922 and rs2285666 was based on TaqMan SNP Genotyping A...
81 SSc patients (60 women, 21 men) were enrolled. Allele C of rs879922 polymorphism was associated with significantly greater risk for development of AH (OR=2.5, p=0.018), but less frequent joint invo...
Polymorphisms of ACE2 may account for the development of AH and CVS disorders in SSc patients. Strong tendencies to more frequent occurrence of disease specific characteristics distinct to macrovascul...
The quick and advancing prevalence of the new coronavirus SARS-CoV-2 produced a global crisis surge with a profound impact on human health and worldwide economic constancy. The virus is known as one s...
The Angiotensin-Converting Enzyme 2 (ACE2) is the main receptor of the SARS-CoV-2. There is contradictory evidence on how the exposure to nicotine may module the concentration of soluble ACE2 (sACE2)....
Pooled analysis performed with data retrieved from two studies (n = 634 and n = 302). Geometric mean (GM) concentrations of sACE2, both total and relative to the total amount of protein in the sample,...
We observed a significant increase of 0.108‰ and 0.087 ng/μl in the relative and absolute salivary sACE2 GM concentrations, respectively, between the lowest and highest nicotine levels. Similar result...
Salivary nicotine concentration seems to be limitedly associated with the concentration of sACE2....