Trends in extracellular matrix biology.
Extracellular matrixes (ECMs) are intricate 3-dimensional macromolecular networks of unique architectures with regulatory roles in cell morphology and functionality. As a dynamic native biomaterial, E...
Activité de type insulinique non suppressible : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer l'activité insulinique non suppressible ?
Des tests sanguins mesurant les niveaux d'insuline et de glucose sont effectués.
#2
Quels tests sont utilisés pour évaluer cette condition ?
Le test de tolérance au glucose et les dosages d'insuline sont courants.
#3
Quels signes cliniques indiquent cette activité ?
Des symptômes comme l'hyperglycémie persistante peuvent être observés.
#4
L'imagerie est-elle utile pour le diagnostic ?
L'imagerie n'est généralement pas utilisée pour cette condition spécifique.
#5
Peut-on utiliser des biomarqueurs pour le diagnostic ?
Oui, des biomarqueurs comme le peptide C peuvent aider à évaluer l'insulinémie.
Symptômes 5
#1
Quels sont les symptômes courants de cette condition ?
Les symptômes incluent fatigue, soif excessive et besoin fréquent d'uriner.
#2
L'hypoglycémie est-elle un symptôme possible ?
Oui, des épisodes d'hypoglycémie peuvent survenir malgré une insulinémie élevée.
#3
Y a-t-il des symptômes liés à la prise de poids ?
Oui, une prise de poids inexpliquée peut être un symptôme associé.
#4
Les troubles de la vision sont-ils possibles ?
Oui, des troubles visuels peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Des symptômes cutanés peuvent-ils apparaître ?
Oui, des infections cutanées fréquentes peuvent être un signe d'insulinorésistance.
Prévention 5
#1
Comment prévenir l'activité insulinique non suppressible ?
Maintenir un poids santé et adopter un mode de vie actif sont essentiels.
#2
L'alimentation joue-t-elle un rôle préventif ?
Oui, une alimentation équilibrée peut réduire le risque de résistance à l'insuline.
#3
Le dépistage précoce est-il important ?
Oui, le dépistage régulier peut aider à identifier les problèmes tôt.
#4
Le stress influence-t-il cette condition ?
Oui, le stress peut aggraver la résistance à l'insuline et les symptômes.
#5
Les habitudes de sommeil affectent-elles la prévention ?
Oui, un sommeil de qualité est crucial pour la régulation de l'insuline.
Traitements 5
#1
Quels traitements sont disponibles pour cette condition ?
Les traitements incluent des médicaments antidiabétiques et des modifications du mode de vie.
#2
L'insuline est-elle utilisée dans le traitement ?
Oui, l'insuline peut être administrée pour contrôler les niveaux de glucose.
#3
Les changements alimentaires sont-ils recommandés ?
Oui, un régime équilibré et pauvre en glucides est souvent conseillé.
#4
La thérapie physique peut-elle aider ?
Oui, l'exercice régulier peut améliorer la sensibilité à l'insuline.
#5
Des traitements alternatifs existent-ils ?
Certaines approches comme la médecine complémentaire peuvent être explorées.
Complications 5
#1
Quelles complications peuvent survenir ?
Des complications comme le diabète de type 2 et des maladies cardiovasculaires peuvent se développer.
#2
L'insulinorésistance peut-elle entraîner des complications ?
Oui, l'insulinorésistance est liée à des complications métaboliques graves.
#3
Des problèmes rénaux peuvent-ils se développer ?
Oui, des maladies rénales chroniques peuvent être une complication de cette condition.
#4
Les troubles neurologiques sont-ils possibles ?
Oui, des neuropathies peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Y a-t-il un risque accru de maladies cardiaques ?
Oui, le risque de maladies cardiaques est significativement augmenté.
Facteurs de risque 5
#1
Quels sont les principaux facteurs de risque ?
L'obésité, le manque d'exercice et des antécédents familiaux sont des facteurs clés.
#2
L'âge influence-t-il le risque ?
Oui, le risque augmente avec l'âge, surtout après 45 ans.
#3
Le tabagisme est-il un facteur de risque ?
Oui, le tabagisme est associé à une augmentation de la résistance à l'insuline.
#4
Les antécédents médicaux jouent-ils un rôle ?
Oui, des antécédents de diabète gestationnel augmentent le risque futur.
#5
Le stress chronique est-il un facteur de risque ?
Oui, le stress chronique peut contribuer à l'insulinorésistance.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 31/03/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Jie Li
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Xiao-Chen Bai
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
- Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Eunhee Choi
4 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA. EC3477@cumc.columbia.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Catherine Hall
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Jiayi Wu
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Junhee Park
2 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Christopher T V Swain
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Ann E Drummond
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Roger L Milne
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Dallas R English
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Kristy A Brown
2 publications dans cette catégorie
Affiliations :
- Department of Medicine, Weill Cornell Medicine, New York, New York.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tina L Skinner
2 publications dans cette catégorie
Affiliations :
- The University of Queensland, School of Human Movement and Nutrition Sciences, St. Lucia, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Eline H van Roekel
2 publications dans cette catégorie
Affiliations :
- Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Melissa M Moore
2 publications dans cette catégorie
Affiliations :
- Medical Oncology, St. Vincent's Hospital, Melbourne, Australia.
- Department of Medicine, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tom R Gaunt
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Richard M Martin
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
- IHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Sarah J Lewis
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Brigid M Lynch
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Physical Activity Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Carlie Delaine
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Briony E Forbes
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Sources (10000 au total)
Cell-extracellular matrix mechanotransduction in 3D.
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours, including differentiation, migration and proliferation, through mechanotransduction. Studies of cell-ECM mech...
Extracellular Matrix and Cancer: An Intricate Affair.
In complex multicellular eukaryotes, the extracellular matrix (ECM) is an essential component of the organism, not only providing structure to the tissues, but also granting cellular cooperation throu...
The Role of Extracellular Matrix in Wound Healing.
Extracellular matrix communicates with surrounding cells to maintain skin homeostasis and modulate multiple cellular processes including wound healing.... To elucidate the dynamic composition and potential roles of extracellular matrix in normal skin, wound healing process, and abnormal skin scarring.... Literature review was performed to identify relevant publications pertaining to the extracellular matrix deposition in normal skin and wound healing process, as well as in abnormal scars.... A summary of the matrix components in normal skin is presented. Their primary roles in hemostasis, inflammation, proliferation, and remodeling phases of wound healing are briefly discussed. Identifica... Abnormal scarring remains a challenging condition with unmet satisfactory treatments. Illumination of extracellular matrix composition and functions in wound healing process will allow for the develop...
The extracellular matrix and perineuronal nets in memory.
All components of the CNS are surrounded by a diffuse extracellular matrix (ECM) containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans (HSPGs), hyaluronan, various glyc...
Lung extracellular matrix modulates KRT5
Aberrant expansion of KRT5...
Extracellular matrix as a driver for intratumoral heterogeneity.
The architecture of an organ is built through interactions between its native cells and its connective tissue consisting of stromal cells and the extracellular matrix (ECM). Upon transformation throug...
The engineering and application of extracellular matrix hydrogels: a review.
This review provides an overview of the engineering and application of extracellular matrix (ECM) hydrogels. ECM hydrogels are attractive materials for tissue engineering and regenerative medicine due...
Extracellular Matrix Regulation in Physiology and in Brain Disease.
The extracellular matrix (ECM) surrounds cells in the brain, providing structural and functional support. Emerging studies demonstrate that the ECM plays important roles during development, in the hea...
Cartilage extracellular matrix-derived matrikines in osteoarthritis.
Osteoarthritis (OA) is among the most frequent diseases of the musculoskeletal system. Degradation of cartilage extracellular matrix (ECM) is a hallmark of OA. During the degradation process, intact/f...