Acquisition d'organes et de tissus : Questions médicales fréquentes
Nom anglais: Tissue and Organ Procurement
Descriptor UI:D009927
Tree Number:N02.421.911
Termes MeSH sélectionnés :
Randomized Controlled Trials as Topic
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"description": "Comment évaluer la nécessité d'une transplantation ?\nQuels tests sont utilisés pour le don d'organes ?\nComment déterminer la compatibilité des donneurs ?\nQuels critères excluent un donneur potentiel ?\nComment évaluer la fonction d'un organe avant le don ?",
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"@type": "Question",
"name": "Comment évaluer la nécessité d'une transplantation ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'évaluation inclut des tests médicaux, des antécédents et des examens physiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour le don d'organes ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins, d'imagerie et de compatibilité tissulaire sont effectués."
}
},
{
"@type": "Question",
"name": "Comment déterminer la compatibilité des donneurs ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "La compatibilité est évaluée par des tests HLA et des groupes sanguins."
}
},
{
"@type": "Question",
"name": "Quels critères excluent un donneur potentiel ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies infectieuses, des cancers ou des antécédents médicaux graves peuvent exclure."
}
},
{
"@type": "Question",
"name": "Comment évaluer la fonction d'un organe avant le don ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de fonction hépatique, rénale ou cardiaque sont réalisés pour évaluer l'organe."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent un besoin d'organe ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fatigue extrême, douleurs, défaillance d'organe et symptômes d'insuffisance."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une réaction au rejet ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Symptômes incluent fièvre, douleur, gonflement et dysfonction de l'organe transplanté."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'infection post-transplantation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre, frissons, rougeur et douleur au site de la transplantation sont fréquents."
}
},
{
"@type": "Question",
"name": "Quels signes d'une mauvaise fonction rénale ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oligurie, œdème, hypertension et fatigue peuvent indiquer une défaillance rénale."
}
},
{
"@type": "Question",
"name": "Comment identifier une complication pulmonaire ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Toux persistante, essoufflement et douleur thoracique peuvent signaler une complication."
}
},
{
"@type": "Question",
"name": "Comment promouvoir le don d'organes ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Sensibilisation, éducation et campagnes d'information encouragent le don d'organes."
}
},
{
"@type": "Question",
"name": "Quelles sont les mesures de sécurité pour les donneurs ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des évaluations médicales rigoureuses et des protocoles de sécurité sont mis en place."
}
},
{
"@type": "Question",
"name": "Comment éviter les infections chez les receveurs ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Hygiène rigoureuse, vaccinations et suivi médical régulier aident à prévenir les infections."
}
},
{
"@type": "Question",
"name": "Quelles sont les recommandations pour les receveurs ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Suivre les prescriptions, éviter les infections et assister aux rendez-vous médicaux."
}
},
{
"@type": "Question",
"name": "Comment sensibiliser à l'importance du don ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des campagnes médiatiques et des témoignages de receveurs peuvent sensibiliser le public."
}
},
{
"@type": "Question",
"name": "Quels traitements sont nécessaires après une transplantation ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Immunosuppresseurs, suivi médical régulier et gestion des effets secondaires sont essentiels."
}
},
{
"@type": "Question",
"name": "Comment prévenir le rejet d'organe ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'utilisation d'immunosuppresseurs et un suivi régulier aident à prévenir le rejet."
}
},
{
"@type": "Question",
"name": "Quels sont les traitements pour les complications ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications peuvent nécessiter des médicaments, des interventions chirurgicales ou des soins intensifs."
}
},
{
"@type": "Question",
"name": "Comment gérer les effets secondaires des médicaments ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi régulier et des ajustements de dosage aident à gérer les effets secondaires."
}
},
{
"@type": "Question",
"name": "Quels sont les traitements pour les infections post-transplantation ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Antibiotiques et antiviraux sont souvent utilisés pour traiter les infections."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles après une transplantation ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Rejet, infections, complications vasculaires et problèmes de fonction de l'organe transplanté."
}
},
{
"@type": "Question",
"name": "Comment gérer le rejet aigu ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le rejet aigu nécessite souvent des ajustements de médicaments immunosuppresseurs."
}
},
{
"@type": "Question",
"name": "Quels sont les signes d'une infection grave ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre élevée, détérioration rapide de l'état général et symptômes respiratoires sévères."
}
},
{
"@type": "Question",
"name": "Quelles complications cardiovasculaires peuvent survenir ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les receveurs peuvent développer une hypertension, une athérosclérose ou des troubles du rythme."
}
},
{
"@type": "Question",
"name": "Comment prévenir les complications à long terme ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi régulier, une bonne observance des traitements et un mode de vie sain sont cruciaux."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le besoin de transplantation ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maladies chroniques, accidents, infections graves et cancers augmentent le besoin."
}
},
{
"@type": "Question",
"name": "Comment l'âge influence-t-il le don d'organes ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge avancé peut affecter la qualité des organes et la décision de don."
}
},
{
"@type": "Question",
"name": "Quels comportements augmentent les risques de maladies ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Tabagisme, alcoolisme, obésité et sédentarité augmentent les risques de maladies nécessitant un don."
}
},
{
"@type": "Question",
"name": "Comment les antécédents familiaux influencent-ils le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antécédents familiaux de maladies héréditaires peuvent augmenter le risque de défaillance d'organe."
}
},
{
"@type": "Question",
"name": "Quels facteurs socio-économiques influencent le don ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'accès aux soins, l'éducation et la sensibilisation peuvent influencer les taux de don."
}
}
]
}
]
}
To examine the effects of a sport-based exercise therapy program combined with usual care (sET+UC) compared with usual care alone (UC) on health-related quality of life, upper limb motor control, func...
Single-blind, parallel-group, randomized controlled trial....
Rehabilitation center....
Twenty-three adults with ABI (82.6% stroke; 17 males; mean age of 59.6±10.3 yr) INTERVENTION: Participants received either sET+UC (n=11) or UC (n=12). The sET+UC group received sixteen 60-minute sessi...
Primary outcome measures were health-related quality of life (Short Form-36, SF-36) and upper limb motor control (Fugl Meyer-Upper Extremity; FM-UE), while the secondary included functional capacity (...
Significant differences were found in all outcome analyses at post-intervention when comparing between groups. The sET+UC group showed significant improvements in both the physical (p=.027, r=.46) and...
This study shows that a sport-based exercise therapy program combined with usual care can effectively improve all the aforementioned outcomes measures in ABI population. Further research with larger s...
In addition to attention and hyperactivity problems, children with attention deficit hyperactivity disorder (ADHD) have poorer organizational skills needed to manage time and materials. This study exa...
This was a prospective, randomized controlled trial. Between September 2023 and January 2024, 70 children with a diagnosis of ADHD and at least one domain of executive dysfunction (EF) were divided in...
The mean age of the children was 8.33 ± 1.62 years. A total of 66 children completed the intervention and follow-up, 32 in the conventional group and 34 in the OST group. There were no differences bet...
OST can further improve organizational skills in daily life in children with ADHD while improving core symptoms of attention deficit in addition to conventional treatment. The effect of OST on BRIEF i...
The randomized controlled trial registration number was ChiCTR2300075744....
Vital pulp therapy (VPT) is recommended as an alternative treatment to root canal therapy (RCT) for management of teeth with carious pulp exposure. This randomized clinical trial aimed to compare the ...
A total of 160 mature molar teeth with IP were randomly divided into two treatment groups. The FP group (test group) was treated with FP using iRoot BP Plus by an endodontist, the RCT group (control g...
FP and RCT had comparable success rates (Clinical, 97.3% vs. 98.6%; radiographic, 93.3% vs. 94.6%) (P > 0.05). Pain levels decreased over time from day 1 to day 7 postoperative in both groups, and the...
FP could be an appropriate alternative treatment for management of mature teeth with IP in short follow-up....
The trial was registered in Chinese Clinical Trial Registry (ChiCTR2200063380 at 05/09/2022)....
Managing postoperative setting, regarding pain and anxiety after cesarean delivery is crucial for the mother's recovery, her emotional well-being, mother-infant bonding and initiating breastfeeding. A...
This was a monocentric randomized controlled double-blind trial conducted over a period of five months during 2023. A hundred women undergoing c-sections under spinal anesthesia were enrolled and rand...
A total of 100 women were included (50 women in each group aromatherapy and the placebo group). The two groups were comparable regarding baseline characteristics and pre-intervention parameters with n...
Aromatherapy using Lavender essential oil is effective in reducing pain and anxiety after cesarean delivery without adverse effects....
Zinc deficiency is highly prevalent in HD patients. On the other hand, it remains unknown about the role of zinc in their nutritional status....
We conducted an open-label randomized controlled trial. We investigated (i) the relationship between serum zinc levels and body composition and (ii) the effects of zinc supplementation on the composit...
Serum zinc levels were significantly correlated with body fat weight (p < 0.01), but not with nonfat tissue weight. Multiple regression analyses demonstrated that serum zinc levels were a significant ...
Our findings indicate that zinc deficiency plays an important role in fat metabolism in HD patients with its deficiency....
The aim of this systematic review and meta-analysis was to assess whether earlier discharge from hospital after cesarean delivery (CD) affects the rate of maternal readmission....
The research was conducted using PubMed, Embase, Web of Sciences, Scopus, ClinicalTrials.gov and the Cochrane Central Register of Controlled Trials as electronic databases, from the inception of each ...
Selection criteria included only RCTs comparing the effect of earlier vs later hospital discharge after CD....
The primary outcome was the rate of maternal readmission. The summary measures were reported as relative risk (RR) or as mean difference (MD) with 95% confidence intervals (CI) using the random effect...
Seven RCTs including 4,267 individuals, of which 2,125 (49.8%) randomized in the early discharge and 2,142 (50.2%) in the late discharge group were included. There was no difference between the two gr...
There is no increase in the rate of maternal readmission following early hospital discharge at 24-28 hours as opposed to later hospital discharge after a CD. The rates of neonatal readmission and neon...
To reveal the evolution of pain management strategies following mandibular third molar (M3M) exodontia, examine the geographic contribution of research, and explore future developments through a bibli...
A comprehensive search was conducted in various leading databases. Data on bibliometrics, participant demographics, and agent regimens were extracted for eligible studies. Descriptive bibliometrics, c...
A total of 173 randomized control trials from 2004 to 2024 were included. The number of publications showed a consistent upward trend since 2007. Brazil exhibited the most publications and citations. ...
This study revealed information on the research outputs, distribution, and future developments of analgesic agents following M3M exodontia. Brazil exhibited the highest level of productivity and recor...
The bibliometric analysis offers insights into the field of pain management following mandibular 3rd molar exodontia and how it has evolved. Tramadol and piroxicam have become research hotspots in rec...
The rise in internet addiction, including web-based gaming and social networking services, is a serious concern. Even with access to medical institutions and counseling services, individuals with inte...
This study was a pilot randomized controlled trial to test the feasibility of remote cognitive behavioral therapy via videoconferencing for parents of adolescents with internet addiction....
A total of 13 parents of adolescents aged 12-20 years with internet addiction were recruited and randomly assigned to either 12 sessions of the videoconference-delivered cognitive behavioral therapy (...
As the primary outcome, the mean total Internet Addiction Test score decreased from 67.7 (SD 18.3; 6/13, 46%) at week 0 to 56.2 (SD 25.1; 5/9, 56%) at week 13 in the vCBT group, compared to an increas...
This study suggested the practical feasibility of vCBT for parents of adolescents with internet addiction. Further large-scale, multicenter randomized controlled trials are necessary to examine the ef...
UMIN Clinical Trials Registry UMIN000032483; https://tinyurl.com/yuhen6c9....
Acellular dermal matrix (ADM) is pivotal in breast surgery, yet the statistical robustness of surgical outcomes remains underexplored. This study employs the fragility index (FI), reverse fragility in...
Randomized controlled trials (RCTs) (2013-present) with dichotomous outcomes were sourced from PubMed, Embase, SCOPUS, Medline, and Cochrane databases. FI and rFI-event reversals needed to alter outco...
Out of 33 studies screened, 19 RCTs comprising 204 outcomes were included, with a median FI of 4 (3 - 5) and FQ of 0.039 (0.029 - 0.070). Twenty-six outcomes achieved statistical significance, with a ...
ADM-related breast reconstruction outcomes are statistically fragile, so reversal of a few outcomes or maintaining follow-up with patients may alter the significance of findings. Future researchers ar...
Chronic kidney disease (CKD) is associated with a substantial risk of progression to end-stage renal disease and vascular events. The nonsteroidal mineralocorticoid receptor antagonist (MRA), finereno...
