Titre : CDPdiacylglycerol-serine O-phosphatidyltransferase

CDPdiacylglycerol-serine O-phosphatidyltransferase : Questions médicales fréquentes

Termes MeSH sélectionnés :

Probability
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"url": "https://questionsmedicales.fr/mesh/D010717?mesh_terms=Probability&page=276#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur CDPdiacylglycerol-serine O-phosphatidyltransferase", "description": "Quels sont les symptômes d'une déficience en cette enzyme ?\nY a-t-il des signes cliniques spécifiques ?\nLes symptômes varient-ils selon l'âge ?\nDes symptômes peuvent-ils être confondus avec d'autres maladies ?\nComment les symptômes évoluent-ils dans le temps ?", "url": "https://questionsmedicales.fr/mesh/D010717?mesh_terms=Probability&page=276#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur CDPdiacylglycerol-serine O-phosphatidyltransferase", "description": "Peut-on prévenir les déficiences enzymatiques ?\nY a-t-il des conseils diététiques pour prévenir des problèmes ?\nLes tests génétiques peuvent-ils aider à la prévention ?\nDes programmes de sensibilisation existent-ils ?\nComment le suivi médical contribue-t-il à la prévention ?", "url": "https://questionsmedicales.fr/mesh/D010717?mesh_terms=Probability&page=276#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur CDPdiacylglycerol-serine O-phosphatidyltransferase", "description": "Quels traitements sont disponibles pour cette déficience ?\nLa thérapie génique est-elle une option ?\nDes médicaments spécifiques existent-ils ?\nComment la nutrition influence-t-elle le traitement ?\nY a-t-il des traitements expérimentaux en cours ?", "url": "https://questionsmedicales.fr/mesh/D010717?mesh_terms=Probability&page=276#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur CDPdiacylglycerol-serine O-phosphatidyltransferase", "description": "Quelles complications peuvent survenir ?\nLes complications sont-elles réversibles ?\nComment les complications affectent-elles la qualité de vie ?\nY a-t-il des risques de maladies associées ?\nComment prévenir les complications ?", "url": "https://questionsmedicales.fr/mesh/D010717?mesh_terms=Probability&page=276#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur CDPdiacylglycerol-serine O-phosphatidyltransferase", "description": "Quels sont les facteurs de risque pour cette déficience ?\nL'environnement joue-t-il un rôle ?\nLes maladies métaboliques augmentent-elles le risque ?\nY a-t-il des groupes à risque particulier ?\nComment le mode de vie influence-t-il le risque ?", "url": "https://questionsmedicales.fr/mesh/D010717?mesh_terms=Probability&page=276#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une déficience en CDPdiacylglycerol-serine O-phosphatidyltransferase ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur des tests enzymatiques et des analyses génétiques." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour évaluer l'activité de l'enzyme ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests biochimiques mesurant l'activité enzymatique dans des échantillons cellulaires." } }, { "@type": "Question", "name": "Y a-t-il des biomarqueurs associés à cette enzyme ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Des biomarqueurs lipidiques peuvent indiquer une dysfonction de l'enzyme." } }, { "@type": "Question", "name": "Quels symptômes peuvent alerter sur un problème enzymatique ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des troubles métaboliques ou des anomalies dans la composition lipidique peuvent survenir." } }, { "@type": "Question", "name": "Peut-on utiliser l'imagerie pour diagnostiquer des anomalies ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'imagerie peut aider à visualiser des complications, mais n'est pas spécifique." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une déficience en cette enzyme ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des troubles neurologiques et des anomalies métaboliques." } }, { "@type": "Question", "name": "Y a-t-il des signes cliniques spécifiques ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Des signes comme des troubles de la croissance ou des problèmes de reproduction peuvent apparaître." } }, { "@type": "Question", "name": "Les symptômes varient-ils selon l'âge ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes peuvent se manifester différemment selon l'âge du patient." } }, { "@type": "Question", "name": "Des symptômes peuvent-ils être confondus avec d'autres maladies ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains symptômes peuvent ressembler à ceux d'autres troubles métaboliques." } }, { "@type": "Question", "name": "Comment les symptômes évoluent-ils dans le temps ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes peuvent s'aggraver avec le temps si non traités." } }, { "@type": "Question", "name": "Peut-on prévenir les déficiences enzymatiques ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est difficile, mais un diagnostic précoce peut aider à gérer la condition." } }, { "@type": "Question", "name": "Y a-t-il des conseils diététiques pour prévenir des problèmes ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée riche en acides gras essentiels peut être bénéfique." } }, { "@type": "Question", "name": "Les tests génétiques peuvent-ils aider à la prévention ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les tests génétiques peuvent identifier les porteurs et aider à la planification familiale." } }, { "@type": "Question", "name": "Des programmes de sensibilisation existent-ils ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Des programmes éducatifs peuvent sensibiliser aux troubles métaboliques héréditaires." } }, { "@type": "Question", "name": "Comment le suivi médical contribue-t-il à la prévention ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi régulier permet de détecter précocement les anomalies et d'ajuster le traitement." } }, { "@type": "Question", "name": "Quels traitements sont disponibles pour cette déficience ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement peut inclure des suppléments lipidiques et une thérapie diététique." } }, { "@type": "Question", "name": "La thérapie génique est-elle une option ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "La thérapie génique est en recherche, mais pas encore largement disponible." } }, { "@type": "Question", "name": "Des médicaments spécifiques existent-ils ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de médicaments spécifiques approuvés pour cette condition." } }, { "@type": "Question", "name": "Comment la nutrition influence-t-elle le traitement ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Une nutrition adéquate peut aider à gérer les symptômes et améliorer la santé globale." } }, { "@type": "Question", "name": "Y a-t-il des traitements expérimentaux en cours ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des études cliniques explorent de nouvelles approches thérapeutiques." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications neurologiques et métaboliques peuvent se développer si non traitées." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être réversibles avec un traitement approprié." } }, { "@type": "Question", "name": "Comment les complications affectent-elles la qualité de vie ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les complications peuvent gravement affecter la qualité de vie et nécessiter un soutien." } }, { "@type": "Question", "name": "Y a-t-il des risques de maladies associées ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des maladies métaboliques ou neurologiques peuvent être associées à cette déficience." } }, { "@type": "Question", "name": "Comment prévenir les complications ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi médical régulier et un traitement précoce peuvent aider à prévenir les complications." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour cette déficience ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les antécédents familiaux et certaines mutations génétiques augmentent le risque." } }, { "@type": "Question", "name": "L'environnement joue-t-il un rôle ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs environnementaux peuvent influencer l'expression des gènes liés à l'enzyme." } }, { "@type": "Question", "name": "Les maladies métaboliques augmentent-elles le risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines maladies métaboliques peuvent prédisposer à des déficiences enzymatiques." } }, { "@type": "Question", "name": "Y a-t-il des groupes à risque particulier ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Les personnes avec des antécédents familiaux de troubles lipidiques sont à risque." } }, { "@type": "Question", "name": "Comment le mode de vie influence-t-il le risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Un mode de vie malsain peut exacerber les symptômes et augmenter le risque de complications." } } ] } ] }

Sources (2756 au total)

Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial.

Switching from intravenous antibiotic therapy to oral antibiotic therapy among neonates is not yet practised in high-income settings due to uncertainties about exposure and safety. We aimed to assess ... In this multicentre, randomised, open-label, non-inferiority trial, patients were recruited at 17 hospitals in the Netherlands. Neonates (postmenstrual age ≥35 weeks, postnatal age 0-28 days, bodyweig... Between Feb 8, 2018 and May 12, 2021, 510 neonates were randomly assigned (n=255 oral amoxicillin-clavulanic group; n=255 intravenous antibiotic group). After excluding those who withdrew consent (n=4... An early intravenous-to-oral antibiotic switch with amoxicillin-clavulanic acid is non-inferior to a full course of intravenous antibiotics in neonates with probable bacterial infection and is not ass... The Netherlands Organization for Health Research and Development, Innovatiefonds Zorgverzekeraars, and the Sophia Foundation for Scientific Research....

'I probably wouldn't want to talk about anything too personal': A qualitative exploration of how issues of privacy, confidentiality and surveillance in the home impact on access and engagement with online services and spaces for care-experienced young people.

This paper draws on a qualitative interview-based study that explored online mental health and wellbeing interventions and services for care-experienced young people. The study involved young people (...

Risk and survival of patients with non-small cell lung cancer and pre-existing autoimmune disorders receiving immune checkpoint blockade therapy: Survival analysis with inverse probability weighting from a nationwide, multi-institutional, retrospective study (NEJ047).

The risk and survival of patients with non-small cell lung cancer (NSCLC) with pre-existing autoimmune disorders (AIDs) receiving immune checkpoint blockade (ICB) therapy have not been clearly establi... This multi-institutional, retrospective cohort study was conducted in collaboration with 20 centers in Japan.... In total, 229 patients with advanced or recurrent NSCLC and pre-existing AID, with or without ICB treatment from January 2010-February 2020, were included and analyzed. Among 69 patients who received ... These findings revealed a novel risk factor for AID flares following ICB treatment, that is the diagnosis of NSCLC within 1 year of AID diagnosis, and showed that ICBs may improve survival in this pop...

Mandibular dose-volume predicts time-to-osteoradionecrosis in an actuarial normal-tissue complication probability (NTCP) model: External validation of right-censored clinico-dosimetric and competing risk application across international multi-institutional observational cohorts and online graphical user interface clinical support tool assessment.

Existing studies on osteoradionecrosis of the jaw (ORNJ) have primarily used cross-sectional data, assessing risk factors at a single time point. Determining the time-to-event profile of ORNJ has impo... Demographic, clinical and dosimetric data were retrospectively obtained for a clinical observational cohort of 1129 patients with HNC treated with radiotherapy (RT) at The University of Texas MD Ander... Our model identified that each unit increase in D25% is significantly associated with a 12% shorter time to ORNJ (Adjusted Time Ratio [ATR] 0·88, p<0·005); pre-RT dental extractions was associated to ... This study is the first to demonstrate a direct relationship between radiation dose and the time to ORNJ onset, providing a novel characterization of the impact of delivered dose not only on the proba... This work was supported by various funding sources including NIH, NIDCR, NCI, NAPT, NASA, BCM, Affirmed Pharma, CRUK, KWF Dutch Cancer Society, NWO ZonMw, and the Apache Corporation....

The World Health Organization Antenatal CorTicosteroids for Improving Outcomes in preterm Newborns (ACTION-III) Trial: study protocol for a multi-country, multi-centre, double-blind, three-arm, placebo-controlled, individually randomized trial of antenatal corticosteroids for women at high probability of late preterm birth in hospitals in low- resource countries.

Preterm birth complications are the leading cause of newborn and under-5 mortality. Over 85% of all preterm births occur in the late preterm period, i.e. between 34 and < 37 weeks of gestation. Antena... WHO ACTION III trial is a parallel-group, three-arm, individually randomized, double-blind, placebo-controlled trial of two ACS regimens: dexamethasone phosphate 4 × 6 mg q12h or betamethasone phospha... This trial will evaluate the benefits and possible harms of ACS when used in women likely to have a late preterm birth. It will also evaluate a lower-dose ACS regimen based on literature from pharmaco... ISRCTN11434567 . Registered on 7 June 2021....