questionsmedicales.fr
Composés chimiques organiques
Composés organiques du phosphore
Organophosphates
Organophosphates : Questions médicales fréquentes
Diagnostic
5
Intoxication
Acétylcholinestérase
Diagnostic
Tests de laboratoire
Cholinestérase
Exposition
Symptômes
Intoxication aiguë
Système nerveux
Évaluation
Symptômes
Acétylcholinestérase
Antécédents médicaux
Pesticides
Exposition
Symptômes
5
Symptômes neurologiques
Convulsions
Tremblements
Symptômes respiratoires
Bronchoconstriction
Toux
Symptômes gastro-intestinaux
Nausées
Vomissements
Signes vitaux
Fréquence cardiaque
Pression artérielle
Symptômes tardifs
Exposition
Intoxication
Prévention
5
Prévention
Équipements de protection
Pesticides
Agriculteurs
Protocoles de sécurité
Produits chimiques
Enfants
Vulnérabilité
Métabolisme
Stockage
Sécurité
Contenants hermétiques
Alternatives
Insecticides biologiques
Lutte intégrée
Traitements
5
Traitement
Atropine
Pralidoxime
Atropine
Récepteurs
Acétylcholine
Pralidoxime
Intoxication sévère
Acétylcholinestérase
Soins de soutien
Oxygénation
Monitoring
Antidotes
Atropine
Pralidoxime
Complications
5
Complications
Troubles neurologiques
Problèmes respiratoires
Séquelles
Intoxication
Neurologiques
Récidive
Exposition
Risques
Surveillance
Examens neurologiques
Tests fonctionnels
Qualité de vie
Complications
Activités quotidiennes
Facteurs de risque
5
Facteurs de risque
Travailleurs agricoles
Zones agricoles
Personnes âgées
Vulnérabilité
Fonction hépatique
Comportements à risque
Consignes de sécurité
Pesticides
Femmes enceintes
Exposition
Développement fœtal
Antécédents médicaux
Maladies respiratoires
Maladies neurologiques
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"name": "Les symptômes peuvent-ils apparaître tardivement ?",
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"name": "Comment prévenir l'exposition aux organophosphates ?",
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"text": "Utiliser des équipements de protection individuelle lors de l'application de pesticides."
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"name": "Quelles sont les recommandations pour les agriculteurs ?",
"position": 12,
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"text": "Les agriculteurs doivent suivre les protocoles de sécurité et les instructions d'utilisation des produits."
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"name": "Quelles sont les alternatives aux organophosphates ?",
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"position": 18,
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{
"@type": "Question",
"name": "Comment les complications sont-elles surveillées ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications sont surveillées par des examens neurologiques réguliers et des tests fonctionnels."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles affecter la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent significativement affecter la qualité de vie et les activités quotidiennes."
}
},
{
"@type": "Question",
"name": "Qui est le plus à risque d'intoxication ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les travailleurs agricoles et les personnes vivant près des zones agricoles sont les plus à risque."
}
},
{
"@type": "Question",
"name": "Les personnes âgées sont-elles plus vulnérables ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées peuvent être plus vulnérables en raison de la diminution de la fonction hépatique."
}
},
{
"@type": "Question",
"name": "Quels comportements augmentent le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le non-respect des consignes de sécurité lors de l'utilisation de pesticides augmente le risque."
}
},
{
"@type": "Question",
"name": "Les femmes enceintes sont-elles à risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition pendant la grossesse peut affecter le développement du fœtus."
}
},
{
"@type": "Question",
"name": "Les personnes avec des antécédents médicaux sont-elles plus à risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes ayant des antécédents de maladies respiratoires ou neurologiques sont plus à risque."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 26/07/2026
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Protection and Resources Utilization, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Institute of Quality Standard and Testing Technology for Agro-Products, The Chinese Academy of Agricultural Sciences (CAAS), Beijing 100081, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Institute of Quality Standard and Testing Technology for Agro-Products, The Chinese Academy of Agricultural Sciences (CAAS), Beijing 100081, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Institute of Quality Standard and Testing Technology for Agro-Products, The Chinese Academy of Agricultural Sciences (CAAS), Beijing 100081, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Institute of Quality Standard and Testing Technology for Agro-Products, The Chinese Academy of Agricultural Sciences (CAAS), Beijing 100081, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Institute of Quality Standard and Testing Technology for Agro-Products, The Chinese Academy of Agricultural Sciences (CAAS), Beijing 100081, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), School of Environmental Science and Technology, Dalian University of Technology, Dalian 116024, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Department of Environmental Chemistry, Jordi Girona, 18, 08034 Barcelona, Catalonia, Spain.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Department of Environmental Chemistry, Jordi Girona, 18, 08034 Barcelona, Catalonia, Spain. Electronic address: joan.grimalt@idaea.csic.es.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Department of Earth Sciences, University of Toronto, 22 Ursula Franklin Street, Toronto, Ontario M5S 3B1, Canada.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology, Dalian 116024, China. Electronic address: wangyandut@dlut.edu.cn.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology, Dalian 116024, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
School of Environment, Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety & MOE Key Laboratory of Theoretical Chemistry of Environment, South China Normal University, Guangzhou, 510006, China.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
School of Environment, Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety & MOE Key Laboratory of Theoretical Chemistry of Environment, South China Normal University, Guangzhou, 510006, China. Electronic address: shejun.chen@m.scnu.edu.cn.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Fish Ecophysiology, Department of Fisheries Management, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Fish Ecophysiology, Department of Fisheries Management, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Academic Department of Chemistry and Biology, Universidade Tecnológica Federal do Paraná, 81280-340, Curitiba-PR, Brazil.
Department of Chemistry, Universidade Federal do Paraná, CP 19081, CEP 81531-990, Curitiba-PR, Brazil.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Universidade Federal do Paraná, CP 19081, CEP 81531-990, Curitiba-PR, Brazil.
Publications dans "Organophosphates" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Universidade Federal do Paraná, CP 19081, CEP 81531-990, Curitiba-PR, Brazil.
Publications dans "Organophosphates" :
Organophosphate flame retardants (OPFRs) are an important group of pollutants associated with endocrine disorders, cancer, and nephrotoxicity. However, temporal trends in OPFR metabolite concentration...
To examine changes in urinary concentrations of OPFR metabolites among US children, youths, and adults from 2011 to 2020, and to evaluate whether sociodemographic factors were associated with variatio...
This population-based cross-sectional study used data from 4 US National Health and Nutrition Examination Survey (NHANES) cycles (2011-2012, 2013-2014, 2015-2016, and 2017-2020 [to March 2020 before t...
Calendar year and key sociodemographic subgroups (age, race and ethnicity, sex, educational attainment, and poverty-to-income ratio)....
The main outcome was urinary concentrations of OPFR metabolites among children, youths, and adults. Survey-weighted linear regression models were applied to estimate trends....
The study population of 10 549 NHANES participants included 3154 children and youths (mean [SE] age, 12.5 [0.1] years; 51.2% were male) and 7395 adults (mean [SE] age, 47.8 [0.4] years; 52.0% were wom...
This study identified variations in temporal trends in urinary concentrations of OPFR metabolites among the US population from 2011 to 2020. In addition, substantial disparities in exposure levels per...
Owing to their potential to cause serious adverse health effects, significant efforts have been made to develop antidotes for organophosphate (OP) anticholinesterases, such as nerve agents. To be opti...
Organophosphate esters (OPEs) have been broadly used in various industrial and consumer products, resulting in global distribution and human exposure. Gestational exposure to OPEs may adversely affect...
Controversy exists with regard to risk of secondary exposure of health care workers caring for patients who have ingested an organophosphate insecticide. We aim to report clinical effects of staff mem...
A 76-year-old male presented to the Emergency Department exhibiting a cholinergic toxidrome requiring atropine, intubation and mechanical ventilation....
We undertook a retrospective chart review of any Emergency Department presentations for medical assessment in relation to the incident and conducted telephone interviews of any healthcare workers who ...
We collected data from 13 individuals, of whom nine presented for medical assessment, including the patient's spouse. Five additional staff members were interviewed, having been identified via Emergen...
We found no clinical nor biochemical evidence of toxicity in healthcare workers caring for a critically ill patient with organophosphate ingestion. These findings are consistent with previously publis...
This review examines recent advancements in electrochemical immunosensors for the detection of organophosphate pesticides, focusing on strategies to enhance sensitivity and selectivity. The widespread...
The general population and workers are exposed to organophosphate insecticides, one of the leading chemical classes of pesticides used in rural and urban areas, in the control of arboviruses and agric...
Organophosphate esters (OPEs) are flame retardants and plasticizers used in consumer products. OPEs are found ubiquitously throughout the environment with high concentrations in indoor house dust. Exp...
The objectives of this study were to evaluate the toxicity of an environmentally relevant mixture of OPEs that models Canadian house dust on macrophages using phenotypic and functional assessments...
High-content live-cell fluorescent imaging for phenotypic biomarkers of toxicity in THP-1 macrophages treated with the OPE mixture was undertaken. We used confocal microscopy and cholesterol analysis ...
Exposure to non-cytotoxic dilutions of the OPE mixture resulted in higher oxidative stress and disrupted lysosome and lipid homeostasis in THP-1 and primary macrophages. We further observed that phago...
The results of this...
Organophosphite antioxidants (OPAs) have been seriously neglected as potential sources of organophosphate esters (OPEs) in environments. This study utilizes a modeling approach to quantify for the fir...
Evidence regarding the relationships between organophosphate flame retardants (OPFRs) and hyperuricemia and gout as well as the underlying mechanisms remains scarce, but some evidence indicates that i...
Using an integrated approach, we aim to elucidate the associations of urinary metabolite OPFRs (m-OPFRs) with hyperuricemia and gout....
Cross-sectional analyses using data from the National Health and Nutrition Examination Survey were performed to reveal the associations. Adults with complete data on five m-OPFRs with high detection f...
Multivariate logistic models revealed that bis(2-chloroethyl) phosphate (BCEP) significantly increased risk of hyperuricemia (OR [95 % CI]: 1.165 [1.047, 1.296]) in the fully adjusted model. Elevated ...
Our results first revealed that individual and mixed OPFRs were associated with hyperuricemia, in which the inflammatory response plays an important role. Further longitudinal studies are warranted to...
The association of prenatal exposure to organophosphate esters (OPEs) and replacement brominated flame retardants (RBFRs) with respiratory outcomes has not been previously investigated in humans, desp...
In a cohort of 342 pregnant women recruited between 2003 and 2006 in the greater Cincinnati, Ohio Metropolitan area, we measured indoor dust OPEs and RBFRs at 20 weeks of gestation and urinary OPEs at...
Dust concentrations of triphenyl phosphate (TPHP) (RR: 1.40, 95% CI: 1.18-1.66), 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (RR: 1.51, 95% CI: 1.23-1.85), and bis(2-ethylhexyl) tetrabromophthalate (RR: 1...
In-utero exposure to OPEs and RBFRs may be a risk factor for adverse respiratory outcomes in childhood, depending on the timing of exposure....