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"description": "Comment déterminer la phylogénie d'une espèce ?\nQuels outils sont utilisés en phylogénie ?\nQu'est-ce qu'un arbre phylogénétique ?\nQuelle est l'importance de la phylogénie ?\nComment la phylogénie aide-t-elle en médecine ?",
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"@type": "Question",
"name": "Comment déterminer la phylogénie d'une espèce ?",
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"text": "On utilise des analyses génétiques et morphologiques pour établir des relations évolutives."
}
},
{
"@type": "Question",
"name": "Quels outils sont utilisés en phylogénie ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les outils incluent les arbres phylogénétiques et les logiciels de bioinformatique."
}
},
{
"@type": "Question",
"name": "Qu'est-ce qu'un arbre phylogénétique ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "C'est une représentation graphique des relations évolutives entre différentes espèces."
}
},
{
"@type": "Question",
"name": "Quelle est l'importance de la phylogénie ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle aide à comprendre l'évolution des espèces et leur adaptation à l'environnement."
}
},
{
"@type": "Question",
"name": "Comment la phylogénie aide-t-elle en médecine ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet de tracer l'origine des pathogènes et d'identifier des cibles thérapeutiques."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer une évolution rapide ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des changements rapides dans les traits d'une population peuvent signaler une évolution."
}
},
{
"@type": "Question",
"name": "Comment les symptômes évolutifs se manifestent-ils ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent se manifester par des variations morphologiques ou comportementales."
}
},
{
"@type": "Question",
"name": "Les symptômes peuvent-ils être liés à la phylogénie ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains symptômes peuvent être hérités et refléter des relations évolutives."
}
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{
"@type": "Question",
"name": "Quels symptômes sont observés chez les espèces en danger ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes de stress, de déclin de la reproduction et de perte de diversité peuvent apparaître."
}
},
{
"@type": "Question",
"name": "Comment les symptômes évolutifs influencent-ils la survie ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent affecter l'adaptation et la capacité de survie dans un environnement changeant."
}
},
{
"@type": "Question",
"name": "Comment la phylogénie contribue-t-elle à la prévention des maladies ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle aide à identifier les souches pathogènes et à développer des stratégies de vaccination."
}
},
{
"@type": "Question",
"name": "Quels rôles jouent les études phylogénétiques en santé publique ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles permettent de surveiller les épidémies et de comprendre la transmission des maladies."
}
},
{
"@type": "Question",
"name": "Comment prévenir la propagation des pathogènes ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "En utilisant des données phylogénétiques pour cibler les interventions de santé publique."
}
},
{
"@type": "Question",
"name": "La phylogénie peut-elle aider à prévenir les zoonoses ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet d'identifier les espèces réservoirs et de réduire les risques de transmission."
}
},
{
"@type": "Question",
"name": "Quels sont les défis de la prévention basée sur la phylogénie ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les changements rapides des pathogènes peuvent compliquer les efforts de prévention."
}
},
{
"@type": "Question",
"name": "Comment la phylogénie influence-t-elle les traitements médicaux ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet de développer des traitements ciblés basés sur les relations évolutives des pathogènes."
}
},
{
"@type": "Question",
"name": "Quels traitements sont basés sur la phylogénie ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les vaccins et les thérapies géniques peuvent être développés en tenant compte de la phylogénie."
}
},
{
"@type": "Question",
"name": "La phylogénie aide-t-elle à la découverte de médicaments ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle guide la recherche de nouvelles molécules en identifiant des cibles évolutives."
}
},
{
"@type": "Question",
"name": "Quels sont les défis des traitements basés sur la phylogénie ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les variations génétiques rapides des pathogènes peuvent rendre les traitements moins efficaces."
}
},
{
"@type": "Question",
"name": "Comment la phylogénie aide-t-elle à prévenir les résistances ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet d'anticiper les mutations et d'adapter les traitements pour éviter les résistances."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir en cas d'évolution rapide ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des résistances aux traitements et des épidémies peuvent survenir en raison d'évolutions rapides."
}
},
{
"@type": "Question",
"name": "Comment la phylogénie aide-t-elle à comprendre les complications ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet d'analyser les relations entre les souches et les complications associées."
}
},
{
"@type": "Question",
"name": "Quelles complications sont liées aux infections virales ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections virales peuvent entraîner des complications respiratoires et neurologiques."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être prédites par la phylogénie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, en étudiant les relations évolutives, on peut prédire certaines complications potentielles."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications liées à la phylogénie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une surveillance continue et des ajustements de traitement sont essentiels pour gérer les complications."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque influencent l'évolution des pathogènes ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les mutations génétiques, l'environnement et les interactions hôtes-pathogènes sont cruciaux."
}
},
{
"@type": "Question",
"name": "Comment l'environnement affecte-t-il la phylogénie ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les changements environnementaux peuvent favoriser certaines adaptations et influencer l'évolution."
}
},
{
"@type": "Question",
"name": "Quels comportements augmentent les risques d'infection ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des comportements comme le non-respect des mesures d'hygiène et la surpopulation augmentent les risques."
}
},
{
"@type": "Question",
"name": "Les voyages influencent-ils la phylogénie des maladies ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les voyages facilitent la propagation des souches et augmentent le risque d'épidémies."
}
},
{
"@type": "Question",
"name": "Comment la biodiversité affecte-t-elle les risques de maladies ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une biodiversité élevée peut réduire les risques de maladies en limitant la transmission entre espèces."
}
}
]
}
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To ensure satisfactory clinical outcomes, surgical skill assessment must be objective, time-efficient, and preferentially automated-none of which is currently achievable. Video-based assessment (VBA) ...
Suicidal ideation is a serious symptom of major depressive disorder (MDD). Intermittent theta burst stimulation (iTBS) is a safe, effective brain stimulation treatment for alleviating suicidal ideatio...
In a randomized, sham-controlled protocol, a total of 10 sessions of iTBS was administrated to the left dorsolateral prefrontal cortex (DLPFC) in patients once a day for two weeks. The suicidal ideati...
Forty-five patients were randomized assigned to either active iTBS (n = 23) or sham group (n = 22). The suicidal ideation and depressive symptoms of the active iTBS group were significantly ameliorate...
A larger sample size and double-blinded clinical trial should be conducted to verify the reliability and reproducibility....
The current study suggested that daily iTBS of the left DLPFC for 2 weeks could effectively and safely alleviate suicidal ideation and mitigate depression in adolescent MDD, especially for individuals...
The International Index of Erectile Function (IIEF) is a widely employed questionnaire in urology to assess erectile dysfunction (ED) in both clinical research and practice....
To translate and culturally adapt the Spanish version of the International Index of Erectile Function (IIEF) and to analyze its psychometric properties in Spanish men with erectile dysfunction (ED)....
Firstly, direct and reverse translations were performed. Secondly, a pilot study was carried out on 23 patients with the lowest possible education level without being illiterate. Finally, 170 particip...
High internal consistency (Cronbach's alpha = 0.968, total score) and moderate-to-excellent test-retest reliability were found. The factor analysis showed a two-factor structure (explained variance of...
The psychometric properties of the IIEF have not been analyzed in Spanish people to date. Strengths and Limitations: The Spanish version of the IIEF was shown to be capable of discriminating between m...
The Spanish IIEF is a valid and reliable instrument for assessing erectile function among Spanish men with ED....
Building experience in midwife-led care at freestanding midwifery units is needed to enhance assessment, technical, and care competencies specific to midwives. This study aimed to develop a self-asses...
The purpose of this study was to translate and cross-culturally adapt the Achilles Tendon Total Rupture Score (ATRS), a patient-reported outcome measurement (PROM) designed specifically to assess outc...
The ATRS was translated into the Thai version (Thai-ATRS) according to internationally recognized guidelines. The study included 50 patients with Achilles tendon rupture from 2003 to 2017. The web-bas...
The validity test displayed a strong correlation between the Thai-ATRS and the Thai-FAOS (r = 0.87). The reliability test showed good internal consistency with a Cronbach's alpha of 0.95 and excellent...
The Thai-ATRS was demonstrated to be valid and reliable for assessing functional outcomes in Thai patients with Achilles tendon rupture....
II....
To investigate interstitial muscle fibrosis via T1 mapping indices and its relationships with muscle function and conservative treatment outcomes....
A total of 49 DM patients with PAD were prospectively recruited from 2016 to 2017. All PAD patients underwent pre-treatment MRI with conservative treatment via a rehabilitation program and antiplatele...
Among the T1 mapping indices in the posterior compartment of the calf in PAD patients, the native T1 value was significantly correlated with 6MWT (r = -0.422, p = 0.010) and 3MST (r = -0.427, p = 0.00...
T1 mapping measurements are reproducible with excellent intra-observer and inter-observer correlations. T1 mapping indices may be predictive of treatment and functional outcomes and carry promise in p...
Clinical Trials Identifier: NCT02850432 ....
• T1 mapping measurements of the calf muscles are reproducible with excellent intra-observer and inter-observer correlations (0.98 and 0.95 for anterior and posterior compartment muscle extracellular ...
The burden of COVID-19 on healthcare workers (HCWs) is reported to be increasing, yet the psychometric scales now in use evaluate only single aspects; few measure the pandemic-specific burden on HCWs ...
To develop a scale to quantify the physical, mental, and socioeconomic burden of the COVID-19 pandemic on HCWs....
Scale development and cross-sectional survey....
Consenting HCWs aged ≥20....
Development of an item-list based on literature reviews and HCW panel input, evaluation of content validity and item selection using the Delphi method, psychometric testing conducted on HCWs, validity...
Through the Delphi process, a 29-item pilot scale was generated. In psychometric testing, data from 863 HCWs contributed to the development of the final version of this scale, called Pandemic Burden I...
The psychometrically sound questionnaire we developed to measure pandemic-specific burdens for HCWs provides an understanding of comprehensive burdens on HCWs and may serve to evaluate interventions t...
Biosurfactants produced by Bacillus species are an emerging group of surface-active molecules. They have excellent surface tension reducer and high emulsifier properties. Generally, the biosurfactant ...
The purpose of the present study is to build a model combining some variables that have been previously studied separately to improve our understanding on how they relate in parents of children with c...
The identification of drugs or biomolecules for public health monitoring requires facile analytical technologies with excellent sensitivity, portability and reliability. In the past decades, different...