Titre : Protein-arginine N-methyltransferases

Protein-arginine N-methyltransferases : Questions médicales fréquentes

Termes MeSH sélectionnés :

Sensitivity and Specificity
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liés à ces enzymes ?\nPeut-on observer des symptômes neurologiques ?\nY a-t-il des symptômes spécifiques chez les enfants ?\nComment les symptômes varient-ils selon l'âge ?", "url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Sensitivity+and+Specificity&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Protein-arginine N-methyltransferases", "description": "Comment prévenir les troubles liés aux N-méthyltransférases ?\nY a-t-il des mesures préventives spécifiques ?\nL'éducation sur la santé est-elle importante ?\nLes vaccinations jouent-elles un rôle préventif ?\nComment le suivi médical aide-t-il à la prévention ?", "url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Sensitivity+and+Specificity&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Protein-arginine N-methyltransferases", "description": "Quels traitements existent pour les dysfonctionnements enzymatiques ?\nLes médicaments peuvent-ils aider à réguler ces enzymes ?\nY a-t-il des thérapies géniques disponibles ?\nComment la nutrition influence-t-elle le traitement ?\nLes traitements sont-ils personnalisés ?", "url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Sensitivity+and+Specificity&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Protein-arginine N-methyltransferases", "description": "Quelles complications peuvent survenir avec ces troubles ?\nLes troubles cardiovasculaires sont-ils possibles ?\nComment les complications affectent-elles la qualité de vie ?\nY a-t-il des complications à long terme ?\nLes complications peuvent-elles être évitées ?", "url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Sensitivity+and+Specificity&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Protein-arginine N-methyltransferases", "description": "Quels sont les facteurs de risque associés ?\nL'environnement joue-t-il un rôle ?\nLe mode de vie affecte-t-il le risque ?\nLes infections peuvent-elles être un facteur de risque ?\nY a-t-il des groupes à risque spécifiques ?", "url": "https://questionsmedicales.fr/mesh/D011484?mesh_terms=Sensitivity+and+Specificity&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dysfonction des N-méthyltransférases ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques et des analyses biochimiques peuvent être utilisés pour diagnostiquer." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour évaluer l'activité enzymatique ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests enzymatiques spécifiques mesurent l'activité des N-méthyltransférases dans les échantillons." } }, { "@type": "Question", "name": "Y a-t-il des biomarqueurs associés à ces enzymes ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Des biomarqueurs comme la méthylation de l'arginine peuvent indiquer une activité enzymatique." } }, { "@type": "Question", "name": "Quels symptômes peuvent indiquer un problème enzymatique ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes variés comme des troubles neurologiques ou immunitaires peuvent survenir." } }, { "@type": "Question", "name": "Comment les tests génétiques aident-ils au diagnostic ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Ils identifient des mutations spécifiques dans les gènes codant pour ces enzymes." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une carence en N-méthyltransférases ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent fatigue, troubles cognitifs et anomalies immunitaires." } }, { "@type": "Question", "name": "Les troubles de l'humeur sont-ils liés à ces enzymes ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des déséquilibres peuvent affecter l'humeur et contribuer à des troubles psychiatriques." } }, { "@type": "Question", "name": "Peut-on observer des symptômes neurologiques ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles neurologiques comme des convulsions peuvent être présents." } }, { "@type": "Question", "name": "Y a-t-il des symptômes spécifiques chez les enfants ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Les enfants peuvent présenter des retards de développement et des troubles d'apprentissage." } }, { "@type": "Question", "name": "Comment les symptômes varient-ils selon l'âge ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes peuvent être plus prononcés chez les jeunes enfants et les personnes âgées." } }, { "@type": "Question", "name": "Comment prévenir les troubles liés aux N-méthyltransférases ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir ces troubles." } }, { "@type": "Question", "name": "Y a-t-il des mesures préventives spécifiques ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Des dépistages précoces et des conseils génétiques peuvent être bénéfiques." } }, { "@type": "Question", "name": "L'éducation sur la santé est-elle importante ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, sensibiliser les patients et les familles peut aider à identifier les symptômes tôt." } }, { "@type": "Question", "name": "Les vaccinations jouent-elles un rôle préventif ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Certaines vaccinations peuvent prévenir des infections qui aggravent les symptômes." } }, { "@type": "Question", "name": "Comment le suivi médical aide-t-il à la prévention ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi régulier permet de surveiller l'état de santé et d'ajuster les traitements." } }, { "@type": "Question", "name": "Quels traitements existent pour les dysfonctionnements enzymatiques ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements peuvent inclure des suppléments nutritionnels et des thérapies ciblées." } }, { "@type": "Question", "name": "Les médicaments peuvent-ils aider à réguler ces enzymes ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains médicaments peuvent moduler l'activité des N-méthyltransférases." } }, { "@type": "Question", "name": "Y a-t-il des thérapies géniques disponibles ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des recherches sont en cours sur les thérapies géniques pour corriger les mutations." } }, { "@type": "Question", "name": "Comment la nutrition influence-t-elle le traitement ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation riche en nutriments peut soutenir la fonction enzymatique." } }, { "@type": "Question", "name": "Les traitements sont-ils personnalisés ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les traitements peuvent être adaptés en fonction des besoins individuels du patient." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec ces troubles ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications neurologiques, immunitaires et métaboliques peuvent se développer." } }, { "@type": "Question", "name": "Les troubles cardiovasculaires sont-ils possibles ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des déséquilibres peuvent augmenter le risque de maladies cardiovasculaires." } }, { "@type": "Question", "name": "Comment les complications affectent-elles la qualité de vie ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent entraîner des limitations fonctionnelles et des besoins de soins accrus." } }, { "@type": "Question", "name": "Y a-t-il des complications à long terme ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des complications chroniques peuvent affecter la santé globale et le bien-être." } }, { "@type": "Question", "name": "Les complications peuvent-elles être évitées ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être évitées par un traitement précoce et approprié." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque associés ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, des mutations génétiques et des carences nutritionnelles." } }, { "@type": "Question", "name": "L'environnement joue-t-il un rôle ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs environnementaux comme la pollution peuvent influencer la fonction enzymatique." } }, { "@type": "Question", "name": "Le mode de vie affecte-t-il le risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Un mode de vie sédentaire et une mauvaise alimentation augmentent le risque de troubles." } }, { "@type": "Question", "name": "Les infections peuvent-elles être un facteur de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections peuvent exacerber les symptômes et augmenter le risque de complications." } }, { "@type": "Question", "name": "Y a-t-il des groupes à risque spécifiques ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Les personnes avec des antécédents familiaux ou des troubles métaboliques sont plus à risque." } } ] } ] }

Sources (10000 au total)

Sensitivity and Specificity of US and CT as Diagnostic Tools for Pediatric Lateral Neck Abscesses.

Ultrasound (US) and computed tomography (CT) are commonly used in the diagnosis of pediatric neck abscesses. The objective of this study is to determine the sensitivity and specificity of US and CT in... Retrospective review of pediatric patients admitted to a tertiary care center from January 1, 2011, to December 31, 2020, with neck abscesses.... Tertiary care center.... The sensitivity and specificity of US and CT were calculated by comparing imaging performed within 24 h of incision and drainage (I&D). Multiple regression was used to evaluate the association of clin... There were 171 patients included in this study, with a median age of 1.5 years (interquartile range [IQR]: 1-5 years). I&D was done in 156 patients (91.2%), while 15 (8.8%) were treated with antibioti... Neck US has a low sensitivity for diagnosing pediatric neck abscesses, when compared to CT, but remains a useful initial investigation given its high PPV. Clinicians should have a low threshold for pu... Level 4....

Sensitivity and specificity of microRNA-204, CA125, and CA19.9 as biomarkers for diagnosis of ovarian cancer.

Ovarian cancer is usually detected at later stages and no effective screening approach, has been identified. Therefore, sensitive and specific biomarkers for detecting ovarian cancer are urgently need... This study aimed to investigate the efficacy of six biomarkers for the early clinical diagnosis of ovarian cancer.... The study included 120 patients (benign ovarian tumors and early and late ovarian carcinoma) and 30 control healthy volunteers. MiRNA-204, CA125, CA19.9, hepcidin, microfibril-associated glycoprotein ... The combined area under the receiver operating characteristic curves for miRNA-204, CA125, and CA19.9 were 0.938, 1.000, and 0.998 for benign tumors and early and late ovarian carcinomas, respectively... The positive predictivity of miRNA-204, CA125, and CA19.9 for ovarian cancer is high (59.57%, 58.24%, and 61.67%, respectively). Thus, the combination of these three biomarkers is a good diagnostic to...

Parental sensitivity and specificity to recognize shunt malfunction in their child: a single-center prospective study.

The objective of this study was to estimate the diagnostic performance (sensitivity, specificity, positive predictive value, and negative predictive value) for recognizing ventriculoperitoneal shunt (... A prospective cohort study was conducted between 2021 and 2022 including all patients 0-18 years of age who had a VPS and attended the hospital's ER with symptoms that could correspond to VPS blockage... Ninety-one patients were surveyed, and 59.3% showed evidence of a confirmed VPS blockage. Parental sensitivity was 66.7%, with a specificity of 21.6%. An association was found between parents who coul... Parents who are more knowledgeable of their child's disease, as well as parents who have good communication with their neurosurgeon, were found to have better diagnostic sensitivity....

Comparison of different plaque indices with regard to sensitivity and specificity for the quantification of plaque during orthodontic therapy.

To compare four plaque indices used in orthodontics. An objective, quantitative plaque index and three subjective conventional plaque indices were analyzed. The study included n = 50 photographs of n ...

Sensitivity and specificity of nuclear medicines (DTPA and DMSA) with magnetic resonance imaging in diagnosing bone metastasis.

The frequency of bone metastases in individuals increases at advanced stages of cancer, mostly in patients suffering from lung, breast, or prostate cancer. The study aims to evaluate the effectiveness... Retrospective study design was adopted for the analysis of 120 recruited patients (with the presence of bone metastasis) following a series of examinations and tests.... Better sensitivity (73.33%) and specificity (94.66%) for MRI as compared to SPECT. MRI also proved to be more sensitive (68%) and specific (95.74%), as compared to the findings of the CT scan.... The results conclude that MRI provided favorable diagnostic performance for bone metastasis. It emphasizes that diagnosis using MRI may enable practitioners to devise optimal carcinoma treatment strat...

Sensitivity and specificity of using exercise heart rate in a thermoneutral environment to predict heat tolerance status.

Following heat illness, a return to activity may require passing a heat tolerance test (HTT). However, there are several logistical limitations to the widespread use of the HTT. Thus, it would be adva... Sixty-five subjects visited the lab on 3 separate days. The first visit consisted of completing a maximal oxygen uptake (VO2 max) test to assess cardiovascular fitness. For lab visits 2 and 3, subject... Forty-eight subjects were classified as heat-intolerant and 17 subjects as heat-tolerant. Using the criterion of a HR ≥130 bpm at 30 min of exercise in the thermoneutral environment, specificity (54%)... Exercise in a thermoneutral environment had a positive predictive value of 100%, thus, if a subject has a HR ≥130 bpm at 30 min of exercise in a thermoneutral environment, they are very likely to fail...