Titre : Séquences d'acides nucléiques régulatrices

Séquences d'acides nucléiques régulatrices : Questions médicales fréquentes

Termes MeSH sélectionnés :

Cataract Extraction
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sensibilisation ?", "url": "https://questionsmedicales.fr/mesh/D012045?mesh_terms=Cataract+Extraction&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Séquences d'acides nucléiques régulatrices", "description": "Quels traitements ciblent les séquences régulatrices ?\nPeut-on corriger des mutations régulatrices ?\nLes traitements sont-ils personnalisés ?\nQuels sont les défis des traitements ?\nY a-t-il des essais cliniques en cours ?", "url": "https://questionsmedicales.fr/mesh/D012045?mesh_terms=Cataract+Extraction&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Séquences d'acides nucléiques régulatrices", "description": "Quelles complications peuvent survenir ?\nLes complications sont-elles héréditaires ?\nComment les complications sont-elles gérées ?\nY a-t-il des risques de récidive ?\nLes complications affectent-elles la qualité de vie ?", "url": "https://questionsmedicales.fr/mesh/D012045?mesh_terms=Cataract+Extraction&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Séquences d'acides nucléiques régulatrices", "description": "Quels sont les facteurs de risque génétiques ?\nL'environnement influence-t-il ces séquences ?\nLe mode de vie joue-t-il un rôle ?\nLes infections sont-elles un facteur de risque ?\nY a-t-il des facteurs de risque liés à l'âge ?", "url": "https://questionsmedicales.fr/mesh/D012045?mesh_terms=Cataract+Extraction&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment identifier une séquence régulatrice ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "L'identification se fait par des techniques comme la PCR et le séquençage." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour analyser les séquences régulatrices ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests comme l'empreinte génétique et l'analyse de l'expression génique sont utilisés." } }, { "@type": "Question", "name": "Peut-on détecter des mutations dans ces séquences ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des mutations peuvent être détectées par séquençage ciblé ou NGS." } }, { "@type": "Question", "name": "Quels marqueurs sont associés aux séquences régulatrices ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les marqueurs épigénétiques comme la méthylation de l'ADN sont souvent associés." } }, { "@type": "Question", "name": "Comment évaluer l'activité d'une séquence régulatrice ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'activité peut être évaluée par des essais de reporter génique." } }, { "@type": "Question", "name": "Quels symptômes sont liés à des anomalies régulatrices ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des anomalies peuvent entraîner des maladies génétiques, des cancers ou des troubles métaboliques." } }, { "@type": "Question", "name": "Les séquences régulatrices affectent-elles le développement ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles jouent un rôle crucial dans le développement embryonnaire et cellulaire." } }, { "@type": "Question", "name": "Peut-on observer des symptômes neurologiques ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Certaines mutations régulatrices peuvent être liées à des troubles neurologiques." } }, { "@type": "Question", "name": "Les troubles hormonaux sont-ils liés à ces séquences ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des séquences régulatrices peuvent influencer la régulation hormonale." } }, { "@type": "Question", "name": "Y a-t-il des symptômes immunologiques associés ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des anomalies peuvent entraîner des dysfonctionnements du système immunitaire." } }, { "@type": "Question", "name": "Comment prévenir les maladies liées aux séquences régulatrices ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention passe par le dépistage génétique et la sensibilisation aux facteurs de risque." } }, { "@type": "Question", "name": "Les conseils génétiques sont-ils utiles ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils aident à évaluer le risque et à prendre des décisions éclairées." } }, { "@type": "Question", "name": "Peut-on éviter les mutations par des choix de vie ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Certains choix de vie, comme l'alimentation et l'exercice, peuvent réduire les risques." } }, { "@type": "Question", "name": "Les vaccinations jouent-elles un rôle ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Certaines vaccinations peuvent prévenir des infections qui influencent l'expression génique." } }, { "@type": "Question", "name": "Y a-t-il des programmes de sensibilisation ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des programmes éducatifs sensibilisent aux maladies génétiques et à leur prévention." } }, { "@type": "Question", "name": "Quels traitements ciblent les séquences régulatrices ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Des thérapies géniques et des médicaments ciblant des voies spécifiques sont en développement." } }, { "@type": "Question", "name": "Peut-on corriger des mutations régulatrices ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Des techniques comme CRISPR permettent de corriger certaines mutations." } }, { "@type": "Question", "name": "Les traitements sont-ils personnalisés ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la médecine personnalisée adapte les traitements selon le profil génétique." } }, { "@type": "Question", "name": "Quels sont les défis des traitements ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Les défis incluent la spécificité, l'efficacité et les effets secondaires potentiels." } }, { "@type": "Question", "name": "Y a-t-il des essais cliniques en cours ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, de nombreux essais cliniques explorent des thérapies ciblant ces séquences." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent des cancers, des troubles métaboliques et des maladies auto-immunes." } }, { "@type": "Question", "name": "Les complications sont-elles héréditaires ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être héréditaires, liées à des mutations dans les séquences régulatrices." } }, { "@type": "Question", "name": "Comment les complications sont-elles gérées ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "La gestion implique un suivi médical régulier et des traitements adaptés." } }, { "@type": "Question", "name": "Y a-t-il des risques de récidive ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains troubles peuvent avoir un risque de récidive, nécessitant une surveillance." } }, { "@type": "Question", "name": "Les complications affectent-elles la qualité de vie ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles peuvent significativement impacter la qualité de vie des patients." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque génétiques ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Des antécédents familiaux de maladies génétiques augmentent le risque." } }, { "@type": "Question", "name": "L'environnement influence-t-il ces séquences ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs environnementaux comme les toxines peuvent affecter l'expression génique." } }, { "@type": "Question", "name": "Le mode de vie joue-t-il un rôle ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes comme le tabagisme et l'alimentation peuvent influencer le risque." } }, { "@type": "Question", "name": "Les infections sont-elles un facteur de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections peuvent déclencher des modifications dans les séquences régulatrices." } }, { "@type": "Question", "name": "Y a-t-il des facteurs de risque liés à l'âge ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le risque de maladies génétiques augmente avec l'âge." } } ] } ] }

Sources (10000 au total)

Femtosecond laser assisted cataract surgery in a cataract patient with low vaulted ICL following LASIK: a case report.

Apart from the conventional utilization of ICL implantation for the correction of refractive errors, its recent applications extend to correcting refractive errors post laser refractive surgery. Notab... A 46-year-old male presented with vision loss in the right eye for 9 months, and he had undergone LASIK 22 years prior and had ICL implantation in both eyes 2 years ago to correct refractive error. On... Our report confirms the feasibility of FLACS in managing cataracts in patients with low vault ICL following LASIK. This procedure does not pose significantly greater challenges than in typical catarac...

Immediate sequential bilateral cataract surgery: a 13-year real-life report of 56 700 cataract operations.

To assess the frequency of immediate sequential bilateral cataract surgery (ISBCS) and endophthalmitis during 13-year period in Tays Eye Centre, Tampere University Hospital, Tampere, Finland.... All cataract surgeries performed between 1 January 2008 and 31 December 2020, and all endophthalmitis cases during the same period were searched from electronic patient records. Numbers and frequencie... The study included 56 700 cataract surgeries in 34 797 patients of whom 39% (n=13 445) had ISBCS. The median age of the patients was 75 (IQR 68-80, range 0.08-99) years at the time of surgery. The pro... The proportion of patients undergoing ISBCS increased from 4.2% in 2008 to 46% in 2020. No endophthalmitis were found to be associated with ISBCS....

23G Minimally Invasive Vitrectomy Combined with Glaucoma Drainage Valve Implantation and Phacoemulsification Cataract Extraction for Neovascular Glaucoma Secondary to Proliferative Diabetic Retinopathy with Vitreous Hemorrhage.

To evaluate the clinical efficacy of the combined application of 23G minimally invasive vitrectomy, glaucoma drainage valve implantation, and phacoemulsification cataract extraction in the treatment o... Eighty-three patients (91 eyes) with PDR diagnosed as NVG phase III complicated with VH from June 2018 to May 2020 were selected as the study subjects. The subjects were randomly divided into 3 groups... Through observation, there was no significant difference in the UCVA, IOP, and INV scores in the 3 groups before operation. After the operation, the UCVA, IOP, and INV scores of the 3 groups were sign... 23G minimally invasive vitrectomy, glaucoma drainage valve implantation, and phacoemulsification cataract extraction can effectively improve the UCVA, IOP, and INV scores of NVG secondary to PDR with ...

Time and Motion Studies to assess surgical productivity in cataract theatre lists within the National Health Service: Immediate Sequential Bilateral Cataract Surgery versus Delayed Sequential Bilateral Cataract Surgery.

To compare productivity of National Health Service cataract lists performing unilateral cataract (UC) surgery vs Immediate Sequential Bilateral Cataract Surgery (ISBCS).... Five 4-hour lists with ISBCS cases and five with UC were observed using time and motion studies (TMS). Individual tasks and timings of each staff member in theatre was recorded by two observers. All o... Median number of eyes operated per 4-hour list was 8 (range 6-8) in the ISBCS group and 5 (5-7) in the UC group (p = 0.028). Mean total theatre time (defined as time between the entry of the first pat... Performing consecutive ISBCS cases under LA on routine cataract surgery lists can increase surgical efficiency. TMS are a useful way to investigate surgical productivity and test theoretical models fo...

Comparisons of outcomes and complications of immediate sequential bilateral cataract surgery and unilateral cataract surgery in a tertiary hospital in South Korea.

We investigated the proportions of immediate sequential bilateral cataract surgery (ISBCS) and unilateral cataract surgery during the coronavirus disease 2019 pandemic and compared visual outcomes bet...

Comparative analysis of changes in retinal layer thickness following femtosecond laser-assisted cataract surgery and conventional cataract surgery.

To investigate the influence of femtosecond laser-assisted cataract surgery (FLACS) on macula by examining changes in retinal layers after FLACS and to compare these changes with those after conventio... This study included 113 unrelated Korean patients with age-related cataract who underwent CCS or FLACS in Severance Hospital between September 2019 and July 2021. Optical coherence tomography was perf... Compared with the CCS group, the FLACS group exhibited a thicker ORL (P = 0.004) and a thinner INL (P = 0.007) after surgery. All retinal layer thickness values showed significant postoperative change... The 1-month postoperative retinal changes were less pronounced in the FLACS group than in the CCS group....

Dementia and cataract surgery in Australia and New Zealand.

Cataract surgery improves quality of life and reduces cognitive deterioration.... This paper discusses the health implications of low vision, commonly related to cataracts, in older adults. A recent publication reported that cataract surgery reduces the risk of dementia by 30% over... We searched Medline from inception to January 2023. We also conducted backward and forward citation searches of included studies and set up alerts to identify studies published after the search date. ... This article provides a broad description of the importance of vision for cognitive function. We discuss access to public-funded cataract surgery in Australia and New Zealand and how this impacts popu... We have evidence that cataract surgery can decrease the risk of dementia. This is an important topic that deserves recognition as part of an overall ageing response by policymakers and health professi...

Early intervention for perioperative hypertension in cataract surgery.

Although perioperative blood-pressure control is important, especially for high-risk patients, no previous report has examined early monitoring of perioperative blood-pressure changes before cataract ... Hospitalized patients who underwent phacoemulsification and intraocular-lens insertion and whose blood pressure was controlled using standardized management to start early monitoring and control (stan... Although there was no difference before the operation, the changes in systolic pressure in the standardized group were significantly lower at the point of entering the operation room, at the beginning... Early monitoring and control of blood pressure in cataract surgery could effectively control perioperative hypertension without additional drug use and could be widely applied in the clinical setting....

Spherical Aberration of Astigmatic Corneas in a Cataract Population.

To study the distribution of spherical aberration (SA) in astigmatic corneas in a cataract population and the relationship between magnitude of corneal astigmatism and fourth-order corneal SA.... Data routinely collected using a Scheimpflug camera (Pentacam; Oculus Optikgeräte GmbH) were retrospectively analyzed. Patients with a minimum age of 60 years were included. Total corneal SA (from ant... A total of 528 eyes were included in this analysis. Low astigmatism was found in 129 patients, moderate astigmatism in 265 patients, and high astigmatism in 134 patients. Mean astigmatism was 0.68 ± 0... SA was significantly larger in the cataract population with high corneal astigmatism. The increase of positive sign SA with the magnitude of astigmatism suggests that patients with moderate to high as...

Importance of optical coherence tomography before cataract surgery.

To determine the importance of optical coherence tomography (OCT) in patients scheduled for cataract surgery who present with no pathologies in biomicroscopic fundus examination.... Retrospective study.... In this study, the routine ophthalmologic examination of patients who were recommended cataract surgery was performed.Occult retinal pathologies were evaluated using OCT in patients without any pathol... A total of 271 eyes from 271 patients were evaluated.The number of patients with retinal pathologies on OCT despite normal fundoscopic examination findings was 38(14.0%).Of these patients,15(39.4%) ha... In one of seven patients evaluated, retinal pathologies were detected on OCT despite normal fundoscopic examination findings.OCT can be used to detect occult retinal pathologies that cannot be detecte...