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"description": "Comment le ryanodine est-il utilisé dans le diagnostic médical ?\nQuels tests peuvent impliquer le ryanodine ?\nLe ryanodine aide-t-il à diagnostiquer des maladies spécifiques ?\nQuels marqueurs sont affectés par le ryanodine ?\nLe ryanodine est-il utilisé dans des études cliniques ?",
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"name": "Comment le ryanodine est-il utilisé dans le diagnostic médical ?",
"position": 1,
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"text": "Il est utilisé pour évaluer les dysfonctionnements du calcium dans les muscles."
}
},
{
"@type": "Question",
"name": "Quels tests peuvent impliquer le ryanodine ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de contraction musculaire et des études de flux calcique peuvent être réalisés."
}
},
{
"@type": "Question",
"name": "Le ryanodine aide-t-il à diagnostiquer des maladies spécifiques ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut aider à diagnostiquer des myopathies liées à des anomalies du calcium."
}
},
{
"@type": "Question",
"name": "Quels marqueurs sont affectés par le ryanodine ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il peut influencer les niveaux de calcium intracellulaire et les enzymes musculaires."
}
},
{
"@type": "Question",
"name": "Le ryanodine est-il utilisé dans des études cliniques ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il est utilisé dans des études sur les troubles musculaires et cardiaques."
}
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{
"@type": "Question",
"name": "Quels symptômes sont associés à une dysfonction du ryanodine ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des crampes musculaires, une faiblesse et des douleurs peuvent survenir."
}
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{
"@type": "Question",
"name": "Le ryanodine peut-il provoquer des effets secondaires ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des effets comme des troubles de la contraction musculaire peuvent se produire."
}
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{
"@type": "Question",
"name": "Comment le ryanodine affecte-t-il le cœur ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il peut provoquer des arythmies en modifiant le flux calcique dans les cardiomyocytes."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes neurologiques liés au ryanodine ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des tremblements ou des spasmes peuvent être observés."
}
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{
"@type": "Question",
"name": "Le ryanodine influence-t-il la respiration ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, une dysfonction musculaire peut affecter les muscles respiratoires."
}
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{
"@type": "Question",
"name": "Comment prévenir les effets indésirables du ryanodine ?",
"position": 11,
"acceptedAnswer": {
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"text": "Une surveillance médicale régulière et un ajustement de la dose sont essentiels."
}
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{
"@type": "Question",
"name": "Y a-t-il des recommandations alimentaires pour les utilisateurs de ryanodine ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée en calcium et en électrolytes est recommandée."
}
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{
"@type": "Question",
"name": "Les patients doivent-ils éviter certains médicaments avec le ryanodine ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, éviter les médicaments qui affectent le calcium sans avis médical."
}
},
{
"@type": "Question",
"name": "Comment évaluer le risque d'effets secondaires ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests réguliers de la fonction musculaire et cardiaque sont conseillés."
}
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{
"@type": "Question",
"name": "Le suivi médical est-il important lors de l'utilisation du ryanodine ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier permet de détecter rapidement les complications."
}
},
{
"@type": "Question",
"name": "Comment le ryanodine est-il utilisé en traitement ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est utilisé pour traiter certaines myopathies et troubles du calcium."
}
},
{
"@type": "Question",
"name": "Le ryanodine est-il administré par voie orale ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, il est généralement administré par injection ou perfusion intraveineuse."
}
},
{
"@type": "Question",
"name": "Quels médicaments interagissent avec le ryanodine ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments affectant le calcium, comme les bloqueurs des canaux calciques, peuvent interagir."
}
},
{
"@type": "Question",
"name": "Le ryanodine est-il utilisé en anesthésie ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut être utilisé pour prévenir des complications musculaires pendant l'anesthésie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des alternatives au ryanodine ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, d'autres agents modulant le calcium peuvent être utilisés selon les besoins."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le ryanodine ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des arythmies et des troubles musculaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Le ryanodine peut-il causer des dommages permanents ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dommages permanents sont rares mais possibles en cas d'utilisation prolongée."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications liées au ryanodine ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une intervention médicale rapide et un ajustement du traitement sont nécessaires."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles prévisibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être prévisibles avec une surveillance adéquate."
}
},
{
"@type": "Question",
"name": "Le ryanodine peut-il interagir avec d'autres traitements ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des interactions avec d'autres traitements peuvent augmenter le risque de complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque liés au ryanodine ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents de troubles musculaires et cardiaques augmentent les risques."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il les risques associés au ryanodine ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées peuvent être plus sensibles aux effets du ryanodine."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques au ryanodine ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines conditions génétiques peuvent augmenter la sensibilité au ryanodine."
}
},
{
"@type": "Question",
"name": "Les habitudes de vie affectent-elles les risques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des habitudes comme le tabagisme ou l'alcool peuvent augmenter les risques."
}
},
{
"@type": "Question",
"name": "Les interactions médicamenteuses sont-elles un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines interactions peuvent exacerber les effets indésirables du ryanodine."
}
}
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To empirically assign severity levels (e.g., mild, moderate) to four relatively new patient-reported outcome measures (PROMs) for adults with acquired cognitive/language disorders. They include the Co...
We conducted 17 focus groups that comprised 22 adults with an acquired cognitive/language disorder from stroke, Parkinson's disease, or traumatic brain injury; 30 care partners of an adult with an acq...
There was generally good agreement among the stakeholder groups about how to classify vignettes, particularly when they reflected very high or low functioning. People with aphasia described a larger r...
Standardized, stakeholder-informed severity levels that aid interpretation of PROM scores can help clinicians and researchers derive better clinical meaning from those scores, for example, by identify...
A major barrier to the wider use of language sample analysis (LSA) is the fact that transcription is very time intensive. Methods that can reduce the required time and effort could help in promoting t...
This article describes an automated pipeline, called Batchalign, that takes raw audio and creates full transcripts in Codes for the Human Analysis of Talk (CHAT) transcription format, complete with ut...
For work with recordings from adults with language disorders, six major results were obtained: (a) The word error rate was between 2.4% for controls and 3.4% for patients, (b) utterance tokenization a...
The pipeline dramatically shortens the time gap between data collection and data analysis and provides an output superior to that typically generated by human transcribers....
It has been well-documented that language input designed according to the principles of statistical learning can promote language acquisition among children with or without language disorder. Cantones...
The purpose of this study was to compare child language assessment practices of speech-language pathologists (SLPs) working in school and nonschool settings to determine if their place of employment i...
School-based SLPs (e.g., direct service providers employed in preschool and/or K-12 schools;...
Both school-based and non-school-based SLPs reported using a combination of assessment tools when evaluating children with potential language disorders. School-based SLPs tended to rank the frequency ...
SLPs practicing in school-based settings seem to handle more employment-based factors that impact independent diagnostic decision making than SLPs working in different employment settings when assessi...
Language production has often been described as impaired in psychiatric diseases such as in psychosis. Nevertheless, little is known about the characteristics of linguistic difficulties and their rela...
To date, cerebellar contribution to language is well established via clinical and neuroimaging studies. However, the particular functional role of the cerebellum in language remains to be clarified. I...
The authors applied natural language processing and machine learning to explore the disease-related language patterns that warrant objective measures for assessing language ability in Japanese patient...
The authors obtained 276 speech samples from 42 patients with AD and 52 healthy controls, aged 50 years or older. A natural language processing library for Python was used, spaCy, with an add-on libra...
The model resulted in an accuracy of 0.84 (SD = 0.06), and an area under the curve of 0.90 (SD = 0.03). Among the features that were important for such predictions, seven of the top 10 features were r...
The current study demonstrated a promising level of accuracy for predicting AD and found the language patterns corresponding to the type of lexical-semantic decline known as 'empty speech', which is r...
Language sample analysis (LSA) is invaluable to describe and understand child language use and development for clinical purposes and research. Digital tools supporting LSA are available, but many of t...
To better understand the complexity, challenges, and future needs of automatic LSA from a technological perspective, including the tasks of transcribing, annotating, and analysing natural child langua...
Existing tools vary in their extent of automation provided across the process of LSA. Advances in machine learning for speech recognition and processing have potential to facilitate LSA, but the speci...
Syntax has been called the structural foundation of language, as its development allows for more efficient and effective communication. Complex syntax production is known to lag in children and adoles...
Conversational, narrative, and expository language samples were elicited from 85 children with typically developing language ages 8;0-11;11 (years;months). Samples were transcribed and analyzed for th...
Syntactic measures differed significantly across the three sampling contexts. Namely, narrative and expository language samples elicited longer utterances and more syntactically complex language than ...
Differences in syntactic measures between conversation and narrative samples and conversation and expository samples within children ages 8-11 years support use of narrative and expository contexts as...
Acquired central dysgraphia is a heterogeneous neurological disorder that usually co-occurs with other language disorders. Written language training is relevant to improve everyday skills and as a com...
We performed a systematic review of speech and language therapies for acquired dysgraphia in studies of neurological diseases (PROSPERO: CRD42018084221), following the PRISMA (Preferred Reporting Item...
Eleven studies of 43 patients in total were included. For each study, we collected data on type of population, type of impairment, experimental design, type of treatment, and measured outcomes. The st...
Although there is a need for further experimental evidence, most treatments showed good applicability and improvement of written skills in patients with dysgraphia. Lexical treatments appear to be mor...
