Titre : Malformations cutanées

Malformations cutanées : Questions médicales fréquentes

Termes MeSH sélectionnés :

Prostatic Neoplasms
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familiaux influencent-ils le diagnostic ?\nLes malformations cutanées sont-elles toujours visibles à la naissance ?\nQuel rôle joue l'examen dermatologique ?", "url": "https://questionsmedicales.fr/mesh/D012868?mesh_terms=Prostatic+Neoplasms&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Malformations cutanées", "description": "Quels sont les symptômes courants des malformations cutanées ?\nLes malformations cutanées causent-elles des douleurs ?\nPeut-on avoir des démangeaisons avec des malformations cutanées ?\nLes malformations cutanées affectent-elles la fonction de la peau ?\nY a-t-il des signes d'infection associés ?", "url": "https://questionsmedicales.fr/mesh/D012868?mesh_terms=Prostatic+Neoplasms&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Malformations cutanées", "description": "Peut-on prévenir les malformations cutanées ?\nLes facteurs environnementaux jouent-ils un rôle ?\nL'alimentation influence-t-elle les malformations cutanées ?\nLes vaccinations peuvent-elles aider ?\nLe suivi médical est-il important ?", "url": "https://questionsmedicales.fr/mesh/D012868?mesh_terms=Prostatic+Neoplasms&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Malformations cutanées", "description": "Quels traitements sont disponibles pour les malformations cutanées ?\nLa chirurgie est-elle toujours nécessaire ?\nLes traitements topiques sont-ils efficaces ?\nLes traitements varient-ils selon l'âge ?\nY a-t-il des traitements non invasifs ?", "url": "https://questionsmedicales.fr/mesh/D012868?mesh_terms=Prostatic+Neoplasms&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Malformations cutanées", "description": "Quelles complications peuvent survenir ?\nLes malformations cutanées peuvent-elles entraîner des cancers ?\nComment les malformations affectent-elles la qualité de vie ?\nLes malformations cutanées peuvent-elles causer des infections ?\nY a-t-il des complications liées aux traitements ?", "url": "https://questionsmedicales.fr/mesh/D012868?mesh_terms=Prostatic+Neoplasms&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Malformations cutanées", "description": "Quels sont les facteurs de risque génétiques ?\nL'exposition à des toxines augmente-t-elle le risque ?\nLe tabagisme est-il un facteur de risque ?\nLes infections maternelles influencent-elles le risque ?\nL'âge maternel joue-t-il un rôle ?", "url": "https://questionsmedicales.fr/mesh/D012868?mesh_terms=Prostatic+Neoplasms&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une malformation cutanée ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur l'examen clinique et parfois des biopsies cutanées." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour les malformations cutanées ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests d'imagerie et des analyses histologiques peuvent être nécessaires." } }, { "@type": "Question", "name": "Les antécédents familiaux influencent-ils le diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents familiaux peuvent indiquer une prédisposition génétique." } }, { "@type": "Question", "name": "Les malformations cutanées sont-elles toujours visibles à la naissance ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Non, certaines peuvent se développer avec le temps et ne pas être visibles à la naissance." } }, { "@type": "Question", "name": "Quel rôle joue l'examen dermatologique ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'examen dermatologique est crucial pour évaluer l'étendue et la nature des anomalies." } }, { "@type": "Question", "name": "Quels sont les symptômes courants des malformations cutanées ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des lésions, des décolorations et des anomalies de texture." } }, { "@type": "Question", "name": "Les malformations cutanées causent-elles des douleurs ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Certaines malformations peuvent être douloureuses, surtout si elles sont irritées." } }, { "@type": "Question", "name": "Peut-on avoir des démangeaisons avec des malformations cutanées ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des démangeaisons peuvent survenir, surtout avec des lésions inflammatoires." } }, { "@type": "Question", "name": "Les malformations cutanées affectent-elles la fonction de la peau ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent affecter la fonction protectrice de la peau, augmentant le risque d'infections." } }, { "@type": "Question", "name": "Y a-t-il des signes d'infection associés ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, rougeur, chaleur et écoulement peuvent indiquer une infection secondaire." } }, { "@type": "Question", "name": "Peut-on prévenir les malformations cutanées ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Certaines malformations peuvent être évitées par des soins prénatals appropriés." } }, { "@type": "Question", "name": "Les facteurs environnementaux jouent-ils un rôle ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à certains agents environnementaux peut augmenter le risque." } }, { "@type": "Question", "name": "L'alimentation influence-t-elle les malformations cutanées ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée pendant la grossesse peut réduire certains risques." } }, { "@type": "Question", "name": "Les vaccinations peuvent-elles aider ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Certaines vaccinations peuvent prévenir des infections qui aggravent les malformations." } }, { "@type": "Question", "name": "Le suivi médical est-il important ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un suivi médical régulier peut aider à détecter précocement les anomalies." } }, { "@type": "Question", "name": "Quels traitements sont disponibles pour les malformations cutanées ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements varient de la surveillance à la chirurgie, selon la gravité." } }, { "@type": "Question", "name": "La chirurgie est-elle toujours nécessaire ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Non, la chirurgie est réservée aux cas graves ou esthétiquement préoccupants." } }, { "@type": "Question", "name": "Les traitements topiques sont-ils efficaces ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains traitements topiques peuvent aider à réduire les symptômes." } }, { "@type": "Question", "name": "Les traitements varient-ils selon l'âge ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les options de traitement peuvent différer selon l'âge du patient." } }, { "@type": "Question", "name": "Y a-t-il des traitements non invasifs ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des traitements comme la thérapie au laser peuvent être non invasifs." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des infections, des cicatrices et des problèmes psychologiques." } }, { "@type": "Question", "name": "Les malformations cutanées peuvent-elles entraîner des cancers ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Certaines malformations peuvent avoir un risque accru de développer des cancers cutanés." } }, { "@type": "Question", "name": "Comment les malformations affectent-elles la qualité de vie ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent affecter l'estime de soi et entraîner des problèmes sociaux ou psychologiques." } }, { "@type": "Question", "name": "Les malformations cutanées peuvent-elles causer des infections ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les lésions cutanées peuvent être une porte d'entrée pour des infections bactériennes." } }, { "@type": "Question", "name": "Y a-t-il des complications liées aux traitements ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains traitements peuvent entraîner des effets secondaires ou des complications." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque génétiques ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Des antécédents familiaux de malformations cutanées augmentent le risque." } }, { "@type": "Question", "name": "L'exposition à des toxines augmente-t-elle le risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à des toxines pendant la grossesse peut augmenter le risque." } }, { "@type": "Question", "name": "Le tabagisme est-il un facteur de risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le tabagisme pendant la grossesse est associé à des malformations cutanées." } }, { "@type": "Question", "name": "Les infections maternelles influencent-elles le risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections maternelles peuvent augmenter le risque de malformations cutanées." } }, { "@type": "Question", "name": "L'âge maternel joue-t-il un rôle ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un âge maternel avancé est associé à un risque accru de malformations." } } ] } ] }

Sources (10000 au total)

Prostate and metastasis-directed focal therapy in prostate cancer: hype or hope?

The paradigm of focal therapy's role in metastatic patients is being challenged by evolving attitudes and emerging data. At the current time, specifically regarding prostate cancer, does the evidence ... We searched the literature via PubMed, MEDLINE, and Embase for studies from 2014 to the present addressing focal therapy with non-palliative intent in metastatic prostate cancer patients, emphasizing ... Current evidence is strongest, and in our opinion practice-changing, for prostate-directed RT in de novo metastatic patients with low metastatic burden. Metastasis-directed therapy with SBRT is consis...

Development and evaluation of the MiCheck® Prostate test for clinically significant prostate cancer.

There is a clinical need to identify patients with an elevated PSA who would benefit from prostate biopsy due to the presence of clinically significant prostate cancer (CSCaP). We have previously repo... To further develop and adapt the MiCheck® Prostate test so it can be performed using a standard clinical chemistry analyzer and characterize its performance using the MiCheck-01 clinical trial sample ... About 358 patient samples from the MiCheck-01 US clinical trial were used for the development of the MiCheck® Prostate test. These consisted of 46 controls, 137 non-CaP, 62 non-CSCaP, and 113 CSCaP.... Serum analyte concentrations for cellular growth factors were determined using custom-made Luminex-based R&D Systems multi-analyte kits. Analytes that can also be measured using standard chemistry ana... Logistic regression modeling with Monte Carlo cross-validation was used to identify Human Epidydimal Protein 4 (HE4) as an analyte able to significantly improve the algorithm specificity at 95% sensit... The MiCheck® logistic regression model was developed and consisted of PSA, %free PSA, DRE, and HE4. The model differentiated clinically significant cancer from no cancer or not-clinically significant ... The MiCheck® Prostate test identifies clinically significant prostate cancer with high sensitivity and negative predictive value (NPV). It can be performed in a clinical laboratory using a Roche Cobas...

New strategy for the identification of prostate cancer: The combination of Proclarix and the prostate health index.

Prostate health index (PHI) and, more recently, Proclarix have been proposed as serum biomarkers for prostate cancer (PCa). In this study, we aimed to evaluate Proclarix and PHI for predicting clinica... Proclarix and PHI were measured using samples of 344 men from two different centers. All patients underwent prostate biopsy, and among those, 188 men with PCa on biopsy had an additional radical prost... The cohort median age and PSA were 65 (interquartile range [IQR]: 60-71) and 5.6 (IQR: 4.3-7.2) ng/ml, respectively. CsPCa was diagnosed in 161 (47%) men based on the RP specimen. ROC analysis showed ... Results of this study show that both Proclarix and PHI accurately detect the presence of csPCa. The model combining Proclarix and PHI revealed the synergistic effect and improved the diagnostic perfor...

Detection of clinically significant prostate cancer by transperineal multiparametric magnetic resonance imaging-ultrasound fusion targeted prostate biopsy in smaller prostates.

Transperineal (TP) multiparametric magnetic resonance imaging (mpMRI)-targeted biopsy (TBx) has been shown to detect more clinically significant (cs) prostate cancer (PCa) than standard template biops... We identified all men who with suspicious lesions on mpMRI and underwent TP TBx (3-core) and concomitant SBx (20-core) in our single hospital from September 2019 to February 2021. Clinical, MRI and bi... Three hundred and one (n = 301) men were included. The median prostate volume by MRI was 45 ml. The patients were divided by prostate volume into three groups: ≤30ml group (19.9%), >30 to ≤45 ml group... Our data suggest that performing TBx with limited additional cores may potentially achieve the same csPCa detection rate as the combined SBx and TBx in smaller prostates....

Are elevated mitochondrial DNA fragments in prostatic inflammation a potential biomarker for prostate cancer?

We sought to determine whether two soluble forms with different size of mtDNA are linked to prostatic inflammation, and whether they discriminate prostate cancer (PCa) from inflammatory prostatic cond... Histopathologically diagnosed prostatitis, PCa and benign prostatic hyperplasia patients (n = 93) were enrolled in this study and they were categorized as with and without prostate inflammation. Quant... The urine mtDNA-79 and mtDNA-230 were significantly increased in patients with prostate inflammation compared with those in without inflammation. Here, 79-bp fragment of apoptotic origin was significa... Our results demonstrate that shorter cf-mtDNA fragment size in particular, increase in the presence of prostate inflammation in post-prostatic massage urine but both fragments could never improve seru...

The rapid assessment for prostate imaging and diagnosis (RAPID) prostate cancer diagnostic pathway.

To report outcomes within the Rapid Assessment for Prostate Imaging and Diagnosis (RAPID) diagnostic pathway, introduced to reduce patient and healthcare burdens and standardize delivery of pre-biopsy... A total of 2130 patients from three centres who completed the RAPID pathway (3 April 2017 to 31 March 2020) were consecutively entered as a prospective registry. These patients were also compared to a... The median patient age and PSA level were 66 years and 6.6 ng/mL, respectively. Biopsy could be omitted in 43% of patients (920/2130). A further 7.9% of patients (168/2130) declined a recommendation f... The RAPID prostate cancer diagnostic pathway allows 43% of men to avoid a biopsy while preserving good detection of clinically significant cancers and low detection of insignificant cancers, although ...