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"name": "Diagnostic",
"headline": "Diagnostic sur Philadelphie",
"description": "Comment diagnostiquer la leucémie myéloïde chronique ?\nQuels tests sont utilisés pour confirmer la présence du chromosome de Philadelphie ?\nQuels signes cliniques indiquent une LMC ?\nQuel rôle joue l'hémogramme dans le diagnostic ?\nQuand faut-il suspecter une LMC ?",
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"name": "Symptômes",
"headline": "Symptômes sur Philadelphie",
"description": "Quels sont les symptômes courants de la LMC ?\nLa splénomégalie est-elle un symptôme de la LMC ?\nLes sueurs nocturnes sont-elles liées à la LMC ?\nComment la LMC affecte-t-elle l'énergie du patient ?\nLes infections fréquentes sont-elles un symptôme de la LMC ?",
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"name": "Prévention",
"headline": "Prévention sur Philadelphie",
"description": "Peut-on prévenir la LMC ?\nQuels facteurs de risque sont associés à la LMC ?\nLe tabagisme influence-t-il le risque de LMC ?\nLes antécédents familiaux jouent-ils un rôle ?\nComment réduire le risque de LMC ?",
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"name": "Traitements",
"headline": "Traitements sur Philadelphie",
"description": "Quels traitements sont disponibles pour la LMC ?\nQuel est le rôle des inhibiteurs de tyrosine kinase ?\nLa greffe de moelle osseuse est-elle une option ?\nQuels effets secondaires peuvent survenir avec le traitement ?\nComment surveiller l'efficacité du traitement ?",
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"headline": "Complications sur Philadelphie",
"description": "Quelles complications peuvent survenir avec la LMC ?\nQu'est-ce qu'une crise blastique ?\nLa résistance au traitement est-elle une complication ?\nComment les complications affectent-elles le pronostic ?\nLes complications peuvent-elles être gérées ?",
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"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Philadelphie",
"description": "Quels sont les principaux facteurs de risque de la LMC ?\nL'âge influence-t-il le risque de LMC ?\nLes maladies génétiques augmentent-elles le risque ?\nLe sexe joue-t-il un rôle dans le risque de LMC ?\nLes infections virales sont-elles un facteur de risque ?",
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"name": "Comment diagnostiquer la leucémie myéloïde chronique ?",
"position": 1,
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"text": "Le diagnostic se fait par un test sanguin et une analyse cytogénétique pour détecter le chromosome de Philadelphie."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour confirmer la présence du chromosome de Philadelphie ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests de fluorescence in situ hybridation (FISH) et la PCR sont utilisés."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques indiquent une LMC ?",
"position": 3,
"acceptedAnswer": {
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"text": "Fatigue, perte de poids, sueurs nocturnes et splénomégalie sont des signes courants."
}
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"@type": "Question",
"name": "Quel rôle joue l'hémogramme dans le diagnostic ?",
"position": 4,
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"text": "L'hémogramme révèle une augmentation des globules blancs, un indicateur clé de la LMC."
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"name": "Quand faut-il suspecter une LMC ?",
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{
"@type": "Question",
"name": "Quels sont les symptômes courants de la LMC ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent fatigue, fièvre, douleurs osseuses et saignements fréquents."
}
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{
"@type": "Question",
"name": "La splénomégalie est-elle un symptôme de la LMC ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la splénomégalie est fréquente et peut causer des douleurs abdominales."
}
},
{
"@type": "Question",
"name": "Les sueurs nocturnes sont-elles liées à la LMC ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les sueurs nocturnes sont un symptôme courant chez les patients atteints de LMC."
}
},
{
"@type": "Question",
"name": "Comment la LMC affecte-t-elle l'énergie du patient ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients peuvent ressentir une fatigue intense due à l'anémie et à la maladie elle-même."
}
},
{
"@type": "Question",
"name": "Les infections fréquentes sont-elles un symptôme de la LMC ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections fréquentes peuvent survenir en raison d'une immunité affaiblie."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir la LMC ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de méthode de prévention spécifique pour la LMC, car elle est souvent liée à des facteurs génétiques."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque sont associés à la LMC ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition aux radiations et certains produits chimiques augmentent le risque de LMC."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il le risque de LMC ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme est un facteur de risque potentiel, bien que moins étudié que d'autres facteurs."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de cancers hématologiques peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Comment réduire le risque de LMC ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter l'exposition aux produits chimiques nocifs et aux radiations peut aider à réduire le risque."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour la LMC ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent les inhibiteurs de tyrosine kinase, la chimiothérapie et la greffe de moelle."
}
},
{
"@type": "Question",
"name": "Quel est le rôle des inhibiteurs de tyrosine kinase ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils ciblent spécifiquement les cellules cancéreuses et bloquent leur croissance."
}
},
{
"@type": "Question",
"name": "La greffe de moelle osseuse est-elle une option ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la greffe peut être envisagée pour les cas avancés ou résistants au traitement."
}
},
{
"@type": "Question",
"name": "Quels effets secondaires peuvent survenir avec le traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires incluent nausées, fatigue, et risque accru d'infections."
}
},
{
"@type": "Question",
"name": "Comment surveiller l'efficacité du traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins réguliers et des examens de suivi sont nécessaires pour évaluer la réponse."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec la LMC ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections, des saignements et des crises blastiques."
}
},
{
"@type": "Question",
"name": "Qu'est-ce qu'une crise blastique ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "C'est une progression de la LMC vers une forme plus agressive, ressemblant à une leucémie aiguë."
}
},
{
"@type": "Question",
"name": "La résistance au traitement est-elle une complication ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains patients peuvent développer une résistance aux inhibiteurs de tyrosine kinase."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles le pronostic ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications peuvent aggraver le pronostic et nécessiter des traitements plus intensifs."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être gérées ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la gestion des complications est essentielle pour améliorer la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque de la LMC ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition aux radiations, certains produits chimiques et des antécédents familiaux sont des facteurs clés."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque de LMC ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la LMC est plus fréquente chez les adultes âgés de 50 à 70 ans."
}
},
{
"@type": "Question",
"name": "Les maladies génétiques augmentent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies génétiques, comme le syndrome de Down, peuvent augmenter le risque de LMC."
}
},
{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le risque de LMC ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les hommes sont légèrement plus susceptibles de développer la LMC que les femmes."
}
},
{
"@type": "Question",
"name": "Les infections virales sont-elles un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales, comme le virus d'Epstein-Barr, peuvent être associées à un risque accru."
}
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Children with autism spectrum disorders (ASD) usually experience difficulty regarding symbolic play. However, studies on whether symbolic play test (SPT) can differentiate between ASD and other develo...
A total of 200 children were selected as the research participants. There were 100 cases of ASD without GDD and 100 cases of DLD. All children were tested by SPT and Children Neuropsychological and Be...
SPT equivalent age was lower than chronological age in the two groups, the difference between the ASD without GDD group was greater than that in the DLD group, and the proportion of SPT equivalent age...
Symbolic play ability in ASD children is worse than that of DLD children at comparable development levels. SPT may be helpful to distinguish ASD without GDD from children with DLD....
Verb-marking errors are a characteristic feature of the speech of typically-developing (TD) children and are particularly prevalent in the speech of children with Developmental Language Disorder (DLD)...
Children with Developmental Language Disorder (DLD) have difficult access to social interactions, which could in turn limit their opportunities to learn about others' emotions....
This study aimed to investigate the developmental trajectories of emotion understanding in young children with and without DLD....
95 DLD children and 149 non-DLD children were tested twice, with an approximately two-year interval (M...
At Time 2, DLD children fell behind their non-DLD peers on the non-verbal task for emotion discrimination, while catching up on the verbal tasks for emotion identification and attribution. The two gro...
The findings showed the potential of DLD children to understand others' emotions in verbal tasks to a similar extent as their non-DLD peers. However, DLD children may still face difficulties understan...
The purpose of this study is to examine the feasibility of the delivery of complex syntax recast therapy via telepractice to Spanish-English bilingual children and provide preliminary evidence of the ...
Fifteen bilingual children with developmental language disorders were stratified based on language proficiency and randomized to one of three treatment conditions: Spanish only (...
Analyses included all participants. Treatment fidelity was high, and participant attendance was remarkable, indicating feasibility. Regarding efficacy, recast therapy led to group-level gains on treat...
Preliminary evidence suggests that for highly overlapping structures like conditional adverbials, recast therapy is effective and leads to change in both of the child's languages. Larger studies are r...
https://doi.org/10.23641/asha.23739996....
Developmental language disorder (DLD) is one of the most common neurodevelopmental disorders. The influences of DLD on language development have been delineated in detail in English. The same is not t...
This study aimed to find the association of receptive vocabulary in the development of speech and language among school-going children (4-13 years) with language disorders. On the basis of non-verbal ...
In recent years, there have been intense international discussions about the definition and terminology of language disorders in childhood, such as those sparked by the publications of the CATALISE co...
Narrative assessment is one potentially underutilized and inconsistent method speech-language pathologists may use when considering a diagnosis of developmental language disorder (DLD). However, narra...
Electronic databases (PsycINFO, ERIC, and PubMed) and ASHAWire were searched on July 30, 2019, to locate studies that reported oral narrative language measures for both DLD and TD groups between ages ...
Searches identified 37 eligible studies published between 1987 and 2019, including 382 effect sizes. Overall meta-analysis showed that children with DLD had decreased narrative performance relative to...
Present findings suggest some narrative assessment measures yield significantly different performance between children with and without DLD. However, researchers need to improve consistency of inclusi...
https://doi.org/10.23641/asha.21200380....
Children with a developmental language disorder (DLD) are often delayed in their grammatical development. This is suggested to be the most important characteristic and clinical marker of DLD. However,...
Language samples of 59 children (29 children with DLD and 30 TD children) were analyzed using multiple measures of grammatical complexity, diversity, and accuracy. The TD children and children with DL...
The results show that children with DLD are comparable to language-matched TD children in their grammatical accuracy and diversity, but that they produce less complex utterances....
The results indicate that children with DLD lag behind in their grammatical complexity as compared to language-matched TD children. The results also suggest that grammatical TARSP level is not suffici...
This study sought to determine the prevalence of Developmental Language Disorder (DLD) in Australian school-aged children and associated potential risk factors for DLD at 10 years....
This study used a cross-sectional design to estimate the prevalence of DLD in Generation 2 of the prospective Raine Study. Participants included 1626 children aged 10 years with available language dat...
The prevalence of DLD in this sample was 6.4% (n = 104) at 10 years. This sub-cohort comprised 33.7% (n = 35) with expressive language deficits, 20.2% (n = 21) with receptive language deficits, and 46...
DLD is a relatively prevalent condition in Australian children, even when assessed in middle childhood years. These findings can inform future research priorities, and public health and educational po...