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"description": "Comment diagnostiquer la leucémie myéloïde chronique ?\nQuels tests sont utilisés pour confirmer la présence du chromosome de Philadelphie ?\nQuels signes cliniques indiquent une LMC ?\nQuel rôle joue l'hémogramme dans le diagnostic ?\nQuand faut-il suspecter une LMC ?",
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"name": "Comment diagnostiquer la leucémie myéloïde chronique ?",
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"text": "Le diagnostic se fait par un test sanguin et une analyse cytogénétique pour détecter le chromosome de Philadelphie."
}
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour confirmer la présence du chromosome de Philadelphie ?",
"position": 2,
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"text": "Les tests de fluorescence in situ hybridation (FISH) et la PCR sont utilisés."
}
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"@type": "Question",
"name": "Quels signes cliniques indiquent une LMC ?",
"position": 3,
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"text": "Fatigue, perte de poids, sueurs nocturnes et splénomégalie sont des signes courants."
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"@type": "Question",
"name": "Quel rôle joue l'hémogramme dans le diagnostic ?",
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"name": "Quels sont les symptômes courants de la LMC ?",
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"text": "Les symptômes incluent fatigue, fièvre, douleurs osseuses et saignements fréquents."
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"@type": "Question",
"name": "La splénomégalie est-elle un symptôme de la LMC ?",
"position": 7,
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"text": "Oui, la splénomégalie est fréquente et peut causer des douleurs abdominales."
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"@type": "Question",
"name": "Les sueurs nocturnes sont-elles liées à la LMC ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, les sueurs nocturnes sont un symptôme courant chez les patients atteints de LMC."
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"name": "Comment la LMC affecte-t-elle l'énergie du patient ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients peuvent ressentir une fatigue intense due à l'anémie et à la maladie elle-même."
}
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{
"@type": "Question",
"name": "Les infections fréquentes sont-elles un symptôme de la LMC ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, les infections fréquentes peuvent survenir en raison d'une immunité affaiblie."
}
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{
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"name": "Peut-on prévenir la LMC ?",
"position": 11,
"acceptedAnswer": {
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"text": "Il n'existe pas de méthode de prévention spécifique pour la LMC, car elle est souvent liée à des facteurs génétiques."
}
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{
"@type": "Question",
"name": "Quels facteurs de risque sont associés à la LMC ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition aux radiations et certains produits chimiques augmentent le risque de LMC."
}
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{
"@type": "Question",
"name": "Le tabagisme influence-t-il le risque de LMC ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme est un facteur de risque potentiel, bien que moins étudié que d'autres facteurs."
}
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{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de cancers hématologiques peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Comment réduire le risque de LMC ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter l'exposition aux produits chimiques nocifs et aux radiations peut aider à réduire le risque."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour la LMC ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent les inhibiteurs de tyrosine kinase, la chimiothérapie et la greffe de moelle."
}
},
{
"@type": "Question",
"name": "Quel est le rôle des inhibiteurs de tyrosine kinase ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils ciblent spécifiquement les cellules cancéreuses et bloquent leur croissance."
}
},
{
"@type": "Question",
"name": "La greffe de moelle osseuse est-elle une option ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la greffe peut être envisagée pour les cas avancés ou résistants au traitement."
}
},
{
"@type": "Question",
"name": "Quels effets secondaires peuvent survenir avec le traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires incluent nausées, fatigue, et risque accru d'infections."
}
},
{
"@type": "Question",
"name": "Comment surveiller l'efficacité du traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins réguliers et des examens de suivi sont nécessaires pour évaluer la réponse."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec la LMC ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections, des saignements et des crises blastiques."
}
},
{
"@type": "Question",
"name": "Qu'est-ce qu'une crise blastique ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "C'est une progression de la LMC vers une forme plus agressive, ressemblant à une leucémie aiguë."
}
},
{
"@type": "Question",
"name": "La résistance au traitement est-elle une complication ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains patients peuvent développer une résistance aux inhibiteurs de tyrosine kinase."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles le pronostic ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications peuvent aggraver le pronostic et nécessiter des traitements plus intensifs."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être gérées ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la gestion des complications est essentielle pour améliorer la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque de la LMC ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition aux radiations, certains produits chimiques et des antécédents familiaux sont des facteurs clés."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque de LMC ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la LMC est plus fréquente chez les adultes âgés de 50 à 70 ans."
}
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{
"@type": "Question",
"name": "Les maladies génétiques augmentent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies génétiques, comme le syndrome de Down, peuvent augmenter le risque de LMC."
}
},
{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le risque de LMC ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les hommes sont légèrement plus susceptibles de développer la LMC que les femmes."
}
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"@type": "Question",
"name": "Les infections virales sont-elles un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales, comme le virus d'Epstein-Barr, peuvent être associées à un risque accru."
}
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Plant specialized metabolites (PSMs) are variably distributed across taxa, tissues, and ecological contexts; this variability has inspired many theories about PSM function, which to-date remain poorly...
Orthostatic tremor is a rare movement disorder characterized by a sensation of unsteadiness and leg tremor while standing. It has been hypothesized that the disorder is attributable to dysregulation o...
Major burn injury, despite advancements in care and prevention, can have a profound impact on long-term morbidity, affecting quality of life and socioeconomic standing. We aim to explore factors predi...
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Over the years, there have been increasing reports of the (re)localization of PDI family members and other ER-localized proteins to various compartments. A prime example is the Anterior gradient (AGR)...
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