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"description": "Comment diagnostiquer l'exposition au MPP+ ?\nQuels examens sont recommandés pour le MPP+ ?\nQuels symptômes indiquent une intoxication au MPP+ ?\nLe MPP+ peut-il être détecté dans le sang ?\nQuels tests neurologiques sont utiles pour le MPP+ ?",
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"description": "Quels traitements sont efficaces contre le MPP+ ?\nLa réhabilitation est-elle utile pour les patients exposés au MPP+ ?\nPeut-on utiliser des antioxydants pour traiter le MPP+ ?\nLes thérapies complémentaires sont-elles bénéfiques ?\nLe traitement précoce du MPP+ est-il crucial ?",
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"description": "Quelles complications peuvent survenir avec le MPP+ ?\nLe MPP+ peut-il entraîner des chutes ?\nY a-t-il un risque accru de dépression avec le MPP+ ?\nLe MPP+ peut-il affecter la qualité de vie ?\nDes complications cardiovasculaires sont-elles possibles ?",
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"headline": "Facteurs de risque sur 1-Méthyl-4-phényl-pyridinium",
"description": "Quels sont les principaux facteurs de risque du MPP+ ?\nL'âge est-il un facteur de risque pour le MPP+ ?\nLes antécédents familiaux influencent-ils le risque ?\nLe sexe joue-t-il un rôle dans le risque de MPP+ ?\nLe mode de vie influence-t-il le risque de MPP+ ?",
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"@type": "Question",
"name": "Comment diagnostiquer l'exposition au MPP+ ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests biologiques et des évaluations neurologiques sont utilisés pour diagnostiquer l'exposition."
}
},
{
"@type": "Question",
"name": "Quels examens sont recommandés pour le MPP+ ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IRM et l'électromyographie peuvent aider à évaluer les dommages neurologiques."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une intoxication au MPP+ ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tremblements, rigidité et bradykinésie peuvent indiquer une intoxication au MPP+."
}
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{
"@type": "Question",
"name": "Le MPP+ peut-il être détecté dans le sang ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des analyses sanguines peuvent détecter la présence de MPP+."
}
},
{
"@type": "Question",
"name": "Quels tests neurologiques sont utiles pour le MPP+ ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de coordination et de réflexes peuvent évaluer l'impact neurologique du MPP+."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes principaux du MPP+ ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent tremblements, rigidité musculaire et troubles de la marche."
}
},
{
"@type": "Question",
"name": "Le MPP+ cause-t-il des troubles cognitifs ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition au MPP+ peut entraîner des troubles cognitifs et de la mémoire."
}
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{
"@type": "Question",
"name": "Y a-t-il des symptômes non moteurs liés au MPP+ ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des symptômes comme la dépression et l'anxiété peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment le MPP+ affecte-t-il le système nerveux ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le MPP+ endommage les neurones dopaminergiques, entraînant des symptômes parkinsoniens."
}
},
{
"@type": "Question",
"name": "Le MPP+ provoque-t-il des douleurs ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs musculaires et articulaires peuvent être présentes chez les patients."
}
},
{
"@type": "Question",
"name": "Comment prévenir l'exposition au MPP+ ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les environnements contaminés et utiliser des équipements de protection."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccins contre le MPP+ ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de vaccin spécifique contre le MPP+."
}
},
{
"@type": "Question",
"name": "Les changements de mode de vie aident-ils à prévenir le MPP+ ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sain peut réduire le risque de maladies neurodégénératives."
}
},
{
"@type": "Question",
"name": "L'éducation sur le MPP+ est-elle importante ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'éducation sur les risques et les symptômes est essentielle pour la prévention."
}
},
{
"@type": "Question",
"name": "Les contrôles réguliers sont-ils recommandés ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des contrôles réguliers peuvent aider à détecter précocement les symptômes."
}
},
{
"@type": "Question",
"name": "Quels traitements sont efficaces contre le MPP+ ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des médicaments dopaminergiques et des thérapies physiques."
}
},
{
"@type": "Question",
"name": "La réhabilitation est-elle utile pour les patients exposés au MPP+ ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la réhabilitation aide à améliorer la mobilité et la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser des antioxydants pour traiter le MPP+ ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antioxydants peuvent être envisagés pour réduire le stress oxydatif lié au MPP+."
}
},
{
"@type": "Question",
"name": "Les thérapies complémentaires sont-elles bénéfiques ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines thérapies complémentaires, comme l'acupuncture, peuvent soulager les symptômes."
}
},
{
"@type": "Question",
"name": "Le traitement précoce du MPP+ est-il crucial ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un traitement précoce peut ralentir la progression des symptômes parkinsoniens."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le MPP+ ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des troubles moteurs sévères et des problèmes cognitifs."
}
},
{
"@type": "Question",
"name": "Le MPP+ peut-il entraîner des chutes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les troubles de la marche augmentent le risque de chutes chez les patients."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de dépression avec le MPP+ ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients exposés au MPP+ présentent un risque accru de dépression."
}
},
{
"@type": "Question",
"name": "Le MPP+ peut-il affecter la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes parkinsoniens peuvent significativement réduire la qualité de vie."
}
},
{
"@type": "Question",
"name": "Des complications cardiovasculaires sont-elles possibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études suggèrent un lien entre MPP+ et complications cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque du MPP+ ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition à des pesticides et à des produits chimiques industriels augmente le risque."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque pour le MPP+ ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque d'effets néfastes du MPP+ augmente avec l'âge."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux influencent-ils le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies neurodégénératives augmentent le risque."
}
},
{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le risque de MPP+ ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études montrent que les hommes sont plus à risque que les femmes."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il le risque de MPP+ ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent augmenter le risque."
}
}
]
}
]
}
Management of pediatric choroidal hemangioma complicated by large exudative retinal detachment can be challenging, with few options available. Limited data have been published on outcomes following pr...
The aim of this study was to ascertain the use of ocular imaging and the updated screening criteria in the evaluation of choroidal nevus across the United States....
Sixty ophthalmologists completed an anonymous 21-question survey addressing their use of the screening criteria for evaluating choroidal nevi, as well as their use of ultrasonography (US), optical coh...
The majority of respondents were from the Northeast (55%), worked in private practice (83%), and practiced general ophthalmology (42%). The 2009 criteria TFSOM-UHHD was used by 39 (65%) respondents, w...
From the survey of current practice patterns, we learned that there is a general trend of underutilization of the proper imaging modalities - and thus the criteria - in evaluating choroidal nevus. Mor...
To detect the vessel density of choriocapillaris (CC) vascular network in eyes affected by choroidal osteoma and in eyes complicated by macular neovascularization (MNV), using optical coherence tomogr...
In this retrospective study, twenty-eight eyes of 28 patients were divided into three groups: group 1 including patients with calcified choroidal osteoma, group 2 including patients with decalcified c...
We enrolled 12 eyes with calcified choroidal osteoma, 11 eyes with decalcified choroidal osteoma, and 5 eyes with decalcified choroidal osteoma complicated by MNV. The eyes with decalcified choroidal ...
OCTA allowed a quantitative evaluation of choriocapillaris vessel density in choroidal osteoma, in order to detect the changes of this vascular network, which could lead to the development of MNV. The...
ClinicalTrials.gov Identifier: NCT05342324....
Stereotactic irradiation is one of the treatment modalities for intraocular uveal melanoma. The study's purpose was to describe the background of stereotactic one-day session radiosurgery, how the com...
The group of 147 patients with choroidal melanoma was treated by stereotactic irradiation on the linear accelerator with a single dose of 35.0 Gy. During the standard treatment process the uveal melan...
In the group of patients, it was 70 (47.6%) males and 77 (52.4%) females. The tumor volume median was from MRI equal to 0.44 cm...
The calculation of the intraocular uveal tumor volume is a crucial part of the stereotactic irradiation treatment. The ultrasound volume measured values were in most of the cases higher than the measu...
This study uses OCT imaging to examine morphological changes at the chorioretinal interface of the choroidal melanoma biopsy site over time....
Liverpool Ocular Oncology Centre (LOOC), St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom....
Retrospective analysis of all patients who underwent 25G vitrector-assisted transretinal biopsy for choroidal melanoma between 1st Jan 2017 and 31st Dec 2019. The biopsy procedure does not involve ful...
Fifty-one patients met the criteria for inclusion. OCT analysis identified 2 characteristic morphologies following transretinal biopsy -a choroidal plugging of biopsy site (47.0%), or a flat retinal h...
OCT analysis has identified key morphological changes following transretinal choroidal melanoma biopsy. The morphologies identified may provide dynamic protective effects against vitreous flow into th...
BACKGROUND Choroidal melanoma is the most common primary intraocular tumor in adults. Most primary choroidal melanomas are unilateral and unifocal. Bilateral primary choroidal melanomas are considered...
These cases highlight the importance of monitoring choroidal nevi with benign imaging characteristics and the potential to quantify horizontal growth using optical coherence tomography (OCT), in the a...
This study aimed to present reports of two patients with pigmented choroidal tumors with low malignant potential based on their multimodal imaging features at the time of referral, but access to prior...
Two patients with pigmented, dome-shaped, subfoveal tumors were referred. Both tumors had basal diameters greater than 5 mm but no other risk factor for growth at the time of referral. Screening OCT s...
Horizontal growth of choroidal tumors can be established using sequential OCT scans in the absence of color fundus photography. Access to prior imaging can expedite the diagnosis of choroidal melanoma...
Choroid, ciliary body, and iris melanomas are often grouped as uveal melanoma, the most common intraocular primary malignancy. The purpose of the current study was to analyze the tumor profile of newl...
Medical records of patients referred to our service with initial diagnostic hypothesis of choroidal melanoma from July 2014 to June 2020 were analysed on demographics, diagnosis confirmation, tumor me...
From the 102 patients referred with the choroidal melanoma diagnosis hypothesis, 70 (68.62%) were confirmed. Mean measurements from the tumors in millimetres were: 9.19 ± 3.69 at height and 12.97 ± 3....
The results indicate a late diagnosis of choroidal melanoma cases referred to our service. Most enucleated cases could have been treated with brachytherapy if it was broadly available at the national ...
To investigate the swept-source optical coherence tomography (SS-OCT) and SS-OCT angiography (SS-OCTA) findings in circumscribed choroidal hemangioma (CCH) before and after treatment with transpupilla...
The clinical records of 21 eyes having CCH imaged with SS-OCT/SS-OCTA between September 2018 and December 2022 were evaluated....
SS-OCT examination in CCH showed dome-shaped appearance (100%), choroidal shadowing (100%), expansion of choroidal structures (100%), subretinal fluid (66.7%), intraretinal edema/schisis (33.3%), reti...
SS-OCT/SS-OCTA are useful non-invasive tools for imaging the structural/vascular changes in CCHs managed with TTT or ICG-TTT. On SS-OCTA, hyporeflective spaces localizing to edema/schisis in the DCP a...
To investigate the diagnostic value of optical density ratio (ODR) in various diseases with subretinal fluid (SRF) due to different pathophysiologies....
Patients with acute central serous chorioretinopathy, CSCR (n = 49), Vogt Koyanagi Harada disease, VKH (n = 34), and choroidal hemangioma (n = 17) characterized with SRF were included. Spectral-domain...
Optical density (OD) measurement was highly reproducible (intraclass correlation coefficient> 0.9). Optical density of the SRF, vitreous, RNFL, and signal strength were comparable (p = 0.360, p = 0.24...
ODR measurement appears to be a highly repeatable SD-OCT parameter for diseases characterized with SRF collection. Despite variations in their pathophysiology, the ODR was not statistically different ...