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Pyridines
Composés de pyridinium
1-Méthyl-4-phényl-pyridinium
1-Méthyl-4-phényl-pyridinium : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Maladie de Parkinson
Neurotoxicité
Imagerie par résonance magnétique
Électromyographie
Analyse sanguine
Toxicologie
Évaluation neurologique
Réflexes
Symptômes
5
Tremblements
Troubles de la marche
Troubles cognitifs
Démence
Système nerveux
Neurones dopaminergiques
Douleurs musculaires
Douleurs articulaires
Prévention
5
Prévention
Équipements de protection
Vaccins
Prévention des maladies
Mode de vie sain
Maladies neurodégénératives
Éducation à la santé
Sensibilisation
Contrôles médicaux
Détection précoce
Traitements
5
Médicaments dopaminergiques
Thérapie physique
Réhabilitation
Qualité de vie
Antioxydants
Stress oxydatif
Acupuncture
Thérapies complémentaires
Traitement précoce
Progression des symptômes
Complications
5
Complications
Troubles moteurs
Chutes
Troubles de la marche
Qualité de vie
Symptômes parkinsoniens
Complications cardiovasculaires
Santé cardiovasculaire
Facteurs de risque
5
Facteurs de risque
Pesticides
Antécédents familiaux
Maladies neurodégénératives
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"description": "Comment diagnostiquer l'exposition au MPP+ ?\nQuels examens sont recommandés pour le MPP+ ?\nQuels symptômes indiquent une intoxication au MPP+ ?\nLe MPP+ peut-il être détecté dans le sang ?\nQuels tests neurologiques sont utiles pour le MPP+ ?",
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"@type": "Question",
"name": "Comment diagnostiquer l'exposition au MPP+ ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests biologiques et des évaluations neurologiques sont utilisés pour diagnostiquer l'exposition."
}
},
{
"@type": "Question",
"name": "Quels examens sont recommandés pour le MPP+ ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IRM et l'électromyographie peuvent aider à évaluer les dommages neurologiques."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une intoxication au MPP+ ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tremblements, rigidité et bradykinésie peuvent indiquer une intoxication au MPP+."
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{
"@type": "Question",
"name": "Le MPP+ peut-il être détecté dans le sang ?",
"position": 4,
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{
"@type": "Question",
"name": "Quels tests neurologiques sont utiles pour le MPP+ ?",
"position": 5,
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"text": "Des tests de coordination et de réflexes peuvent évaluer l'impact neurologique du MPP+."
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{
"@type": "Question",
"name": "Quels sont les symptômes principaux du MPP+ ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les symptômes incluent tremblements, rigidité musculaire et troubles de la marche."
}
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{
"@type": "Question",
"name": "Le MPP+ cause-t-il des troubles cognitifs ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition au MPP+ peut entraîner des troubles cognitifs et de la mémoire."
}
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{
"@type": "Question",
"name": "Y a-t-il des symptômes non moteurs liés au MPP+ ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des symptômes comme la dépression et l'anxiété peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment le MPP+ affecte-t-il le système nerveux ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le MPP+ endommage les neurones dopaminergiques, entraînant des symptômes parkinsoniens."
}
},
{
"@type": "Question",
"name": "Le MPP+ provoque-t-il des douleurs ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs musculaires et articulaires peuvent être présentes chez les patients."
}
},
{
"@type": "Question",
"name": "Comment prévenir l'exposition au MPP+ ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les environnements contaminés et utiliser des équipements de protection."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccins contre le MPP+ ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de vaccin spécifique contre le MPP+."
}
},
{
"@type": "Question",
"name": "Les changements de mode de vie aident-ils à prévenir le MPP+ ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sain peut réduire le risque de maladies neurodégénératives."
}
},
{
"@type": "Question",
"name": "L'éducation sur le MPP+ est-elle importante ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'éducation sur les risques et les symptômes est essentielle pour la prévention."
}
},
{
"@type": "Question",
"name": "Les contrôles réguliers sont-ils recommandés ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des contrôles réguliers peuvent aider à détecter précocement les symptômes."
}
},
{
"@type": "Question",
"name": "Quels traitements sont efficaces contre le MPP+ ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des médicaments dopaminergiques et des thérapies physiques."
}
},
{
"@type": "Question",
"name": "La réhabilitation est-elle utile pour les patients exposés au MPP+ ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la réhabilitation aide à améliorer la mobilité et la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser des antioxydants pour traiter le MPP+ ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antioxydants peuvent être envisagés pour réduire le stress oxydatif lié au MPP+."
}
},
{
"@type": "Question",
"name": "Les thérapies complémentaires sont-elles bénéfiques ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines thérapies complémentaires, comme l'acupuncture, peuvent soulager les symptômes."
}
},
{
"@type": "Question",
"name": "Le traitement précoce du MPP+ est-il crucial ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un traitement précoce peut ralentir la progression des symptômes parkinsoniens."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le MPP+ ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des troubles moteurs sévères et des problèmes cognitifs."
}
},
{
"@type": "Question",
"name": "Le MPP+ peut-il entraîner des chutes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les troubles de la marche augmentent le risque de chutes chez les patients."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de dépression avec le MPP+ ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients exposés au MPP+ présentent un risque accru de dépression."
}
},
{
"@type": "Question",
"name": "Le MPP+ peut-il affecter la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes parkinsoniens peuvent significativement réduire la qualité de vie."
}
},
{
"@type": "Question",
"name": "Des complications cardiovasculaires sont-elles possibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études suggèrent un lien entre MPP+ et complications cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque du MPP+ ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition à des pesticides et à des produits chimiques industriels augmente le risque."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque pour le MPP+ ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque d'effets néfastes du MPP+ augmente avec l'âge."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux influencent-ils le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies neurodégénératives augmentent le risque."
}
},
{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le risque de MPP+ ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études montrent que les hommes sont plus à risque que les femmes."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il le risque de MPP+ ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent augmenter le risque."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 11/03/2025
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
Department of Studies in Chemistry University of Mysore, Manasagangotri, Mysore-570 006, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
3-Methyl-5-(4-methyl-phen-oxy)-1-phenyl-1
IUCrData
2022-09-27
Crystal structure studies of 4-ethyl-piperazin-1-ium 3,5-di-nitro-benzoate, 4-methyl-piperazin-1-ium 3,5-di-nitro-benzoate and 4-methyl-piperazin-1-ium 4-iodo-benzoate.
Acta crystallographica. Section E, Crystallographic communications
2021-10-21
Crystal-structure studies of 4-phenyl-piperazin-1-ium 4-eth-oxy-benzoate monohydrate, 4-phenyl-piperazin-1-ium 4-meth-oxy-benzoate monohydrate, 4-phenyl-piperazin-1-ium 4-methyl-benzoate monohydrate and 4-phenyl-piperazin-1-ium tri-fluoro-acetate 0.12-hydrate.
Acta crystallographica. Section E, Crystallographic communications
2022-06-10
5-(4-Fluoro-phen-yl)-1-[4-(4-methyl-phen-yl)thia-zol-2-yl]-3-[4-(prop-2-yn-yloxy)phen-yl]-4,5-di-hydro-1
IUCrData
2022-10-25
Syntheses and crystal structures of 4-(4-meth-oxy-phen-yl)piperazin-1-ium 4-methyl-benzoate monohydrate and bis-[4-(4-meth-oxy-phen-yl)piperazin-1-ium] benzene-1,2-di-carboxyl-ate.
Acta crystallographica. Section E, Crystallographic communications
2022-08-26
4 publications dans cette catégorie
Affiliations :
Department of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan. yuka@kms.ac.jp.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
4 publications dans cette catégorie
Affiliations :
Department of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
4 publications dans cette catégorie
Affiliations :
Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
4 publications dans cette catégorie
Affiliations :
Department of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
4 publications dans cette catégorie
Affiliations :
Department of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
3 publications dans cette catégorie
Affiliations :
Department of Chemistry, Howard University, 525 College Street NW, Washington DC 20059, USA.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
3 publications dans cette catégorie
Affiliations :
Department of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, Türkiye.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
Crystal structures and Hirshfeld surface analyses of methyl 4-{2,2-di-chloro-1-[(
Acta crystallographica. Section E, Crystallographic communications
2024-01-26
Crystal-structure studies of 4-phenyl-piperazin-1-ium 4-eth-oxy-benzoate monohydrate, 4-phenyl-piperazin-1-ium 4-meth-oxy-benzoate monohydrate, 4-phenyl-piperazin-1-ium 4-methyl-benzoate monohydrate and 4-phenyl-piperazin-1-ium tri-fluoro-acetate 0.12-hydrate.
Acta crystallographica. Section E, Crystallographic communications
2022-06-10
Crystal structures of 1-(4-chloro-phen-yl)-4-(4-methyl-phen-yl)-2,5-dioxo-1,2,5,6,7,8-hexa-hydro-quinoline-3-carb-oxy-lic acid and 4-(4-meth-oxy-phen-yl)-1-(4-methyl-phen-yl)-2,5-dioxo-1,2,5,6,7,8-hexa-hydro-quinoline-3-carbo-nitrile.
Acta crystallographica. Section E, Crystallographic communications
2021-03-05
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Neuroprotective Drug Discovery Center, Nanjing Medical University, Nanjing, China.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Division of Clinical Pharmacy, Department of Pharmacy, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Neuroprotective Drug Discovery Center, Nanjing Medical University, Nanjing, China.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Studies in Chemistry University of Mysore, Manasagangotri, Mysore-570 006, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Studies in Chemistry Mangalore University Mangalagangotri, Mangalore-574 199, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Studies in Chemistry Mangalore University Mangalagangotri, Mangalore-574 199, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Thomas Jefferson High School for Science and Technology, 6560 Braddock Rd Alexandria VA 22312, USA.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry and Biochemistry, School of Basic Sciences and Research, Sharda University, Greater Noida 201306, India.
Department of Chemistry, Pondicherry University, Puducherry 605 014, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Pondicherry University, Puducherry 605 014, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida 201306, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
2 publications dans cette catégorie
Affiliations :
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570 006, India.
Publications dans "1-Méthyl-4-phényl-pyridinium" :
Our goal was to evaluate the clinical behavior of resin-based composite (RBC) restorations with sealed marginal defects using nano-filled flowable RBCs (FRS) compared with resin-based sealant (RBS); t...
This was a prospective, randomized, double-blind, controlled trial. Fifty-four patients who met the inclusion criteria (older than 18 years old; with high cariogenic risk determined by Cariogram softw...
Marginal adaptation of micro-repaired RBC restorations were seen in patients with a high risk of caries using flowable resin composite or resin-based sealants. There were differences (P < 0.001) when ...
Micro-repair of RBC restorations resulted in clinical deterioration of marginal adaptation and marginal staining. Nano-filled flowable resin composites were sealed on defective restorations; 3 and 4 F...
Micro-repair with RBS does not seem to be an effective treatment to prevent secondary caries....
Photoactivating dental resin composites have been the most prevailing material for repairing dental defects in various clinical scenarios due to their multiple advantages. However, compared to other r...
The aim of this scoping review was to analyze the available evidence on the preheating process and its effects on physicochemical properties of composite resins....
A systematic search was performed in August 2021 using PubMed/Medline, Embase, Scopus, and ISI Web of Science databases and gray literature without language or date restriction. Inclusion criteria wer...
In total, 104 studies were found from which 39 were included. The most used composite resin was Filtek Z350 XT (3 M/ESPE), preheated at 68°C in a Calset device (AdDent Inc., Danbury, CT, USA) for 5 or...
The parameters used for preheating composite resins are heterogeneous. Preheating decreased viscosity, increased the conversion degree and microhardness of composite resins, and improved the marginal ...
The analysis of evidence showed a high heterogeneity among preheating protocols. Preheating may benefit the handling and physicochemical properties of composite resins....
To map the existing evidence regarding the masking ability of resin composites....
The literature search was conducted electronically, based on the PRISMA Extension for Scoping Reviews-online protocol at https://osf.io/m2h67/ with no language or time restrictions. Two independent re...
Acceptable masking of C4 shade background is achieved with one layer of opaque shade composite at least 0.5 mm-thick or by different combinations of the layering technique, with a final thickness of 1...
The thickness of the resin composite layer required to achieve adequate masking is variable and depends on the translucency/opacity of the tested resin composites and the background shade....
Albumin is a salivary enzyme capable of cleaving ester linkages and catalyzing degradation of resin-based dental materials. However, the effect of concentration-dependent esterolytic action on composi...
The purpose of this study was to evaluate whether artificial saliva formulations with different concentrations of albumin affected the surface roughness, flexural strength and microhardness of a compo...
Specimens (25x2x2mm) of a nanofilled composite (Filtek Z350XT, 3M/ESPE) were prepared and analyzed for average surface roughness (Ra/pm). The specimens were then allocated to 6 groups (n=30), to be tr...
Although Ra increased (p < 0.001) and FS decreased (p < 0.001) from 24 hours to 180 days of storage, the albumin concentration did not significantly affectRa (p = 0.168), FS (p = 0.477) or KH (p = 0.3...
The esterolytic action of albumin did not increase the artificial-saliva-induced hydrolytic degradation of the composite resin....
To compare the clinical performance (retention, secondary caries, marginal adaptation, marginal discoloration, and postoperative hypersensitivity) of self-adhesive flowable composite resins (SAFCs) an...
Randomized controlled trials (RCTs) of SAFCs versus FCs with a follow-up length of at least one year. No restrictions were placed on language or publication date....
Five databases, including PubMed, Embase, Web of Science, Scopus, and the Cochrane Central Register of Controlled Trials, were searched manually by browsing ten related journals. On 14 June 2023, all ...
Five RCTs with 138 participants were included. Cochrane's risk of bias tool (2.0) was implemented in selected studies, and the GRADE tool was utilised to evaluate the evidence quality. To summarize th...
According to the modified United States Public Health Service Evaluation (USPHS) criteria, there was no discernible difference between the groups during the two-year follow-up period (maximum follow-u...
SAFCs exhibited clinical performance comparable to that of FCs in occlusal cavities. Further high-quality clinical trials are needed to provide solid evidence to support the clinical application of SA...
PROSPERO (CRD42022374983)....
Warming composite resin before insertion to reduce viscosity is advocated for improving adaptation and reducing voids. This study evaluated how prewarming altered porosities, adaptation, and strength....
This article discusses potential concerns and important considerations when selecting and using matrix transfer techniques for the direct, definitive addition of composite resin to teeth. It also prov...
Regular composites could produce less polymerization stress than resin cements when luting laminate veneers but there is no proper evidence to support this theory. The current study aimed to determine...
The study considered (i) regular resin composites (Admira Fusion, Gradia, Grandioso, Palfique, Sirius Z, Viscalor and Z100) at room and pre-warmed (PW) at 69ºC, (ii) flowable composites (Sigma Flow an...
For regular composites, the pre-warming did not affect DC, shrinkage and modulus but significantly increased the stress magnitude. Correlation tests indicated a significant relationship only between s...
Regular composites can produce less polymerization stress than resin cements when luting laminate veneers. Polymerization stress was dependent on the shrinkage magnitude, but not on the degree of conv...
This paper summarizes the effective components of computer-aided design and computer-aided manufacturing (CAD-CAM) resin composites that contribute to achieving greater mechanical properties and furth...
In silico multi-scale analysis, in silico nonlinear dynamic finite element analysis (FEA), and artificial intelligence (AI) were used to explore the effective components of CAD-CAM resin composites. T...
As the filler diameter decreases, there is an increase in elastic moduli and compressive strengths at the macroscale. At the nanoscale, a decrease in the filler diameter results in a decrease in the m...
This paper summarized the effective components of CAD-CAM resin composites for their further development. The integration of in vitro and in silico approaches will expedite the advancement of CAD-CAM ...