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"name": "Diagnostic",
"headline": "Diagnostic sur Colle de fibrine",
"description": "Comment évaluer l'efficacité de la colle de fibrine ?\nQuels tests sont utilisés avant l'application ?\nY a-t-il des contre-indications à son utilisation ?\nComment détecter une réaction allergique ?\nQuels signes indiquent une mauvaise cicatrisation ?",
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"description": "Comment la colle de fibrine est-elle appliquée ?\nQuels types de blessures peuvent être traités ?\nLa colle de fibrine remplace-t-elle les sutures ?\nQuels soins sont nécessaires après application ?\nPeut-on utiliser la colle de fibrine en cas d'infection ?",
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"headline": "Facteurs de risque sur Colle de fibrine",
"description": "Quels sont les principaux facteurs de risque ?\nLes personnes âgées sont-elles plus à risque ?\nLes maladies chroniques influencent-elles le risque ?\nComment le tabagisme affecte-t-il le risque ?\nLes antécédents chirurgicaux augmentent-ils le risque ?",
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"@type": "Question",
"name": "Comment évaluer l'efficacité de la colle de fibrine ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité est évaluée par l'observation de la cicatrisation et la réduction des hémorragies."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés avant l'application ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de coagulation sanguine peuvent être réalisés pour évaluer la compatibilité."
}
},
{
"@type": "Question",
"name": "Y a-t-il des contre-indications à son utilisation ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les allergies aux composants de la colle ou des troubles de la coagulation sont des contre-indications."
}
},
{
"@type": "Question",
"name": "Comment détecter une réaction allergique ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une réaction allergique peut se manifester par des rougeurs, démangeaisons ou gonflements au site d'application."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une mauvaise cicatrisation ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme une inflammation persistante, une déhiscence ou une infection peuvent indiquer une mauvaise cicatrisation."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent apparaître après l'application ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des rougeurs, gonflements ou douleurs au site d'application peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une infection post-opératoire ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une infection peut se manifester par une chaleur, une douleur accrue, ou un écoulement purulent."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires fréquents ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires peuvent inclure des démangeaisons ou des réactions au site d'application."
}
},
{
"@type": "Question",
"name": "Quels signes d'allergie doivent alerter ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des éruptions cutanées, des démangeaisons ou un œdème peuvent indiquer une allergie."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des douleurs persistantes ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs persistantes peuvent survenir, nécessitant une évaluation médicale."
}
},
{
"@type": "Question",
"name": "Comment prévenir les infections après application ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une bonne hygiène et suivre les instructions post-opératoires aide à prévenir les infections."
}
},
{
"@type": "Question",
"name": "Quelles précautions prendre avant l'application ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évaluer les allergies et les antécédents médicaux est essentiel avant l'application."
}
},
{
"@type": "Question",
"name": "Comment éviter les réactions allergiques ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un test cutané préalable peut aider à identifier les allergies potentielles aux composants."
}
},
{
"@type": "Question",
"name": "Y a-t-il des recommandations pour les patients ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients doivent suivre les conseils médicaux et signaler tout symptôme inhabituel."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque doivent être surveillés ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents d'allergies et les troubles de la coagulation sont des facteurs de risque importants."
}
},
{
"@type": "Question",
"name": "Comment la colle de fibrine est-elle appliquée ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est généralement appliquée par pulvérisation ou en gouttes sur les tissus à unir."
}
},
{
"@type": "Question",
"name": "Quels types de blessures peuvent être traités ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est utilisée pour des coupures, des incisions chirurgicales ou des lésions cutanées."
}
},
{
"@type": "Question",
"name": "La colle de fibrine remplace-t-elle les sutures ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut remplacer les sutures dans certains cas, mais n'est pas toujours appropriée."
}
},
{
"@type": "Question",
"name": "Quels soins sont nécessaires après application ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est important de garder la zone propre et sèche, et de surveiller les signes d'infection."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser la colle de fibrine en cas d'infection ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, son utilisation est contre-indiquée en présence d'une infection active."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des infections, des réactions allergiques ou une mauvaise cicatrisation peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment gérer une réaction allergique ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "En cas de réaction allergique, il est crucial de consulter un médecin immédiatement."
}
},
{
"@type": "Question",
"name": "Quels signes d'infection nécessitent une attention médicale ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des rougeurs, chaleur, douleur accrue ou écoulement purulent nécessitent une attention médicale."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des cicatrices après utilisation ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des cicatrices peuvent se former, surtout si la cicatrisation est compromise."
}
},
{
"@type": "Question",
"name": "Quelles sont les conséquences d'une mauvaise application ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une mauvaise application peut entraîner des déhiscences, infections ou cicatrisation inadéquate."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les allergies, les troubles de la coagulation et les infections antérieures sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "Les personnes âgées sont-elles plus à risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées peuvent avoir un risque accru de complications lors de l'utilisation."
}
},
{
"@type": "Question",
"name": "Les maladies chroniques influencent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme le diabète peuvent augmenter le risque d'infection et de mauvaise cicatrisation."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme affecte-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme peut retarder la cicatrisation et augmenter le risque d'infections."
}
},
{
"@type": "Question",
"name": "Les antécédents chirurgicaux augmentent-ils le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents de complications chirurgicales peuvent augmenter le risque lors de nouvelles interventions."
}
}
]
}
]
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Hemorrhage following pancreatectomy represents a grave complication, exerting a significant impact on patient prognosis. The formulation of a precise predictive model for postpancreatectomy hemorrhage...
This study utilized the patient cohort from the American College of Surgeons National Surgical Quality Improvement Program database, who underwent pancreatectomy between 2014 and 2017 (n=5779), as the...
In the training and validation cohorts, 9.0% (520/5779) and 8.5% (328/3852) of patients, respectively, experienced postpancreatectomy hemorrhage. Following selection via lasso and logistic regression,...
The Lasso-logistic predictive model we developed, constructed from nine rigorously selected variables, accurately predicts the risk of PPH. It has the potential to significantly enhance the safety of ...
Branch atheromatous disease (BAD) is a form of ischemic stroke that presents with imaging findings similar to those of lacunar infarction, but has a different pathogenesis and is known to cause progre...
In this multicenter cohort study, we retrospectively analyzed data from the Saiseikai Stroke Database (2013-2021) including 27 hospitals. We used multivariable logistic regression to calculate adjuste...
Of the 5,966 analyzed patients, 1,549 (25.9%) had BAD and 4,434 (74.1%) had LI. BAD was associated with worse functional outcomes (adjusted OR of 2.77, 95%CI: 2.42-3.17, relative to LI) and extended h...
BAD presented worse functional outcomes and longer hospital stays than LI, necessitating treatment plans that take into account its progression and prognosis....
To compare the efficacy and safety of a fixed-dose combination of aspirin and pantoprazole with that of aspirin alone for the prevention of gastro duodenal mucosal damage in patients taking aspirin fo...
This was a comparative, double-blind, double-dummy, randomized, multicenter, phase III study conducted in patients taking aspirin ≤ 150 mg daily for ≥3 to ≤6 months and expected to require daily aspir...
A total of 240 patients were randomized to receive either a fixed-dose combination of aspirin 150 mg and pantoprazole 20 mg or aspirin 150 mg alone in a 2:1 ratio. The proportion of non-responders (pa...
The fixed-dose combination of aspirin 150 mg and pantoprazole 20 mg was found to be more efficacious and safer compared to aspirin 150 mg alone for the prevention of gastroduodenal mucosal damage in p...
A sex-based evaluation of prognosis in heart failure (HF) is lacking....
We analyzed the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score registry, which includes HF with reduced ejection fraction (HFrEF) patients. A cross-validation proc...
S-MECKI, i.e., the recalibrated MECKI according to sex-specific differences, constitutes a further step in the prognostic assessment of patients with severe HFrEF....
Carotid intima-media thickness (IMT) and diameter, stiffness, and wave reflections, are independent and important clinical biomarkers and risk predictors for cardiovascular diseases. The purpose of th...
A total of 3053 healthy Han Chinese adults (1922 women) aged 18-79 years were enrolled at 28 collaborating tertiary centers throughout China between April 2021 and July 2022. The real-time tracking of...
All the parameters of carotid properties demonstrated significantly age-related trajectories. Women showed thinner IMT, smaller carotid diameter, larger AP, and AIx than men. The β stiffness and PWV w...
The age- and sex-specific reference values of carotid properties measured by RF ultrasound for healthy Chinese adults were established. The blood pressures, BMI, and triglyceride levels should be cons...
This study aimed to clarify the relation between global spinal alignment and the necessity of walking aid use in patients with adult spinal deformity (ASD) and to investigate the impact of spinal fixa...
In total, 456 older patients with ASD who had multi-segment spinal fixation surgery and were registered in a multi-center database were investigated. Patients under 60 years of age and those unable to...
Of 261 patients analyzed, 66 used walking aids (canes, 46; walkers, 20). Analysis of preoperative radiographical parameters showed increased pelvic incidence and pelvic incidence-lumbar lordosis misma...
A significant correlation was found between "sagittal" spinal imbalance and increased reliance on walking aids, particularly walkers. However, the limitation of improvement in postoperative mobility s...
In amyotrophic lateral sclerosis (ALS) caused by SOD1 mutations (SOD1-ALS), tofersen received accelerated approval in the United States and is available via expanded access programs (EAP) outside the ...
Sixteen SOD1-ALS patients receiving tofersen for at least 6 months were analyzed. The ALS progression rate (ALS-PR), as measured by the monthly change of the ALS functional rating scale-revised (ALSFR...
Mean tofersen treatment was 11 months (6-18 months). ALS-PR showed a mean change of -0.2 (range 0 to -1.1) and relative reduction by 25%. Seven patients demonstrated increased ALSFRS-R. SVC was stable...
Data from this EAP supported the clinical and sNfL response to tofersen in SOD1-ALS. PRO suggested a favorable patient perception of tofersen treatment in clinical practice....
Limited evidence exists regarding the link between platelet count and 30-day in-hospital mortality in acute respiratory failure (ARF) patients. Thus, this study aims to investigate this association am...
We conducted a retrospective cohort study across multiple centers, utilizing data from the US eICU-CRD v2.0 database covering 22,262 patients with ARF in the ICU from 2014 to 2015. Our aim was to inve...
The 30-day in-hospital mortality rate was 19.73% (4393 out of 22,262), with a median platelet count of 213 × 10...
This study establishes a clear negative association between platelet count and 30-day in-hospital mortality among ICU patients with ARF. Furthermore, we have identified a nonlinear relationship with s...
We aimed to investigate the relationship between admission hypothermia and outcomes among very preterm infants (VPIs) in neonatal intensive care units (NICUs) in China. We also investigated the freque...
This retrospective cohort study enrolled infants with 24...
A total of 5,913 VPIs were included in this study, of which 4,075 (68.9%) had hypothermia (<36.5 °C) at admission. The incidence of admission hypothermia varied widely across CHNN sites (9-100%). Lowe...
Admission hypothermia remains a common problem for VPIs in a large cohort in China and is associated with adverse outcomes. Continuous quality improvement of admission hypothermia in the future may re...
· Admission hypothermia is common in VPIs.. · The incidence of admission hypothermia in VPIs remains high in China.. · Admission hypothermia is associated with adverse outcomes in VPIs.....
Our aim was to develop a machine learning-based predictor for early mortality and severe intraventricular hemorrhage (IVH) in very-low birth weight (VLBW) preterm infants in Taiwan. We collected retro...